Opportunity Information: Apply for RFA RM 14 011
Apply for RFA RM 14 011
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "4D Nucleome Network Data Coordination and Integration Center (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
- This funding opportunity was created on Sep 24, 2014 and posted on Sep 24, 2014.
- Applicants must submit their applications by Dec 16, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $2,500,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments County governments Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses City or township governments Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Small businesses Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Independent school districts Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The NIH opportunity RFA-RM-14-011 seeks a single awardee to run the Four Dimensional Nucleome (4DN) Network Data Coordination and Integration Center (DCIC) under a U01 cooperative agreement mechanism. The central goal of this center is to serve as the network-wide hub for data management and integration: it is expected to collect, store, curate, and present all datasets, associated metadata, and analysis tools produced across the 4DN Network. In practice, this means building and operating the infrastructure that turns many separate outputs from multiple projects into a unified, usable, and discoverable resource that supports both the immediate 4DN consortium and the broader research community.
A major emphasis of the FOA is not just warehousing files, but enabling consistent, high-quality, reusable science. The DCIC is expected to help develop, refine, and distribute common metadata frameworks and standards so that data generated by different labs, platforms, and experimental modalities can be compared and combined. This includes promoting community adoption of those standards beyond the 4DN Network itself. Alongside standards work, the DCIC is also expected to support integrative analysis approaches spanning a wide range of data types (reflecting the "4D nucleome" concept of genome organization across space and time). The FOA also highlights the need for visualization and analysis tools that make complex datasets understandable and accessible to non-expert users, indicating that user-facing interfaces and education-oriented design are important parts of the mission, not optional extras.
From an administrative standpoint, the program is a discretionary health-related funding opportunity offered by the National Institutes of Health. It uses the cooperative agreement model, which generally implies substantial NIH programmatic involvement during execution, closer coordination with NIH staff, and an expectation of active collaboration with the broader 4DN Network. The announcement anticipates one total award, with an estimated total funding level of $2,500,000 and an award ceiling of $2,500,000. There is no cost sharing or matching requirement specified.
Eligibility is broad across U.S.-based organizations and governmental entities. Eligible applicants include a wide range of domestic institutions such as public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and non-501(c)(3) nonprofits), for-profit organizations other than small businesses, and small businesses, as well as state, county, city/township, special district governments, independent school districts, and certain housing authorities. The FOA also explicitly includes various mission- or population-focused institution types as eligible (for example, HBCUs, Hispanic-serving institutions, AANAPISI institutions, tribally controlled colleges and universities, and Alaska Native and Native Hawaiian serving institutions), along with faith-based or community-based organizations and eligible federal agencies. At the same time, the opportunity restricts foreign involvement: non-U.S. entities (foreign organizations and foreign institutions) are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components as defined by NIH policy are not allowed.
Key timing details in the source information show the FOA was posted on September 24, 2014, with an original and current closing date of December 16, 2014, and an archive date of January 16, 2015. The CFDA number listed is 93.310 (Trans-NIH Research Support). The full announcement is referenced via the NIH Grants Guide link provided in the source, and NIH’s Office of Extramural Research webmaster contact is included for access or technical issues related to the posting.
Overall, this FOA is essentially about creating the core data backbone for the 4DN initiative: a centralized, standards-driven, user-accessible platform that not only preserves and displays what the network generates, but actively helps the network and the wider field make those outputs interoperable, integrable, and usable for discovery.
FAQs: NIH RFA-RM-14-011 (4DN Network Data Coordination and Integration Center)
What is NIH RFA-RM-14-011?
RFA-RM-14-011 is an NIH funding opportunity announcement (FOA) to support a single awardee that will operate the Four Dimensional Nucleome (4DN) Network Data Coordination and Integration Center (DCIC) under a U01 cooperative agreement.
What is being funded under this opportunity?
This FOA funds the creation and operation of the 4DN Network DCIC, which is intended to function as the network-wide hub for data management and data integration across the 4DN Network.
How many awards does NIH expect to make?
The announcement anticipates one total award (a single awardee).
What is the funding amount and award ceiling?
The estimated total funding level is $2,500,000, and the award ceiling is also $2,500,000.
Is cost sharing or matching required?
No cost sharing or matching requirement is specified in the provided information.
What mechanism will be used (grant type)?
The FOA uses a U01 cooperative agreement mechanism.
What does a U01 cooperative agreement imply for how the project will run?
Based on the provided description, the cooperative agreement model generally implies substantial NIH programmatic involvement during execution, closer coordination with NIH staff, and an expectation of active collaboration with the broader 4DN Network.
What is the central goal of the DCIC?
The central goal is to serve as the network-wide hub for data management and integration by collecting, storing, curating, and presenting all datasets, associated metadata, and analysis tools produced across the 4DN Network.
Is the DCIC expected to do more than store files?
Yes. A major emphasis is enabling consistent, high-quality, reusable science. The DCIC is expected to support standards, integration, and usability, not just warehousing files.
What kinds of data will the DCIC handle?
The DCIC is expected to handle all datasets generated across the 4DN Network, along with associated metadata and analysis tools produced by multiple projects.
What is the role of metadata standards in this FOA?
The DCIC is expected to help develop, refine, and distribute common metadata frameworks and standards so that data produced by different labs, platforms, and experimental modalities can be compared and combined.
Does the FOA emphasize adoption of standards beyond the 4DN Network?
Yes. The provided information notes that the DCIC should promote community adoption of those standards beyond the 4DN Network itself.
Is integrative analysis part of the DCIC responsibilities?
Yes. The DCIC is expected to support integrative analysis approaches spanning a wide range of data types, reflecting the "4D nucleome" concept of genome organization across space and time.
Are visualization and user-facing tools required?
Yes. The FOA highlights the need for visualization and analysis tools to make complex datasets understandable and accessible to non-expert users, indicating that user-facing interfaces and education-oriented design are important components.
Who will the DCIC serve?
The DCIC is intended to support both the immediate 4DN consortium and the broader research community by providing a unified, usable, and discoverable resource.
What is meant by the DCIC being a "network-wide hub"?
In practice, it means building and operating infrastructure that turns many separate outputs from multiple projects into a unified resource by managing data intake, storage, curation, presentation, and access to related tools and metadata.
What agency is offering this opportunity?
The opportunity is offered by the National Institutes of Health (NIH) as a discretionary health-related funding opportunity.
What is the CFDA number for this opportunity?
The CFDA number listed is 93.310 (Trans-NIH Research Support).
When was the FOA posted?
The FOA was posted on September 24, 2014.
What is the application closing date?
The original and current closing date shown is December 16, 2014.
When was the FOA archived?
The archive date shown is January 16, 2015.
Is this opportunity still open?
Based on the provided dates (closing date of December 16, 2014 and archive date of January 16, 2015), the opportunity is not open.
Which organizations are eligible to apply?
Eligibility is broad across U.S.-based organizations and governmental entities. The provided information includes: public and private institutions of higher education; nonprofit organizations (501(c)(3) and non-501(c)(3)); for-profit organizations other than small businesses; small businesses; and a range of government entities such as state, county, city/township, and special district governments, as well as independent school districts and certain housing authorities.
Are mission- or population-focused institutions eligible?
Yes. The FOA explicitly includes institution types such as HBCUs, Hispanic-serving institutions, AANAPISI institutions, tribally controlled colleges and universities, and Alaska Native and Native Hawaiian serving institutions.
Are faith-based or community-based organizations eligible?
Yes. The provided information states that faith-based or community-based organizations are eligible.
Are federal agencies eligible?
Yes. The provided information indicates eligible federal agencies are included as eligible applicants.
Are foreign organizations eligible to apply?
No. Non-U.S. entities (foreign organizations and foreign institutions) are not eligible to apply.
Can a U.S. organization apply if it has a non-U.S. component?
No. The provided information states that non-U.S. components of U.S. organizations are not eligible.
Are foreign components allowed under NIH policy for this FOA?
No. The provided information states that foreign components (as defined by NIH policy) are not allowed.
Where can applicants find the full announcement?
The full announcement is referenced via the NIH Grants Guide link provided in the source information.
Who is listed for technical or access issues related to the posting?
The provided information notes that NIH's Office of Extramural Research webmaster contact is included for access or technical issues related to the posting.
What is the overall purpose of this FOA in plain terms?
It is focused on creating the core data backbone for the 4DN initiative: a centralized, standards-driven, user-accessible platform that preserves, displays, and helps make the network's outputs interoperable, integrable, and usable for scientific discovery.
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