Opportunity Information: Apply for RFA AA 15 008

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Alcohol Biosensors (SBIR)(R43/R44)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
  • This funding opportunity was created on Dec 19, 2014 and posted on Dec 19, 2014.
  • Applicants must submit their applications by Apr 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Eligible applicants include: Small businesses.
  • Other Eligible Applicants include the following Only United States small business concerns (SBCs) are eligible to submit applications for this opportunity. A small business concern is one that, at the time of award of Phase I and Phase II, meets all of the following criteria 1. Is organized for profit, with a place of business located in the United States, which operates primarily within the United States or which makes a significant contribution to the United States economy through payment of taxes or use of American products, materials or labor 2. Is in the legal form of an individual proprietorship, partnership, limited liability company, corporation, joint venture, association, trust or cooperative, except that where the form is a joint venture, there must be less than 50 percent participation by foreign business entities in the joint venture 3. i. SBIR and STTR. Be a concern which is more than 50 directly owned and controlled by one or more individuals (who are citizens or permanent resident aliens of the United States), other business concerns (each of which is more than 50 directly owned and controlled by individuals who are citizens or permanent resident aliens of the United States), or any combination of these OR ii. SBIR only. Be a concern which is more than 50 owned by multiple venture capital operating companies, hedge funds, private equity firms, or any combination of these. No single venture capital operating company, hedge fund, or private equity firm may own more than 50 of the concern OR iii. SBIR and STTR. Be a joint venture in which each entity to the joint venture must meet the requirements set forth in paragraph 3 (i) or 3 (ii) of this section. A joint venture that includes one or more concerns that meet the requirements of paragraph (ii) of this section must comply with 121.705(b) concerning registration and proposal requirements. 4. Has, including its affiliates, not more than 500 employees.
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Opportunity Summary:

The Alcohol Biosensors (SBIR) (R43/R44) funding opportunity (RFA-AA-15-008) was a National Institutes of Health grant solicitation aimed at supporting U.S. small businesses that could design and build a wearable biosensor capable of monitoring blood alcohol levels in real time. The central goal was to advance practical, real-world technology for continuous alcohol measurement, with an emphasis on a device that can be worn and provide timely, ongoing readings rather than occasional or retrospective testing. This kind of capability is relevant to alcohol research and could also enable new tools for monitoring, intervention, and data collection in clinical or community settings.

This was a discretionary grant program under the Small Business Innovation Research mechanism, using the NIH SBIR phased award structure: Phase I (R43) for early-stage feasibility and proof-of-concept work, and Phase II (R44) for continued development, refinement, and steps toward commercialization. The announcement specifically targeted small business innovation, meaning applicants were expected to bring an R and D-driven plan that could result in a functional product or prototype and a credible path toward broader use.

Eligibility was limited to U.S. small business concerns as defined under SBIR rules. To qualify, the business needed to be for-profit, have a place of business in the United States, and primarily operate in the U.S. (or otherwise make a significant contribution to the U.S. economy through taxes or use of American labor/materials). Eligible legal structures included common for-profit forms such as LLCs and corporations, as well as partnerships and certain joint ventures, with restrictions on foreign participation in joint ventures. Ownership and control requirements followed SBIR standards, allowing either majority ownership by U.S. citizens or permanent residents (or qualifying U.S.-owned firms), or SBIR-only majority ownership by multiple venture capital operating companies, hedge funds, or private equity firms as long as no single such entity owned more than 50%. The firm (including affiliates) also had to have no more than 500 employees. There was no cost sharing or matching requirement, which generally reduces barriers for smaller companies developing hardware and sensor technologies.

From an administrative standpoint, the opportunity fell under the NIH health funding category and was associated with CFDA 93.273 (Alcohol Research Programs). The estimated total funding amount listed for the opportunity was $2,000,000. The announcement was posted and created on December 19, 2014, with an original and current closing date of April 7, 2015, and it was archived on May 8, 2015. Additional official details were hosted through the NIH Grants Guide at the provided link, and NIH Office of Extramural Research (OER) webmaster contacts were supplied for applicants who had trouble accessing or linking to the full announcement.

Frequently Asked Questions (FAQs)

What is the Alcohol Biosensors (SBIR) (R43/R44) funding opportunity?

This opportunity (RFA-AA-15-008) was a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) grant solicitation focused on supporting U.S. small businesses developing alcohol biosensor technology.

What was the main purpose of this funding opportunity?

The central goal was to help small businesses design and build a wearable biosensor capable of monitoring blood alcohol levels in real time, emphasizing practical, real-world use and continuous measurement rather than occasional or retrospective testing.

What kind of technology was NIH trying to advance through this solicitation?

The solicitation emphasized wearable technology that can be worn comfortably and provide timely, ongoing blood alcohol readings in real time, supporting continuous alcohol measurement for research and potential applied monitoring uses.

Why was real-time, continuous alcohol monitoring emphasized?

Continuous, real-time measurement can provide timely and ongoing readings, which can be especially useful for alcohol research and for enabling new tools for monitoring, intervention, and data collection in clinical or community settings.

Which grant mechanism was used for this opportunity?

This was a discretionary grant program under the NIH Small Business Innovation Research (SBIR) mechanism using the NIH SBIR phased award structure: Phase I (R43) and Phase II (R44).

What is Phase I (R43) intended to support?

Phase I (R43) was intended to support early-stage feasibility and proof-of-concept work.

What is Phase II (R44) intended to support?

Phase II (R44) was intended to support continued development and refinement, along with steps toward commercialization.

Was this opportunity specifically aimed at small business innovation?

Yes. The announcement specifically targeted small business innovation, meaning applicants were expected to propose an R&D-driven plan that could result in a functional product or prototype and include a credible path toward broader use.

Who was eligible to apply?

Eligibility was limited to U.S. small business concerns as defined under SBIR rules.

What basic business characteristics were required for eligibility?

To qualify, the business had to be for-profit, have a place of business in the United States, and primarily operate in the U.S., or otherwise make a significant contribution to the U.S. economy through taxes or use of American labor and materials.

What legal business structures could be eligible?

Eligible legal structures included common for-profit forms such as LLCs and corporations, as well as partnerships and certain joint ventures (with restrictions on foreign participation in joint ventures).

Were there ownership and control requirements?

Yes. Ownership and control requirements followed SBIR standards, including majority ownership by U.S. citizens or permanent residents (or qualifying U.S.-owned firms), or SBIR-only majority ownership by multiple venture capital operating companies, hedge funds, or private equity firms as long as no single such entity owned more than 50%.

Was there an employee size limit for applicants?

Yes. The firm, including affiliates, had to have no more than 500 employees.

Did the opportunity require cost sharing or matching funds?

No. There was no cost sharing or matching requirement stated for this opportunity.

What NIH or federal program category did this fall under?

The opportunity fell under the NIH health funding category and was associated with CFDA 93.273 (Alcohol Research Programs).

How much total funding was estimated for this opportunity?

The estimated total funding amount listed for the opportunity was $2,000,000.

What was the posting date for the announcement?

The announcement was posted and created on December 19, 2014.

What was the application closing date?

The original and current closing date listed was April 7, 2015.

Is this opportunity still open?

No. It was archived on May 8, 2015, and the closing date listed was April 7, 2015.

Where could applicants find the official funding announcement details?

Additional official details were hosted through the NIH Grants Guide (via the link provided in the opportunity listing).

Who could applicants contact if they had trouble accessing the official announcement?

The opportunity listing indicated that NIH Office of Extramural Research (OER) webmaster contacts were supplied for applicants who had trouble accessing or linking to the full announcement.

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