Opportunity Information: Apply for RFA DK 15 017
Apply for RFA DK 15 017
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Adherence Studies in Adolescents with Chronic Kidney or Urologic Diseases (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Jun 5, 2015 and posted on Jun 5, 2015.
- Applicants must submit their applications by Nov 2, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,330,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $450,000.00 in funding.
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) City or township governments Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) County governments Special district governments For profit organizations other than small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The grant opportunity titled "Adherence Studies in Adolescents with Chronic Kidney or Urologic Diseases (R01)" (Funding Opportunity Number RFA-DK-15-017) is a National Institutes of Health (NIH) research funding announcement focused on a specific and persistent problem in pediatric chronic disease care: adolescents often struggle to follow demanding treatment plans, and in kidney and urologic conditions the consequences of missed medications, inconsistent device use, or failure to follow dietary and behavioral guidance can be severe. The FOA is built around the idea that adherence is not a minor quality-of-life issue but a major driver of morbidity and mortality, especially when treatment regimens are complex, long-term, and feel inflexible to young people trying to manage school, social life, and a growing push toward independence.
A central motivation of the announcement is that adolescence is a uniquely high-risk period for nonadherence. Developmentally, teens are balancing autonomy, identity formation, shifting family roles, and changing executive function skills, all while responsibilities for medical self-management often increase. For adolescents with chronic kidney disease or urologic disorders, adherence demands can include multiple daily medications, dietary restrictions, fluid management, catheterization or other device-related care, clinic attendance, and behavior changes that are hard to maintain consistently. The FOA emphasizes that while adherence has been studied more extensively in pediatric HIV, there are comparatively few rigorous pediatric adherence studies in other chronic illnesses, leaving real gaps in evidence about what drives nonadherence and what interventions actually work for kidney and urologic populations.
The purpose of the FOA is to support research that improves adherence in adolescents with chronic kidney or urologic diseases. It invites applications from both new and established investigators and points to three broad, connected research needs: first, better understanding of the factors that influence adherence in this group (which can include patient-level, family-level, health system, and social or environmental drivers); second, development and validation of appropriate adherence measures (because adherence is often hard to measure accurately, and different regimens require different measurement approaches); and third, testing innovative strategies designed to enhance adherence in this vulnerable population. In practical terms, this encourages projects that move beyond simply documenting that nonadherence exists and instead build toward measurable, testable solutions, including interventions that can be evaluated for effectiveness.
In terms of award structure, this is an R01 mechanism, meaning it supports substantial, hypothesis-driven research projects. The announcement anticipated about three awards, with an estimated total funding amount of approximately $1,330,000. The award ceiling listed is $450,000. There is no cost-sharing or matching requirement, which lowers barriers for applicants that might otherwise struggle to provide institutional matching funds.
Eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants span public and private institutions of higher education, nonprofits (both 501(c)(3) and non-501(c)(3)), small businesses and other for-profit organizations (other than small businesses are explicitly listed as eligible), independent school districts, and multiple levels of government (state, county, city/township, special district). The FOA also specifies additional eligible entities such as historically underrepresented and mission-focused institutions and organizations, including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, AANAPISIs, federally recognized tribal governments and other tribal organizations, faith-based or community-based organizations, U.S. territories or possessions, regional organizations, federal agencies, and foreign organizations (non-U.S. entities). This wide eligibility reflects the reality that adherence research and intervention testing can be conducted in many settings, including academic medical centers, community-based clinics, school-linked health programs, and multi-site collaborations.
Key dates show that the opportunity was posted and created on June 5, 2015, with an original and current closing date of November 2, 2015, and an archive date of December 3, 2015. While that indicates the specific FOA is no longer active, the content still provides a clear snapshot of NIH priorities at the time: improving real-world health outcomes for adolescents with kidney or urologic disease by funding research that clarifies why adherence breaks down, how to measure it properly, and how to design interventions that fit adolescent development and daily life rather than expecting adolescents to fit rigid care plans without support.
The sponsoring agency is NIH, and the associated CFDA number listed is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), aligning the program with the NIH institute portfolio that covers kidney-related research. For full details, the FOA provided an official link through the NIH Grants Guide (http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-15-017.html). For technical access issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, which is intended for problems accessing or linking to the announcement rather than scientific program questions.
Frequently Asked Questions (FAQs)
What is the title and funding opportunity number for this grant?
The funding opportunity is titled "Adherence Studies in Adolescents with Chronic Kidney or Urologic Diseases (R01)". The Funding Opportunity Number (FOA) is RFA-DK-15-017.
Which agency is sponsoring this funding opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
What is the main purpose of this FOA?
The FOA supports research aimed at improving adherence among adolescents with chronic kidney disease or urologic disorders. The focus is on understanding why adherence breaks down, improving how adherence is measured, and testing strategies that can increase adherence in real life.
Why does the FOA focus specifically on adolescents?
The FOA treats adolescence as a uniquely high-risk period for nonadherence due to developmental and life-context factors like increasing independence, changing family roles, executive function development, and competing school and social demands, all while medical self-management responsibilities often increase.
What kinds of adherence demands are discussed for kidney or urologic conditions?
The FOA highlights that adherence may involve complex, ongoing tasks such as multiple daily medications, dietary restrictions, fluid management, catheterization or other device-related care, clinic attendance, and behavior changes that can be difficult to sustain consistently.
What problem is this FOA trying to address in pediatric care?
The FOA is built around the idea that nonadherence is not just a quality-of-life issue; it is a major driver of morbidity and mortality, especially when treatment regimens are complex and long-term and feel inflexible to adolescents.
What research gaps does the FOA point to?
The FOA notes that while adherence research has been studied more extensively in pediatric HIV, there are comparatively few rigorous pediatric adherence studies in other chronic illnesses, including kidney and urologic diseases. This creates gaps in evidence about the causes of nonadherence and which interventions truly work in these populations.
What types of research does the FOA encourage?
The FOA describes three connected research needs:
- Understanding factors that influence adherence (patient, family, health system, and social/environmental drivers)
- Developing and validating appropriate adherence measures (since adherence is difficult to measure and differs by regimen)
- Testing innovative strategies designed to enhance adherence in adolescents with kidney or urologic diseases
Does the FOA prioritize solutions over simply documenting nonadherence?
Yes. The FOA encourages projects that move beyond describing nonadherence and instead build toward measurable, testable solutions, including interventions that can be evaluated for effectiveness.
What funding mechanism is used?
This FOA uses the R01 mechanism, which supports substantial, hypothesis-driven research projects.
How many awards were expected and what was the estimated total funding?
The FOA anticipated about three awards, with an estimated total funding amount of approximately $1,330,000.
What is the award ceiling listed in the FOA?
The award ceiling listed is $450,000.
Is cost-sharing or matching required?
No. The FOA states there is no cost-sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad and includes many domestic and non-domestic organization types, including:
- Public and private institutions of higher education
- Nonprofits (501(c)(3) and non-501(c)(3))
- Small businesses and other for-profit organizations (including those other than small businesses)
- Independent school districts
- State, county, city/township, and special district governments
- Federal agencies
- U.S. territories or possessions and regional organizations
- Foreign organizations (non-U.S. entities)
- Faith-based and community-based organizations
- Tribal governments and other tribal organizations
- HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, AANAPISIs, and other mission-focused/underrepresented institutions
Are foreign (non-U.S.) organizations eligible?
Yes. The FOA explicitly includes foreign organizations (non-U.S. entities) among eligible applicants.
What is the CFDA number associated with this opportunity?
The associated CFDA number listed is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).
What are the key dates for this FOA?
The FOA was posted/created on June 5, 2015. The original and current closing date is November 2, 2015. The archive date is December 3, 2015.
Is this FOA still active?
No. Based on the closing date (November 2, 2015) and the archive date (December 3, 2015), this specific FOA is no longer active.
Where can the official FOA text be found?
The FOA provides an official NIH Grants Guide link: http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-15-017.html
Who should be contacted for technical problems accessing the announcement link?
For technical access issues (problems accessing or linking to the announcement), the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Is the listed contact meant for scientific or programmatic questions?
No. The FOA specifies that the listed contact is intended for technical access issues related to accessing or linking to the announcement, not for scientific program questions.
What overall priority does this FOA reflect?
It reflects an NIH priority to improve real-world outcomes for adolescents with kidney or urologic disease by funding research that clarifies why adherence fails, establishes how to measure adherence properly, and designs interventions aligned with adolescent development and daily life.
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