Opportunity Information: Apply for RFA AG 11 005
Apply for RFA AG 11 005
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Alzheimers Disease Core Centers (P30)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Jul 15, 2010 and posted on Jul 15, 2010.
- Applicants must submit their applications by Oct 13, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $14,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) .
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Opportunity Summary:
The Alzheimers Disease Core Centers (P30) funding opportunity (RFA-AG-11-005) is a National Institute on Aging (NIA), NIH grant program meant to support institution-based research centers focused on Alzheimers disease and closely related conditions. The central idea is to build or sustain a shared, coordinated core infrastructure that multiple investigators can use, rather than funding only individual, stand-alone projects. These centers are expected to strengthen and accelerate Alzheimers research by providing centralized resources, services, expertise, and collaboration space that make studies more efficient, more comparable across labs, and more likely to translate into practical clinical advances.
A major emphasis of the program is helping the field better understand and separate Alzheimers disease and related disorders from normal brain aging and mild cognitive impairment (MCI). In practice, that means supporting research and shared capabilities that can clarify what is disease-related versus what might be expected as part of typical aging, and that can refine the ability to characterize and track early or transitional stages such as MCI. The centers are also intended to serve as platforms where new techniques and methodologies can be developed, tested, and disseminated, which can include improvements in clinical assessment approaches, biomarker strategies, data collection methods, neuropathology procedures, imaging workflows, or other tools that improve rigor and reproducibility in Alzheimers research.
The opportunity also explicitly highlights training and translation. Training refers to building an environment where developing researchers can gain access to specialized resources and multidisciplinary mentorship, supported by the center structure. Translation refers to moving research findings toward better real-world outcomes, particularly improved strategies for diagnosis, prevention, and treatment. The expectation is that by concentrating expertise and shared resources within a core center model, research can more quickly generate findings that inform clinical practice or guide the next generation of therapeutic and preventive approaches.
This announcement uses the NIH P30 mechanism, which is commonly used for center core grants. Under a P30, funds generally support shared cores and centralized activities that enable and enhance research across a group of investigators, rather than serving as a single-project research grant. The NIA planned, for fiscal year 2011, to commit approximately 14,000,000 in total costs to support an anticipated 8 to 10 awards, covering new and/or competing continuation grants. The funding instrument type is a grant, and the activity category is health, listed under CFDA 93.866 (Aging Research). There is no cost sharing or matching requirement stated for this opportunity.
Eligibility is aimed broadly at qualified institutions, including public and state-controlled institutions of higher education and private institutions of higher education, along with other eligible applicants as specified in the announcement. The listed additional eligible applicant categories include Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs), reflecting an openness to a range of institutional types that can host a robust center infrastructure and contribute meaningfully to the Alzheimers research enterprise.
Key administrative details include a posted date of July 15, 2010, an original and current closing date of October 13, 2010, and an archive date of November 13, 2010. The full announcement was made available through the NIH Grants Guide at the provided link (http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-11-005.html). For technical access issues, the contact point listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: Alzheimer's Disease Core Centers (P30) - RFA-AG-11-005
What is the Alzheimer's Disease Core Centers (P30) funding opportunity?
This opportunity (RFA-AG-11-005) is a National Institute on Aging (NIA), NIH program that funds institution-based research centers focused on Alzheimer's disease and closely related conditions using the NIH P30 (center core grant) mechanism.
What is the main purpose of this program?
The central purpose is to build or sustain a shared, coordinated core infrastructure that multiple investigators can use. Instead of supporting only individual, stand-alone projects, the program supports centralized resources, services, expertise, and collaboration space that can strengthen and accelerate Alzheimer's research.
What does "P30 mechanism" mean in the context of this opportunity?
The NIH P30 mechanism is commonly used for center core grants. In this program, funds generally support shared cores and centralized activities that enable and enhance research across a group of investigators, rather than operating as a single-project research grant.
What kinds of research areas are these centers expected to focus on?
The centers are expected to focus on Alzheimer's disease and closely related conditions, with an emphasis on improving how the field understands, distinguishes, and characterizes Alzheimer's disease and related disorders.
How does the program address the difference between Alzheimer's disease and normal brain aging?
A major emphasis is improving understanding of what is disease-related versus what may be expected as part of typical aging. The program supports research and shared capabilities that help clarify and separate Alzheimer's disease and related disorders from normal brain aging.
Does the program specifically mention mild cognitive impairment (MCI)?
Yes. The opportunity highlights the importance of refining the ability to characterize and track early or transitional stages such as mild cognitive impairment (MCI), including distinguishing MCI and related disorders from normal aging and Alzheimer's disease.
What role do shared cores and infrastructure play in these centers?
Shared cores and coordinated infrastructure are intended to make studies more efficient, more comparable across labs, and more likely to translate into practical clinical advances by centralizing resources, services, and expertise for multiple investigators.
What types of resources or capabilities might a center develop or provide?
The announcement describes centers as platforms for developing, testing, and disseminating new techniques and methodologies. Examples mentioned include improvements in clinical assessment approaches, biomarker strategies, data collection methods, neuropathology procedures, imaging workflows, and other tools that improve rigor and reproducibility in Alzheimer's research.
Is training part of the expected center activities?
Yes. The opportunity explicitly highlights training, described as building an environment where developing researchers can gain access to specialized resources and multidisciplinary mentorship supported by the center structure.
What does "translation" mean in this funding opportunity?
Translation refers to moving research findings toward better real-world outcomes, particularly improved strategies for diagnosis, prevention, and treatment. The expectation is that concentrating expertise and shared resources in a core center model can help research generate findings that inform clinical practice or guide future therapeutic and preventive approaches.
Who is the sponsoring institute for this opportunity?
The program is sponsored by the National Institute on Aging (NIA), part of the National Institutes of Health (NIH).
What is the funding instrument type and activity category?
The funding instrument type is a grant. The activity category is health.
What CFDA number is associated with this opportunity?
The opportunity is listed under CFDA 93.866 (Aging Research).
How much funding was NIA planning to commit, and how many awards were anticipated?
For fiscal year 2011, NIA planned to commit approximately $14,000,000 in total costs to support an anticipated 8 to 10 awards, covering new and/or competing continuation grants.
Are cost sharing or matching funds required?
No cost sharing or matching requirement is stated for this opportunity.
What types of institutions are eligible to apply?
Eligibility is aimed broadly at qualified institutions, including public and state-controlled institutions of higher education and private institutions of higher education, along with other eligible applicants as specified in the announcement.
Are minority-serving or tribally controlled institutions included in the eligible applicant categories?
Yes. The announcement lists additional eligible applicant categories including Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
What is the posted date for this funding opportunity?
The posted date is July 15, 2010.
What is the application closing date?
The original and current closing date is October 13, 2010.
What is the archive date for this announcement?
The archive date is November 13, 2010.
Where can applicants find the full announcement text?
The full announcement is available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-11-005.html
Who should be contacted for technical access issues related to the announcement?
For technical access issues, the listed contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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