Opportunity Information: Apply for RFA TS 10 001
Apply for RFA TS 10 001
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "A Prospective Birth Cohort Study Involving Environmental Uranium Exposure in the Navajo Nation (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.161 Health Program for Toxic Substances and Disease Registry.
- This funding opportunity was created on Mar 11, 2010 and posted on Mar 11, 2010.
- Applicants must submit their applications by May 10, 2010 Letter of Intent Receipt Date April 12, 2010 Application Submission Receipt Date May 10, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- Eligible Organizations Public nonprofit organizations Private nonprofit organizations For profit organizations Small, minority, and women owned businesses Universities Colleges Research institutions Hospitals Community based organizations Faith based organizations Federally recognized or state recognized American Indian/Alaska Native tribal governments American Indian/Alaska Native tribally designated organizations Alaska Native villages Urban Indian health organizations Tribal epidemiology centers State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) Political subdivisions of States (in consultation with States) A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If you are applying as a bona fide agent of a state or local government, you must provide a letter from the state or local government as documentation of your status. Attach this documentation behind the first page of your application form or for electronic applications, use a .pdf file and attach as Other Documents and label as appropriate. Failure to meet the stated eligibility criteria by the time of the application deadline will result in the return of the application without review
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Opportunity Summary:
The Centers for Disease Control and Prevention (CDC), through the Agency for Toxic Substances and Disease Registry (ATSDR) Health Program (CFDA 93.161), offered a discretionary funding opportunity titled "A Prospective Birth Cohort Study Involving Environmental Uranium Exposure in the Navajo Nation (U01)" under Funding Opportunity Number RFA-TS-10-001. The purpose of the announcement was to fund an investigator-initiated cooperative agreement (U01) to design and carry out an epidemiological study focused on Navajo mothers and their infants, specifically examining health conditions that may be associated with non-occupational exposure to uranium contamination stemming from historical uranium mining and milling activities on the Navajo Nation.
The core intent of the opportunity was to support a prospective birth cohort approach, meaning participants would be enrolled and followed forward over time, rather than relying only on past records. This design is commonly used to better understand how environmental exposures during pregnancy and early life relate to outcomes in newborns and infants, and it can allow more precise exposure assessment and outcome tracking than many retrospective designs. In this case, the emphasis was on environmental (non-workplace) uranium exposure in the community, reflecting concerns that legacy mining and milling operations left contamination pathways that could affect families through water, soil, dust, or other environmental media.
The funding mechanism was a cooperative agreement, which typically indicates substantial involvement by the federal agency during the project period compared with a standard research grant. While the announcement summary does not list the exact collaboration details, the U01 structure generally means CDC/ATSDR would expect active coordination on study design elements, data collection approaches, participant protections, and other implementation features to ensure the project aligns with public health objectives and meets scientific and ethical standards, particularly given the sensitivities of conducting research in tribal communities and among pregnant people and infants.
The opportunity anticipated a single award, with an estimated total funding amount of $1,000,000. No cost sharing or matching was required. The notice did not specify an award ceiling or floor (both listed as 0), which usually signals that applicants needed to refer to the full FOA for budget expectations and allowable cost guidance, but the total anticipated amount and single-award structure imply a focused, competitively selected project rather than a broad multi-site program.
Eligibility was intentionally broad and included public and private nonprofit organizations, for-profit organizations, small/minority/women-owned businesses, universities and colleges, research institutions, hospitals, community-based and faith-based organizations, and multiple government entities. Importantly, eligibility explicitly included federally or state recognized American Indian/Alaska Native tribal governments and tribally designated organizations, Alaska Native villages, Urban Indian health organizations, tribal epidemiology centers, and state and local governments (including U.S. territories and freely associated states as listed). The announcement also allowed applications from bona fide agents of state or local governments, but required formal documentation (a letter) proving that status, with the warning that failing to meet eligibility requirements by the deadline would result in the application being returned without review.
Key dates were set in spring 2010. The FOA was posted and created on March 11, 2010. A letter of intent was due April 12, 2010, and full applications were due May 10, 2010 (this was both the original and current closing date). The archive date was June 9, 2010, indicating the opportunity was time-limited and is now closed. Applicants needing help accessing the full announcement were directed to contact the CDC Procurement and Grants Office (PGO) TIMS support line at 770-488-2700 or by email at PGOTIM@cdc.gov.
In practical terms, this grant opportunity was designed to generate high-quality epidemiological evidence about whether and how legacy uranium contamination may be affecting maternal and infant health in Navajo communities, using a forward-looking cohort design that can link measured or estimated environmental exposure during pregnancy and early infancy to subsequent health outcomes. The single-award, cooperative-agreement format points to an intent to build one carefully coordinated study with strong scientific oversight and close partnership, rather than distributing funds across many smaller, unrelated projects.
Frequently Asked Questions (FAQs)
What is the name of this CDC/ATSDR funding opportunity?
The opportunity was titled "A Prospective Birth Cohort Study Involving Environmental Uranium Exposure in the Navajo Nation (U01)."
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number was RFA-TS-10-001.
Which agency offered this grant?
The Centers for Disease Control and Prevention (CDC), through the Agency for Toxic Substances and Disease Registry (ATSDR) Health Program, offered the opportunity.
What program or CFDA number is associated with this opportunity?
The opportunity was associated with the ATSDR Health Program (CFDA 93.161).
What was the main purpose of the announcement?
The purpose was to fund an investigator-initiated cooperative agreement to design and carry out an epidemiological study of Navajo mothers and their infants, focused on health conditions that may be associated with non-occupational exposure to uranium contamination linked to historical uranium mining and milling on the Navajo Nation.
What type of study was this opportunity meant to support?
It was intended to support a prospective birth cohort study, meaning participants would be enrolled and followed forward over time.
What does "prospective birth cohort" mean in this context?
It means pregnant participants (and then their infants) would be enrolled and monitored going forward, rather than relying only on historical records. This approach is often used to understand how exposures during pregnancy and early life relate to newborn and infant outcomes, with the potential for more direct exposure assessment and outcome tracking than retrospective designs.
What environmental exposure was the focus of the research?
The research focus was environmental (non-workplace) uranium exposure in the community, specifically exposure connected to legacy uranium mining and milling activities on the Navajo Nation.
Was the focus on occupational or non-occupational exposure?
The emphasis was on non-occupational (environmental, community) exposure rather than workplace exposure.
What kinds of contamination pathways were highlighted?
The summary described potential pathways from legacy mining and milling contamination that could affect families through environmental media such as water, soil, dust, or other routes.
What funding mechanism was used?
The mechanism was an investigator-initiated cooperative agreement (U01).
What does a U01 cooperative agreement typically imply?
A cooperative agreement typically implies substantial involvement by the federal agency during the project period compared with a standard research grant. The summary indicates that, under a U01 structure, CDC/ATSDR would generally expect active coordination on study design elements, data collection approaches, participant protections, and other implementation features.
How many awards were anticipated?
The opportunity anticipated a single award.
What was the estimated total funding amount?
The estimated total funding amount was $1,000,000.
Was cost sharing or matching required?
No cost sharing or matching was required.
Was there an award ceiling or floor listed?
The notice did not specify an award ceiling or floor (both were listed as 0). This typically means applicants needed to consult the full FOA for budget expectations and allowable cost guidance.
Who was eligible to apply?
Eligibility was broad and included public and private nonprofit organizations, for-profit organizations, small/minority/women-owned businesses, universities and colleges, research institutions, hospitals, community-based and faith-based organizations, and multiple government entities.
Were tribal governments and tribal organizations eligible?
Yes. Eligibility explicitly included federally or state recognized American Indian/Alaska Native tribal governments and tribally designated organizations, Alaska Native villages, Urban Indian health organizations, tribal epidemiology centers, and state and local governments.
Were U.S. territories or freely associated states included in eligibility?
Yes. The eligibility description included state and local governments, including U.S. territories and freely associated states as listed in the opportunity materials.
Could a bona fide agent of a state or local government apply?
Yes, applications from bona fide agents of state or local governments were allowed, but they required formal documentation (a letter) proving that status.
What happened if an applicant did not meet eligibility requirements by the deadline?
The announcement warned that failing to meet eligibility requirements by the deadline would result in the application being returned without review.
What were the key dates for this opportunity?
The FOA was posted/created on March 11, 2010. The letter of intent was due April 12, 2010. Full applications were due May 10, 2010 (also shown as the current closing date). The archive date was June 9, 2010.
Is this funding opportunity still open?
No. The archive date of June 9, 2010 indicates the opportunity was time-limited and is now closed.
Was a letter of intent required, and when was it due?
A letter of intent was part of the timeline and was due April 12, 2010.
When were full applications due?
Full applications were due May 10, 2010.
What kind of project was CDC/ATSDR trying to support overall?
The intent was to generate high-quality epidemiological evidence about whether and how legacy uranium contamination may affect maternal and infant health in Navajo communities, using a forward-looking cohort design that can link environmental exposure during pregnancy and early infancy to subsequent health outcomes.
Why did the opportunity emphasize a single award and a cooperative agreement?
Based on the summary, the single-award structure and cooperative-agreement format pointed to an intent to build one carefully coordinated study with strong scientific oversight and close partnership, rather than distributing funds across many smaller, unrelated projects.
Who could applicants contact for help accessing the full announcement?
Applicants needing help accessing the full announcement were directed to contact the CDC Procurement and Grants Office (PGO) TIMS support line at 770-488-2700 or by email at PGOTIM@cdc.gov.
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