Opportunity Information: Apply for RFA DK 10 004
Apply for RFA DK 10 004
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Adherence Studies in Adolescents with Chronic Kidney or Urologic Diseases, or Diabetes (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Mar 10, 2010 and posted on Mar 10, 2010.
- Applicants must submit their applications by Nov 15, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: Independent school districts Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) State governments County governments City or township governments Special district governments Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Native American tribal governments (Federally recognized) For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Adherence Studies in Adolescents with Chronic Kidney or Urologic Diseases, or Diabetes (R01) funding opportunity (RFA-DK-10-004) is a National Institutes of Health grant announcement led by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) focused on improving treatment adherence among adolescents living with chronic kidney disease, urologic conditions, or diabetes. The core idea behind the opportunity is that adherence to prescribed regimens, whether that means taking medications correctly, using medical devices as directed, following dietary or fluid recommendations, or keeping up with required health behaviors, has a direct and often profound effect on health outcomes. Poor adherence in these diseases can increase complications, worsen long-term morbidity, and in severe cases contribute to preventable mortality. The opportunity highlights adolescence as a uniquely high-risk window for nonadherence because of developmental changes, shifting independence, competing school and social demands, and the broader transition toward adult responsibility for health management. It also notes a gap in the pediatric research landscape, pointing out that outside of HIV-related work there have historically been relatively few pediatric adherence studies, creating a need for more targeted research in these populations.
The purpose of the announcement is to support research projects that both deepen understanding and lead to practical improvements in adherence for this vulnerable age group. NIDDK is looking for studies that examine the factors influencing adherence, which can include individual, family, social, health system, and developmental drivers; develop and refine methods to measure adherence more appropriately and accurately in adolescents; and test new or improved strategies designed to enhance adherence. In practical terms, this can encompass observational and mechanistic research that identifies why adherence breaks down, measurement-focused work that improves how adherence is assessed (including objective, validated, and clinically meaningful measures), and intervention research that evaluates innovative ways to increase adherence and sustain it over time.
The mechanism used is the NIH Research Project Grant (R01), meaning applications are expected to propose a well-developed, hypothesis-driven or clearly justified research plan suitable for a standard multi-year NIH project. The announcement anticipated up to approximately $2,000,000 in total NIDDK funding in fiscal year 2011 to support up to six new awards, with an indicated award ceiling of $500,000. There is no cost sharing or matching requirement listed, which aligns with typical NIH R01 expectations.
Eligibility for applicants is broad and includes many types of U.S. and non-U.S. organizations. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, other than institutions of higher education), for-profit organizations (including small businesses and other for-profits), and multiple levels of government such as state, county, city or township, special district governments, and certain tribal governments and tribal organizations. The eligibility list also explicitly includes a range of mission-focused institutions and community-serving entities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, U.S. territories or possessions, regional organizations, and non-domestic (foreign) entities. The announcement is categorized as a discretionary grant opportunity and is associated with CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).
Key dates show the funding opportunity was posted and created on March 10, 2010, with an original and current closing date of November 15, 2010, and an archive date of December 16, 2010. While the opportunity itself is archived (meaning the specific competition has closed), the summary provides a clear picture of what NIDDK was seeking: rigorous research that can move the field beyond recognizing that adherence is a problem and toward understanding it, measuring it correctly, and implementing strategies that measurably improve adherence outcomes for adolescents managing chronic kidney or urologic diseases or diabetes.
Frequently Asked Questions (FAQs)
What is the funding opportunity RFA-DK-10-004 about?
RFA-DK-10-004, titled "Adherence Studies in Adolescents with Chronic Kidney or Urologic Diseases, or Diabetes (R01)," is an NIH grant announcement led by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It focuses on research to better understand, measure, and improve treatment adherence among adolescents living with chronic kidney disease, urologic conditions, or diabetes.
Which NIH institute is leading this opportunity?
The opportunity is led by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a component of the National Institutes of Health (NIH).
Why is treatment adherence the focus of this opportunity?
The announcement emphasizes that adherence to prescribed regimens (such as taking medications correctly, using medical devices as directed, following dietary or fluid recommendations, and maintaining required health behaviors) directly affects health outcomes. Poor adherence in the targeted diseases can increase complications, worsen long-term morbidity, and in severe cases contribute to preventable mortality.
Why does the opportunity emphasize adolescents?
Adolescence is described as a uniquely high-risk period for nonadherence due to developmental changes, increasing independence, competing school and social demands, and the transition toward greater personal responsibility for health management.
Which health conditions and patient populations are included?
The funding opportunity targets adolescents with chronic kidney disease, urologic diseases/conditions, or diabetes.
What kinds of adherence behaviors are included under this announcement?
The opportunity frames adherence broadly, including taking medications as prescribed, correctly using medical devices, following dietary and fluid recommendations, and keeping up with required health behaviors associated with managing chronic disease.
What is the main purpose of the research supported by this announcement?
The purpose is to support research projects that both deepen understanding and lead to practical improvements in adherence among adolescents with the targeted conditions.
What research topics does NIDDK want applicants to address?
The announcement highlights interest in studies that: (1) examine factors influencing adherence (individual, family, social, health system, and developmental drivers); (2) develop and refine methods to measure adherence appropriately and accurately in adolescents; and (3) test new or improved strategies designed to enhance adherence and sustain it over time.
Are observational or mechanistic studies allowed, or is this only for interventions?
Based on the description, the opportunity encompasses observational and mechanistic research that identifies why adherence breaks down, measurement-focused work that improves how adherence is assessed, and intervention research that evaluates innovative ways to increase adherence and sustain it.
Does the opportunity mention improving how adherence is measured?
Yes. A specific emphasis is placed on developing and refining adherence measurement methods, including objective, validated, and clinically meaningful measures tailored to adolescents.
What grant mechanism is used for this opportunity?
The mechanism is the NIH Research Project Grant (R01).
What does it mean that this is an R01?
In this announcement, an R01 is described as requiring a well-developed, hypothesis-driven (or clearly justified) research plan suitable for a standard multi-year NIH project.
How much total funding was anticipated for this opportunity?
The announcement anticipated up to approximately $2,000,000 in total NIDDK funding in fiscal year 2011.
How many awards were expected?
Up to six new awards were anticipated.
Was there an award ceiling mentioned?
Yes. The announcement indicated an award ceiling of $500,000.
Is cost sharing or matching required?
No cost sharing or matching requirement is listed in the provided summary, consistent with typical NIH R01 expectations.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S. and non-U.S. organizations, including: public and private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status, other than institutions of higher education); for-profit organizations (including small businesses and other for-profits); and multiple levels of government (state, county, city or township, special district governments), as well as certain tribal governments and tribal organizations.
Are minority-serving institutions and community-based organizations included in eligibility?
Yes. The eligibility list explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based and community-based organizations.
Are U.S. territories or regional organizations eligible?
Yes. The eligibility list includes U.S. territories or possessions and regional organizations.
Are foreign (non-U.S.) entities eligible to apply?
Yes. The eligibility list includes non-domestic (foreign) entities.
How is this opportunity categorized?
It is categorized as a discretionary grant opportunity.
What is the CFDA number associated with this opportunity?
The opportunity is associated with CFDA number 93.847, "Diabetes, Digestive, and Kidney Diseases Extramural Research."
When was the opportunity posted and created?
The opportunity was posted and created on March 10, 2010.
What was the application closing date?
The original and current closing date listed is November 15, 2010.
Is this funding opportunity still open?
No. The opportunity is archived. The archive date is December 16, 2010, and the closing date was November 15, 2010.
What is the practical takeaway from the archived summary?
Even though the specific competition is closed, the summary makes clear that NIDDK was seeking rigorous research that moves beyond recognizing adherence as a problem and toward understanding adherence drivers, measuring adherence accurately, and implementing strategies that measurably improve adherence outcomes for adolescents with chronic kidney or urologic diseases or diabetes.
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| Mouse Metabolic Phenotyping Centers Consortium (U24) Apply for RFA DK 10 006 Funding Number: RFA DK 10 006 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $600,000 |
| Coordinating and Bioinformatics Unit for the Mouse Metabolic Phenotyping Centers and the Diabetic Complications Consortium (U24) Apply for RFA DK 10 007 Funding Number: RFA DK 10 007 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $250,000 |
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| Type I Diabetes Impact Award (DP3) Apply for RFA DK 10 012 Funding Number: RFA DK 10 012 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Collaborative Studies on The Central Nervous System and Glycemia (R01) Apply for PAS 11 029 Funding Number: PAS 11 029 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| NIDDK Program Project Applications (P01) Apply for PAR 11 043 Funding Number: PAR 11 043 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Optimizing Recovery and Preservation of Endogenous Insulin Secretion in Individuals with Prediabetes or Recent Onset of Type 2 Diabetes (U01) Apply for RFA DK 10 013 Funding Number: RFA DK 10 013 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Lifestyle Interventions in Overweight and Obese Pregnant Women Consortium Research Coordinating Unit (RCU) (U01) Apply for RFA DK 10 015 Funding Number: RFA DK 10 015 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| A GenitoUrinary Development Molecular Anatomy Project (GUDMAP) (U01) Apply for RFA DK 11 001 Funding Number: RFA DK 11 001 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $100,000 |
| Limited Competition for the Continuation of Teen Longitudinal Assessment of Bariatric Surgery (Teen LABS) (UM1) Apply for RFA DK 10 503 Funding Number: RFA DK 10 503 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Fostering the Development of Interdisciplinary Team Science for the Study of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) (R24) Apply for RFA DK 10 016 Funding Number: RFA DK 10 016 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $350,000 |
| NIDDK Consortium Interconnectivity Network Coordinating Unit (dkCOIN CU) U24 Apply for RFA DK 11 005 Funding Number: RFA DK 11 005 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
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| Silvio O Conte Digestive Diseases Research Core Centers (P30) Apply for RFA DK 11 003 Funding Number: RFA DK 11 003 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
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