Opportunity Information: Apply for RFA RM 09 010

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "2010 NIH Directors Pioneer Award Program (DP1)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
  • This funding opportunity was created on Aug 18, 2009 and posted on Aug 18, 2009.
  • Applicants must submit their applications by Oct 20, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses For profit organizations other than small businesses Public and State controlled institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The 2010 NIH Directors Pioneer Award Program (DP1) is a National Institutes of Health funding opportunity designed to sit alongside (and not replace) NIH's more traditional investigator-initiated grants. Its central goal is to back individual scientists who show exceptional creativity and who want to pursue bold, potentially transformative ideas aimed at major biomedical or behavioral challenges. NIH frames this as a "high-risk" program, meaning the work may be unconventional, speculative, or not yet supported by the kind of preliminary evidence typically expected in standard grant mechanisms, but it must still be compelling in terms of its potential impact.

A defining feature of this program is the requirement that the proposed research truly be "pioneering." In practice, NIH describes this as research that is substantially different from what is already being pursued in the applicant's own laboratory or by others in the field. The program is explicitly looking for big departures from an investigator's established line of work, rather than incremental extensions. Because the award is intended to support a major shift or leap in direction, awardees are also expected to devote the majority of their research effort to the project, with a stated minimum commitment of at least 51 percent of their research time focused on activities supported by the Pioneer Award.

From an administrative and funding standpoint, this opportunity uses the DP1 grant mechanism. NIH anticipated committing about $6 million total in fiscal year 2010, with the expectation of making at least seven awards, assuming enough applications were received that met the scientific and programmatic bar. The announcement makes clear that the number of awards depends on the quality and merit of the submissions rather than a fixed quota.

The opportunity is issued by NIH under Funding Opportunity Number RFA-RM-09-010, categorized as a discretionary grant in the health area, and associated with CFDA number 93.310 (Trans-NIH Research Support). There is no cost-sharing or matching requirement. Key dates listed for the announcement include a posted date of August 18, 2009, and an application closing date of October 20, 2009, with an archive date of November 20, 2009.

Eligibility is broad and includes many organization types across the public, private, nonprofit, and certain governmental sectors. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education; nonprofits with and without 501(c)(3) status (including those other than universities); state governments; federally recognized Native American tribal governments and other tribal organizations; U.S. territories or possessions; small businesses; and for-profit organizations (including those other than small businesses). The announcement also calls out additional eligible categories such as historically black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), faith-based or community-based organizations, regional organizations, and eligible federal agencies.

For applicants seeking the full official text and requirements, NIH provided an announcement link at http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-09-010.html. For technical issues accessing the announcement, the listed contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

2010 NIH Director's Pioneer Award Program (DP1) FAQs

What is the 2010 NIH Director's Pioneer Award Program (DP1)?

The 2010 NIH Director's Pioneer Award Program (DP1) is a National Institutes of Health (NIH) funding opportunity intended to complement (and not replace) NIH's traditional investigator-initiated grants. It is designed to support individual scientists with exceptional creativity who want to pursue bold, potentially transformative ideas addressing major biomedical or behavioral challenges.

What is the main goal of this funding opportunity?

The central goal is to back individual investigators proposing high-impact, potentially transformative research ideas. NIH describes the program as "high-risk," meaning projects may be unconventional or speculative and may not have the level of preliminary data usually expected in standard NIH grant mechanisms, as long as the potential impact is compelling.

What does NIH mean by "high-risk" in this program?

"High-risk" refers to research that may be unconventional, speculative, or not yet supported by typical preliminary evidence required for standard grants. The emphasis is on the potential for major impact rather than on extensive supporting data at the time of application.

What does it mean for the proposed research to be "pioneering"?

NIH expects proposed research to be truly "pioneering," meaning it should be substantially different from what is already being pursued in the applicant's own laboratory and from what others in the field are doing. The program is looking for major departures from established lines of work, not incremental extensions.

Is this program intended for incremental research extensions?

No. The announcement emphasizes that the program is explicitly looking for big departures from an investigator's established research direction rather than incremental, step-by-step extensions of existing work.

How much time must an awardee commit to the Pioneer Award project?

Awardees are expected to devote the majority of their research effort to the project. The stated minimum commitment is at least 51 percent of their research time focused on activities supported by the Pioneer Award.

What grant mechanism is used for this opportunity?

This opportunity uses the DP1 grant mechanism.

How much funding did NIH expect to commit for FY 2010?

NIH anticipated committing about $6 million total in fiscal year 2010 for this program.

How many awards did NIH expect to make?

NIH expected to make at least seven awards, assuming enough applications were received that met the scientific and programmatic bar.

Is the number of awards fixed?

No. The announcement indicates the number of awards depends on the quality and merit of submissions rather than a fixed quota.

What is the Funding Opportunity Number for this announcement?

The Funding Opportunity Number is RFA-RM-09-010.

How is this opportunity categorized?

It is categorized as a discretionary grant in the health area.

What CFDA number is associated with this program?

The opportunity is associated with CFDA number 93.310 (Trans-NIH Research Support).

Is cost sharing or matching required?

No. The announcement states there is no cost-sharing or matching requirement.

What are the key dates listed in the announcement?

The posted date is August 18, 2009. The application closing date is October 20, 2009. The archive date is November 20, 2009.

Who can apply (what organizations are eligible)?

Eligibility is broad and includes many organization types across public, private, nonprofit, and certain governmental sectors. Eligible applicants include:

  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • Nonprofits with 501(c)(3) status (including those other than universities)
  • Nonprofits without 501(c)(3) status (including those other than universities)
  • State governments
  • Federally recognized Native American tribal governments
  • Other Native American tribal organizations
  • U.S. territories or possessions
  • Small businesses
  • For-profit organizations (including those other than small businesses)

Are specific institution types explicitly mentioned as eligible?

Yes. The announcement also calls out additional eligible categories, including:

  • Historically Black Colleges and Universities (HBCUs)
  • Hispanic-serving institutions
  • Alaska Native and Native Hawaiian-serving institutions
  • Tribally Controlled Colleges and Universities (TCCUs)
  • Faith-based or community-based organizations
  • Regional organizations
  • Eligible federal agencies

Where can applicants find the official announcement and full requirements?

NIH provided the official announcement link here: http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-09-010.html

Who should be contacted for technical issues accessing the announcement?

For technical issues accessing the announcement, the listed contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

Does this program replace traditional NIH investigator-initiated grants?

No. NIH states the program is designed to sit alongside NIH's more traditional investigator-initiated grants, not replace them.

What kinds of challenges is the program aiming to address?

The program targets bold, potentially transformative ideas aimed at major biomedical or behavioral challenges.

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