Opportunity Information: Apply for PA 15 034
Apply for PA 15 034
- The National Institutes of Health in the education environment food and nutrition health income security and social services sector is offering a public funding opportunity titled "Administrative Supplements for Research on Sex/Gender Differences (Admin Supp)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.233 National Center on Sleep Disorders Research 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.307 Minority Health and Health Disparities Research 93.313 NIH Office of Research on Womens Health 93.351 Research Infrastructure Programs 93.361 Nursing Research 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research 93.879 Medical Library Assistance 93.989 International Research and Research Training.
- This funding opportunity was created on Nov 14, 2014 and posted on Nov 14, 2014.
- Applicants must submit their applications by Jan 12, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $7,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $100,000.00 in funding.
- The number of recipients for this funding is limited to 70 candidate(s).
- Eligible applicants include: For profit organizations other than small businesses Native American tribal governments (Federally recognized) Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education County governments Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities City or township governments State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession This announcement is for supplements to existing projects. To be eligible, the parent award must be active and the research proposed in the supplement must be accomplished within the competitive segment. The proposed supplement must be to provide for an increase in costs due to unforeseen circumstances. All additional costs must be within the scope of the peer reviewed and approved project. IMPORTANT The research proposed by the NIH grantee in the supplement application must be within the original scope of the NIH supported grant project. Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
Administrative Supplements for Research on Sex/Gender Differences (PA 15-034) is a National Institutes of Health (NIH) funding opportunity administered through the Office of Research on Womens Health (ORWH). It offers administrative supplement grants to add targeted, within-scope work to already funded NIH projects, specifically to strengthen or expand research that examines how sex and/or gender influences health and disease. The core idea is to help active NIH-funded projects incorporate or deepen analyses of sex/gender differences (or similarities) and sex- and gender-related factors across the full research spectrum, including basic science, preclinical studies, clinical research, and behavioral investigations.
The scientific emphasis is on work that clarifies the role of biological sex and gender-relevant factors in human health and illness. ORWH highlights particular interest in studies that look at the significance of biological sex at the cellular level; comparative studies using male and female tissues; comparisons across organ systems and physiological systems; and sex-based contrasts in pathophysiology, biomarkers, gene expression, and clinical presentation. The opportunity also supports research that improves understanding of whether prevention strategies or treatments work differently in males and females, or how sex/gender may shape disease risk, progression, and response to interventions.
A key requirement is alignment with the NIH Strategic Plan for Womens Health Research. Proposed supplement activities must address at least one objective under Goals 1 through 3 of that strategic plan, which generally focus on advancing rigorous research on sex and gender influences, improving the evidence base across conditions and life stages, and strengthening the integration of sex as a biological variable and gender-related considerations in health research. In practice, applicants need to clearly connect their proposed supplement aims to at least one relevant objective in those goals.
This is not a standalone grant mechanism. It is strictly for administrative supplements to existing NIH awards, meaning the parent grant must already be active. The supplement work must be feasible within the remaining competitive segment of the parent award, and the request must stay within the original scientific scope of what was peer reviewed and approved for the parent project. The announcement also notes that supplements are intended to cover increases in costs due to unforeseen circumstances, and any additional costs must be justified as part of completing the approved project as supplemented.
From a funding and logistics standpoint, the announcement projected about 70 awards with an estimated total funding level of about $7,000,000. The maximum (award ceiling) per supplement was listed as $100,000, and there was no cost sharing or matching requirement. The opportunity was posted November 14, 2014, with an application closing date of January 12, 2015, and it was archived February 12, 2015.
Eligibility is broad for U.S.-based organizations, spanning public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses), state and local governments, tribal governments and tribal organizations, public housing authorities, independent school districts, and a range of mission-serving institutions such as HBCUs, Hispanic-serving institutions, AANAPISIs, TCCUs, and Alaska Native and Native Hawaiian-serving institutions. Foreign (non-U.S.) institutions are not eligible to apply directly, but foreign components are allowed under NIH policy, and non-U.S. components of U.S. organizations may be eligible.
The scope of participating NIH programs is reflected in the wide set of CFDA numbers tied to the announcement, covering many biomedical and behavioral research areas such as cancer, cardiovascular disease, mental health, substance use, aging, child health, diabetes and kidney disease, infectious disease, neuroscience, minority health and health disparities, nursing research, and more. Overall, the supplement is designed to quickly and efficiently enhance ongoing NIH-funded research by ensuring sex and gender considerations are meaningfully integrated into study design, analysis, and interpretation where relevant, ultimately improving the rigor and real-world applicability of health findings for everyone.
Frequently Asked Questions (FAQs)
What is the Administrative Supplements for Research on Sex/Gender Differences (PA 15-034)?
PA 15-034 is a National Institutes of Health (NIH) funding opportunity administered through the Office of Research on Womens Health (ORWH). It provides administrative supplement grants to add targeted, within-scope work to already funded NIH projects to strengthen or expand research examining how sex and/or gender influences health and disease.
Is this a standalone grant, or does it require an existing NIH award?
This is not a standalone grant. It is strictly an administrative supplement to an existing NIH award. The parent grant must already be active.
What is the main purpose of this supplement program?
The purpose is to help active NIH-funded projects incorporate or deepen analyses of sex/gender differences (or similarities) and sex- and gender-related factors across the research spectrum, including basic science, preclinical studies, clinical research, and behavioral investigations.
What kinds of research activities does the supplement aim to support?
The supplement supports targeted work that clarifies the role of biological sex and gender-relevant factors in human health and illness. This includes efforts to meaningfully integrate sex and gender considerations into study design, analysis, and interpretation where relevant.
What scientific areas or approaches are highlighted as priorities by ORWH?
ORWH highlights particular interest in studies such as:
- Research examining the significance of biological sex at the cellular level
- Comparative studies using male and female tissues
- Comparisons across organ systems and physiological systems
- Sex-based contrasts in pathophysiology, biomarkers, gene expression, and clinical presentation
- Work assessing whether prevention strategies or treatments work differently in males and females
- Research on how sex/gender may shape disease risk, progression, and response to interventions
Which stages or types of research are eligible for supplement activities?
The opportunity is intended to apply across the full research spectrum, including basic science, preclinical studies, clinical research, and behavioral investigations, as long as the proposed supplement work remains within the scope of the active parent NIH award.
Does the supplement focus only on differences between males and females?
The program is designed to support research that examines how sex and/or gender influences health and disease, including sex/gender differences and similarities, as well as sex- and gender-related factors that may affect outcomes.
What does "within-scope" mean for a supplement request under this opportunity?
The supplement work must stay within the original scientific scope that was peer reviewed and approved for the parent project. The activities should be a targeted addition that strengthens or expands sex/gender-related analyses without changing the fundamental purpose of the parent award.
Does the parent award need to be in a specific phase or time period?
Yes. The parent grant must be active, and the proposed supplement activities must be feasible within the remaining competitive segment of the parent award.
How does this opportunity relate to the NIH Strategic Plan for Womens Health Research?
Alignment with the NIH Strategic Plan for Womens Health Research is a key requirement. Proposed supplement activities must address at least one objective under Goals 1 through 3 of the plan, which broadly emphasize rigorous research on sex and gender influences, strengthening the evidence base across conditions and life stages, and integrating sex as a biological variable and gender-related considerations into health research.
How specific does the application need to be about alignment with the Strategic Plan objectives?
Applicants need to clearly connect their proposed supplement aims to at least one relevant objective within Goals 1 through 3 of the NIH Strategic Plan for Womens Health Research.
What funding level was projected for this opportunity?
The announcement projected about 70 awards with an estimated total funding level of about $7,000,000.
What is the maximum amount that can be requested per supplement?
The listed award ceiling per supplement was $100,000.
Is cost sharing or matching required?
No. The opportunity indicated that there was no cost sharing or matching requirement.
What kinds of costs are supplements intended to cover?
The announcement notes that supplements are intended to cover increases in costs due to unforeseen circumstances, and any additional costs must be justified as part of completing the approved project as supplemented.
Who administers this NIH funding opportunity?
This funding opportunity is administered through the NIH Office of Research on Womens Health (ORWH).
Which NIH research areas does this opportunity touch?
The opportunity is associated with a wide set of CFDA numbers spanning many biomedical and behavioral research areas, including (as examples) cancer, cardiovascular disease, mental health, substance use, aging, child health, diabetes and kidney disease, infectious disease, neuroscience, minority health and health disparities, and nursing research.
What types of U.S.-based organizations are eligible to apply?
Eligibility is broad for U.S.-based organizations and includes public and private institutions of higher education; nonprofits (including 501(c)(3) and certain non-501(c)(3) entities); for-profit organizations (including small businesses); state and local governments; tribal governments and tribal organizations; public housing authorities; independent school districts; and a range of mission-serving institutions such as HBCUs, Hispanic-serving institutions, AANAPISIs, TCCUs, and Alaska Native and Native Hawaiian-serving institutions.
Are foreign (non-U.S.) institutions eligible to apply directly?
No. Foreign (non-U.S.) institutions are not eligible to apply directly under this opportunity.
Are foreign components allowed if the applicant is a U.S. organization?
Yes. Foreign components are allowed under NIH policy, and non-U.S. components of U.S. organizations may be eligible.
When was this opportunity posted and when did it close?
The opportunity was posted on November 14, 2014. The application closing date was January 12, 2015.
Is this funding opportunity still open?
No. The announcement was archived on February 12, 2015.
What is the overall goal of adding sex and gender considerations to ongoing NIH-funded studies?
The supplement is designed to quickly and efficiently enhance ongoing NIH-funded research by ensuring sex and gender considerations are meaningfully integrated into study design, analysis, and interpretation where relevant, improving rigor and the real-world applicability of health findings.
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