Opportunity Information: Apply for RFA RM 09 001

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "2009 NIH Directors Pioneer Award Program (DP1)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
  • This funding opportunity was created on Oct 27, 2008 and posted on Oct 27, 2008.
  • Applicants must submit their applications by May 15, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Small businesses Native American tribal governments (Federally recognized) For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The 2009 NIH Director's Pioneer Award Program (DP1) is a competitive NIH grant opportunity designed to back individual scientists who show exceptional creativity and who want to pursue bold, high-risk research ideas that could significantly change the direction of biomedical or behavioral science. The central aim is to complement NIH's more traditional investigator-initiated funding by giving researchers room to try approaches that are genuinely unconventional. A key expectation is that the proposed work is "pioneering," meaning it should be substantially different from what the applicant is already doing in their own laboratory and also different from lines of work commonly being pursued elsewhere. In other words, this program is meant for ideas that feel like a real leap rather than a logical next step in an established project. The award sits within NIH's broader High Risk Research efforts under the NIH Roadmap for Medical Research, signaling that novelty and potential impact are weighted heavily in the competition.

The 2009 competition uses a two-phase submission and review process. The first step is a pre-application phase, which was run under a separate announcement (PAR 09-012). Those pre-applications are reviewed by external experts, and only the most outstanding submissions are invited to move forward. If an investigator is selected in that initial screening, they are notified and given the chance to submit a full application under the main funding opportunity announcement for the DP1 mechanism (RFA-RM-09-001). Final 2009 Pioneer Award recipients are chosen from the pool of applicants who are invited to submit full applications. An important practical detail is that applicants are expected to read and follow both announcements because the pre-application and full application stages are linked and the program requirements span both documents.

From a funding standpoint, NIH planned approximately $5 million total committed across the full five-year project period for the 2009 cohort, with an anticipated number of awards in the range of at least five to ten. The award mechanism is the DP1 grant mechanism, which is specifically associated with the NIH Director's Pioneer Award and is intended to support a person and their transformative idea rather than a narrowly defined set of incremental aims. There is no cost sharing or matching requirement listed for this opportunity, which means applicants are not expected to supply additional non-federal funds as a condition of receiving the award.

Administratively, this is a discretionary grant opportunity in the health area, listed under CFDA 93.310 (Trans-NIH Research Support) and sponsored by the National Institutes of Health. The posting date for the announcement was October 27, 2008, and the closing date for the full application stage was May 15, 2009, with archiving on June 15, 2009. The eligible applicant landscape is broad and includes many organization types, such as public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including both 501(c)(3) and non-501(c)(3) entities), small businesses, other for-profit organizations, state governments, and a wide variety of tribal and community-based entities. The eligibility language also explicitly includes organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), eligible federal agencies, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions, among others. For applicants who have trouble accessing the full announcement online or encounter technical issues, NIH directs them to the NIH Office of Extramural Research (OER) webmaster contacts listed in the notice.

Frequently Asked Questions (FAQs): 2009 NIH Director's Pioneer Award Program (DP1)

What is the 2009 NIH Director's Pioneer Award Program (DP1)?

The 2009 NIH Director's Pioneer Award Program (DP1) is a competitive NIH grant opportunity intended to support individual scientists who demonstrate exceptional creativity and who want to pursue bold, high-risk research ideas with the potential to substantially shift the direction of biomedical or behavioral science.

What kind of research is this program trying to support?

The program is meant to enable genuinely unconventional, high-risk approaches that may be difficult to fund through more traditional investigator-initiated NIH mechanisms. Novelty and potential impact are central considerations, consistent with its placement within NIH's broader High Risk Research efforts under the NIH Roadmap for Medical Research.

What does NIH mean by "pioneering" for this award?

"Pioneering" is treated as a key expectation. The proposed work should be substantially different from what the applicant is already doing in their own laboratory and also different from research directions commonly being pursued elsewhere. The intent is to back an idea that represents a real leap rather than a straightforward next step in an established program of work.

How does this award complement traditional NIH funding?

The central aim is to complement NIH's more traditional investigator-initiated funding by providing space for investigators to try approaches that are genuinely unconventional, where the potential payoff is high but the risk and uncertainty may also be high.

Is this opportunity part of any larger NIH initiative?

Yes. The Pioneer Award sits within NIH's broader High Risk Research efforts under the NIH Roadmap for Medical Research, which signals that novelty and the potential for major impact are weighted heavily in the competition.

What is the submission and review process for the 2009 competition?

The 2009 competition uses a two-phase submission and review process: (1) a pre-application phase and (2) an invited full application phase. Pre-applications are reviewed by external experts, and only the most outstanding submissions are invited to submit a full application under the main funding opportunity announcement for the DP1 mechanism.

What announcement covers the pre-application phase?

The pre-application phase was run under a separate announcement: PAR 09-012.

What announcement covers the full application phase?

Full applications are submitted under the main funding opportunity announcement for the DP1 mechanism: RFA-RM-09-001.

Do applicants need to pay attention to both announcements?

Yes. Applicants are expected to read and follow both announcements because the pre-application and full application stages are linked, and the program requirements span both documents.

Who selects which applicants can submit a full application?

External experts review the pre-applications, and only the most outstanding submissions are invited to move forward to the full application stage.

How are final 2009 Pioneer Award recipients chosen?

Final 2009 Pioneer Award recipients are chosen from the pool of applicants who are invited to submit full applications under RFA-RM-09-001.

What is the funding mechanism for this opportunity?

The award mechanism is the DP1 grant mechanism, which is specifically associated with the NIH Director's Pioneer Award and is intended to support a person and their transformative idea rather than a narrowly defined set of incremental aims.

How much total funding was NIH planning for the 2009 cohort?

NIH planned approximately $5 million total committed across the full five-year project period for the 2009 cohort.

How many awards did NIH anticipate making?

The anticipated number of awards was in the range of at least five to ten.

How long is the overall project period referenced for this cohort?

The information provided describes an approximate total commitment across a full five-year project period for the 2009 cohort.

Is cost sharing or matching required?

No. There is no cost sharing or matching requirement listed for this opportunity, meaning applicants are not expected to provide additional non-federal funds as a condition of receiving the award.

What type of grant is this administratively?

This is described as a discretionary grant opportunity in the health area, sponsored by the National Institutes of Health (NIH).

What is the CFDA number for this opportunity?

The opportunity is listed under CFDA 93.310 (Trans-NIH Research Support).

When was the announcement posted?

The posting date for the announcement was October 27, 2008.

What was the closing date for the full application stage?

The closing date for the full application stage was May 15, 2009.

When was the opportunity archived?

The opportunity was archived on June 15, 2009.

Who is the sponsoring agency?

The sponsoring agency is the National Institutes of Health (NIH).

What types of organizations are eligible to apply?

The eligible applicant landscape is broad. It includes public and state-controlled institutions of higher education; private institutions of higher education; nonprofits (including both 501(c)(3) and non-501(c)(3) entities); small businesses; other for-profit organizations; state governments; and a variety of tribal and community-based entities.

Are minority-serving institutions and specialized organization types included in eligibility?

Yes. The eligibility language explicitly includes organization types such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities (TCCUs), among others.

Are faith-based and community-based organizations eligible?

Yes. Faith-based or community-based organizations are explicitly included in the eligibility language described.

Are U.S. territories or possessions included as eligible applicants?

Yes. The eligibility language includes U.S. territories or possessions.

Are eligible federal agencies included as potential applicants?

Yes. The eligibility language explicitly includes eligible federal agencies.

What should applicants do if they cannot access the full announcement online or have technical problems?

NIH directs applicants who have trouble accessing the full announcement online or who encounter technical issues to the NIH Office of Extramural Research (OER) webmaster contacts listed in the notice.

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