Opportunity Information: Apply for PA 10 100
Apply for PA 10 100
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Alcohol Use Disorders Treatment, Services Research, and Recovery (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
- This funding opportunity was created on Mar 28, 2013 and posted on Mar 17, 2010.
- Applicants must submit their applications by Mar 29, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) State governments Private institutions of higher education For profit organizations other than small businesses Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Alcohol Use Disorders Treatment, Services Research, and Recovery (R01) opportunity (Funding Opportunity Number PA-10-100) is a discretionary NIH grant program administered by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Its central aim is to fund research that improves how alcohol use disorders (AUD) are treated and how recovery is supported in real-world settings. The announcement emphasizes three broad, interconnected areas: (1) behavioral and pharmacological treatments for AUD, (2) services research focused on the organizational, financial, and management conditions that either help or hinder service delivery, and (3) research on the process and outcomes of recovery from AUD. In practice, this means the program is not limited to testing whether a treatment works in a controlled environment; it also encourages studies that examine how treatment and recovery supports can be implemented, financed, managed, sustained, and made accessible across different systems of care.
The funding mechanism is the NIH Research Project Grant (R01), which is typically used for mature, hypothesis-driven projects that require a substantial scope of work, multi-year effort, and a well-developed research plan. This FOA is part of a set of three parallel announcements with the same scientific scope but different grant mechanisms: an R21 option (PA-10-102) for exploratory or early-stage projects, and an R03 option (PA-10-101) for smaller, more limited studies. Applicants who have a more developed program of research, larger sample needs, or more complex designs would generally align with the R01 pathway, while those proposing pilot work or narrower questions might consider the companion FOAs.
Because proposed projects can vary widely in design and complexity, the FOA does not set a single award size or fixed number of awards. Instead, the total dollars awarded and the number of funded projects depend on the mix of applications received, their scientific merit, their proposed duration, and the requested budgets. Cost sharing or matching is not required, which is typical for NIH research grants and reduces barriers for applicants that may not have non-federal resources to contribute.
Eligibility is intentionally broad. Beyond standard academic and nonprofit research institutions, the FOA allows applications from state governments, public and private institutions of higher education, for-profit organizations (including small businesses), non-501(c)(3) nonprofits, and tribal entities (including federally recognized tribal governments). It also explicitly includes a wide range of mission-driven and capacity-building institution types and community organizations, such as faith-based or community-based organizations, Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), U.S. territories or possessions, eligible federal agencies, and even non-U.S. (foreign) organizations and regional organizations. That breadth signals an interest in supporting research that can be grounded in diverse care settings and populations, including groups that are often underrepresented in clinical research and services research.
Administratively, the opportunity was posted March 17, 2010, with later record dates reflecting updates and archiving, and it is associated with CFDA 93.273 (Alcohol Research Programs). The full announcement was made available through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PA-10-100.html. For technical issues accessing or linking to the notice, the contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@od.nih.gov.
Overall, PA-10-100 is best understood as an NIH R01 pathway for rigorous research that can move the AUD field forward not only by improving interventions (behavioral and medication-based), but also by tackling practical barriers and facilitators in treatment systems and by deepening understanding of recovery as a real-world, often long-term process shaped by services, supports, organizations, and communities.
Frequently Asked Questions (FAQs)
What is the Alcohol Use Disorders Treatment, Services Research, and Recovery (R01) opportunity?
This opportunity is an NIH discretionary research grant program focused on alcohol use disorders (AUD). It supports research designed to improve how AUD treatment is delivered and how recovery is supported in real-world settings. The Funding Opportunity Number is PA-10-100, and it is administered by the National Institute on Alcohol Abuse and Alcoholism (NIAAA).
What is the main goal of PA-10-100?
The central aim is to fund research that improves the treatment of alcohol use disorders and strengthens recovery support, especially in real-world environments where care is actually delivered. The program encourages studies that go beyond controlled efficacy testing and address implementation, accessibility, financing, management, sustainment, and system-level barriers and facilitators.
Which NIH institute administers this funding opportunity?
The program is administered by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), a component of the National Institutes of Health (NIH).
What grant mechanism does this opportunity use?
PA-10-100 uses the NIH Research Project Grant mechanism (R01), which is commonly used for mature, hypothesis-driven research projects that require a substantial scope of work, multi-year effort, and a well-developed research plan.
What kinds of research topics does the FOA emphasize?
The announcement highlights three broad, interconnected areas: (1) behavioral and pharmacological treatments for AUD, (2) services research on organizational, financial, and management conditions that help or hinder service delivery, and (3) research on the process and outcomes of recovery from AUD.
Does the program only support studies of treatment effectiveness in controlled settings?
No. While intervention research is included, the announcement explicitly encourages research that also examines real-world conditions, such as how treatment and recovery supports can be implemented, financed, managed, sustained, and made accessible across different systems of care.
How is this R01 opportunity related to other funding announcements?
PA-10-100 is part of a set of three parallel announcements that share the same scientific scope but use different NIH grant mechanisms. The companion options listed are an R21 (PA-10-102) for exploratory or early-stage projects and an R03 (PA-10-101) for smaller, more limited studies.
When would an applicant typically choose the R01 pathway instead of the R21 or R03 options?
Based on the description, applicants with a more developed program of research, larger sample needs, or more complex designs would generally align with the R01 mechanism, while those proposing pilot work or narrower questions might consider the companion R21 or R03 announcements.
Is there a fixed award size or a set number of awards for PA-10-100?
No. The FOA does not specify a single award size or a fixed number of awards. The number of funded projects and total dollars awarded depend on factors such as the mix of applications received, scientific merit, proposed duration, and requested budgets.
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching, which is consistent with typical NIH research grant practices.
Who is eligible to apply?
Eligibility is broad. The FOA allows applications from a wide range of organizations, including state governments; public and private institutions of higher education; for-profit organizations (including small businesses); non-501(c)(3) nonprofits; and tribal entities, including federally recognized tribal governments.
Does the FOA include community-based or faith-based organizations as eligible applicants?
Yes. The eligibility language explicitly includes faith-based or community-based organizations among the organizations that may apply.
Are minority-serving and capacity-building institutions eligible?
Yes. The FOA explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities (TCCUs), among other institution types.
Are U.S. territories or possessions included in eligible applicants?
Yes. U.S. territories or possessions are explicitly included among eligible applicant types.
Can federal agencies apply?
Yes. The FOA lists eligible federal agencies among eligible applicants.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. The FOA explicitly states that non-U.S. (foreign) organizations and regional organizations are eligible.
What CFDA number is associated with this opportunity?
This opportunity is associated with CFDA 93.273 (Alcohol Research Programs).
When was this opportunity posted?
The opportunity was posted on March 17, 2010. The description also notes later record dates reflecting updates and archiving.
Where can applicants find the full funding announcement?
The full announcement is available through the NIH grants guide at: http://grants.nih.gov/grants/guide/pa-files/PA-10-100.html
Who should be contacted for technical issues accessing or linking to the notice?
For technical issues accessing or linking to the notice, the listed contact is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@od.nih.gov.
What does this program signal about the types of settings and populations it aims to support?
The broad eligibility and the focus on real-world services and recovery supports signal interest in research grounded in diverse care settings and populations, including groups often underrepresented in clinical research and services research.
In plain terms, what does PA-10-100 aim to move forward in the AUD field?
It aims to advance AUD research by improving interventions (behavioral and medication-based), addressing practical barriers and facilitators in treatment systems, and deepening understanding of recovery as a real-world, often long-term process shaped by services, supports, organizations, and communities.
Browse more opportunities from the same category: Health
Next opportunity: Alcohol Use Disorders Treatment, Services Research, and Recovery (R21)
Previous opportunity: Stress Pathways in Alcohol Induced Organ Injury and Protection (R01)
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