Opportunity Information: Apply for RFA NR 10 007

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Advancing Palliative Care Research for Children Facing Life Limiting Conditions (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361 Nursing Research.
  • This funding opportunity was created on Feb 25, 2010 and posted on Feb 25, 2010.
  • Applicants must submit their applications by May 17, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $750,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Special district governments Private institutions of higher education Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments County governments City or township governments For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Native American tribal governments (Federally recognized).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The National Institute of Nursing Research (NINR) at the National Institutes of Health released this Funding Opportunity Announcement (FOA), RFA-NR-10-007, titled "Advancing Palliative Care Research for Children Facing Life Limiting Conditions (R21)," to support early-stage, high-impact biobehavioral research focused on pediatric palliative and end-of-life care. The central aim is to generate new knowledge and practical approaches that reduce suffering and improve quality of life for children who are living with life-limiting conditions, with explicit inclusion of infants and neonates, as well as support for their parents and families. The announcement emphasizes studies that address not only serious illness trajectories but also the aftereffects and long-term consequences of accidents that create life-limiting circumstances, reflecting a broad view of pediatric palliative needs across diagnoses and events.

The FOA is designed to encourage innovative research designs and methods that can quickly inform real-world pediatric palliative care practice. NINR highlights intervention-focused work, especially projects built by cross-disciplinary teams that can integrate perspectives from nursing, medicine, psychology, social work, ethics, rehabilitation, communication science, and related fields. In practical terms, the opportunity is looking for research that tests or pilots interventions and strategies with a clear line of sight to translation into clinical or community settings, rather than purely descriptive studies. Alongside symptom and distress reduction, the FOA also welcomes projects that help children cope with bereavement or anticipatory grief, including situations involving the loss or potential loss of a parent or other significant person in the child's life.

This opportunity uses the NIH R21 mechanism, which typically supports exploratory and developmental projects that may involve novel concepts, early testing of interventions, pilot studies, feasibility work, or development of new approaches that can later scale into larger trials. The R21 structure signals that NINR is prioritizing innovation and rapid learning, including research that can establish proof-of-concept, refine measures, and generate preliminary data to support subsequent R01-level studies. The FOA also notes that it runs in parallel with a companion announcement of the same scientific scope under the R01 mechanism (RFA-NR-10-006), which is geared toward more mature projects that are ready for larger-scale execution.

For fiscal year 2010, NINR committed an estimated total of $750,000 to this R21 FOA and anticipated making roughly 2 to 3 awards. The award ceiling listed is $200,000, indicating that proposed budgets were expected to fit within that upper limit. There is no cost sharing or matching requirement, which is consistent with many NIH research grant programs and reduces barriers for applicants who may not have access to non-federal matching funds.

Eligibility is intentionally broad and includes many types of organizations and institutions, such as public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), for-profit organizations (other than small businesses), small businesses, and a wide range of government entities (state, county, city/township, special district governments, independent school districts, and public housing authorities/Indian housing authorities). It also explicitly includes federally recognized tribal governments and other tribal organizations, along with various mission-driven and federally recognized institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribal Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and U.S. territories or possessions. Faith-based and community-based organizations are also listed as eligible, reinforcing the program's openness to community-anchored palliative care research and intervention delivery models.

From an administrative standpoint, the FOA was posted on February 25, 2010, with an original and current closing date of May 17, 2010, and an archive date of June 17, 2010. The CFDA number associated with this program is 93.361 (Nursing Research), and the activity category is listed under education and health, reflecting its placement within NIH's broader health research mission and NINR's focus on symptom science and quality-of-life outcomes. The official announcement link is provided through the NIH Grants Guide, and technical access issues were routed to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.

FAQs: RFA-NR-10-007 - Advancing Palliative Care Research for Children Facing Life Limiting Conditions (R21)

What is this funding opportunity?

This is a National Institutes of Health (NIH) Funding Opportunity Announcement (FOA) from the National Institute of Nursing Research (NINR). It is titled "Advancing Palliative Care Research for Children Facing Life Limiting Conditions (R21)" and is identified as RFA-NR-10-007.

What is the main purpose of the FOA?

The central aim is to support early-stage, high-impact biobehavioral research in pediatric palliative and end-of-life care. The goal is to generate new knowledge and practical approaches that reduce suffering and improve quality of life for children living with life-limiting conditions, while also supporting their parents and families.

What type of research does NINR want to fund under this FOA?

The FOA emphasizes innovative, intervention-focused research that can quickly inform real-world pediatric palliative care practice. It encourages exploratory and developmental projects such as early testing of interventions, pilot studies, feasibility studies, and development of new approaches that can later scale into larger trials.

Is this FOA focused on interventions or descriptive studies?

It is primarily oriented toward testing or piloting interventions and strategies with a clear path to translation into clinical or community settings, rather than purely descriptive studies.

What populations are explicitly included?

The FOA explicitly includes children facing life-limiting conditions, including infants and neonates. It also includes attention to parents and families as part of the pediatric palliative care context.

Does the FOA include situations beyond chronic or progressive illnesses?

Yes. The announcement highlights a broad view of pediatric palliative needs, including research that addresses not only serious illness trajectories but also the aftereffects and long-term consequences of accidents that create life-limiting circumstances.

Are grief and bereavement topics within scope?

Yes. In addition to symptom and distress reduction, the FOA welcomes projects that help children cope with bereavement or anticipatory grief, including situations involving the loss or potential loss of a parent or other significant person in the child's life.

What kind of research teams does NINR encourage?

The FOA encourages cross-disciplinary teams that integrate perspectives from areas such as nursing, medicine, psychology, social work, ethics, rehabilitation, and communication science, among related fields.

What funding mechanism is used?

This opportunity uses the NIH R21 mechanism, which typically supports exploratory and developmental research projects.

What does the R21 mechanism signal about project maturity?

The R21 structure signals a focus on innovation and rapid learning, including proof-of-concept work, refinement of measures, feasibility testing, and generation of preliminary data that can support later, larger studies (for example, R01-level projects).

Is there a related or companion funding opportunity?

Yes. The FOA notes a companion announcement with the same scientific scope under the R01 mechanism (RFA-NR-10-006), intended for more mature projects ready for larger-scale execution.

How much funding is available under this FOA (FY 2010)?

For fiscal year 2010, NINR committed an estimated total of $750,000 for this R21 FOA.

How many awards were anticipated?

NINR anticipated making approximately 2 to 3 awards under this FOA.

What is the award ceiling mentioned in the announcement?

The award ceiling listed is $200,000, indicating proposed budgets were expected to fit within that upper limit.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement.

Who is eligible to apply?

Eligibility is broad and includes public and private institutions of higher education; nonprofit organizations (both 501(c)(3) and non-501(c)(3)); for-profit organizations (other than small businesses); small businesses; and many government entities (state, county, city/township, special district governments, independent school districts, and public housing authorities/Indian housing authorities).

Are tribal governments and tribal organizations eligible?

Yes. The FOA explicitly includes federally recognized tribal governments and other tribal organizations.

Are minority-serving institutions and U.S. territories included in eligibility?

Yes. The FOA explicitly lists HBCUs, Hispanic-serving Institutions, Tribal Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and U.S. territories or possessions as eligible.

Are faith-based and community-based organizations eligible?

Yes. Faith-based and community-based organizations are listed as eligible, supporting community-anchored palliative care research and intervention delivery models.

When was the FOA posted?

The FOA was posted on February 25, 2010.

What was the closing date for applications?

The original and current closing date listed in the FOA is May 17, 2010.

When was the FOA archived?

The archive date listed is June 17, 2010.

What is the CFDA number for this program?

The CFDA number associated with this program is 93.361 (Nursing Research).

What activity category is this FOA listed under?

The FOA is listed under education and health.

Where was the official announcement posted?

The official announcement link is provided through the NIH Grants Guide.

Who should be contacted for technical access issues related to the FOA notice?

The FOA indicates that technical access issues were routed to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.

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