Opportunity Information: Apply for RFA RM 13 006

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "2014 NIH Pioneer Award Program (DP1)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
  • This funding opportunity was created on Aug 8, 2013 and posted on Aug 8, 2013.
  • Applicants must submit their applications by Oct 9, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $5,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • The number of recipients for this funding is limited to 7 candidate(s).
  • Eligible applicants include: City or township governments For profit organizations other than small businesses Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Private institutions of higher education Public housing authorities/Indian housing authorities Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) County governments State governments Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The 2014 NIH Pioneer Award Program (DP1), offered by the National Institutes of Health (NIH), is a discretionary grant opportunity designed to sit alongside and strengthen NIH's traditional investigator-initiated funding mechanisms. Its core purpose is to identify and support individual scientists who show exceptional creativity and who are willing to pursue bold, high-risk ideas that could reshape understanding or practice across major areas of biomedical or behavioral research. The program is explicitly aimed at work that could be unusually high impact, meaning the proposed research is expected to have broad implications beyond a narrow niche and potentially influence a larger field, multiple fields, or a major scientific or public health challenge.

A defining feature of the Pioneer Award is the expectation that the project be genuinely "pioneering." In NIH terms, that means the research direction should be substantially different from what the investigator is already doing in their established research program, and it should also be meaningfully distinct from directions already being widely pursued by others. The emphasis is on potentially transforming approaches rather than incremental advances. In practical terms, applicants are expected to propose work that could open new scientific pathways, introduce unconventional frameworks or methods, or tackle difficult problems in ways that standard mechanisms may be less willing to support because of uncertainty or lack of extensive preliminary data.

This opportunity is listed under Funding Opportunity Number RFA-RM-13-006 (titled "2014 NIH Pioneer Award Program (DP1)") and falls within the health funding activity category. NIH anticipated making about 7 awards under this announcement, with an estimated total funding amount of $5,000,000. The award ceiling is listed as $500,000. The program does not require cost sharing or matching funds, which generally makes it more accessible for applicants who may not be able to commit institutional funds as a condition of eligibility.

Eligibility is broad across many types of U.S.-based organizations. Eligible applicants include public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities), small businesses, and for-profit organizations (other than small businesses), as well as a range of government entities such as state governments, county governments, city or township governments, independent school districts, special district governments, and public housing authorities/Indian housing authorities. The eligibility language also explicitly includes various mission-focused and minority-serving institutions and community-based organizations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations and eligible federal agencies. Regional organizations and U.S. territories or possessions are also included in the expanded eligibility list.

At the same time, there are important geographic restrictions. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. However, foreign components, as defined in the NIH Grants Policy Statement, are allowed, meaning a U.S. applicant organization may be able to include certain foreign activities or collaborations if they meet NIH's definition and policy requirements.

From a timing and administrative standpoint, the opportunity was posted and created on August 8, 2013. The original closing date and the current closing date are both listed as October 9, 2015, and the archive date is November 9, 2015. The CFDA number associated with this opportunity is 93.310 (Trans-NIH Research Support). Applicants or interested parties who need the full official details are directed to NIH's announcement page at http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-13-006.html, and technical access or linking issues are handled through the NIH Office of Extramural Research (OER) webmaster contact (FBOWebmaster@OD.NIH.GOV).

Overall, this program is best understood as an NIH mechanism intended to empower unusually creative scientists to pursue ambitious research that might be too novel, too cross-cutting, or too speculative for conventional funding routes, with the explicit goal of generating transformative advances in biomedical or behavioral science.

Frequently Asked Questions (FAQs): 2014 NIH Pioneer Award Program (DP1)

What is the 2014 NIH Pioneer Award Program (DP1)?

The 2014 NIH Pioneer Award Program (DP1) is a discretionary grant opportunity from the National Institutes of Health (NIH) designed to complement and strengthen NIH's traditional investigator-initiated funding. It focuses on supporting individual scientists with exceptional creativity who are willing to pursue bold, high-risk research ideas.

What is the main goal of the NIH Pioneer Award?

The main goal is to identify and support pioneering, high-risk, high-reward research that could reshape understanding or practice across major areas of biomedical or behavioral research, with the potential for unusually high impact beyond a narrow niche.

What kinds of research does NIH consider "pioneering" under this program?

NIH describes "pioneering" research as work that is substantially different from the investigator's established research program and meaningfully distinct from directions already being widely pursued by others. The intent is to support potentially transformative approaches rather than incremental advances.

Does the program prioritize high-risk ideas?

Yes. The opportunity explicitly aims to support bold, high-risk ideas, including work that may be too novel, cross-cutting, or speculative for conventional mechanisms, and that may not have extensive preliminary data.

What is the expected impact of projects funded through this award?

Projects are expected to have broad implications, potentially influencing a larger field, multiple fields, or a major scientific or public health challenge, rather than producing narrowly focused outcomes.

What is the funding opportunity number for this announcement?

The funding opportunity number is RFA-RM-13-006, titled "2014 NIH Pioneer Award Program (DP1)."

Which agency is offering this grant opportunity?

This opportunity is offered by the National Institutes of Health (NIH).

What is the funding activity category for this opportunity?

The opportunity is listed under the health funding activity category.

How many awards did NIH anticipate making under this announcement?

NIH anticipated making about 7 awards under this announcement.

What is the estimated total funding amount?

The estimated total funding amount is $5,000,000.

What is the award ceiling listed for this program?

The award ceiling is listed as $500,000.

Is cost sharing or matching required?

No. The program does not require cost sharing or matching funds.

Who is eligible to apply?

Eligibility is broad across many U.S.-based organizations, including public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), small businesses, and for-profit organizations (other than small businesses). Various government entities are also eligible, such as state, county, and city or township governments, independent school districts, special district governments, and public housing authorities/Indian housing authorities.

Are minority-serving and mission-focused institutions eligible?

Yes. The eligibility language explicitly includes institutions and organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). It also includes faith-based and community-based organizations.

Are U.S. territories or regional organizations included in eligibility?

Yes. The expanded eligibility list includes regional organizations and U.S. territories or possessions.

Are foreign (non-U.S.) organizations allowed to apply?

No. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply.

Can a U.S. organization apply if part of the work will be conducted outside the United States?

Non-domestic components of U.S. organizations are not eligible to apply. However, foreign components, as defined in the NIH Grants Policy Statement, are allowed, meaning a U.S. applicant organization may be able to include certain foreign activities or collaborations if they meet NIH's definition and policy requirements.

When was this opportunity posted and created?

The opportunity was posted and created on August 8, 2013.

What are the closing date and archive date listed for this opportunity?

The original closing date and the current closing date are both listed as October 9, 2015, and the archive date is November 9, 2015.

What is the CFDA number associated with this opportunity?

The CFDA number is 93.310 (Trans-NIH Research Support).

Where can applicants find the official funding announcement?

The official details are available on NIH's announcement page: http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-13-006.html.

Who should be contacted for technical access or linking issues related to the announcement page?

Technical access or linking issues are handled through the NIH Office of Extramural Research (OER) webmaster contact: FBOWebmaster@OD.NIH.GOV.

How does this program relate to NIH's traditional funding mechanisms?

The program is designed to sit alongside and strengthen traditional investigator-initiated NIH funding by empowering unusually creative scientists to pursue ambitious research directions that standard mechanisms may be less willing to support due to uncertainty or limited preliminary evidence.

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