Opportunity Information: Apply for PA 13 183

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Addressing Health Disparities in NIDDK Diseases (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Apr 5, 2013 and posted on Apr 5, 2013.
  • Applicants must submit their applications by May 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Small businesses Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Private institutions of higher education State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Special district governments Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Native American tribal governments (Federally recognized) Independent school districts.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The "Addressing Health Disparities in NIDDK Diseases (R01)" opportunity (Funding Opportunity Number PA-13-183) was a National Institutes of Health research grant announcement from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Its central goal was to support investigator-initiated research that improves understanding of why certain populations experience a higher burden of disease, worse outcomes, or reduced access to effective prevention and treatment in areas covered by NIDDKs mission. In practical terms, NIDDK was looking for projects that could explain the drivers of disparities and, importantly, develop and test interventions that can reduce or eliminate those disparities. The focus was not only on describing differences across groups, but on generating actionable evidence about causes and solutions.

This announcement used the NIH R01 mechanism, which is the standard multi-year research project grant designed to support a defined set of research aims. As an R01, it was intended for substantial, hypothesis-driven or well-justified research programs that might include observational studies, mechanistic studies, behavioral or community-engaged work, clinical research, or intervention development and testing, as long as the work clearly addressed health disparities within NIDDK-relevant diseases. The opportunity was categorized as discretionary funding and aligned with a Food and Nutrition and Health activity category, reflecting NIDDKs broad scope across metabolic, digestive, and kidney health.

The scientific areas encouraged under this announcement covered a wide range of high-priority diseases and conditions within NIDDKs portfolio. These included diabetes, obesity, and nutrition-related disorders; hepatitis C; gallbladder disease; Helicobacter pylori infection; sickle cell disease; kidney diseases; urologic diseases; hematologic diseases; and metabolic, gastrointestinal, hepatic, and renal complications associated with HIV infection. The common thread across these topics was an emphasis on disparities: research that clarifies why disproportionate rates, severity, complications, or mortality occur in specific populations, and research that tests strategies to close those gaps. The interventions of interest could reasonably span clinical care delivery, preventive approaches, culturally and linguistically tailored programs, changes to care pathways, multilevel interventions addressing social and structural barriers, or other evidence-based strategies that can be evaluated for effectiveness.

Eligibility under PA-13-183 was broad and intentionally inclusive, allowing applications from many types of organizations. Eligible applicants included small businesses; for-profit organizations (including those other than small businesses); nonprofit organizations with or without 501(c)(3) status; public and private institutions of higher education; and multiple levels of government such as state, county, city or township governments, special district governments, and independent school districts. Public housing authorities and Indian housing authorities were also eligible. The announcement also explicitly highlighted a wide set of additional eligible applicants often central to disparities-focused work, including faith-based and community-based organizations; Historically Black Colleges and Universities (HBCUs); Hispanic-serving Institutions; Tribally Controlled Colleges and Universities (TCCUs); Alaska Native and Native Hawaiian Serving Institutions; and Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs). Tribal entities were eligible, including federally recognized Native American tribal governments and other tribal organizations. Notably, non-U.S. entities and foreign institutions were eligible to apply, and foreign components of U.S. organizations were allowed as defined by NIH policy, which broadened opportunities for collaborations when disparities-related questions required international expertise, populations, or comparisons.

There was no cost sharing or matching requirement, which is typical for many NIH research grants and reduces barriers for applicants, particularly smaller organizations or community partners. The program was posted on April 5, 2013, and the original and final closing date listed was May 7, 2016, with an archive date of June 7, 2016, meaning the specific announcement is no longer active but remains available for reference.

For applicants at the time, the key takeaway would have been that NIDDK wanted rigorous, solution-oriented health disparities research tied directly to its disease mission areas, with the flexibility to bring together biomedical, clinical, behavioral, and community-engaged approaches. The official full announcement was hosted on the NIH grants site (PA-13-183), and the NIH Office of Extramural Research webmaster contact was provided for access or linking issues.

Frequently Asked Questions (FAQs): Addressing Health Disparities in NIDDK Diseases (R01) - PA-13-183

What is the "Addressing Health Disparities in NIDDK Diseases (R01)" opportunity?

It was a National Institutes of Health (NIH) research grant announcement from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The Funding Opportunity Number was PA-13-183, and it supported investigator-initiated research focused on health disparities in diseases within NIDDK's mission.

What was the central goal of PA-13-183?

The goal was to support research that improves understanding of why certain populations experience a higher burden of disease, worse outcomes, or reduced access to effective prevention and treatment for NIDDK-relevant conditions. A major emphasis was on developing and testing interventions to reduce or eliminate those disparities, not only describing differences across groups.

What does it mean that this was an "R01" opportunity?

This announcement used the NIH R01 mechanism, NIH's standard multi-year research project grant for a defined set of research aims. It was intended for substantial, hypothesis-driven or well-justified research programs addressing health disparities in NIDDK-relevant diseases.

What kinds of research approaches were considered responsive?

The announcement was designed to be flexible and could include observational studies, mechanistic studies, behavioral or community-engaged work, clinical research, or intervention development and testing, as long as the work clearly addressed health disparities within diseases and conditions covered by NIDDK.

Was the focus only on documenting health differences between groups?

No. The emphasis was on generating actionable evidence about both causes and solutions, including research that explains drivers of disparities and develops and evaluates interventions to close gaps in outcomes, complications, or access to prevention and treatment.

What types of interventions were of interest under this announcement?

Interventions could span clinical care delivery, preventive approaches, culturally and linguistically tailored programs, changes to care pathways, multilevel interventions addressing social and structural barriers, and other evidence-based strategies that could be evaluated for effectiveness in reducing disparities.

Which diseases and conditions were included in the NIDDK mission areas highlighted by PA-13-183?

The encouraged scientific areas included diabetes, obesity, and nutrition-related disorders; hepatitis C; gallbladder disease; Helicobacter pylori infection; sickle cell disease; kidney diseases; urologic diseases; hematologic diseases; and metabolic, gastrointestinal, hepatic, and renal complications associated with HIV infection.

What was the common theme across the encouraged topic areas?

All topic areas were connected by a focus on disparities: research aimed at clarifying why disproportionate rates, severity, complications, or mortality occur in specific populations, and research that tests strategies to reduce or eliminate those disparities.

Was this considered discretionary funding?

Yes. The opportunity was categorized as discretionary funding and aligned with a Food and Nutrition and Health activity category, consistent with NIDDK's broad scope across metabolic, digestive, and kidney health.

Who was eligible to apply?

Eligibility was broad and included small businesses; for-profit organizations (including those other than small businesses); nonprofit organizations with or without 501(c)(3) status; public and private institutions of higher education; and various levels of government (state, county, city or township, special district governments, and independent school districts).

Were public housing authorities eligible?

Yes. Public housing authorities and Indian housing authorities were explicitly listed as eligible applicants.

Were community-based and faith-based organizations eligible to apply?

Yes. The announcement explicitly highlighted eligibility for faith-based and community-based organizations, which are often central partners in disparities-focused research and intervention work.

Were minority-serving institutions specifically identified as eligible?

Yes. The announcement highlighted Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs) as eligible applicants.

Were Tribal entities eligible to apply?

Yes. Eligible applicants included federally recognized Native American tribal governments and other tribal organizations.

Could non-U.S. or foreign institutions apply?

Yes. Non-U.S. entities and foreign institutions were eligible to apply. In addition, foreign components of U.S. organizations were allowed as defined by NIH policy, enabling international collaborations where appropriate to the disparities questions being studied.

Was there a cost sharing or matching requirement?

No. The announcement stated there was no cost sharing or matching requirement, which is typical for many NIH research grants.

When was PA-13-183 posted and when did it close?

The program was posted on April 5, 2013. The original and final closing date listed was May 7, 2016, and the archive date was June 7, 2016.

Is PA-13-183 still an active funding opportunity?

No. Based on the listed closing and archive dates, the specific announcement is no longer active and remains available for reference.

Where was the official full announcement hosted?

The official full announcement was hosted on the NIH grants site under PA-13-183.

Who was listed as a contact for access or linking issues?

The NIH Office of Extramural Research webmaster contact was provided for access or linking issues related to the official posting.

What was the main takeaway for applicants considering this opportunity?

NIDDK was seeking rigorous, solution-oriented health disparities research directly tied to NIDDK disease mission areas, with flexibility to integrate biomedical, clinical, behavioral, and community-engaged approaches, and with a strong emphasis on developing and testing interventions that could reduce or eliminate disparities.

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