Opportunity Information: Apply for PA 12 190
Apply for PA 12 190
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Advanced Tools and Technologies for Cerebrospinal Fluid Shunts STTR (R41/R42)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on May 31, 2012 and posted on May 31, 2012.
- Applicants must submit their applications by May 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Opportunity Summary:
The Advanced Tools and Technologies for Cerebrospinal Fluid Shunts STTR (R41/R42) funding opportunity (PA-12-190) is a National Institutes of Health (NIH) discretionary grant program aimed at supporting small business-led research and development projects that improve cerebrospinal fluid (CSF) shunt technology for the treatment of hydrocephalus. The core purpose of the announcement is to encourage the design and development of more advanced tools and technologies related to CSF shunts, with the stated goal of improving clinical care and outcomes for patients who rely on shunting to manage abnormal CSF accumulation.
This opportunity is offered under the Small Business Technology Transfer (STTR) mechanism, which is specifically structured to promote collaboration between a U.S. small business concern (SBC) and a nonprofit research institution. The R41/R42 activity codes indicate a two-phase development path: Phase I (R41) typically supports early-stage feasibility and proof-of-concept work, while Phase II (R42) supports more substantial development, refinement, and validation activities. In practical terms, applicants are expected to propose a project that begins with a clear technical concept and credible feasibility plan, and that can mature into a more complete prototype or technology platform that is realistically positioned for later-stage testing, regulatory planning, and eventual clinical use.
Eligible applicants are limited to small businesses, consistent with the STTR program rules. The announcement is categorized as a grant (FundingInstrumentType: Grant) and falls under the broad activity area of Health, Income Security, and Social Services. It is associated with CFDA numbers 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders) and 93.865 (Child Health and Human Development Extramural Research), reflecting the neurological and pediatric relevance of hydrocephalus and shunt-dependent care. There is no cost sharing or matching requirement, meaning applicants are not required by the announcement to provide matching funds as a condition of eligibility.
From an administrative perspective, the FOA was posted on May 31, 2012, and the original and final closing date listed is May 7, 2015, with an archive date of June 7, 2015. That timeline indicates the program window during which NIH accepted applications under this specific announcement. While the content describes the program’s intent and scope, anyone looking for the full set of application instructions, review criteria, budgeting guidelines, and STTR partnership requirements would need to consult the archived NIH funding announcement page listed in the additional information link.
For access or technical issues related to the online announcement, the point of contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, including support for difficulties accessing the full announcement or problems linking to the funding notice.
Frequently Asked Questions (FAQs)
What is the "Advanced Tools and Technologies for Cerebrospinal Fluid Shunts STTR (R41/R42)" funding opportunity?
This is an NIH discretionary grant funding opportunity (PA-12-190) designed to support small business-led research and development projects focused on improving cerebrospinal fluid (CSF) shunt technology used to treat hydrocephalus.
What is the main goal of this grant program?
The stated goal is to encourage the design and development of more advanced tools and technologies related to CSF shunts, with the intent of improving clinical care and outcomes for patients who depend on shunting to manage abnormal CSF accumulation.
Which agency runs this opportunity?
The opportunity is offered through the National Institutes of Health (NIH).
What type of funding instrument is this?
The announcement is categorized as a grant (FundingInstrumentType: Grant).
What mechanism is used for this program (STTR), and what does it imply?
This opportunity uses the Small Business Technology Transfer (STTR) mechanism, which is specifically structured to promote collaboration between a U.S. small business concern (SBC) and a nonprofit research institution.
Who is eligible to apply?
Eligible applicants are limited to small businesses, consistent with STTR program rules. Projects are expected to involve collaboration with a nonprofit research institution as part of the STTR structure.
What do the activity codes R41 and R42 mean?
R41 and R42 indicate a two-phase development path under STTR. Phase I (R41) typically supports early-stage feasibility and proof-of-concept work. Phase II (R42) typically supports more substantial development, refinement, and validation activities.
What kinds of projects are expected to be proposed under Phase I (R41)?
Applicants are expected to begin with a clear technical concept and a credible feasibility plan, aligning Phase I (R41) with feasibility and proof-of-concept activities.
What kinds of projects are expected to be proposed under Phase II (R42)?
Phase II (R42) is described as supporting more substantial development, refinement, and validation activities, helping a project mature toward a more complete prototype or technology platform.
Is the program focused specifically on hydrocephalus and CSF shunting?
Yes. The opportunity targets tools and technologies related to CSF shunts for the treatment of hydrocephalus, specifically aiming to improve outcomes for shunt-dependent patients managing abnormal CSF accumulation.
What broader topic area does this opportunity fall under?
The announcement falls under the broad activity area of Health, Income Security, and Social Services.
What CFDA numbers are associated with this funding opportunity?
The opportunity is associated with CFDA 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders) and CFDA 93.865 (Child Health and Human Development Extramural Research).
Does this funding opportunity require cost sharing or matching funds?
No. There is no cost sharing or matching requirement stated, meaning applicants are not required by the announcement to provide matching funds as a condition of eligibility.
When was this FOA posted?
The FOA was posted on May 31, 2012.
What was the closing date for applications under this specific announcement?
The original and final closing date listed for this announcement was May 7, 2015.
Is this funding opportunity still open?
No. Based on the provided dates, the final closing date was May 7, 2015, and the archive date was June 7, 2015, indicating the application window for this specific announcement has ended.
What does it mean that the announcement is archived?
The archive date (June 7, 2015) indicates the announcement is maintained as a historical record and is no longer in an active application period under that specific FOA.
Where can applicants find full application instructions and requirements?
The description indicates that full details such as application instructions, review criteria, budgeting guidelines, and STTR partnership requirements would be available on the archived NIH funding announcement page referenced in the additional information link.
Who should be contacted for access or technical issues related to the online announcement?
For difficulties accessing the full announcement or problems linking to the funding notice, the point of contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What kinds of later-stage milestones are projects expected to be positioned for?
Projects are expected to mature toward a prototype or technology platform that is realistically positioned for later-stage testing, regulatory planning, and eventual clinical use.
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Applicants who have applied for this opportunity (PA 12 190) also looked into and applied for these:
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