Opportunity Information: Apply for CDC RFA PS10 10175
Apply for CDC RFA PS10 10175
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Addressing Syndemics Through Program Collaboration and Service Integration (PCSI)" and is now available to receive applicants.
- This funding opportunity was created on Apr 26, 2010 and posted on Apr 15, 2010.
- Applicants must submit their applications by Jun 15, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $5,400,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $400,000.00 in funding.
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- Eligible applicants that can apply for this funding opportunity are listed below State and local governments or their Bona Fide Agents A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a letter from the state or local government as documentation of the status is required. Attach with Other Attachment Forms when submitting via www.grants.gov. Eligible Jurisdictions Eligibility is limited to health departments or their bona fide agents in jurisdictions with at least 630 estimated AIDS cases, 225 estimated TB cases, 900 estimated syphilis cases, 6,760 estimated gonorrhea cases, and 82 estimated HBV cases. Applications may be submitted by health departments of states or CDC directly funded cities that meet the criterion above. This FOA is limited to jurisdictions with at least 630 estimated AIDS cases, 225 estimated TB cases, 900 estimated syphilis cases, 6,760 estimated gonorrhea cases, and 82 estimated HBV cases, because this will allow it to reach those areas with the greatest need for a syndemic approach to prevention to populations with multiple related risk that are disproportionately affected by multiple infections. The jurisdictions that meet this criterion account for 80 of the disease burden for AIDS, TB, Viral Hepatitis B, Syphilis, and Gonorrhea in the United States in 2007. Eligibility is limited to these applicants because this program was conceptualized and designed specifically for implementation by health departments whose populations represent high burden of disease across multiple diseases. Health departments have the necessary infrastructure in place and the legal authority to perform the required activities outlined in this funding announcement such as changing and implementing health policies, procedures, and systems impacting program collaboration and service integration (PCSI). These jurisdictions have been historically funded to provide categorical prevention programs for HIV, STD, viral hepatitis, and TB prevention services and thus have developed a robust infrastructure (e.g. organization structure, financial management systems, staff capacity, procurement and grant systems, etc.) capable of supporting this cross cutting initiative. In addition, laws and regulations have been put into place to enable health departments to perform certain activities to the exclusion of other entities in the interest of protecting the public and the public s health. A final reason is that limited and dwindling resources for core program activities make integration of prevention activities and efficiency in service delivery in these high burden jurisdictions critically important.
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Opportunity Summary:
The Addressing Syndemics Through Program Collaboration and Service Integration (PCSI) grant opportunity (CDC RFA PS10-10175) was a CDC discretionary cooperative agreement designed to help high-burden jurisdictions move beyond siloed, disease-specific public health programs and instead plan, expand, and support an integrated "syndemic" approach to preventing and controlling HIV/AIDS, viral hepatitis (with specific emphasis on hepatitis B in the eligibility burden criteria), sexually transmitted diseases (STDs), and tuberculosis (TB). The opportunity is rooted in the National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) strategy outlined in its white paper, "Enhancing the Prevention and Control of HIV/AIDS, viral hepatitis, STDs, and TB in the United States," which promotes program collaboration and service integration as a way to address overlapping epidemics that share risk factors, affected communities, and service delivery systems.
At its core, the program recognized that these infections often cluster in the same populations and are influenced by interconnected social and behavioral determinants, meaning that tackling them separately can miss key opportunities to prevent transmission and improve health outcomes. The grant therefore aimed to strengthen collaboration across traditionally categorical programs and to build practical, integrated service delivery models. Rather than funding isolated activities for a single disease program, the intent was to support approaches that coordinate policies, workflows, and services so that people can more easily receive multiple prevention and care services in one setting or through tightly coordinated systems.
The opportunity emphasized several intended benefits of PCSI. One major goal was to increase service efficiency by reducing duplication and fragmentation across programs, allowing health departments and their partners to do more with limited resources. Another goal was to maximize prevention impact by creating more chances to screen, test, treat, or vaccinate people who need services. In practice, that could mean aligning testing and referral processes, bundling prevention services, or ensuring that someone who comes in for one service (for example, an STD visit) is also assessed for HIV testing needs, hepatitis vaccination, or TB screening where appropriate. The program also aimed to improve health outcomes in communities disproportionately affected by multiple infections, acknowledging that the same groups often face overlapping burdens. In addition, it sought to improve public health operations by encouraging the use of shared data and more interoperable information practices, making it easier to coordinate across programs, monitor trends, and respond faster to changes in epidemiology and evolving technologies. Finally, it explicitly called for identifying ways to leverage and align resources to improve the yield and long-term sustainability of integrated services, an important focus given declining or constrained funding for core public health functions.
This funding opportunity was structured as a cooperative agreement, signaling that CDC anticipated substantial involvement with awardees beyond a typical grant relationship. While the announcement text provided here does not list specific required activities in detail, the cooperative agreement mechanism and the repeated emphasis on planning, scaling up, and implementation suggest that jurisdictions were expected to develop and operationalize integration strategies, not just explore them conceptually. The program was also framed as a way to help service providers adapt to shifting disease patterns and new tools, which implies a focus on building flexible systems rather than one-time projects.
Eligibility was intentionally narrow and targeted. Applicants had to be state or local health departments, or bona fide agents of those governments (with documentation required to confirm that status). Eligibility was further limited to jurisdictions meeting specific high-burden thresholds across multiple diseases: at least 630 estimated AIDS cases, 225 estimated TB cases, 900 estimated syphilis cases, 6,760 estimated gonorrhea cases, and 82 estimated hepatitis B cases. CDC justified this restriction by explaining that these jurisdictions represented the greatest need for syndemic prevention due to overlapping high burdens, and that the jurisdictions meeting the criteria accounted for about 80 percent of the national burden for those conditions in 2007. The announcement also explained why health departments were the intended implementers: they typically have the legal authority and established infrastructure to change and implement policies and systems, manage public funds, run population-level prevention programs, and coordinate activities that cut across multiple categorical programs.
In terms of funding size and scale, CDC expected to make six awards, with an estimated total funding amount of $5.4 million. Individual awards were expected to fall between $300,000 (floor) and $400,000 (ceiling), and there was no cost-sharing or matching requirement. The opportunity was posted on April 15, 2010, with an application closing date of June 15, 2010, and it was archived July 15, 2010. The administering agency was the Centers for Disease Control and Prevention, and applicants needing assistance accessing the full announcement were directed to the CDC Procurement and Grants Office technical support contact.
Overall, this grant opportunity was built to accelerate real-world integration of prevention and control efforts for HIV, viral hepatitis, STDs, and TB in the places facing the heaviest combined burdens. It positioned PCSI as both a practical operational strategy and a public health impact strategy: improving how health departments run programs, how data and systems support decision-making, and how communities experience services by making prevention and related care more connected, efficient, and responsive.
Frequently Asked Questions (FAQs)
What is the Addressing Syndemics Through Program Collaboration and Service Integration (PCSI) grant opportunity?
PCSI (CDC RFA PS10-10175) was a CDC discretionary cooperative agreement designed to help high-burden jurisdictions move beyond siloed, disease-specific programs and instead plan, expand, and support integrated approaches to preventing and controlling multiple, overlapping infections.
Which diseases and conditions were included in the PCSI “syndemic” focus?
The opportunity focused on HIV/AIDS, viral hepatitis (with specific emphasis on hepatitis B in the eligibility burden criteria), sexually transmitted diseases (STDs), and tuberculosis (TB).
What does “syndemic approach” mean in the context of this funding opportunity?
In this context, a syndemic approach recognizes that these infections often cluster in the same populations and are shaped by interconnected social and behavioral determinants. The grant emphasized coordinating policies, workflows, and services so people can access multiple prevention and care services in a more connected way rather than through separate, categorical programs.
What is meant by Program Collaboration and Service Integration (PCSI)?
PCSI refers to intentional collaboration across traditionally categorical public health programs and the creation of practical, integrated service delivery models. The intent was to reduce fragmentation and duplication by aligning processes and services across HIV, viral hepatitis, STD, and TB prevention and control efforts.
What was the main purpose of this CDC cooperative agreement?
The main purpose was to strengthen collaboration across disease programs and build operational, integrated service models that improve prevention impact, increase efficiency, and improve community health outcomes in places with the highest combined burdens.
How was this opportunity different from a typical single-disease grant?
Rather than funding isolated activities focused on one disease area, PCSI aimed to support approaches that coordinate policies, workflows, and service delivery across multiple programs so people can more easily receive multiple services in one setting or through closely coordinated systems.
What kinds of integration examples were implied by the announcement?
Examples included aligning testing and referral processes, bundling prevention services, and ensuring that someone seeking one service (such as an STD visit) is also assessed for HIV testing needs, hepatitis vaccination, or TB screening when appropriate.
What benefits did CDC intend PCSI to produce?
The opportunity emphasized several intended benefits: improved service efficiency by reducing duplication and fragmentation; maximized prevention impact by creating more chances to screen, test, treat, or vaccinate; improved health outcomes in communities disproportionately affected by multiple infections; improved public health operations through shared data and more interoperable information practices; and better alignment and leveraging of resources to support sustainability.
Why did CDC emphasize collaboration across categorical programs?
CDC noted that these epidemics share risk factors, affected communities, and service delivery systems. Addressing them separately can miss opportunities to prevent transmission and improve outcomes, while integrated approaches can make prevention and related services more connected and responsive.
Was this funding opportunity a grant or a cooperative agreement?
It was structured as a cooperative agreement, meaning CDC anticipated substantial involvement with awardees beyond a typical grant relationship.
What did the cooperative agreement structure suggest about expected work?
Based on the cooperative agreement mechanism and the emphasis on planning, scaling up, and implementation, jurisdictions were expected to develop and operationalize integration strategies rather than only explore them conceptually.
Who was eligible to apply?
Eligibility was limited to state or local health departments, or bona fide agents of those governments. Documentation was required to confirm bona fide agent status where applicable.
How was “high-burden” eligibility defined for this opportunity?
Applicants had to meet specific estimated burden thresholds across multiple conditions: at least 630 estimated AIDS cases, 225 estimated TB cases, 900 estimated syphilis cases, 6,760 estimated gonorrhea cases, and 82 estimated hepatitis B cases.
Why was eligibility restricted to a narrow set of jurisdictions?
CDC justified the restriction by stating that eligible jurisdictions represented the greatest need for syndemic prevention due to overlapping high burdens and that jurisdictions meeting the criteria accounted for about 80 percent of the national burden for those conditions in 2007.
Why were health departments the intended implementers?
The announcement explained that health departments typically have the legal authority and infrastructure to implement policies and systems, manage public funds, run population-level prevention programs, and coordinate activities across multiple categorical programs.
How many awards did CDC expect to make?
CDC expected to make six awards.
What was the estimated total funding amount?
The estimated total funding amount was $5.4 million.
What was the expected funding range for individual awards?
Individual awards were expected to range from $300,000 (floor) to $400,000 (ceiling).
Was cost-sharing or matching required?
No. The opportunity stated there was no cost-sharing or matching requirement.
When was the opportunity posted and when did applications close?
It was posted on April 15, 2010, and the application closing date was June 15, 2010.
When was this opportunity archived?
The opportunity was archived on July 15, 2010.
Which federal agency administered the opportunity?
The administering agency was the Centers for Disease Control and Prevention (CDC).
What CDC strategy or framework did the opportunity cite?
The opportunity was rooted in the National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) strategy described in the white paper titled “Enhancing the Prevention and Control of HIV/AIDS, viral hepatitis, STDs, and TB in the United States,” which promotes program collaboration and service integration.
Did the announcement emphasize data or information systems?
Yes. It emphasized improving public health operations through shared data and more interoperable information practices to support coordination, trend monitoring, and faster response to changes in epidemiology and evolving technologies.
Did the opportunity address sustainability?
Yes. It explicitly called for identifying ways to leverage and align resources to improve the yield and long-term sustainability of integrated services, particularly in the context of declining or constrained funding for core public health functions.
What kind of system change did PCSI appear to encourage?
It encouraged jurisdictions to build flexible, integrated systems that can adapt to shifting disease patterns and new tools, rather than relying on one-time or isolated projects.
Where were applicants directed if they needed help accessing the full announcement?
Applicants needing assistance accessing the full announcement were directed to the CDC Procurement and Grants Office technical support contact.
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