Opportunity Information: Apply for PA 13 355

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Advancing the Science of Geriatric Palliative Care (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361 Nursing Research 93.393 Cancer Cause and Prevention Research 93.866 Aging Research.
  • This funding opportunity was created on Jan 2, 2014 and posted on Sep 19, 2013.
  • Applicants must submit their applications by Jan 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments County governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Independent school districts Public housing authorities/Indian housing authorities State governments For profit organizations other than small businesses Public and State controlled institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The National Institutes of Health (NIH) funding opportunity "Advancing the Science of Geriatric Palliative Care (R21)" (Funding Opportunity Number PA 13-355) supports early-stage, exploratory research aimed at improving palliative care for older adults. The central idea is to push the evidence base forward on how to better address symptoms, function, stress, decision-making needs, and overall quality of life for geriatric patients who are living with serious illness or disability. This program is set up under the R21 mechanism, which is typically used to develop and test innovative concepts, generate preliminary data, and explore promising approaches that can later be scaled up through larger studies.

A key feature of this announcement is its strong emphasis on palliative care earlier in the course of illness or disability, rather than care limited to the final days or weeks of life. The FOA specifically notes that hospice and end-of-life settings are not included because NIH has other programs that cover those topics. Instead, the focus is on palliative approaches delivered while patients are still receiving disease-directed treatments or are earlier along a chronic illness trajectory, when supportive care could prevent crises, reduce suffering, and improve patient and caregiver outcomes over time.

The FOA encourages research across a wide range of real-world care settings where older adults commonly receive treatment and support. These settings include ambulatory and outpatient care, hospitals and specific hospital locations such as specialty wards, intensive care units (ICUs), and emergency departments, as well as assisted living facilities and both short-term and long-term care facilities. By naming these settings explicitly, NIH is signaling interest in studies that reflect the clinical environments where geriatric patients and their families actually navigate symptoms, complex care decisions, transitions of care, and the burdens of multimorbidity and functional decline.

In terms of study designs, the announcement is intentionally broad and methodologically inclusive. Applicants may propose observational studies, quasi-experimental designs, or interventional studies, and they may rely on primary data collection, secondary data analyses, or a combination of both. NIH also encourages investigators to leverage existing resources to accelerate progress, such as ongoing cohorts, established intervention studies, research networks, clinical data sources, data and specimen repositories, and other forms of research infrastructure. In practice, this means the FOA welcomes projects that build efficiently on what already exists, for example by embedding palliative care interventions in health systems, using registry or electronic health record data to examine outcomes, or adding palliative-care-relevant measures to active longitudinal studies of aging.

The award information reflects the typical scale of an NIH R21. The listed award ceiling is $200,000, and there is no cost sharing or matching requirement. The opportunity is categorized as discretionary grant funding in the health area, and it is tied to several CFDA numbers that reflect the interdisciplinary nature of the topic, including Nursing Research (93.361), Cancer Cause and Prevention Research (93.393), and Aging Research (93.866). That combination underscores that geriatric palliative care research can span nursing, oncology, geriatrics, health services research, and other related fields.

Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Eligible applicants include public and private institutions of higher education, nonprofits (including 501(c)(3) organizations), for-profit organizations, small businesses, and multiple levels of government such as state, county, city/township, special district governments, and independent school districts, as well as public housing authorities/Indian housing authorities. The FOA also explicitly includes tribal organizations and governments, and it extends eligibility to a wide range of mission-focused institutions and community organizations, including faith-based and community-based organizations, Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), and other minority-serving institutions (including AANAPISIs). Importantly, foreign organizations and foreign institutions are eligible to apply, non-U.S. components of U.S. organizations may participate, and foreign components are allowed under NIH policy, which can enable international comparative work or inclusion of specialized expertise and sites outside the United States when scientifically justified.

As a matter of timing and status, the opportunity was posted on September 19, 2013, created on January 2, 2014, and had a closing date of January 7, 2017, with an archive date of February 7, 2017. That means it is no longer open, but it remains useful as a reference point for NIH priorities and for identifying the kinds of geriatric palliative care research questions and settings NIH has historically sought to support under the R21 exploratory mechanism.

For applicants or researchers trying to locate the full text, NIH listed the opportunity details at http://grants.nih.gov/grants/guide/pa-files/PA-13-355.html (as originally formatted by NIH). NIH also provided support contacts through the NIH Office of Extramural Research (OER) Webmaster for technical access or linking issues at FBOWebmaster@OD.NIH.GOV.

FAQs: Advancing the Science of Geriatric Palliative Care (R21) (PA-13-355)

What is this funding opportunity?

This is a National Institutes of Health (NIH) funding opportunity titled "Advancing the Science of Geriatric Palliative Care (R21)" with Funding Opportunity Number PA 13-355. It supports early-stage, exploratory research to improve palliative care for older adults living with serious illness or disability.

What is the main goal of the program?

The goal is to advance the evidence base for geriatric palliative care, including better ways to address symptoms, function, stress, decision-making needs, and overall quality of life for older adults with serious illness or disability.

What does the R21 mechanism mean for this opportunity?

The R21 mechanism is designed for early-stage and exploratory work. In this FOA, it is positioned to support projects that develop and test innovative concepts, generate preliminary data, and explore promising approaches that could later be expanded through larger studies.

Is this opportunity focused on hospice or end-of-life care?

No. The FOA specifically excludes hospice and end-of-life settings because NIH has other programs that address those topics.

What stage of illness does the FOA emphasize?

The FOA emphasizes palliative care earlier in the course of illness or disability, including when patients are still receiving disease-directed treatments or are earlier in a chronic illness trajectory.

What kinds of patient needs is the FOA trying to address?

It highlights improving support for symptoms, functional issues, stress, complex decision-making, and quality of life for geriatric patients, along with outcomes affecting caregivers over time.

What care settings are specifically named as priorities or examples?

The FOA encourages research in real-world settings where older adults commonly receive care, including ambulatory and outpatient care, hospitals (including specialty wards), intensive care units (ICUs), emergency departments, assisted living facilities, and both short-term and long-term care facilities.

Does the FOA allow studies in hospital-based settings like ICUs and emergency departments?

Yes. The FOA explicitly mentions intensive care units (ICUs) and emergency departments as examples of settings of interest.

Are community-based and residential settings included?

Yes. Assisted living facilities and short-term and long-term care facilities are explicitly included among the settings NIH is interested in.

What types of study designs are allowed?

The FOA is intentionally broad and includes observational studies, quasi-experimental designs, and interventional studies.

Can projects use secondary data instead of collecting new data?

Yes. Applicants may propose primary data collection, secondary data analyses, or a combination of both.

Does NIH encourage using existing research infrastructure?

Yes. The FOA encourages leveraging existing resources such as ongoing cohorts, established intervention studies, research networks, clinical data sources, and data/specimen repositories.

Does the FOA support work embedded in health systems or using clinical data sources like registries or EHRs?

It explicitly encourages leveraging clinical data sources and other infrastructure, which can include registry or electronic health record (EHR) data, as well as embedding approaches within real-world care environments.

What is the maximum award amount listed for this R21?

The listed award ceiling is $200,000.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement.

How is this opportunity categorized?

It is categorized as discretionary grant funding in the health area.

Which CFDA numbers are associated with this opportunity?

The FOA references multiple CFDA numbers reflecting the interdisciplinary scope, including Nursing Research (93.361), Cancer Cause and Prevention Research (93.393), and Aging Research (93.866).

What kinds of organizations are eligible to apply?

Eligibility is broad and includes public and private institutions of higher education, nonprofits (including 501(c)(3) organizations), for-profit organizations, small businesses, and various levels of government (state, county, city/township, special district governments, and independent school districts), as well as public housing authorities/Indian housing authorities.

Are tribal organizations and tribal governments eligible?

Yes. The FOA explicitly includes tribal organizations and tribal governments among eligible applicants.

Are faith-based and community-based organizations eligible?

Yes. The FOA explicitly includes faith-based and community-based organizations.

Are minority-serving institutions eligible to apply?

Yes. The FOA explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), and other minority-serving institutions (including AANAPISIs).

Can non-U.S. organizations apply?

Yes. The FOA states that foreign organizations and foreign institutions are eligible to apply.

Can a U.S. organization include non-U.S. components or foreign components in the project?

Yes. The FOA indicates non-U.S. components of U.S. organizations may participate, and foreign components are allowed under NIH policy when scientifically justified.

Is this funding opportunity still open?

No. The FOA has a closing date of January 7, 2017 and an archive date of February 7, 2017, meaning it is no longer open for applications.

When was this opportunity posted and created?

It was posted on September 19, 2013 and created on January 2, 2014.

Where can someone find the full NIH listing for PA-13-355?

NIH listed the opportunity details at: http://grants.nih.gov/grants/guide/pa-files/PA-13-355.html

Who is the contact for technical access or linking issues?

NIH provided a support contact through the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV for technical access or linking issues.

Why might this archived FOA still be useful?

Even though it is closed, it can still serve as a reference point for NIH priorities and examples of the types of research questions, settings, and methods NIH has historically sought to support for exploratory geriatric palliative care research under the R21 mechanism.

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