Opportunity Information: Apply for RFA AG 16 018
Apply for RFA AG 16 018
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Alzheimers Disease Core Centers (P30)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Aug 12, 2015 and posted on Aug 7, 2015.
- Applicants must submit their applications by Oct 28, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $16,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $900,000.00 in funding.
- The number of recipients for this funding is limited to 10 candidate(s).
- Eligible applicants include: City or township governments Special district governments Public and State controlled institutions of higher education State governments Independent school districts Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses County governments Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Small businesses Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply.Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The National Institutes of Health (NIH) funding opportunity RFA-AG-16-018, titled "Alzheimers Disease Core Centers (P30)," supports the establishment and ongoing operation of Alzheimers Disease Core Centers (ADCCs). These centers are meant to function as institution-based hubs that both conduct research and provide shared infrastructure for a broad community of investigators focused on Alzheimers disease (AD) and related disorders. A central aim is to strengthen and accelerate high-quality AD research by offering common resources, organized expertise, and coordinated services that individual labs typically cannot sustain on their own.
A key focus of the ADCC model is the distinction between disease processes and conditions that can look similar clinically. The announcement emphasizes work that helps differentiate Alzheimers disease and related neurodegenerative disorders from normal brain aging and from mild cognitive impairment (MCI). In practice, that means ADCCs are expected to support research programs that can sharpen diagnostic boundaries, improve clinical and biological characterization of patients, and refine understanding of early and preclinical stages of disease. The centers are also framed as engines for translation, meaning the infrastructure should help move discoveries toward improved diagnostic approaches, prevention strategies, and treatments, rather than stopping at basic observations.
The FOA describes these centers as shared research resources, which implies a strong emphasis on core facilities, services, and coordinated capabilities that can be used by multiple investigators. While the source text does not list the specific cores, the intent is clear: provide a stable platform that makes research more efficient, standardized, and collaborative. Alongside direct research support, ADCCs are expected to contribute to training by creating an environment where researchers can build skills, access specialized methods, and learn emerging approaches in the AD field. The FOA also highlights developing novel techniques and methodologies, positioning the centers as places where new tools, measures, and research approaches can be created, tested, and disseminated for broader use.
This opportunity is a discretionary grant using the NIH P30 mechanism, which is commonly used for center core grants that support shared infrastructure rather than a single, narrowly defined research project. The activity category is health, and the CFDA number listed is 93.866 (Aging Research). NIH anticipated making about 10 awards under this announcement, with an estimated total funding amount of $16,000,000. The listed award ceiling is $900,000, and there is no cost sharing or matching requirement, meaning applicants are not required to commit non-federal funds as a condition of eligibility.
Eligibility is broad and includes many types of U.S.-based organizations and governmental entities. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including those with and without 501(c)(3) status), for-profit organizations other than small businesses, small businesses, and a range of government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The FOA also explicitly includes a number of mission- or community-focused institution types and organizations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and U.S. territories or possessions. Foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible to apply; however, foreign components as defined under the NIH Grants Policy Statement are allowed, which typically means a U.S. applicant may include certain clearly justified international elements within an otherwise domestic application.
Key dates included a posted date of August 7, 2015, with an original closing date of October 6, 2015, and a current closing date of October 28, 2015. The opportunity was archived on November 28, 2015. For applicants or interested parties seeking the full announcement details, the FOA points to the NIH grants guide page at http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-16-018.html. For technical issues accessing or linking to the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: NIH RFA-AG-16-018 - Alzheimers Disease Core Centers (P30)
What is the funding opportunity called?
The opportunity is NIH RFA-AG-16-018, titled "Alzheimers Disease Core Centers (P30)."
What is the purpose of this funding opportunity?
This funding opportunity supports the establishment and ongoing operation of Alzheimers Disease Core Centers (ADCCs). The centers are intended to serve as institution-based hubs that conduct research and provide shared infrastructure for a broad community of investigators working on Alzheimers disease (AD) and related disorders.
What is an Alzheimers Disease Core Center (ADCC) in this program?
An ADCC is described as a shared research resource and an institutional hub. It is expected to both support research directly and provide common resources, organized expertise, and coordinated services that individual labs typically cannot sustain on their own.
What kind of research emphasis does the FOA highlight?
The FOA emphasizes work that helps distinguish Alzheimers disease and related neurodegenerative disorders from normal brain aging and from mild cognitive impairment (MCI). The centers are expected to support research that sharpens diagnostic boundaries, improves clinical and biological characterization of patients, and refines understanding of early and preclinical stages of disease.
Does the FOA emphasize translation to clinical impact?
Yes. The centers are framed as engines for translation, meaning the infrastructure should help move discoveries toward improved diagnostic approaches, prevention strategies, and treatments, rather than stopping at basic observations.
What does it mean that ADCCs are "shared research resources"?
It means the model places strong emphasis on core facilities, services, and coordinated capabilities that can be used by multiple investigators. The intent is to provide a stable platform that makes research more efficient, standardized, and collaborative.
Are specific cores or facilities listed in the provided information?
No. The provided information does not list specific cores, but it clearly indicates that shared infrastructure, coordinated services, and common resources are central to the ADCC model.
Does the program include a training component?
Yes. ADCCs are expected to contribute to training by creating an environment where researchers can build skills, access specialized methods, and learn emerging approaches in the Alzheimers disease field.
Does the FOA encourage development of new methods or tools?
Yes. The FOA highlights developing novel techniques and methodologies, positioning the centers as places where new tools, measures, and research approaches can be created, tested, and disseminated for broader use.
What NIH grant mechanism is used?
This is a discretionary grant using the NIH P30 mechanism, which is commonly used for center core grants that support shared infrastructure rather than a single, narrowly defined research project.
What is the activity category and CFDA number?
The activity category is health. The CFDA number listed is 93.866 (Aging Research).
How many awards did NIH anticipate making?
NIH anticipated making about 10 awards under this announcement.
What was the estimated total funding amount?
The estimated total funding amount listed is $16,000,000.
What is the award ceiling?
The listed award ceiling is $900,000.
Is cost sharing or matching required?
No. There is no cost sharing or matching requirement, meaning applicants are not required to commit non-federal funds as a condition of eligibility.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S.-based organizations and governmental entities. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including those with and without 501(c)(3) status), for-profit organizations other than small businesses, small businesses, and government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Are minority-serving or community-focused institutions included in eligibility?
Yes. The FOA explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations.
Are U.S. territories eligible?
Yes. U.S. territories or possessions are included as eligible applicants in the provided information.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible to apply.
Are non-U.S. components of U.S. organizations eligible to apply?
No. Non-U.S. components of U.S. organizations are not eligible to apply.
Are any international elements allowed within an application?
Yes. Foreign components (as defined under the NIH Grants Policy Statement) are allowed. This typically means a U.S. applicant may include certain clearly justified international elements within an otherwise domestic application.
When was the opportunity posted?
The posted date is August 7, 2015.
What were the closing dates listed for this opportunity?
The original closing date was October 6, 2015, and the current closing date listed was October 28, 2015.
Is this funding opportunity still active?
No. The opportunity was archived on November 28, 2015.
Where can someone find the full FOA details?
The FOA points to the NIH grants guide page at http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-16-018.html.
Who should be contacted for technical issues accessing or linking to the announcement?
For technical issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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