Opportunity Information: Apply for DFOP0017890
Apply for DFOP0017890
- The Bureau of Global Health Security and Diplomacy in the health sector is offering a public funding opportunity titled "Advancing Global Health" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 19.029.
- This funding opportunity was created on 2026-03-05.
- Applicants must submit their applications by 2027-02-14.
- Each selected applicant is eligible to receive up to $250,000,000.00 in funding.
- The number of recipients for this funding is limited to 100 candidate(s).
- Eligible applicants include: Unrestricted.
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Opportunity Summary:
The U.S. Department of State, through the Bureau of Global Health Security and Diplomacy (GHSD), is offering a discretionary grant opportunity called "Advancing Global Health" (Funding Opportunity Number DFOP0017890, CFDA 19.029). The opportunity is structured as an Annual Program Statement (APS), meaning it is designed as an umbrella framework that the Department can use over time to identify and fund a range of projects that support U.S. global health priorities rather than a single, one-time program with one fixed scope. The overall intent is to advance the America First Global Health Strategy by focusing on practical outcomes like saving lives, strengthening health systems, improving efficiency, encouraging partner-country self-reliance, and ensuring that U.S. investments also support American safety, strength, and prosperity.
A key feature of this APS is that it is meant to complement, extend, or fill gaps in efforts connected to bilateral Memoranda of Understanding (MOUs). Instead of prescribing one universal set of activities, the Department will release specific Addenda under this APS to signal what it wants to fund at any given time. Each Addendum functions like a targeted call that lays out particular priorities, needs, and thematic focus areas based on evolving conditions and on-the-ground realities. In practice, applicants should expect that the actionable details, such as what countries or issues are being prioritized and what types of interventions are most needed, will be spelled out in the relevant Addendum rather than in the broad APS language alone.
The application approach centers on submitting Statements of Interest (SOIs) in response to those Addenda. The APS provides the standard instructions that apply across submissions, including how SOIs should be prepared and what baseline requirements applicants must follow. Eligibility is listed as unrestricted at the summary level, but the notice emphasizes that applicants still need to consult the APS instructions for the full eligibility criteria and any additional conditions that may apply under a given Addendum. GHSD also notes it will coordinate with U.S. Embassies and other Department of State bureaus and offices to shape and publish these Addenda, which signals that projects are expected to align with diplomatic engagement and country-specific priorities, not just technical public health goals.
From a funding perspective, the opportunity indicates a very large potential scale, with an award ceiling up to $250,000,000 and an estimate of around 100 awards, suggesting that the Department anticipates supporting a mix of activities and potentially a wide range of award sizes depending on the Addendum. The opportunity’s original closing date is listed as February 14, 2027, which fits the APS model where proposals can be solicited and reviewed over an extended period as specific Addenda are released. Overall, this is best understood as a long-running vehicle for global health security and health systems-related projects, where the most important step for applicants is to track and respond to the relevant Addenda and follow the APS instructions closely when submitting an SOI.
Frequently Asked Questions (FAQs) - Advancing Global Health (DFOP0017890)
1) What is this funding opportunity?
This is a discretionary grant opportunity from the U.S. Department of State, Bureau of Global Health Security and Diplomacy (GHSD), titled "Advancing Global Health". The Funding Opportunity Number is DFOP0017890 and the CFDA listing is 19.029.
2) What does it mean that this opportunity is an Annual Program Statement (APS)?
An Annual Program Statement (APS) is an umbrella framework the Department can use over time to identify and fund a range of projects, rather than a single one-time program with one fixed scope. Under this APS, the Department plans to release specific Addenda over an extended period, and those Addenda will define what the Department is seeking to fund at a given time.
3) Is this a single program with one fixed set of activities?
No. The APS does not prescribe one universal set of activities. Instead, it sets baseline instructions and requirements, while the actionable priorities and requested activities are expected to be specified in the relevant Addendum.
4) What is the overall purpose of the APS?
The intent is to advance the America First Global Health Strategy by focusing on practical outcomes such as saving lives, strengthening health systems, improving efficiency, encouraging partner-country self-reliance, and ensuring U.S. investments support American safety, strength, and prosperity.
5) How does this APS relate to Memoranda of Understanding (MOUs)?
A key feature of this APS is that it is meant to complement, extend, or fill gaps in efforts connected to bilateral MOUs. Projects supported under the APS are intended to connect to or strengthen ongoing MOU-related efforts rather than operate in isolation.
6) Where will the specific priorities and focus areas be defined?
The Department will release Addenda under this APS. Each Addendum functions like a targeted call that lays out particular priorities, needs, and thematic focus areas based on evolving conditions and on-the-ground realities. Applicants should rely on the relevant Addendum for details such as prioritized countries, issues, and types of interventions.
7) What should applicants submit to apply?
The application approach centers on submitting Statements of Interest (SOIs) in response to the Addenda released under the APS.
8) Do I apply directly to the APS, or do I apply to an Addendum?
The APS provides the standing framework and instructions, but submissions are made as SOIs responding to specific Addenda. In practice, the Addendum is what signals what GHSD wants to fund at that time, and the APS supplies the standard requirements that apply across submissions.
9) What instructions should I follow when preparing an SOI?
The APS provides the standard instructions that apply across submissions, including how SOIs should be prepared and what baseline requirements applicants must follow. The relevant Addendum will provide the targeted priorities and any additional context tied to current needs.
10) Who is eligible to apply?
Eligibility is listed as unrestricted at the summary level. However, the notice emphasizes that applicants must consult the APS instructions for the full eligibility criteria and should also check whether a specific Addendum includes additional conditions or requirements.
11) Will GHSD coordinate with U.S. Embassies or other parts of the Department of State?
Yes. GHSD notes it will coordinate with U.S. Embassies and other Department of State bureaus and offices to shape and publish Addenda. This signals that projects are expected to align with diplomatic engagement and country-specific priorities, not only technical public health goals.
12) What kinds of results is the Department looking for?
Based on the APS intent, the Department is looking for practical outcomes that align with U.S. global health priorities, including saving lives, strengthening health systems, improving efficiency, encouraging partner-country self-reliance, and supporting American safety, strength, and prosperity.
13) How much funding is available?
The opportunity indicates a very large potential scale, with an award ceiling up to $250,000,000. The notice also estimates around 100 awards, suggesting a potential mix of activities and award sizes depending on the specific Addendum.
14) How many awards does the Department expect to make?
The opportunity estimates approximately 100 awards, which suggests multiple projects may be supported over time, potentially across different themes, countries, or needs identified in Addenda.
15) What does the award ceiling mean for applicants?
The stated ceiling (up to $250,000,000) reflects the maximum possible award amount under this opportunity. Actual award sizes may vary widely and are expected to depend on what a specific Addendum is seeking to fund.
16) What is the closing date for this opportunity?
The original closing date is listed as February 14, 2027. This aligns with the APS model, where proposals can be solicited and reviewed over an extended period as different Addenda are released.
17) Does the 2027 closing date mean I can submit anytime?
The APS is designed to run over a longer period, but the key submission triggers are the Addenda. Applicants should expect that SOIs are submitted in response to specific Addenda, which may have their own timing and priorities based on evolving needs.
18) What is the most important step for an applicant interested in this APS?
The most important step is to track and respond to relevant Addenda and follow the APS instructions closely when preparing and submitting a Statement of Interest (SOI).
19) Where will country priorities and on-the-ground needs be reflected?
The APS indicates that Addenda will be shaped based on evolving conditions and realities, and GHSD will coordinate with U.S. Embassies and other State Department offices. As a result, the country priorities and in-country needs are expected to be articulated in the relevant Addendum.
20) Is this opportunity primarily about global health security and health systems?
Yes. Overall, it is best understood as a long-running vehicle for global health security and health systems-related projects aligned with U.S. global health priorities, with specifics determined by Addenda released under the APS.
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