Opportunity Information: Apply for HRSA 26 052
Apply for HRSA 26 052
- The Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Sickle Cell Disease Regional Care Excellence (SoRCE) Program" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.365.
- This funding opportunity was created on 2026-06-05.
- Applicants must submit their applications by 2026-07-08. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $950,000.00 in funding.
- The number of recipients for this funding is limited to 7 candidate(s).
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.
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Opportunity Summary:
The Sickle Cell Disease Regional Care Excellence (SoRCE) Program is a federal funding opportunity from the Health Resources and Services Administration (HRSA) designed to improve health outcomes for people living with sickle cell disease (SCD) by expanding access to care, raising the quality and consistency of that care, and tracking quality-of-life indicators over time. The need is substantial: roughly 100,000 people in the United States have SCD, and while early, consistent treatment can prevent or lessen severe complications (including recurrent severe pain episodes, silent strokes, and early death), many patients still do not receive the care and therapies that are known to help. A major concern highlighted in the program description is that even though SCD is universally identified at birth through newborn screening, fewer than half of children with SCD receive the treatment they need. As patients move into adolescence and adulthood, gaps often widen, partly because of difficult transitions between pediatric and adult care systems and partly because clinicians outside specialized centers may still be getting up to speed on the newest disease-modifying therapies and how to identify appropriate candidates.
SoRCE is structured around seven geographic regions, with one award recipient selected per region to serve as a Regional Coordinating Hub (RCH). Each RCH is expected to function as the central organizer and convener for its region, building and managing partnerships across clinical providers and community-based organizations. The core operating approach is continuous quality improvement (CQI), meaning the hubs and their partners are expected to use ongoing measurement and iterative improvement methods to identify gaps in care, test solutions, and scale what works. In practical terms, this emphasis points to activities like improving referral pathways, increasing uptake of guideline-based services, strengthening coordination between primary care and specialty care, improving patient and family engagement, and making sure quality-of-life outcomes are tracked rather than focusing only on clinical encounters or acute events.
The award is offered as a cooperative agreement, which generally signals that HRSA will have substantial involvement in the work beyond simply providing funding. The funding opportunity number is HRSA 26 052, listed under CFDA 93.365, and it falls within the Health funding activity category. HRSA anticipates making seven awards total (one per region). The maximum award amount is $950,000 (award ceiling). The application closing date is July 8, 2026, and the opportunity was created on June 5, 2026.
Eligible applicants include a range of organizations that can credibly serve as regional conveners and operational leaders for SCD systems improvement, including public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities, excluding institutions of higher education in those nonprofit categories), and other eligible entity types as allowed by the announcement. The opportunity description also points toward care delivery organizations such as hospitals, clinics, and health centers as relevant participants, reflecting the program’s focus on building practical, region-wide networks that can improve access, care quality, and patient-reported or quality-of-life indicators across the lifespan for people living with SCD.
Frequently Asked Questions (FAQs) - Sickle Cell Disease Regional Care Excellence (SoRCE) Program (HRSA 26 052)
1) What is the Sickle Cell Disease Regional Care Excellence (SoRCE) Program?
The Sickle Cell Disease Regional Care Excellence (SoRCE) Program is a federal funding opportunity from the Health Resources and Services Administration (HRSA) intended to improve health outcomes for people living with sickle cell disease (SCD). The program focuses on expanding access to care, improving the quality and consistency of care across settings, and tracking quality-of-life indicators over time.
2) Which federal agency is offering this funding opportunity?
This opportunity is offered by the Health Resources and Services Administration (HRSA).
3) What problem or need is this program trying to address?
The program description highlights substantial need: roughly 100,000 people in the United States have SCD, and although early and consistent treatment can prevent or reduce severe complications, many patients still do not receive known effective care and therapies. A specific concern is that fewer than half of children with SCD receive the treatment they need, even though SCD is universally identified at birth through newborn screening. The description also notes gaps that can widen during adolescence and adulthood, including difficult transitions from pediatric to adult care and variability in clinician familiarity with newer disease-modifying therapies.
4) What are the main goals of SoRCE?
SoRCE is designed to:
- Expand access to care for people living with SCD
- Raise the quality and consistency of SCD care across a region
- Track quality-of-life indicators over time (not only clinical encounters or acute events)
5) How is the SoRCE Program organized geographically?
SoRCE is structured around seven geographic regions. HRSA anticipates selecting one award recipient per region.
6) How many total awards does HRSA expect to make under this opportunity?
HRSA anticipates making seven awards total, with one award per region.
7) What is a Regional Coordinating Hub (RCH)?
In each region, the award recipient will serve as a Regional Coordinating Hub (RCH). The RCH is expected to act as the central organizer and convener for the region, building and managing partnerships across clinical providers and community-based organizations to support regional improvement in SCD care.
8) What does it mean that the awardee serves as a "central organizer and convener"?
Based on the description provided, the RCH is expected to bring together partners across the region (including clinical providers and community-based organizations), coordinate efforts to improve care, and manage those partnerships so the region can identify gaps and implement improvements more consistently.
9) What core approach does the program expect RCHs and partners to use?
The program emphasizes continuous quality improvement (CQI). This means using ongoing measurement and iterative improvement methods to identify gaps in care, test solutions, and scale approaches that work.
10) What kinds of activities might be supported under the CQI focus described?
The description points to practical improvement activities such as:
- Improving referral pathways
- Increasing uptake of guideline-based services
- Strengthening coordination between primary care and specialty care
- Improving patient and family engagement
- Tracking quality-of-life outcomes over time
11) Does the program focus only on clinical encounters or acute events?
No. The opportunity description explicitly emphasizes tracking quality-of-life outcomes over time, rather than focusing only on clinical encounters or acute events.
12) Why does the opportunity highlight transitions from pediatric to adult care?
The description notes that gaps in care often widen as patients move into adolescence and adulthood. It attributes this, in part, to difficult transitions between pediatric and adult care systems.
13) Does the opportunity mention issues related to clinician awareness of newer SCD therapies?
Yes. The description notes that clinicians outside specialized centers may still be getting up to speed on newer disease-modifying therapies and how to identify appropriate candidates, which can contribute to gaps in care.
14) What type of award mechanism is used for SoRCE?
This opportunity is offered as a cooperative agreement.
15) What does it mean that the funding is a cooperative agreement?
A cooperative agreement generally signals that HRSA will have substantial involvement in the work beyond simply providing funding.
16) What is the maximum award amount (award ceiling)?
The maximum award amount listed is $950,000.
17) What is the funding opportunity number for this program?
The funding opportunity number is HRSA 26 052.
18) What is the CFDA number associated with this opportunity?
The opportunity is listed under CFDA 93.365.
19) What is the funding activity category?
The funding activity category listed is Health.
20) When was this opportunity created?
The opportunity was created on June 5, 2026.
21) What is the application closing date?
The application closing date is July 8, 2026.
22) Who is eligible to apply for the SoRCE award?
Eligible applicants include:
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Nonprofit organizations (including 501(c)(3) and non-501(c)(3) entities), excluding institutions of higher education in those nonprofit categories
- Other eligible entity types as allowed by the announcement
23) Are hospitals, clinics, and health centers eligible applicants?
The description points toward care delivery organizations such as hospitals, clinics, and health centers as relevant participants in the regional networks. The eligibility list provided focuses on institutions of higher education and nonprofit organizations (plus other eligible entity types as allowed by the announcement). Whether a specific hospital, clinic, or health center is eligible to apply would depend on how it fits within the eligible categories stated in the announcement.
24) What kinds of partners are RCHs expected to work with?
Each RCH is expected to build and manage partnerships across clinical providers and community-based organizations. The description also reflects participation by care delivery organizations such as hospitals, clinics, and health centers.
25) What population is intended to benefit from this program?
The program is intended to benefit people living with sickle cell disease across the lifespan, including children, adolescents, and adults.
26) What outcomes does the opportunity emphasize improving or tracking?
The description emphasizes improving access, quality, and consistency of care and tracking quality-of-life indicators over time.
27) What severe complications of SCD are mentioned as potentially preventable or reducible with early, consistent treatment?
The description cites severe complications including recurrent severe pain episodes, silent strokes, and early death.
28) Why does the opportunity mention newborn screening?
The opportunity highlights that SCD is universally identified at birth through newborn screening, yet fewer than half of children with SCD receive the treatment they need. This underscores the gap between early identification and consistent, effective care delivery.
29) What is the overall program strategy implied by the description?
The description suggests a regional systems-improvement strategy: select one hub per region to coordinate a network, use continuous quality improvement to find and fix gaps, strengthen coordination across providers and community partners, and measure outcomes over time including quality-of-life indicators.
30) Does HRSA plan to make more than one award per region?
No. The description states that there will be one award recipient selected per region to serve as the Regional Coordinating Hub, and HRSA anticipates seven awards total across seven regions.
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