Opportunity Information: Apply for PAR 16 326

  • The HHS-NIH11 in the education, environment, health sector is offering a public funding opportunity titled "Advancing Basic Behavioral and Social Research on Resilience: An Integrative Science Approach (UG3/UH3)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.213, 93.242, 93.273, 93.279, 93.399, 93.846, 93.866,.
  • This funding opportunity was created on Jun 13, 2016 and posted on Jun 13, 2016.
  • Applicants must submit their applications by Dec 01, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $250,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for PAR 16 326

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Opportunity Summary:

Advancing Basic Behavioral and Social Research on Resilience: An Integrative Science Approach (UG3/UH3) (PAR-16-326) is a National Institutes of Health (NIH) funding opportunity that supports basic behavioral and social science research aimed at explaining how resilience works. The central purpose is not simply to describe who is resilient, but to uncover the underlying mechanisms and processes that produce resilient functioning, especially as those processes unfold dynamically. The opportunity explicitly pushes applicants to treat resilience as something that changes over time and depends on interactions across multiple levels of analysis, rather than as a fixed trait or a single outcome.

A defining feature of this opportunity is its integrative scientific framework. Applications are expected to address resilience in ways that capture dynamics and interactions across time and scale, meaning research designs should be capable of examining how resilience-related processes operate moment-to-moment, over developmental periods, and across longer time frames as circumstances change. In addition, the FOA encourages work that spans multiple contexts (for example, different environments, settings, or life circumstances), multiple outcomes (such as mental health, physical health, social functioning, educational or occupational functioning), and multiple time frames. In practical terms, the research should be positioned to explain how resilient outcomes emerge from interacting influences rather than from any single factor in isolation.

The funding mechanism is a cooperative agreement using the UG3/UH3 phased innovation structure. That generally means projects begin with a milestone-driven planning or development phase (UG3) and, if prespecified milestones are met, can transition to an implementation phase (UH3). This structure is typically used when a project requires early-stage refinement, integration of complex components, or proof that the proposed approach is feasible before scaling up. Because it is a cooperative agreement, NIH staff are expected to have substantial programmatic involvement compared with a standard grant, which often translates into closer coordination around milestones, data approaches, and overall project direction.

From an administrative standpoint, the opportunity falls under a discretionary category and is tied to NIH within the U.S. Department of Health and Human Services (listed as HHS-NIH11). The activity areas connected to the listing include education, environment, and health, reflecting the broad relevance of resilience research to both health outcomes and the social and environmental conditions that shape them. The FOA references multiple CFDA numbers (93.113, 93.213, 93.242, 93.273, 93.279, 93.399, 93.846, 93.866), which signals that multiple NIH institutes or programs may have an interest in the topic and that the work may align with several NIH funding portfolios.

Eligibility is broad and includes many organization types that commonly participate in federally funded research. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized tribal governments; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education in those categories); for-profit organizations other than small businesses; small businesses; and other entities as described in the FOA’s additional eligibility language. This breadth suggests NIH’s intent to encourage participation from academic, governmental, community-linked, and potentially industry-associated research teams, provided the proposed science is rigorous and aligned with the integrative resilience framework.

Key dates provided for this specific posting indicate it was created and posted on June 13, 2016, with an application closing date of December 1, 2016 (both original and current closing dates match). The award ceiling listed is $250,000, which indicates an upper limit referenced in the opportunity summary; in practice, applicants typically need to align budgets with NIH policy, the specific instructions in the FOA, and the scope and phase of the UG3/UH3 project. The synopsis also lists “ExpectedAwards:” without a number, meaning the publicly summarized record does not specify how many awards NIH anticipated making from this announcement.

Overall, this opportunity is designed for research teams that can build and test explanatory models of resilience using methods that capture change over time, cross-level interactions, and the influence of varying contexts. Strong applications would typically be those that move beyond static correlations and instead articulate how resilience-related mechanisms operate, how they interact, and how they lead to different outcomes across different situations and time horizons, with a clear plan for meeting phased milestones under the UG3/UH3 cooperative agreement structure.

Frequently Asked Questions (FAQs)

What is the name and number of this funding opportunity?

The opportunity is titled Advancing Basic Behavioral and Social Research on Resilience: An Integrative Science Approach (UG3/UH3) and is identified as PAR-16-326.

Which agency is offering this grant?

This is a National Institutes of Health (NIH) funding opportunity within the U.S. Department of Health and Human Services (listed as HHS-NIH11).

What is the main purpose of this opportunity?

The central purpose is to support basic behavioral and social science research aimed at explaining how resilience works. The emphasis is not just on identifying who is resilient, but on uncovering the mechanisms and processes that produce resilient functioning.

Does this FOA focus on resilience as a trait or as something dynamic?

This FOA explicitly pushes applicants to treat resilience as dynamic, meaning it changes over time and depends on interactions across multiple levels of analysis, rather than being treated as a fixed trait or a single outcome.

What does an "integrative science approach" mean in this announcement?

Applications are expected to address resilience in ways that capture dynamics and interactions across time and scale. That includes examining how resilience-related processes unfold moment-to-moment, across developmental periods, and over longer time frames as circumstances change.

What kinds of research designs does NIH seem to be encouraging here?

The announcement encourages research designs that can explain how resilient outcomes emerge from interacting influences rather than from any single factor in isolation. It also encourages work that spans multiple contexts, multiple outcomes, and multiple time frames.

What types of outcomes are mentioned as examples that could be included?

Examples of outcomes mentioned include mental health, physical health, social functioning, and educational or occupational functioning.

Does the opportunity encourage studying resilience across different contexts?

Yes. The FOA encourages work that spans multiple contexts, such as different environments, settings, or life circumstances, to better explain how resilience-related processes operate under varying conditions.

What is the funding mechanism used for this program?

The mechanism is a cooperative agreement using the UG3/UH3 phased innovation structure.

What does the UG3/UH3 phased structure mean in practical terms?

Projects generally begin with a milestone-driven planning or development phase (UG3). If prespecified milestones are met, the project can transition to an implementation phase (UH3). This structure is often used when early refinement, integration of complex components, or feasibility proof is needed before scaling up.

How is a cooperative agreement different from a standard NIH grant?

Because this is a cooperative agreement, NIH staff are expected to have substantial programmatic involvement compared with a standard grant. This often translates into closer coordination around milestones, data approaches, and overall project direction.

What are the key dates listed for this opportunity?

The posting indicates it was created and posted on June 13, 2016, and the application closing date is December 1, 2016 (the original and current closing dates match).

What is the award ceiling listed in the opportunity summary?

The summary lists an award ceiling of $250,000, described as an upper limit referenced in the opportunity summary.

Does the posting specify how many awards NIH expects to make?

The synopsis shows "ExpectedAwards:" without a number, meaning the publicly summarized record does not specify how many awards NIH anticipated making from this announcement.

What activity areas are associated with this listing?

The activity areas connected to the listing include education, environment, and health, reflecting the broad relevance of resilience research to health outcomes and to social and environmental conditions.

What CFDA numbers are referenced, and what does that imply?

The FOA references multiple CFDA numbers: 93.113, 93.213, 93.242, 93.273, 93.279, 93.399, 93.846, 93.866. This signals that multiple NIH institutes or programs may have an interest in the topic and that the work may align with several NIH funding portfolios.

Who is eligible to apply for this opportunity?

Eligibility is broad. Eligible applicants include:

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • Federally recognized Native American tribal governments
  • Native American tribal organizations (not federally recognized tribal governments)
  • Public housing authorities and Indian housing authorities
  • Nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education in those categories)
  • For-profit organizations other than small businesses
  • Small businesses
  • Other entities as described in the FOA's additional eligibility language

Does this opportunity appear limited to universities and academic medical centers?

No. The eligibility language includes many organization types beyond higher education, including government entities, tribal governments and organizations, nonprofits, public housing authorities, and for-profit organizations (including small businesses), as long as the proposed science fits the FOA.

What kinds of teams or projects seem best aligned with this FOA?

This opportunity is designed for teams that can build and test explanatory models of resilience using methods that capture change over time, cross-level interactions, and the influence of varying contexts, along with a clear plan for meeting phased milestones under the UG3/UH3 structure.

What type of research is emphasized: descriptive studies or mechanism-focused studies?

The FOA emphasizes mechanism- and process-focused research aimed at explaining how resilience-related mechanisms operate and interact to produce outcomes over time, rather than focusing only on static descriptions or correlations.

What administrative category is this opportunity listed under?

The opportunity is listed under a discretionary category.

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