Opportunity Information: Apply for PAR 16 234

  • The HHS-NIH11 in the education, health sector is offering a public funding opportunity titled "Accelerating the Pace of Drug Abuse Research Using Existing Data (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273, 93.279, 93.399,.
  • This funding opportunity was created on May 10, 2016 and posted on May 10, 2016.
  • Applicants must submit their applications by May 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for PAR 16 234

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Opportunity Summary:

The grant opportunity "Accelerating the Pace of Drug Abuse Research Using Existing Data (R01)" (Funding Opportunity Number PAR 16-234) is a discretionary NIH research grant designed to speed up progress in drug abuse and addiction research by funding projects that rely on analyzing data that already exist. Instead of supporting new, time-consuming primary data collection, the FOA focuses on innovative secondary analyses of social science, behavioral, administrative, clinical, and neuroimaging datasets. The central idea is to help researchers extract more value from public-use datasets and other extant community-based or clinical data sources, generating insights more quickly and cost-effectively than starting new cohorts or trials from scratch.

The scientific scope is broad and covers drug-using behaviors and related disorders across substances, explicitly including alcohol, tobacco, prescription drugs, and other drugs. Projects are expected to deepen understanding of both etiology and epidemiology, meaning they can address why drug use and related disorders develop (causes, mechanisms, risk pathways) and how they spread or vary across populations (patterns, prevalence, incidence, and disparities). The FOA also emphasizes studying trajectories over time, such as how substance use begins, escalates, remits, or recurs, and how those pathways relate to real-world consequences like morbidity and mortality. In addition, it highlights risk and resilience factors linked to the development of psychopathology, opening the door to research on co-occurring mental health conditions, developmental vulnerability, protective influences, and the interaction of individual, family, and community factors.

A major thematic area is prevention, including prevention of drug use and prevention of HIV, reflecting the close links between substance use, risk behaviors, and infectious disease outcomes. Another priority is health services utilization, which can include how people access prevention or treatment services, barriers to care, service quality, engagement and retention, and how systems deliver or fail to deliver effective interventions. The FOA is also oriented toward practical impact: it encourages analyses that can inform strategies to guide the development, testing, implementation, and delivery of high-quality, effective, and efficient services for prevention and treatment of drug abuse and HIV. In plain terms, the announcement is not only about describing problems; it is also about producing evidence that can improve programs, policies, and clinical or community practice.

The eligible applicant pool is wide, reflecting NIH norms for R01 funding. Eligible organizations include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other Native American tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education when specified in those categories); for-profit organizations other than small businesses; small businesses; and additional applicants as permitted under NIH eligibility rules referenced in the full announcement. This breadth makes the opportunity relevant to universities, research institutes, health systems, policy groups, and other organizations with the capacity to conduct advanced analyses of large datasets.

Administratively, this is an NIH grant mechanism (R01) under the U.S. Department of Health and Human Services, with activity categories tied to education and health. The opportunity lists CFDA numbers 93.273, 93.279, and 93.399, indicating its alignment with NIH program areas connected to drug abuse, related behavioral health research, and broader health research infrastructure. The posted and creation dates are May 10, 2016, and the final listed closing date for that cycle is May 7, 2019. The opportunity lists an award ceiling of $500,000, which signals an upper bound on expected budget levels under the specific terms of this FOA (applicants would still need to follow NIH budget guidance and the FOA instructions). The "ExpectedAwards" field is not populated in the provided text, so the number of anticipated awards is not specified here.

Overall, the FOA is aimed at researchers who can pose strong, policy- and practice-relevant questions about substance use and related outcomes, and answer them using sophisticated and creative approaches applied to existing datasets. Competitive projects under this announcement would typically show that the proposed data source is well-suited to the research question, that the analytic plan is rigorous and innovative, and that the findings could meaningfully advance understanding of substance use etiology, population patterns, prevention (including HIV prevention), and the performance of prevention and treatment services.

Frequently Asked Questions (FAQs)

What is the title of this grant opportunity?

The opportunity is titled "Accelerating the Pace of Drug Abuse Research Using Existing Data (R01)."

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number listed is PAR 16-234.

What type of grant mechanism is this?

This opportunity uses the NIH R01 research project grant mechanism.

What is the main purpose of this FOA?

The purpose is to speed up progress in drug abuse and addiction research by funding projects that analyze data that already exist, rather than supporting new and time-consuming primary data collection.

What kind of research approach does the FOA emphasize?

It emphasizes innovative secondary analyses of existing datasets, including public-use datasets and other extant community-based or clinical data sources.

Does this FOA support collecting new primary data?

The FOA is specifically oriented toward using existing data instead of supporting new primary data collection, with the goal of producing insights more quickly and cost-effectively.

What types of datasets are considered relevant under this FOA?

The FOA highlights social science, behavioral, administrative, clinical, and neuroimaging datasets as relevant sources for analysis.

What substances and substance-related topics are within scope?

The scope is broad and explicitly includes alcohol, tobacco, prescription drugs, and other drugs, along with drug-using behaviors and related disorders.

What does the FOA mean by addressing etiology and epidemiology?

Etiology refers to why drug use and related disorders develop (such as causes, mechanisms, and risk pathways). Epidemiology refers to how substance use and related outcomes vary across populations (such as patterns, prevalence, incidence, and disparities).

Are studies of substance use over time (trajectories) encouraged?

Yes. The FOA emphasizes trajectories over time, including how substance use begins, escalates, remits, or recurs, and how these pathways relate to real-world outcomes.

What kinds of outcomes or consequences are mentioned as relevant?

The FOA specifically points to real-world consequences such as morbidity and mortality.

Does this FOA support research on co-occurring mental health issues?

Yes. It highlights risk and resilience factors linked to the development of psychopathology, which supports research on co-occurring mental health conditions and related vulnerability or protective influences.

What kinds of risk and resilience factors can be studied?

The FOA mentions developmental vulnerability, protective influences, and interactions among individual, family, and community factors as areas that can be examined using existing datasets.

Is prevention research a priority area?

Yes. Prevention is a major thematic area, including prevention of drug use.

Is HIV prevention specifically included?

Yes. The FOA explicitly includes prevention of HIV as a priority, reflecting links between substance use, risk behaviors, and infectious disease outcomes.

Does the FOA include research on health services and systems?

Yes. Health services utilization is highlighted, including access to prevention or treatment services, barriers to care, service quality, engagement and retention, and system performance in delivering effective interventions.

Is the FOA focused only on describing problems, or also on practical impact?

It is oriented toward practical impact as well. It encourages analyses that can inform strategies for developing, testing, implementing, and delivering high-quality, effective, and efficient services for prevention and treatment of drug abuse and HIV.

Which organizations are eligible to apply?

The eligible applicant pool is broad and includes state, county, city, or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other Native American tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (as described); for-profit organizations other than small businesses; and small businesses, along with additional applicants permitted under NIH eligibility rules referenced in the full announcement.

Is this opportunity relevant only to universities?

No. Based on the listed eligibility categories, it can be relevant to a range of organizations such as universities, research institutes, health systems, policy groups, governments, nonprofits, and for-profit entities that can conduct advanced analyses of large datasets.

Which federal department and agency administer this grant?

It is an NIH grant under the U.S. Department of Health and Human Services.

What are the CFDA numbers associated with this FOA?

The opportunity lists CFDA numbers 93.273, 93.279, and 93.399.

What is the award ceiling listed for this opportunity?

The opportunity lists an award ceiling of $500,000.

Does the provided information specify how many awards will be made?

No. The "ExpectedAwards" field is not populated in the provided text, so the anticipated number of awards is not specified here.

When was this opportunity posted and created?

The posted date and creation date are both listed as May 10, 2016.

What is the final listed closing date for this cycle?

The final listed closing date for that cycle is May 7, 2019.

What characteristics would a competitive project typically demonstrate under this FOA?

Based on the description provided, competitive projects would typically show that the existing data source is well-suited to the research question, that the analytic plan is rigorous and innovative, and that the findings could meaningfully advance understanding of substance use etiology, population patterns, prevention (including HIV prevention), and the performance of prevention and treatment services.

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