Opportunity Information: Apply for RFA MH 12 080
Apply for RFA MH 12 080
- The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Advancing HIV Prevention through Transformative Behavioral and Social Science Research (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Jun 21, 2011 and posted on Jun 21, 2011.
- Applicants must submit their applications by Jan 6, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $5,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Public housing authorities/Indian housing authorities Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education County governments For profit organizations other than small businesses Independent school districts Small businesses City or township governments State governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Advancing HIV Prevention through Transformative Behavioral and Social Science Research (R01) funding opportunity (RFA-MH-12-080) is a National Institutes of Health (NIH) discretionary grant program designed to support research that meaningfully strengthens HIV prevention in the United States. The central aim is to generate generalizable knowledge, meaning findings that extend beyond a single site or population and can inform broader HIV prevention strategies, policies, and programs. The opportunity is explicitly framed around the idea that major progress in HIV prevention depends on understanding not only biomedical tools and outcomes, but also the behavioral and social conditions that shape risk, prevention uptake, adherence, and long-term impact.
A defining feature of this FOA is its emphasis on truly integrative and "transformative" behavioral and social science. It treats behavioral and social research as essential partners to biomedical HIV prevention modalities rather than as add-ons. The announcement highlights a reciprocal relationship: social and behavioral methods and findings can improve the development, implementation, and effectiveness of biomedical prevention approaches, while biomedical perspectives and measures are also necessary to advance behavioral and social HIV prevention research. In practical terms, the FOA encourages comprehensive studies that account for how social, behavioral, and biomedical factors interact with each other, and it expects those interactions to be reflected in both study design and interpretation. Projects are expected to speak to real-world HIV prevention challenges in the domestic context, aligning with the goals of the National HIV/AIDS Strategy and focusing on issues that are highly relevant to the U.S. epidemic.
The mechanism used is the NIH R01, which generally supports substantial, hypothesis-driven research projects that can include observational, interventional, and mixed-methods designs, so long as they fit the FOA’s integrative behavioral-social-biomedical focus. The total estimated funding for the opportunity is about $5,000,000, and the award ceiling is listed as $500,000. There is no cost sharing or matching requirement, which reduces financial barriers for applicants and allows proposed budgets to be driven by scientific needs rather than required institutional contributions.
Eligibility is broad and includes many types of organizations that can credibly conduct HIV prevention research. Eligible applicants include public and private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), for-profit organizations (other than small businesses), small businesses, state and local governments, independent school districts, special district governments, public housing authorities/Indian housing authorities, and tribal governments and tribal organizations. The FOA also notes additional eligible applicants such as federal agencies, faith-based and community-based organizations, regional organizations, U.S. territories or possessions, and a range of institutions serving specific communities, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities (TCCUs). This wide eligibility reflects an understanding that HIV prevention research and implementation capacity often sits across academia, public health practice settings, and community-rooted organizations.
Administratively, the FOA was posted and created on June 21, 2011, with an original and current closing date of January 6, 2012, and it was archived on February 6, 2012. The activity spans multiple CFDA program areas, reflecting the cross-cutting nature of HIV prevention research, including mental health research grants (93.242), alcohol research programs (93.273), drug abuse and addiction research programs (93.279), microbiology and infectious diseases research (93.856), and child health and human development extramural research (93.865). For applicants needing the full details, NIH provided the full announcement link via the NIH Grants Guide, and technical help contacts were routed through the NIH Office of Extramural Research (OER) webmaster.
Frequently Asked Questions (FAQs)
What is the name of this funding opportunity?
The funding opportunity is titled Advancing HIV Prevention through Transformative Behavioral and Social Science Research (R01). The FOA number is RFA-MH-12-080.
Which federal agency is offering this grant?
This is a National Institutes of Health (NIH) discretionary grant program.
What is the main purpose of this FOA?
The central aim is to support research that meaningfully strengthens HIV prevention in the United States by generating generalizable knowledge that can inform broader HIV prevention strategies, policies, and programs.
What does "generalizable knowledge" mean in this FOA?
It refers to findings that extend beyond a single site or population and can be used to inform HIV prevention efforts more broadly (for example, across multiple settings, communities, or programs within the U.S.).
What makes this FOA different from other HIV prevention research opportunities?
A defining feature is its emphasis on integrative and "transformative" behavioral and social science research that is treated as an essential partner to biomedical HIV prevention approaches (not as an add-on). The FOA emphasizes studying how social, behavioral, and biomedical factors interact and expects that integration to show up in study design and interpretation.
Does this FOA focus only on biomedical HIV prevention tools?
No. The FOA is explicitly framed around the idea that major progress in HIV prevention depends on understanding behavioral and social conditions that shape risk, prevention uptake, adherence, and long-term impact, alongside biomedical tools and outcomes.
What kinds of research designs are supported under the R01 mechanism in this FOA?
The mechanism is NIH R01, which generally supports substantial, hypothesis-driven research projects. The FOA notes that projects may include observational, interventional, and mixed-methods designs, as long as they fit the FOA's integrative behavioral-social-biomedical focus.
Is the FOA focused on the United States or global HIV prevention?
The FOA is focused on HIV prevention challenges in the domestic U.S. context and highlights alignment with the goals of the National HIV/AIDS Strategy.
What is the total estimated funding amount for this opportunity?
The total estimated funding for the opportunity is approximately $5,000,000.
What is the award ceiling listed for this FOA?
The award ceiling is listed as $500,000.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad and includes:
- Public and private institutions of higher education
- Nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status)
- For-profit organizations (other than small businesses)
- Small businesses
- State and local governments
- Independent school districts
- Special district governments
- Public housing authorities/Indian housing authorities
- Tribal governments and tribal organizations
Are community-based or faith-based organizations eligible?
Yes. The FOA notes additional eligible applicants including faith-based and community-based organizations, as well as regional organizations.
Are federal agencies eligible to apply?
Yes. The FOA lists federal agencies among additional eligible applicants.
Are U.S. territories or possessions eligible to apply?
Yes. The FOA includes U.S. territories or possessions among additional eligible applicants.
Does the FOA highlight eligibility for institutions serving specific communities?
Yes. The FOA explicitly mentions a range of eligible institutions serving specific communities, including:
- Historically Black Colleges and Universities (HBCUs)
- Hispanic-serving institutions
- Alaska Native and Native Hawaiian-serving institutions
- Tribally Controlled Colleges and Universities (TCCUs)
When was this FOA posted and created?
The FOA was posted and created on June 21, 2011.
What was the application closing date?
The original and current closing date listed is January 6, 2012.
Is this funding opportunity still open?
No. The FOA was archived on February 6, 2012, and the listed closing date has passed.
What CFDA program areas are associated with this FOA?
The activity spans multiple CFDA program areas, reflecting the cross-cutting nature of the research focus, including:
- 93.242 Mental Health Research Grants
- 93.273 Alcohol Research Programs
- 93.279 Drug Abuse and Addiction Research Programs
- 93.856 Microbiology and Infectious Diseases Research
- 93.865 Child Health and Human Development Extramural Research
Where can applicants find the full announcement?
NIH provided the full announcement link via the NIH Grants Guide.
Where can applicants get technical help related to the announcement?
Technical help contacts were routed through the NIH Office of Extramural Research (OER) webmaster.
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