Opportunity Information: Apply for PA 12 189
Apply for PA 12 189
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Advanced Tools and Technologies for Cerebrospinal Fluid Shunts SBIR (R43/R44)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on May 31, 2012 and posted on May 31, 2012.
- Applicants must submit their applications by May 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Opportunity Summary:
The Advanced Tools and Technologies for Cerebrospinal Fluid Shunts SBIR (R43/R44) opportunity (Funding Opportunity Number PA 12-189) was a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) grant program focused on improving care for people with hydrocephalus by supporting the design and development of better cerebrospinal fluid (CSF) shunt tools and technologies. The central purpose of the announcement was to encourage small business concerns to create innovations that could meaningfully improve the clinical performance, safety, reliability, and overall treatment outcomes associated with CSF shunting, which remains a common and often complication-prone therapy for hydrocephalus.
This was a discretionary grant opportunity under the federal activity category of Health, Income Security, and Social Services, and it used the SBIR R43/R44 mechanisms. In practical terms, that means it was structured for small businesses developing early-stage and next-stage R&D: Phase I (R43) generally supports feasibility and proof-of-concept work, while Phase II (R44) supports more advanced development and validation aimed at moving a technology closer to clinical use and commercialization. The announcement specifically targeted projects that would produce advanced tools and technologies for CSF shunts, reflecting NIH interest in fostering new engineering approaches, smarter devices, improved components, monitoring capabilities, and other enabling technologies that could reduce failure rates and improve patient management.
Eligibility was limited to small businesses, consistent with SBIR rules, and there was no cost sharing or matching requirement, which is typical for SBIR awards and lowers the barrier for early technology development. The administering agency was NIH, with the opportunity associated with CFDA numbers 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders) and 93.865 (Child Health and Human Development Extramural Research), signaling relevance to both neurological disorders broadly and pediatric or developmental aspects of hydrocephalus care.
From an administrative timeline standpoint, the FOA was posted and created on May 31, 2012, and it originally closed on May 7, 2015, with the same date listed as the current closing date at the time; it was archived on June 7, 2015. Applicants looking for the complete archived announcement were directed to the NIH grants page at http://grants.nih.gov/grants/guide/pa-files/PA-12-189.html. For access or technical issues with the online announcement, the listed point of contact was the NIH Office of Extramural Research (OER) Webmaster (FBOWebmaster@OD.NIH.GOV), including support for both accessing the full FOA text and resolving linking problems.
Overall, this program can be understood as NIH using the SBIR pipeline to help small companies translate practical innovations in shunt technology into real-world clinical improvements for hydrocephalus patients, with an emphasis on developing next-generation tools that could address persistent shortcomings in existing CSF shunt systems.
Frequently Asked Questions (FAQs)
What is the “Advanced Tools and Technologies for Cerebrospinal Fluid Shunts SBIR (R43/R44)†opportunity?
It was a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) grant opportunity focused on improving care for people with hydrocephalus by supporting the design and development of better cerebrospinal fluid (CSF) shunt tools and technologies.
What is the Funding Opportunity Number (FON) for this program?
The Funding Opportunity Number was PA 12-189.
What problem area or clinical need was this program designed to address?
The program targeted hydrocephalus treatment, specifically CSF shunting, which is a common therapy that can be complication-prone. The intent was to spur innovations that improve clinical performance, safety, reliability, and overall treatment outcomes associated with CSF shunts.
What types of projects was NIH looking to support under this announcement?
The announcement encouraged small businesses to create advanced tools and technologies for CSF shunts, including innovations such as new engineering approaches, smarter devices, improved components, monitoring capabilities, and other enabling technologies intended to reduce shunt failure rates and improve patient management.
Which grant mechanisms were used for this opportunity?
This opportunity used SBIR mechanisms R43 and R44.
How do Phase I (R43) and Phase II (R44) differ under this SBIR opportunity?
Phase I (R43) generally supported feasibility and proof-of-concept work. Phase II (R44) generally supported more advanced development and validation intended to move a technology closer to clinical use and commercialization.
Who was eligible to apply?
Eligibility was limited to small businesses, consistent with SBIR rules.
Was cost sharing or a matching requirement required?
No. The opportunity stated there was no cost sharing or matching requirement, which is typical for SBIR awards.
Which federal agency administered the program?
The administering agency was the National Institutes of Health (NIH).
What was the federal activity category for this grant opportunity?
This was a discretionary grant opportunity under the federal activity category of Health, Income Security, and Social Services.
Which CFDA numbers were associated with this opportunity?
The opportunity was associated with CFDA 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders) and CFDA 93.865 (Child Health and Human Development Extramural Research).
What do the listed CFDA numbers suggest about the program’s focus?
They signal relevance to neurological disorders broadly (neurosciences and neurological disorders) and also to child health and human development, reflecting the clinical relevance of hydrocephalus care across populations including pediatric and developmental contexts.
When was the FOA posted and created?
The FOA was posted and created on May 31, 2012.
When did the opportunity close?
It originally closed on May 7, 2015, and that same date was listed as the current closing date at the time.
Is the opportunity still open?
No. The announcement was archived on June 7, 2015.
Where can someone find the complete archived announcement?
The archived announcement was available on the NIH grants page at: http://grants.nih.gov/grants/guide/pa-files/PA-12-189.html
Who should be contacted for access or technical issues with the online announcement?
The listed point of contact for access or technical issues was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, including support for accessing the full FOA text and resolving linking problems.
In plain terms, what was NIH trying to accomplish with this SBIR program?
NIH used the SBIR pipeline to help small companies translate practical innovations in shunt technology into real-world clinical improvements for hydrocephalus patients, with an emphasis on next-generation tools that could address persistent shortcomings in existing CSF shunt systems.
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Previous opportunity: FY2012 GDA APS Addendum USAID/Indonesia No. 497 1
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 12 189) also looked into and applied for these:
| Funding Opportunity |
|---|
| Advanced Tools and Technologies for Cerebrospinal Fluid Shunts STTR (R41/R42) Apply for PA 12 190 Funding Number: PA 12 190 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Global Network for Womens and Childrens Health Research (U10) Apply for RFA HD 13 006 Funding Number: RFA HD 13 006 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Data Coordinating Center for the NICHD Cooperative Multicenter Maternal Fetal Medicine Units Research Network (U10) Apply for RFA HD 13 013 Funding Number: RFA HD 13 013 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Data Coordinating Center for the NICHD Cooperative Multicenter Neonatal Research Network (U10) Apply for RFA HD 13 014 Funding Number: RFA HD 13 014 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| NICHD Research Short Courses (R25) Apply for PA 12 207 Funding Number: PA 12 207 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $125,000 |
| Juvenile Protective Factors and Their Effects on Aging (R01) Apply for PAR 12 218 Funding Number: PAR 12 218 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Reproductive Scientist Development Program (RSDP) K12 Apply for RFA HD 13 015 Funding Number: RFA HD 13 015 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Genetic and Genomic Analysis of Xenopus (R21) Apply for PAR 12 249 Funding Number: PAR 12 249 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $200,000 |
| Genetic and Genomic Analysis of Xenopus (R01) Apply for PAR 12 250 Funding Number: PAR 12 250 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Development of Mathematical Cognition and Reasoning and the Prevention of Math Learning Disabilities (R21) Apply for PA 12 246 Funding Number: PA 12 246 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $200,000 |
| Development of Mathematical Cognition and Reasoning and the Prevention of Math Learning Disabilities (R03) Apply for PA 12 247 Funding Number: PA 12 247 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $50,000 |
| Development of Mathematical Cognition and Reasoning and the Prevention of Math Learning Disabilities (R01) Apply for PA 12 248 Funding Number: PA 12 248 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Paul D. Wellstone Muscular Dystrophy Cooperative Research Centers (U54) Apply for RFA AR 13 012 Funding Number: RFA AR 13 012 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Cooperative Multicenter Reproductive Medicine Network (U10) Apply for RFA HD 13 016 Funding Number: RFA HD 13 016 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $200,000 |
| Global Partnerships for Social Science AIDS Research (R24) Apply for RFA HD 13 012 Funding Number: RFA HD 13 012 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
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| Genomic Sequencing and Newborn Screening Disorders (U19) Apply for RFA HD 13 010 Funding Number: RFA HD 13 010 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $1,250,000 |
| Human Heredity and Health in Africa (H3Africa) Collaborative Centers (U54) Apply for RFA RM 12 006 Funding Number: RFA RM 12 006 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Prevention of HIV Transmission/Acquisition through a better understanding of Reproductive Health (R01) Apply for RFA HD 13 008 Funding Number: RFA HD 13 008 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Prevention of HIV Transmission/Acquisition through a better understanding of Reproductive Health (R03) Apply for RFA HD 13 009 Funding Number: RFA HD 13 009 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $50,000 |
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