Opportunity Information: Apply for RFA DA 16 001
Apply for RFA DA 16 001
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Advancing Exceptional Research on HIV/AIDS and Substance Abuse (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Feb 10, 2015 and posted on Feb 10, 2015.
- Applicants must submit their applications by Jul 31, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Private institutions of higher education Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) State governments County governments Independent school districts.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
Advancing Exceptional Research on HIV/AIDS and Substance Abuse (R01) (Funding Opportunity Number RFA-DA-16-001) is a discretionary NIH grant opportunity that sought to fund highly innovative research projects at the intersection of HIV/AIDS and substance use. The purpose of the announcement was to push the field beyond incremental advances by supporting R01 studies that could open entirely new directions in HIV research and/or generate fresh approaches to prevention and treatment for people who use drugs or have substance use disorders. A central expectation is that the connection to substance abuse is not incidental; applicants are expected to clearly and explicitly describe the HIV-substance use nexus that motivates the project and makes it uniquely responsive to the goals of the program.
This opportunity was positioned as a complement to the NIH Avant Garde Award Program in HIV/AIDS research. The key distinction highlighted in the announcement is that, unlike the Avant Garde mechanism (which is geared toward high-risk, high-reward investigators and does not require a detailed research plan), this R01 FOA required a traditional, detailed research plan along with preliminary data. In practical terms, that means applicants needed to demonstrate not only a bold idea, but also credible feasibility and a well-developed approach, including clear aims, methods, analytic strategy, and supporting evidence that the work is ready to be carried out within an R01 framework.
The scientific scope was intentionally broad. The FOA did not restrict applications to a particular discipline, population, or stage of the HIV care continuum, as long as the proposed work was innovative and meaningfully tied to drug abuse. Projects could be proposed by individual investigators or by multidisciplinary teams, allowing applicants to assemble expertise across basic science, clinical research, behavioral science, implementation science, epidemiology, intervention development, or other relevant areas. The unifying theme was innovation with the potential for real conceptual or practical payoff in preventing HIV acquisition, improving treatment outcomes, or otherwise reducing HIV burden specifically among substance-using populations.
From an administrative standpoint, the funding instrument was a grant using the R01 mechanism, under the NIH umbrella and associated with CFDA 93.279 (Drug Abuse and Addiction Research Programs). The announcement listed an estimated total funding amount of $2,000,000 and specified that there was no cost sharing or matching requirement. The FOA was posted February 10, 2015, with an original and current closing date of July 31, 2015, and an archive date of August 31, 2015, indicating it was a time-limited solicitation for that cycle.
Eligibility was broad and included many common applicant types across academia, government, nonprofits, and industry. Eligible applicants included private and public institutions of higher education, small businesses, for-profit organizations (including those other than small businesses), and nonprofits both with and without 501(c)(3) status. Government entities at multiple levels were also eligible, including state, county, city/township governments, independent school districts, special district governments, and public housing authorities/Indian housing authorities. The eligibility section also explicitly included a wide range of mission- or population-focused institutions and organizations, such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and AANAPISIs, along with faith-based or community-based organizations, U.S. territories or possessions, and regional organizations. It further noted eligibility for certain tribal governments and tribal organizations, and it allowed non-U.S. entities (foreign organizations), reflecting an openness to research capacity wherever it is strongest and most relevant to the public health problem.
For reference and official details, the announcement pointed applicants to the NIH funding notice page (http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-16-001.html). It also provided contact guidance through the NIH Office of Extramural Research webmaster for access or linking issues (FBOWebmaster@OD.NIH.GOV).
Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
The opportunity is titled "Advancing Exceptional Research on HIV/AIDS and Substance Abuse (R01)." The Funding Opportunity Number (FOA) is RFA-DA-16-001.
Which agency offered this funding opportunity?
This is an NIH (National Institutes of Health) discretionary grant opportunity under the NIH umbrella.
What type of grant mechanism does this opportunity use?
The funding instrument is a grant using the NIH R01 mechanism.
What is the overall purpose of the FOA?
The purpose was to fund highly innovative research projects at the intersection of HIV/AIDS and substance use, specifically aiming to push the field beyond incremental advances and open new directions in HIV research and/or create fresh approaches to prevention and treatment for people who use drugs or have substance use disorders.
What does the FOA mean by the HIV-substance use “nexus” needing to be explicit?
A central expectation is that the substance use connection cannot be incidental. Applicants were expected to clearly and explicitly describe how and why the project is motivated by the HIV-substance use relationship and how that makes the application uniquely responsive to the program goals.
How is this FOA different from the NIH Avant Garde Award Program?
This FOA was described as a complement to the NIH Avant Garde Award Program in HIV/AIDS research. The key distinction highlighted is that, unlike the Avant Garde mechanism (which is geared toward high-risk, high-reward investigators and does not require a detailed research plan), this R01 FOA required a traditional, detailed research plan and preliminary data.
Did applicants need to include a detailed research plan?
Yes. The FOA required a traditional, detailed research plan, including clear aims, methods, an analytic strategy, and supporting evidence showing the work was ready to be conducted within an R01 framework.
Was preliminary data required?
Yes. The announcement specifically noted that preliminary data were required, reflecting an expectation of feasibility alongside innovation.
How broad was the scientific scope?
The scope was intentionally broad. The FOA did not restrict applications to a particular discipline, population, or stage of the HIV care continuum, as long as the proposed work was innovative and meaningfully tied to drug abuse.
What kinds of research approaches could be proposed?
Projects could involve expertise spanning basic science, clinical research, behavioral science, implementation science, epidemiology, intervention development, or other relevant areas. The unifying theme was innovation with potential conceptual or practical payoff in preventing HIV acquisition, improving treatment outcomes, or reducing HIV burden specifically among substance-using populations.
Could projects be led by an individual investigator or a team?
Yes. The FOA allowed projects proposed by individual investigators or by multidisciplinary teams.
What program or CFDA listing is associated with this FOA?
The FOA is associated with CFDA 93.279, Drug Abuse and Addiction Research Programs.
How much funding was estimated to be available?
The announcement listed an estimated total funding amount of $2,000,000.
Was cost sharing or matching required?
No. The FOA specified there was no cost sharing or matching requirement.
When was the FOA posted?
The FOA was posted on February 10, 2015.
What was the application closing date?
The original and current closing date listed in the announcement was July 31, 2015.
Is this FOA still active?
The announcement included an archive date of August 31, 2015, indicating it was a time-limited solicitation for that cycle.
Who was eligible to apply?
Eligibility was broad and included many applicant types across academia, government, nonprofits, and industry. Eligible applicants included private and public institutions of higher education, small businesses, for-profit organizations (including those other than small businesses), and nonprofits both with and without 501(c)(3) status.
Were government entities eligible to apply?
Yes. Government entities at multiple levels were eligible, including state, county, city/township governments, independent school districts, special district governments, and public housing authorities/Indian housing authorities.
Were mission- or population-focused institutions explicitly included?
Yes. The eligibility section explicitly included institutions and organizations such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and AANAPISIs. It also included faith-based or community-based organizations, U.S. territories or possessions, and regional organizations.
Could tribal governments or tribal organizations apply?
Yes. The FOA noted eligibility for certain tribal governments and tribal organizations.
Were non-U.S. (foreign) organizations eligible?
Yes. The FOA allowed non-U.S. entities (foreign organizations), reflecting openness to research capacity wherever it is strongest and most relevant to the public health problem.
Where can applicants find the official FOA notice?
The announcement directed applicants to the NIH funding notice page: http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-16-001.html
Who should be contacted for access or linking issues related to the FOA page?
The announcement provided contact guidance through the NIH Office of Extramural Research webmaster for access or linking issues: FBOWebmaster@OD.NIH.GOV
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