Opportunity Information: Apply for PA 14 002

  • The Agency for Health Care Research and Quality in the health sector is offering a public funding opportunity titled "Advancing Patient Safety Implementation through Safe Medication Use Research (R18)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.226 Research on Healthcare Costs, Quality and Outcomes.
  • This funding opportunity was created on Nov 14, 2013 and posted on Nov 14, 2013.
  • Applicants must submit their applications by Sep 25, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • Eligible applicants include: County governments State governments Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education.
  • Other Eligible Applicants include the following Eligible Agencies of the Federal Government Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply.
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Opportunity Summary:

Advancing Patient Safety Implementation through Safe Medication Use Research (R18) is a discretionary grant opportunity from the Agency for Healthcare Research and Quality (AHRQ) focused on reducing patient harm linked to medications by improving how medications are used across the entire health care system. The central idea is that medication safety problems are rarely caused by a single mistake; they often stem from breakdowns in a larger process that includes prescribing, transcribing, dispensing, administering, monitoring, and patient use and adherence. This program supports research that looks closely at those real-world workflows and tests practical, system-level changes that make medication use safer while also improving overall care delivery.

The opportunity sits within AHRQs Patient Safety (PS) Portfolio and emphasizes implementation-oriented research, meaning projects are expected to do more than describe a problem. The goal is to produce evidence about how to put proven or promising medication safety practices into routine use, how to make them work across different settings, and how to sustain them over time. AHRQ frames medication safety as a team responsibility and strongly encourages involvement from everyone who touches the medication-use process, including patients and families as active partners. It also highlights participation from nurses, pharmacists, pharmacy and medication administration technicians, physicians, health care administrators, and risk managers, reflecting an expectation that funded work will be grounded in the realities of clinical operations rather than isolated in a single discipline.

A key feature of this announcement is its broad view of where medication safety happens. It explicitly includes all settings of care, including care delivered in the home. That matters because many medication-related harms occur during transitions (for example, hospital discharge to home, or specialist to primary care), and because patients and caregivers often manage complex medication regimens outside formal clinical environments. Projects under this opportunity are therefore aligned with research that addresses handoffs, reconciliation, patient education, monitoring, communication, and the design of safer systems that follow the patient rather than staying confined to one facility or department.

From an administrative standpoint, the funding opportunity number is PA-14-002, and the program uses the R18 grant mechanism, which AHRQ commonly uses for larger, applied research and demonstration projects in health services and patient safety. The funding activity category is Health, and the relevant CFDA listing is 93.226 (Research on Healthcare Costs, Quality and Outcomes). The posted and creation date were November 14, 2013. The original and current closing date listed is September 25, 2016, with an archive date of October 26, 2016, meaning the specific announcement is no longer open but remains useful as a reference point for the types of projects AHRQ has sought in medication safety implementation research.

The award ceiling listed is $500,000, and there is no cost sharing or matching requirement, which can lower barriers for organizations that do not have discretionary funds to contribute. Eligibility is fairly broad and includes state governments, county governments, and city or township governments, as well as public and state-controlled institutions of higher education and private institutions of higher education. Federally recognized Native American tribal governments are eligible, and the announcement also notes eligibility for Native American tribal organizations other than federally recognized tribal governments, along with eligible federal government agencies (as described in the full announcement). Non-U.S. entities (foreign institutions) are not eligible to apply, which positions the program squarely around U.S.-based health system improvement and implementation contexts.

For applicants or readers trying to locate the full text, the announcement points to the NIH grants guide page for PA-14-002 and provides NIH Office of Extramural Research (OER) webmaster contact information for access or linking issues. Overall, the opportunity is best understood as support for applied, team-based, real-world research that makes medication use safer by improving the systems and processes that move medications through care settings and into patients hands, with a strong emphasis on implementation, cross-setting coordination, and meaningful engagement of both health professionals and patients and families.

FAQs: Advancing Patient Safety Implementation through Safe Medication Use Research (R18) - AHRQ (PA-14-002)

What is the name of this grant opportunity?

The opportunity is called Advancing Patient Safety Implementation through Safe Medication Use Research (R18).

Which agency is offering this funding opportunity?

This is a discretionary grant opportunity from the Agency for Healthcare Research and Quality (AHRQ).

What is the main purpose of the program?

The program focuses on reducing patient harm linked to medications by improving how medications are used across the health care system. It supports research that examines real-world medication-use workflows and tests practical, system-level changes to make medication use safer while improving care delivery.

What kinds of medication safety problems is AHRQ trying to address?

AHRQ emphasizes that medication safety problems are rarely caused by a single error. Instead, harms often come from breakdowns across a broader process that can include prescribing, transcribing, dispensing, administering, monitoring, and patient use/adherence.

What does AHRQ mean by "implementation-oriented" research in this program?

Implementation-oriented research is expected to go beyond describing a problem. Projects should produce evidence about how to put proven or promising medication safety practices into routine use, how to make them work across different settings, and how to sustain them over time.

What AHRQ portfolio does this opportunity fall under?

This opportunity sits within AHRQ's Patient Safety (PS) Portfolio.

What grant mechanism is used for this opportunity?

The program uses the R18 grant mechanism, which AHRQ commonly uses for larger, applied research and demonstration projects in health services and patient safety.

What is the funding opportunity number?

The funding opportunity number is PA-14-002.

What is the activity category and CFDA listing?

The funding activity category is Health. The relevant CFDA listing is 93.226 (Research on Healthcare Costs, Quality and Outcomes).

How much funding is available per award?

The listed award ceiling is $500,000.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement.

Which care settings are included in the program's scope?

The announcement takes a broad view of medication safety and explicitly includes all settings of care, including care delivered in the home.

Why does the program emphasize care transitions and cross-setting coordination?

Many medication-related harms occur during transitions (for example, hospital discharge to home or specialist to primary care). Patients and caregivers often manage complex regimens outside clinical environments, so projects are aligned with improving handoffs, reconciliation, education, monitoring, communication, and systems that follow the patient across settings.

Who is encouraged to be involved in funded projects?

AHRQ frames medication safety as a team responsibility and strongly encourages involvement from everyone who touches the medication-use process, including patients and families as active partners. It highlights participation from nurses, pharmacists, pharmacy and medication administration technicians, physicians, health care administrators, and risk managers.

What type of research approach does this opportunity favor?

It favors applied, team-based, real-world research grounded in clinical operations, focused on testing system-level changes and producing evidence on implementation, spread across settings, and sustainability.

Is this funding opportunity still open?

No. The original and current closing date listed is September 25, 2016, and the archive date is October 26, 2016. The announcement is no longer open, but it can still serve as a reference for the types of projects AHRQ has sought.

What are the posted and creation dates for the announcement?

The posted and creation date is November 14, 2013.

Who is eligible to apply?

Eligibility is broad and includes:

  • State governments
  • County governments
  • City or township governments
  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • Federally recognized Native American tribal governments
  • Native American tribal organizations other than federally recognized tribal governments
  • Eligible federal government agencies (as described in the full announcement)

Are non-U.S. (foreign) institutions eligible to apply?

No. The announcement specifies that non-U.S. entities (foreign institutions) are not eligible to apply.

How can applicants find the full announcement text?

The opportunity points readers to the NIH grants guide page for PA-14-002 for the full text.

Who can be contacted for access or linking issues related to the announcement?

The announcement provides NIH Office of Extramural Research (OER) webmaster contact information for access or linking issues.

What is the overall focus of projects AHRQ sought under this opportunity?

Overall, the opportunity supports applied research that makes medication use safer by improving the systems and processes that move medications through care settings and into patients' hands, with a strong emphasis on implementation, cross-setting coordination, and meaningful engagement of both health professionals and patients/families.

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