Opportunity Information: Apply for PA 16 164

  • The HHS-NIH11 in the education, health, income security and social services sector is offering a public funding opportunity titled "Administrative Supplements for Research on Sleep Disturbances and Impact on Chronic Pain (Admin Supp)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213, 93.279, 93.865,.
  • This funding opportunity was created on Apr 04, 2016 and posted on Apr 04, 2016.
  • Applicants must submit their applications by Jun 24, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $100,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:

The NIH funding opportunity PA-16-164, titled "Administrative Supplements for Research on Sleep Disturbances and Impact on Chronic Pain (Admin Supp)," offered a one-time administrative supplement to support add-on work within existing, active clinical research grants. The focus was specifically on improving what is known about the relationship between sleep disturbances and chronic pain, with the expectation that the supplement-funded activities would generate insights, preliminary findings, or methodological advances that could inform future, larger-scale studies directly examining how sleep and chronic pain interact.

This was not a standalone grant mechanism for starting a brand-new project from scratch. Instead, it was designed for investigators who already held eligible NIH-supported clinical research awards from a limited set of NIH Institutes and Centers and within specific activity codes (as referenced in the announcement). The key requirement was that the proposed supplement work had to remain within the originally peer-reviewed and approved scope of the parent award. In practical terms, the supplement could extend or enhance what the parent study was already doing, but it could not change the project into something fundamentally different. Another important constraint was timing: the proposed aims and deliverables needed to be feasible within the remaining budget period of the parent grant, since the supplement work had to be completed before the parent award ended.

The FOA emphasized flexible, pragmatic research additions that take advantage of studies already underway. Examples of allowable activities included adding sleep assessment to an existing clinical study primarily focused on pain, adding pain assessment to an existing clinical study primarily focused on sleep, and expanding or refining the measurement of sleep and/or pain in studies that already include one or both. It also allowed adding additional data collection time points to strengthen longitudinal understanding, such as capturing sleep and pain measures at more frequent intervals or at clinically meaningful follow-up points already aligned with the study schedule. In addition to new data collection, the FOA explicitly allowed secondary data analysis of existing clinical study datasets to examine how sleep disturbance may contribute to chronic pain outcomes, again provided those analyses fit within the parent project scope and could be completed during the remaining funding window.

From a funding and administrative standpoint, the opportunity was offered by HHS/NIH (listed as HHS-NIH11), categorized as a discretionary grant. The maximum supplement amount was listed as an award ceiling of $100,000. The opportunity was posted April 4, 2016, with a closing date of June 24, 2016. The associated CFDA numbers included 93.213, 93.279, and 93.865, reflecting the NIH program areas linked to the parent awards that could potentially qualify.

Eligibility was broad in the sense that many organization types could apply, including state, county, and local governments; public and private institutions of higher education; nonprofit organizations (both with and without 501(c)(3) status); for-profit organizations (other than small businesses) and small businesses; tribal governments and tribal organizations; public housing authorities; and other entities as described in the NIH eligibility text. That said, because this was an administrative supplement, practical eligibility depended heavily on whether the applicant already held an eligible NIH clinical research award from the participating Institutes and Centers and in the permitted activity codes.

Overall, the intent of PA-16-164 was to quickly and efficiently leverage ongoing clinical research to deepen understanding of sleep-pain connections. By funding targeted additions such as extra measures, added time points, or focused analyses, NIH aimed to accelerate the development of methods and early evidence needed to justify and design future, more definitive studies on the bidirectional links between sleep disturbance and chronic pain.

FAQs: NIH PA-16-164 - Administrative Supplements for Research on Sleep Disturbances and Impact on Chronic Pain (Admin Supp)

What is PA-16-164?

PA-16-164 is an NIH funding opportunity titled "Administrative Supplements for Research on Sleep Disturbances and Impact on Chronic Pain (Admin Supp)." It offered a one-time administrative supplement to add targeted sleep and/or pain-related research activities onto an existing, active NIH-supported clinical research grant.

Is this a standalone grant for a brand-new research project?

No. This was not a mechanism for starting a new project from scratch. The supplement was intended only for add-on work that fits within the scope of an existing, active parent clinical research award.

What was the main goal of the supplement?

The goal was to improve understanding of the relationship between sleep disturbances and chronic pain by leveraging studies already underway. NIH expected supplement-supported activities to produce insights, preliminary findings, or methodological advances that could inform future, larger-scale studies focused on sleep-pain interactions.

Who could practically apply for PA-16-164?

In practice, applicants needed to already hold an eligible NIH-supported clinical research award from participating NIH Institutes and Centers and within the activity codes permitted by the announcement. Because it is an administrative supplement, the key practical eligibility requirement is having an appropriate active parent award.

What types of organizations were eligible to apply?

The eligible organization types listed included state, county, and local governments; public and private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status); for-profit organizations (other than small businesses) and small businesses; tribal governments and tribal organizations; public housing authorities; and other entities as described in NIH eligibility text.

What is an "administrative supplement" in this context?

In this context, an administrative supplement is additional funding to support extra, targeted work added onto an existing funded project. The added work must stay within the originally peer-reviewed and approved scope of the parent award and be doable within the remaining budget period.

What does "within the scope of the parent award" mean?

It means the supplement activities can extend or enhance what the funded parent study is already doing, but they cannot change the project into something fundamentally different from what was originally reviewed and approved. The supplement must remain consistent with the parent grant's overall aims and purpose.

How did timing affect what could be proposed?

The supplement work had to be completed before the parent award ended. Proposed aims and deliverables needed to be feasible within the remaining budget period of the active parent grant.

What kinds of research activities were allowed under this supplement?

The FOA emphasized flexible, pragmatic additions that take advantage of studies already underway. Examples included adding sleep assessment to an ongoing pain-focused clinical study, adding pain assessment to a sleep-focused clinical study, or expanding/refining sleep and/or pain measurement in studies that already include one or both.

Could applicants add additional data collection time points?

Yes. The FOA allowed adding additional data collection time points to strengthen longitudinal understanding, such as measuring sleep and pain more frequently or at clinically meaningful follow-up points aligned with the existing study schedule.

Was secondary analysis of existing clinical datasets allowed?

Yes. The FOA explicitly allowed secondary data analysis of existing clinical study datasets to examine how sleep disturbance may contribute to chronic pain outcomes, as long as the work fit within the parent project scope and could be completed within the remaining funding window.

Could the supplement be used to add sleep measures to a pain study (or vice versa)?

Yes. One of the core examples of allowable work was adding sleep assessment to an existing clinical study primarily focused on pain, or adding pain assessment to an existing clinical study primarily focused on sleep.

What was the maximum funding amount for the supplement?

The award ceiling listed for the administrative supplement was $100,000.

Which agency offered this funding opportunity?

The opportunity was offered by HHS/NIH (listed as HHS-NIH11) and categorized as a discretionary grant.

When was PA-16-164 posted and when did it close?

The opportunity was posted on April 4, 2016, and it closed on June 24, 2016.

What were the CFDA numbers associated with this opportunity?

The associated CFDA numbers included 93.213, 93.279, and 93.865, reflecting NIH program areas linked to the parent awards that could potentially qualify.

Did the FOA require that supplement outcomes support future research?

Yes. The FOA emphasized generating early evidence, insights, or methodological advances that could justify and help design future, more definitive studies on the bidirectional links between sleep disturbance and chronic pain.

Could a supplement proposal fundamentally redirect the parent study to focus primarily on sleep and pain?

No. The supplement could enhance the parent project but could not turn it into a fundamentally different project. Any added aims needed to remain consistent with the parent award's originally approved scope.

What is meant by "one-time" administrative supplement?

It indicates the FOA offered a single, non-recurring opportunity for additional funding to support the specified add-on work during the active parent award period, rather than ongoing or renewable standalone funding.

What was the overarching research theme NIH wanted to accelerate?

NIH aimed to accelerate understanding of how sleep disturbances and chronic pain interact, using efficient add-on studies and analyses that build on existing clinical research infrastructure and data.

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