Opportunity Information: Apply for RFA DA 09 011

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "2009 NIDA Avant Garde Award Program for HIV/AIDS Research (DP1)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
  • This funding opportunity was created on Dec 11, 2008 and posted on Dec 11, 2008.
  • Applicants must submit their applications by Jun 2, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Native American tribal governments (Federally recognized) Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) State governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
Apply for RFA DA 09 011

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Opportunity Summary:

The 2009 NIDA Avant Garde Award Program for HIV/AIDS Research (DP1), announced by the National Institutes of Health through the National Institute on Drug Abuse (NIDA), is a discretionary grant opportunity designed to push the field forward by backing unusually creative scientists with bold ideas. The central goal is to complement NIDA's standard investigator-initiated funding by specifically targeting high-impact, potentially game-changing research that can open entirely new directions for preventing and treating HIV/AIDS in the context of drug abuse. In practical terms, the program is looking for proposals that are not just incremental improvements, but that could reshape how researchers understand or intervene in HIV/AIDS among people who use drugs.

A defining feature of this competition is its two-phase application structure. The first phase was a pre-application stage submitted under a related announcement (PAR 09-044). Those pre-applications were reviewed by external experts, and only the strongest, most outstanding submissions were invited to move forward. Investigators who were selected from that initial screening were then given the opportunity to submit a full application under this specific funding opportunity announcement (FOA), which uses the DP1 grant mechanism. Final award decisions for the 2009 Avant Garde Award were made from among the invited full applications, meaning the program is inherently selective and focused on identifying a small number of exceptionally promising, high-risk/high-reward projects.

From an administrative and funding standpoint, this opportunity is identified as Funding Opportunity Number RFA-DA-09-011 and is tied to CFDA number 93.279 (Drug Abuse and Addiction Research Programs). It was posted on December 11, 2008, with an application closing date of June 2, 2009, and it was later archived on July 3, 2009. The award ceiling is listed as $500,000, and the announcement indicates there is no cost-sharing or matching requirement, which means applicants were not required to provide additional non-federal funds as a condition of receiving the grant.

Eligibility is broad and includes a wide range of organization types, reflecting NIH's typical openness to strong research proposals across sectors. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), for-profit organizations other than small businesses, and small businesses. The eligibility list also explicitly includes state governments, federally recognized Native American tribal governments, and tribal organizations that are not federally recognized. Additional eligible categories are also noted, such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based and community-based organizations, regional organizations, eligible federal government agencies, and U.S. territories or possessions. This wide eligibility framework suggests the program was primarily focused on the caliber and originality of the proposed science and the investigator's creativity, rather than limiting participation to a narrow set of institutions.

Overall, the grant opportunity can be understood as a targeted NIH initiative to accelerate innovative HIV/AIDS research where drug abuse is a key driver of risk, transmission, or barriers to care. By using a phased approach that filters applicants through an initial pre-application review and by relying on the DP1 mechanism, NIDA structured the program to identify and support a small cohort of investigators whose ideas have the potential to create new research avenues and ultimately improve prevention and treatment outcomes for a population disproportionately affected by both substance use and HIV/AIDS. For full details, the original announcement was hosted on the NIH grants website under the link provided in the posting (RFA-DA-09-011).

FAQs: 2009 NIDA Avant Garde Award Program for HIV/AIDS Research (DP1) - RFA-DA-09-011

What is the 2009 NIDA Avant Garde Award Program for HIV/AIDS Research (DP1)?

It is a discretionary grant opportunity from the National Institutes of Health (NIH), specifically the National Institute on Drug Abuse (NIDA), designed to support unusually creative scientists with bold ideas aimed at advancing HIV/AIDS research in the context of drug abuse. It uses the NIH DP1 grant mechanism.

What is the main purpose of this funding opportunity?

The central goal is to complement NIDA's standard investigator-initiated funding by targeting high-impact, potentially game-changing research that could open entirely new directions for preventing and treating HIV/AIDS where drug abuse is a key driver of risk, transmission, or barriers to care.

What kind of research is this program trying to fund?

The program is looking for projects that go beyond incremental improvements. It emphasizes high-risk/high-reward proposals that could reshape how researchers understand or intervene in HIV/AIDS among people who use drugs.

Is this award intended for incremental or conventional research projects?

No. Based on the announcement description, the competition is specifically geared toward bold, unusually creative, and potentially field-shifting research rather than incremental advances.

Which NIH institute administers this opportunity?

The opportunity is administered by the National Institute on Drug Abuse (NIDA) within the National Institutes of Health (NIH).

What is the Funding Opportunity Number for this announcement?

The Funding Opportunity Number is RFA-DA-09-011.

What CFDA number is associated with this opportunity?

The opportunity is tied to CFDA 93.279 (Drug Abuse and Addiction Research Programs).

What grant mechanism does this program use?

The program uses the DP1 grant mechanism.

How did the two-phase application process work?

The competition used a phased approach. First, investigators submitted a pre-application under a related announcement (PAR 09-044). Those pre-applications were reviewed by external experts, and only the strongest submissions were invited to submit a full application under this FOA (RFA-DA-09-011).

Was everyone allowed to submit a full application?

No. Full applications were only accepted from investigators who were invited after the pre-application stage review.

Who reviewed the pre-applications?

Pre-applications were reviewed by external experts, and only the most outstanding were invited to proceed.

How were final award decisions made?

Final award decisions were made from among the invited full applications submitted under this FOA, reflecting a selective process focused on exceptionally promising projects.

How competitive or selective is this program described to be?

It is described as inherently selective because only a subset of applicants were invited to submit full applications after external expert review, and awards were made only from the invited pool.

What is the award ceiling?

The award ceiling is listed as $500,000.

Is cost-sharing or matching required?

No. The announcement indicates there is no cost-sharing or matching requirement, meaning applicants were not required to provide additional non-federal funds as a condition of receiving the grant.

When was this funding opportunity posted?

It was posted on December 11, 2008.

What was the application closing date?

The application closing date was June 2, 2009.

Is this funding opportunity still active?

No. The announcement was archived on July 3, 2009.

Who is eligible to apply?

Eligibility is broad and includes many organization types: public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations (both 501(c)(3) and non-501(c)(3)); for-profit organizations other than small businesses; small businesses; state governments; federally recognized Native American tribal governments; and tribal organizations that are not federally recognized.

Are U.S. territories or possessions eligible?

Yes. The eligibility list explicitly includes U.S. territories or possessions.

Are faith-based or community-based organizations eligible?

Yes. Faith-based and community-based organizations are explicitly included as eligible applicants.

Are minority-serving institutions included in the eligibility list?

Yes. The eligibility list includes Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).

Are tribal organizations eligible even if they are not federally recognized?

Yes. The eligibility list explicitly includes tribal organizations that are not federally recognized, in addition to federally recognized Native American tribal governments.

Are federal government agencies eligible to apply?

Yes. The eligibility list includes eligible federal government agencies.

Does the program prioritize any specific sector (academia vs. nonprofit vs. business)?

The description suggests the program primarily emphasizes the caliber and originality of the proposed science and the investigator's creativity rather than restricting participation to a narrow institution type, given the wide range of eligible organizations.

What topic area does the program focus on within HIV/AIDS research?

It targets HIV/AIDS research in which drug abuse is a key driver of risk, transmission, or barriers to prevention and treatment, with the goal of improving outcomes for populations affected by both substance use and HIV/AIDS.

Where were full details originally posted?

The original announcement was hosted on the NIH grants website under the posting for RFA-DA-09-011.

What related announcement was used for the pre-application stage?

The pre-application stage was submitted under PAR 09-044, and only selected applicants from that stage were invited to submit a full application under RFA-DA-09-011.

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Applicants also applied for:

Applicants who have applied for this opportunity (RFA DA 09 011) also looked into and applied for these:

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NCI Mentored Patient Oriented Research Career Development Award to Promote Diversity (K23) Apply for PAR 09 051

Funding Number: PAR 09 051
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NCI Mentored Research Scientist Development Award to Promote Diversity (K01) Apply for PAR 09 052

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Mechanism for Time Sensitive Research Opportunities (R03) Apply for PAR 06 249

Funding Number: PAR 06 249
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Support Opportunity for Addiction Research (SOAR) for New Investigators (R03) Apply for RFA DA 09 021

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Tools for Germplasm Cryopreservation (SBIR) R43/R44 Apply for PA 09 055

Funding Number: PA 09 055
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Pre application for a Biomedical Technology Research Resource (X02) Apply for PAR 08 260

Funding Number: PAR 08 260
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NIH Supported Centers for Population Health and Health Disparities (CPHHD) (P50) Apply for RFA CA 09 001

Funding Number: RFA CA 09 001
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Informatics Training for Global Health (ITGH) (D43) Apply for RFA TW 09 001

Funding Number: RFA TW 09 001
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Comprehensive Minority Institution/Cancer Center Partnership (Limited Competition U54) Apply for RFA CA 09 501

Funding Number: RFA CA 09 501
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Funding Number: PAR 08 055
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