Opportunity Information: Apply for RFA DA 15 016
Apply for RFA DA 15 016
- The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Adolescent Brain Cognitive Development (ABCD) Study Data Analysis and Informatics Center (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.307 Minority Health and Health Disparities Research 93.399 Cancer Control 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Feb 4, 2015 and posted on Feb 4, 2015.
- Applicants must submit their applications by Apr 14, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $3,000,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Private institutions of higher education County governments Independent school districts For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The Adolescent Brain Cognitive Development (ABCD) Study Data Analysis and Informatics Center (U24) opportunity (RFA-DA-15-016) is a National Institutes of Health (NIH) cooperative agreement designed to support the data backbone of a large, national research effort focused on adolescent development and substance use. It is part of the Collaborative Research on Addiction at the NIH (CRAN), led by the National Institute on Drug Abuse (NIDA) with substantial involvement from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Cancer Institute (NCI), and additional NIH partners including NICHD, NIMH, NIMHD, and OBSSR. The broader ABCD Study Consortium is built to follow a large cohort of children starting in early adolescence (about ages 9 to 10) and track them longitudinally through the years when the risk for initiating substance use and developing substance use disorders increases. The central scientific goal is to prospectively examine how substance use relates to neurodevelopmental, cognitive, and behavioral trajectories over time.
This specific FOA funds one award for a single, centralized Data Analysis and Informatics Center, which is one of three tightly integrated consortium components. The other two components are a network of Research Project Sites (solicited under the companion FOA RFA-DA-15-015) and a single overall Coordinating Center (solicited under RFA-DA-15-014). Together, these parts form an interdependent system: research sites collect data, the coordinating center manages overall operations and harmonization, and the data analysis and informatics center provides the infrastructure and expertise to manage, curate, analyze, and disseminate the study data in a way that supports the consortium and maximizes scientific value.
Because this is a cooperative agreement (U24), it is not a hands-off grant where the awardee works independently. Instead, NIH scientific staff are expected to be actively involved with the funded team to help guide, coordinate, and participate in major project activities. Applications could be submitted as linked packages alongside applications for the other consortium components, but the FOA also allowed unlinked applications; if selected, they would be linked after peer review to assemble the final consortium.
From an administrative standpoint, this was a discretionary funding opportunity with an expected single award and an estimated total funding amount of about $3,000,000. It did not require cost sharing or matching. The opportunity was posted on February 4, 2015, with an application closing date of April 14, 2015, and it was later archived on May 15, 2015. The program aligns with multiple CFDA areas reflecting the multi-institute nature of the effort, including drug abuse and addiction research, alcohol research, mental health research, minority health and health disparities research, cancer control, and child health and development research.
Eligibility was broad across U.S.-based organizations and governmental entities, reflecting the technical and operational demands of running a national-scale data and informatics hub. Eligible applicants included public and private institutions of higher education, nonprofit organizations with or without 501(c)(3) status, for-profit organizations (other than small businesses), small businesses, independent school districts, and multiple levels of government (state, county, city or township), as well as special district governments and public housing/Indian housing authorities. The FOA also explicitly included various mission-driven and capacity-building institution types such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, AANAPISIs, Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, and eligible federal agencies. Foreign institutions were not eligible, and non-U.S. components of U.S. organizations were not allowed; foreign components as defined by NIH policy were not permitted.
In practical terms, an applicant to this FOA was being asked to serve as the consortiums central engine for data handling and analytic support, operating in close partnership with NIH and with the other ABCD components. The intent was to ensure that the enormous volume and complexity of longitudinal, multisite adolescent neurodevelopment and behavioral data could be reliably managed, harmonized, and made usable for high-quality, reproducible science across the life of the study.
Frequently Asked Questions (FAQs)
What is the ABCD Study Data Analysis and Informatics Center (U24) opportunity?
This opportunity (RFA-DA-15-016) is a National Institutes of Health (NIH) cooperative agreement (U24) to support a single, centralized Data Analysis and Informatics Center for the Adolescent Brain Cognitive Development (ABCD) Study. The Center is intended to serve as the consortium's core hub for managing, curating, analyzing, and disseminating ABCD study data.
What is the ABCD Study trying to accomplish overall?
The ABCD Study Consortium is designed to follow a large cohort of children beginning in early adolescence (about ages 9 to 10) and track them longitudinally through the period when risk for initiating substance use and developing substance use disorders increases. The central scientific goal is to prospectively examine how substance use relates to neurodevelopmental, cognitive, and behavioral trajectories over time.
Which NIH initiatives and institutes are involved?
This effort is part of the Collaborative Research on Addiction at the NIH (CRAN). It is led by the National Institute on Drug Abuse (NIDA), with substantial involvement from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Cancer Institute (NCI). Additional NIH partners named include NICHD, NIMH, NIMHD, and OBSSR.
How many awards were expected under this FOA?
The FOA funded one award for a single, centralized Data Analysis and Informatics Center.
How does this Center fit into the larger ABCD Study Consortium structure?
The Data Analysis and Informatics Center is one of three tightly integrated consortium components. The other two are: (1) a network of Research Project Sites (solicited under the companion FOA RFA-DA-15-015) and (2) a single overall Coordinating Center (solicited under RFA-DA-15-014). The components are designed to operate as an interdependent system where research sites collect data, the coordinating center manages overall operations and harmonization, and the data analysis/informatics center provides data infrastructure and analytic support.
What would the funded Data Analysis and Informatics Center be expected to do?
Based on the description provided, the funded Center would be expected to provide the data backbone for the consortium by managing, curating, analyzing, and disseminating ABCD study data. The intent is to ensure that a very large, complex, longitudinal, multisite dataset can be reliably handled, harmonized, and made usable for high-quality, reproducible science throughout the life of the study.
What does it mean that this is a cooperative agreement (U24)?
A U24 cooperative agreement is not a hands-off grant. NIH scientific staff are expected to be actively involved with the funded team to help guide, coordinate, and participate in major project activities.
Can this application be submitted on its own, or does it have to be linked with the other ABCD component applications?
The FOA allowed applications to be submitted as linked packages alongside applications for the other consortium components, but it also allowed unlinked applications. If selected, unlinked applications would be linked after peer review to assemble the final consortium.
What was the expected funding amount for this opportunity?
The estimated total funding amount was about $3,000,000.
Was cost sharing or matching required?
No. The opportunity did not require cost sharing or matching.
What were the key dates for this FOA?
The opportunity was posted on February 4, 2015. The application closing date was April 14, 2015. It was later archived on May 15, 2015.
Is this funding opportunity still active?
No. The FOA was archived on May 15, 2015.
What types of organizations were eligible to apply?
Eligibility was broad across U.S.-based organizations and governmental entities. Eligible applicants included public and private institutions of higher education, nonprofit organizations with or without 501(c)(3) status, for-profit organizations (other than small businesses), small businesses, independent school districts, and multiple levels of government (state, county, city or township), as well as special district governments and public housing/Indian housing authorities.
Were any specific institution types explicitly included?
Yes. The FOA explicitly included a range of mission-driven and capacity-building institution types, including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, AANAPISIs, Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, and eligible federal agencies.
Are foreign organizations eligible to apply?
No. Foreign institutions were not eligible.
Can a U.S. organization include a non-U.S. component or foreign component?
No. Non-U.S. components of U.S. organizations were not allowed, and foreign components (as defined by NIH policy) were not permitted.
What was the administrative type of this opportunity?
It was described as a discretionary funding opportunity with an expected single award.
What research and program areas does this opportunity align with (CFDA areas)?
The program aligns with multiple CFDA areas reflecting the multi-institute nature of the effort, including drug abuse and addiction research, alcohol research, mental health research, minority health and health disparities research, cancer control, and child health and development research.
Why does the ABCD Study need a dedicated Data Analysis and Informatics Center?
The intent described is to ensure that the enormous volume and complexity of longitudinal, multisite adolescent neurodevelopment and behavioral data can be reliably managed, harmonized, and made usable for high-quality, reproducible science across the life of the study.
Who leads the broader effort?
The effort is led by NIDA as part of CRAN, with substantial involvement from NIAAA and NCI and additional NIH partners including NICHD, NIMH, NIMHD, and OBSSR.
What is the relationship between the research sites, coordinating center, and the data analysis/informatics center?
The description outlines a division of roles: research sites collect data, the coordinating center manages overall operations and harmonization, and the data analysis and informatics center provides the infrastructure and expertise to manage, curate, analyze, and disseminate the study data to support the consortium and maximize scientific value.
What is the main subject focus of the ABCD Study described here?
The focus is adolescent development and substance use, with a scientific emphasis on how substance use relates to neurodevelopmental, cognitive, and behavioral trajectories over time in a prospectively followed cohort starting around ages 9 to 10.
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