Opportunity Information: Apply for PAS 10 226
Apply for PAS 10 226
- The National Institutes of Health in the education environment food and nutrition health income security and social services sector is offering a public funding opportunity titled "Advancing Novel Science in Womens Health Research (ANSWHR) (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.307 Minority Health and Health Disparities Research 93.361 Nursing Research 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research 93.879 Medical Library Assistance 93.989 International Research and Research Training.
- This funding opportunity was created on Jul 1, 2010 and posted on Jul 1, 2010.
- Applicants must submit their applications by Jan 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Private institutions of higher education Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses State governments Public and State controlled institutions of higher education Special district governments Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Advancing Novel Science in Womens Health Research (ANSWHR) (R21) opportunity (Funding Opportunity Number PAS 10-226) is an NIH discretionary grant program led by the Office of Research on Womens Health (ORWH) with co-sponsorship from multiple NIH Institutes and Centers. Its central aim is to push forward innovative and interdisciplinary early-stage research that introduces new ideas, tools, or approaches in womens health and in the broader study of sex and gender differences. The announcement reflects a growing body of evidence showing that it is not enough to treat males and females as interchangeable in research. Instead, it highlights the scientific and clinical value of examining sex-based biological factors and gender-related influences, including the importance of analyzing data separately for females and males when appropriate. While ORWH specifically encourages proposals that explore how sex and gender factors shape health outcomes for women, the scope is intentionally broad and welcomes applications across essentially all areas of womens health and/or sex and gender research.
This FOA uses the NIH Exploratory/Developmental Grant mechanism (R21), which is designed for high-risk, high-reward projects that are still in an exploratory phase. In practical terms, that means the program is meant to help investigators test novel hypotheses, generate preliminary data, or establish proof-of-concept for unconventional or emerging lines of inquiry that may be too early for larger, more definitive grant mechanisms. The posted award ceiling is $200,000, consistent with the R21 program style of providing targeted support for development and early validation rather than full-scale implementation.
On funding levels, NIH anticipated making approximately $4 million available in fiscal year 2011 for awards under this announcement. The agency makes clear that both the total dollars awarded and the number of projects ultimately funded depend on congressional appropriations, the availability of funds at the time of award, and the volume, quality, and budget requests of submitted applications. In other words, awards are competitive and contingent, and the final portfolio will reflect which proposals are judged most meritorious through NIH peer review and programmatic decision-making.
Eligibility is broad and includes a wide range of organization types across the public, private, nonprofit, and for-profit sectors. Eligible applicants include public and state-controlled institutions of higher education and private universities, nonprofit organizations with or without 501(c)(3) status, small businesses, other for-profit organizations (beyond small businesses), independent school districts, and multiple levels of government such as city/township, county, state, special district governments, and public housing authorities/Indian housing authorities. The announcement also explicitly includes many mission-focused and capacity-building institution types, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and eligible federal agencies. Faith-based and community-based organizations are eligible as well. Importantly, it also allows non-domestic (non-U.S.) entities (foreign organizations), regional organizations, and U.S. territories or possessions, reflecting NIHs willingness to support relevant science wherever strong expertise and appropriate infrastructure exist. There is no cost-sharing or matching requirement, so applicants are not required to contribute non-federal funds as a condition of receiving an award.
In terms of research breadth, the listing of CFDA numbers signals that applications could align with many biomedical and behavioral health domains supported across NIH, including (among others) environmental health, oral health, genomics, communication disorders, complementary and integrative health, mental health, alcohol and substance use, minority health and health disparities, nursing research, cancer across the continuum, cardiovascular disease, diabetes and kidney disease, neuroscience, immunology and infectious disease, child health and development, aging, vision research, and international research and training. Taken together, those categories reinforce that ANSWHR is not restricted to a single disease area. Instead, it is meant to catalyze cross-cutting womens health and sex/gender-differences science wherever a novel, interdisciplinary approach could open up new directions or challenge existing assumptions.
Administratively, the opportunity was posted July 1, 2010, with an original (and final) closing date of January 7, 2013, and an archive date of February 7, 2013, indicating it is no longer active as a current open solicitation. The sponsoring agency is the National Institutes of Health. For applicants or interested parties who needed help accessing the full announcement when it was active, NIH provided support through the NIH Office of Extramural Research (OER) Webmaster (FBOWebmaster@OD.NIH.GOV) and included a link to the full FOA details hosted on the NIH grants website (http://grants.nih.gov/grants/guide/pa-files/PAS-10-226.html).
FAQs: Advancing Novel Science in Womens Health Research (ANSWHR) (R21) - PAS 10-226
What is the ANSWHR (R21) opportunity (PAS 10-226)?
Advancing Novel Science in Womens Health Research (ANSWHR) (R21) is an NIH discretionary grant opportunity led by the NIH Office of Research on Womens Health (ORWH) and co-sponsored by multiple NIH Institutes and Centers. It supports innovative, interdisciplinary early-stage research in womens health and in the broader study of sex and gender differences.
Which agency runs this funding opportunity?
The sponsoring agency is the National Institutes of Health (NIH). The program is led by the NIH Office of Research on Womens Health (ORWH), with co-sponsorship from multiple NIH Institutes and Centers.
What is the main goal of this program?
The central aim is to advance novel, high-impact early-stage research that brings forward new ideas, tools, or approaches for womens health and/or sex and gender differences research. The announcement emphasizes that males and females should not automatically be treated as interchangeable in research and highlights the value of examining sex-based biological factors and gender-related influences.
Does the program focus only on womens health conditions?
No. While ORWH encourages proposals that explore how sex and gender factors shape health outcomes for women, the scope is intentionally broad. Applications are welcomed across essentially all areas of womens health and/or sex and gender research, including cross-cutting and interdisciplinary projects.
What does the R21 mechanism mean for applicants?
This opportunity uses the NIH Exploratory/Developmental Grant mechanism (R21). It is designed for high-risk, high-reward projects that are exploratory. The intent is to help investigators test novel hypotheses, generate preliminary data, or establish proof-of-concept for emerging ideas that may be too early for larger, more definitive grant mechanisms.
What is the maximum award amount for this R21?
The posted award ceiling is $200,000, consistent with the R21 approach of providing targeted support for development and early validation rather than full-scale implementation.
How much total funding did NIH anticipate for this announcement?
NIH anticipated making approximately $4 million available in fiscal year 2011 for awards under this announcement.
Is funding guaranteed if an application is submitted?
No. NIH stated that the total dollars awarded and the number of projects funded depend on congressional appropriations, the availability of funds at the time of award, and the volume, quality, and budget requests of submitted applications. Awards are competitive and depend on peer review and programmatic decision-making.
What types of organizations were eligible to apply?
Eligibility was broad and included many organization types across the public, private, nonprofit, and for-profit sectors. Examples listed in the announcement include institutions of higher education (public/state-controlled and private), nonprofit organizations (with or without 501(c)(3) status), small businesses, other for-profit organizations, independent school districts, and multiple levels of government (city/township, county, state, special district governments, and public housing authorities/Indian housing authorities).
Were minority-serving and mission-focused institutions included in eligibility?
Yes. The announcement explicitly included institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and eligible federal agencies.
Were faith-based and community-based organizations eligible?
Yes. The opportunity states that faith-based and community-based organizations were eligible applicants.
Could non-U.S. organizations apply?
Yes. The announcement allowed non-domestic (non-U.S.) entities (foreign organizations), regional organizations, and U.S. territories or possessions to apply, reflecting NIH support for relevant science wherever appropriate expertise and infrastructure exist.
Was cost-sharing or matching required?
No. The opportunity specifies there was no cost-sharing or matching requirement. Applicants were not required to contribute non-federal funds as a condition of receiving an award.
What research areas could fit under this opportunity?
The scope was broad and aligned with many NIH-supported biomedical and behavioral health domains. The CFDA listings indicated potential alignment with areas including environmental health, oral health, genomics, communication disorders, complementary and integrative health, mental health, alcohol and substance use, minority health and health disparities, nursing research, cancer, cardiovascular disease, diabetes and kidney disease, neuroscience, immunology and infectious disease, child health and development, aging, vision research, and international research and training. Overall, ANSWHR was intended to catalyze womens health and sex/gender-differences science across many fields rather than focusing on one disease area.
What kinds of scientific considerations did the announcement emphasize?
The announcement highlighted the scientific and clinical value of examining sex-based biological factors and gender-related influences. It also noted the importance, when appropriate, of analyzing data separately for females and males rather than assuming results are interchangeable.
When was this funding opportunity posted and when did it close?
The opportunity was posted on July 1, 2010. The original (and final) closing date was January 7, 2013, and the archive date was February 7, 2013.
Is PAS 10-226 still open for applications?
No. Based on the listed closing and archive dates, it is no longer active as a current open solicitation.
Where could applicants find the full FOA details (when it was active)?
NIH hosted the full Funding Opportunity Announcement on the NIH grants website at http://grants.nih.gov/grants/guide/pa-files/PAS-10-226.html.
Who was the listed contact for technical help accessing the announcement?
NIH provided support through the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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