Opportunity Information: Apply for PAR 11 274

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Advancing the Impact of Effective HIV/AIDS Prevention and Treatment Interventions (R34)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
  • This funding opportunity was created on Jul 26, 2011 and posted on Jul 26, 2011.
  • Applicants must submit their applications by May 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $225,000.00 in funding.
  • Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Special district governments Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) County governments City or township governments Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized) Small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply.
Apply for PAR 11 274

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Opportunity Summary:

This funding opportunity, PAR 11 274, is an NIH grant announcement from the National Institute of Mental Health (NIMH), specifically its Division of AIDS Research (DAR), focused on strengthening the real world impact of HIV/AIDS prevention and treatment interventions that already have evidence behind them. Rather than emphasizing the invention of entirely new interventions, the aim is to support innovative research that helps proven approaches reach more people, work better in everyday settings, and deliver measurable public health benefits. The core problem the FOA is trying to address is the persistent gap between what research has shown can work for HIV prevention and treatment and what is actually used widely and consistently in the communities and systems where it is needed most.

The announcement is positioned as an R34 mechanism, meaning it is intended for developmental, exploratory, or pilot-style projects that can generate the groundwork needed for larger scale effectiveness, implementation, or service delivery studies later on. In practical terms, this kind of award is often used to refine intervention strategies, test feasibility in new settings or populations, adapt delivery methods, build partnerships with real service systems, and develop the data and operational plans needed for a subsequent larger trial or multi-site study. The public health framing is explicit: NIMH is looking for research that can improve uptake, fidelity, sustainability, and reach of effective HIV-related interventions, particularly those relevant to mental health and behavioral factors that influence prevention and treatment outcomes.

The priorities described in the FOA are guided by major federal planning documents, including the National HIV/AIDS Strategy, the NIH Office of AIDS Research (OAR) Plan for HIV/AIDS Related Research, and the NIMH Strategic Plan, especially Objective 4, which emphasizes increasing the public health impact of NIMH-supported science. In that context, the opportunity is fundamentally about translation and impact: evaluating and improving how evidence-based interventions are delivered, collaborating with stakeholders who control or influence service delivery, and building capacity to close the research-to-practice gap. The emphasis on collaboration signals that projects are expected to engage clinics, community organizations, public health departments, schools, corrections, housing programs, or other real-world systems that affect HIV prevention and care.

Administratively, this is a discretionary grant opportunity in the health area under CFDA 93.242 (Mental Health Research Grants). It was posted on July 26, 2011, with an original and final closing date of May 7, 2014, and it was archived on June 7, 2014. The award ceiling listed is $225,000, and there is no cost sharing or matching requirement, which means applicants are not required to provide non-federal funds as a condition of the award.

Eligibility is broad and includes many types of domestic U.S. organizations as well as foreign entities. Eligible applicants include nonprofits (both with and without 501(c)(3) status), public and private institutions of higher education, for-profit organizations other than small businesses, small businesses, and multiple levels of government (state, county, city or township, special district governments), along with independent school districts and housing authorities. The FOA also explicitly includes a wide range of mission-focused institutions and community-serving entities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), tribal governments (including federally recognized and other than federally recognized), faith-based and community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. Importantly, non-U.S. (foreign) institutions may apply, and non-U.S. components of U.S. organizations are also eligible, which opens the door for studies involving international implementation contexts where HIV burden and intervention delivery challenges may be substantial.

For access and technical issues related to the announcement, the listed support contact is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV, and the full announcement was made available through the NIH Grants Guide page associated with PAR 11 274. Overall, the opportunity is best understood as NIH and NIMH investing in the practical science of scaling and strengthening interventions that already work, so that prevention and treatment benefits extend further, last longer, and better reach populations and settings that have historically been underserved or difficult to engage.

Frequently Asked Questions (FAQs) - NIH PAR-11-274 (NIMH/DAR) R34

What is PAR-11-274?

PAR-11-274 is a National Institutes of Health (NIH) funding opportunity announcement from the National Institute of Mental Health (NIMH), specifically NIMH's Division of AIDS Research (DAR). It supports research intended to strengthen the real-world impact of HIV/AIDS prevention and treatment interventions that already have evidence behind them.

What is the main goal of this funding opportunity?

The goal is to close the gap between interventions that research shows are effective for HIV prevention and treatment and what is actually implemented widely and consistently in real communities and service systems. The focus is on improving how proven interventions are delivered so they reach more people, work better in everyday settings, and produce measurable public health benefits.

Is this opportunity meant to invent brand new HIV interventions?

No. The announcement is framed around strengthening, scaling, and improving the delivery of interventions that already have evidence of effectiveness, rather than primarily supporting the invention of entirely new interventions.

What NIH grant mechanism is used in PAR-11-274?

This opportunity uses the R34 mechanism. R34 awards are typically used for developmental, exploratory, or pilot-style projects that lay the groundwork for later, larger effectiveness, implementation, or service delivery studies.

What kinds of activities or projects fit an R34 under this FOA?

Based on the description provided, projects may include refining intervention strategies, testing feasibility in new settings or populations, adapting delivery methods, building partnerships with real service systems, and developing data and operational plans needed for a later larger trial or multi-site study.

What outcomes or improvements is NIMH looking for?

The FOA emphasizes public health impact through improvements such as uptake, fidelity, sustainability, and reach of effective HIV-related interventions, especially those connected to mental health and behavioral factors that influence HIV prevention and treatment outcomes.

What does "real-world impact" mean in the context of this FOA?

In this announcement, real-world impact refers to how well evidence-based HIV interventions perform and persist in everyday practice settings (not just controlled research environments). It includes whether interventions are adopted, implemented consistently, sustained over time, and delivered in ways that produce meaningful population-level benefits.

Are collaborations with service systems and stakeholders expected?

Yes. The FOA highlights collaboration and signals that projects are expected to engage stakeholders and real-world systems that control or influence service delivery, such as clinics, community organizations, public health departments, schools, corrections, housing programs, and other relevant settings.

What federal strategies or plans guide the priorities in this FOA?

The priorities are guided by major federal planning documents, including the National HIV/AIDS Strategy, the NIH Office of AIDS Research (OAR) Plan for HIV/AIDS Related Research, and the NIMH Strategic Plan (especially Objective 4, focused on increasing the public health impact of NIMH-supported science).

What is the CFDA number and program area for this opportunity?

The opportunity is a discretionary grant in the health area under CFDA 93.242, described as Mental Health Research Grants.

What is the maximum award amount listed for PAR-11-274?

The award ceiling listed is $225,000.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement, meaning applicants are not required to provide non-federal funds as a condition of the award.

Who is eligible to apply?

Eligibility is broad. It includes many types of domestic U.S. organizations as well as foreign entities. Eligible applicants include nonprofits (with or without 501(c)(3) status), public and private institutions of higher education, for-profit organizations other than small businesses, small businesses, and various levels of government (state, county, city or township, and special district governments), as well as independent school districts and housing authorities.

Are mission-focused institutions and community-serving organizations eligible?

Yes. The FOA explicitly includes organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), tribal governments (federally recognized and other than federally recognized), faith-based and community-based organizations, regional organizations, and U.S. territories or possessions.

Can foreign (non-U.S.) organizations apply?

Yes. Non-U.S. (foreign) institutions may apply, and non-U.S. components of U.S. organizations are also eligible. This allows for projects that involve international implementation contexts where HIV burden and delivery challenges may be substantial.

Are federal agencies eligible to apply?

Yes. The FOA indicates that eligible federal agencies are included among eligible applicants.

When was this funding opportunity posted and when did it close?

It was posted on July 26, 2011. The original and final closing date was May 7, 2014.

Is this funding opportunity still active?

No. The announcement was archived on June 7, 2014, and the final closing date was May 7, 2014.

Where was the full announcement made available?

The full announcement was made available through the NIH Grants Guide page associated with PAR-11-274.

Who should be contacted for access or technical issues related to the announcement?

For access and technical issues, the listed support contact is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

What problem is this FOA trying to solve?

The FOA targets the persistent gap between what research has shown can work for HIV prevention and treatment and what is actually used widely and consistently in the communities and systems where those interventions are most needed.

How does mental health fit into this HIV-focused opportunity?

The opportunity is housed at NIMH and emphasizes interventions relevant to mental health and behavioral factors that influence HIV prevention and treatment outcomes. The intent is to improve public health impact by improving real-world delivery and performance of effective interventions.

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