Opportunity Information: Apply for RFA AG 13 019
Apply for RFA AG 13 019
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Alzheimers Disease Research Centers (P50)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Apr 15, 2013 and posted on Mar 1, 2013.
- Applicants must submit their applications by Jun 11, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $10,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities City or township governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Public and State controlled institutions of higher education State governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Small businesses Independent school districts Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Alzheimers Disease Research Centers (P50) funding opportunity (RFA-AG-13-019) is a National Institutes of Health (NIH) grant program administered by the National Institute on Aging (NIA) to support institution-based centers focused on Alzheimers disease (AD) and closely related disorders. The core idea is to fund comprehensive research centers that do more than run isolated projects. ADRCs are expected to function as shared, collaborative hubs that bring together expertise, participants, data, and specialized infrastructure to accelerate progress across the AD research pipeline, from basic discovery to clinical translation and, ultimately, improved patient care.
A central purpose of the program is to strengthen and coordinate research that improves understanding of AD while also clarifying how AD differs from normal brain aging and from mild cognitive impairment (MCI). Because distinguishing these processes is essential for accurate diagnosis and appropriate intervention, ADRCs are positioned to contribute to better characterization of disease trajectories, biomarkers, and clinical phenotypes. The centers are meant to serve as shared research resources that other investigators can leverage, helping to standardize approaches, enable multi-investigator and multidisciplinary work, and increase the pace and quality of discoveries in AD and related dementias.
Beyond conducting research, ADRCs are also expected to provide a platform for training and workforce development in the AD field. This includes creating an environment where clinicians and scientists can learn advanced methods, work with specialized datasets, and participate in collaborative center activities that expose them to clinical research operations, participant recruitment and characterization, and translational study design. The program also emphasizes the development of novel techniques and methodologies, reflecting an expectation that centers will contribute not only new findings but also improved tools and approaches that can be broadly adopted by the field.
Another major component described in the opportunity is the collection of biospecimens useful for clinical research. ADRCs commonly serve as structured points of access for well-characterized participant samples and associated clinical information, which can support biomarker discovery, validation studies, and investigations linking biology to clinical outcomes. By building and maintaining these resources within a coordinated center framework, the program aims to reduce barriers that slow progress, such as limited access to high-quality specimens, inconsistent phenotyping, or insufficient infrastructure for complex clinical studies.
The translation of research findings into practical outcomes is a defining feature of the ADRC model. The announcement frames translation broadly, including improvements in diagnostics, prevention strategies, treatments, and care approaches. In other words, the expectation is that centers will help move the field toward earlier and more accurate detection, better risk reduction and prevention concepts, more effective therapeutic development and testing, and evidence-based strategies to improve quality of life for people living with AD and for caregivers.
From an administrative standpoint, this is a discretionary grant opportunity using the NIH P50 center grant mechanism. The opportunity was posted March 1, 2013, with an original and final application due date of June 11, 2013, and an archive date of July 12, 2013. The estimated total funding amount listed is $10,000,000, and the CFDA number associated with the program is 93.866 (Aging Research). There is no cost sharing or matching requirement indicated, meaning applicants are not required to provide matching funds as a condition of award.
Eligibility is broad across U.S.-based organizations and government entities, including public and state-controlled and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations (including small businesses), and various levels of government (state, county, city/township, special district). The eligibility language also explicitly includes a range of mission-focused institutions and community-serving entities such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions, as well as faith-based and community-based organizations and regional organizations. Foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible; however, foreign components as defined under NIH policy are allowed, which typically means a U.S. applicant may include certain foreign elements when justified and permitted under NIH rules.
For reference and full requirements, the announcement points applicants to the NIH funding opportunity page at http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-13-019.html, and provides NIH Office of Extramural Research (OER) webmaster contacts for access or technical linking issues.
Frequently Asked Questions (FAQs)
What is the Alzheimers Disease Research Centers (P50) funding opportunity (RFA-AG-13-019)?
It is an NIH discretionary grant opportunity administered by the National Institute on Aging (NIA) to support institution-based Alzheimers Disease Research Centers (ADRCs). The program uses the NIH P50 center grant mechanism to fund comprehensive, collaborative research centers focused on Alzheimer's disease (AD) and closely related disorders.
Which NIH Institute administers this program?
The program is administered by the National Institute on Aging (NIA), which is part of the National Institutes of Health (NIH).
What is the main goal of the ADRC program?
The central goal is to fund comprehensive research centers that operate as shared, collaborative hubs, rather than isolated projects. ADRCs are expected to bring together expertise, participants, data, and specialized infrastructure to speed progress across the AD research pipeline, from basic discovery through clinical translation and toward improved patient care.
How are ADRCs expected to operate compared with single-project grants?
ADRCs are intended to function as coordinated, institution-based centers that support multi-investigator and multidisciplinary work. They are described as shared research resources that other investigators can leverage, helping standardize approaches, enable collaboration, and increase the pace and quality of discoveries in AD and related dementias.
What disease areas does this opportunity focus on?
The focus is on Alzheimer's disease (AD) and closely related disorders, including research that helps clarify how AD differs from normal brain aging and from mild cognitive impairment (MCI).
Why does the announcement emphasize distinguishing AD from normal aging and MCI?
The announcement highlights that distinguishing these processes is essential for accurate diagnosis and appropriate intervention. ADRCs are positioned to improve characterization of disease trajectories, biomarkers, and clinical phenotypes to help clarify these differences.
Does this program support clinical translation, or only basic research?
The ADRC model explicitly spans the full pipeline, from basic discovery to clinical translation and ultimately improved patient care. Translation is framed broadly and includes diagnostics, prevention strategies, treatments, and care approaches.
What kinds of practical outcomes are ADRCs expected to support?
The announcement describes translation to include earlier and more accurate detection, better risk reduction and prevention concepts, more effective therapeutic development and testing, and evidence-based strategies to improve quality of life for people living with AD and for caregivers.
Are ADRCs expected to serve as shared resources for other researchers?
Yes. The centers are meant to serve as shared research resources that other investigators can use, supporting standardized approaches and enabling multi-investigator, multidisciplinary research.
Is training or workforce development part of the ADRC expectations?
Yes. ADRCs are expected to provide a platform for training and workforce development in the AD field, including an environment where clinicians and scientists can learn advanced methods, work with specialized datasets, and participate in collaborative center activities.
What kinds of training experiences are mentioned?
The announcement points to exposure to clinical research operations, participant recruitment and characterization, and translational study design, along with opportunities to work with specialized datasets and advanced methods within the center environment.
Does the opportunity emphasize development of new methods or tools?
Yes. The program emphasizes developing novel techniques and methodologies, with an expectation that centers will contribute improved tools and approaches that can be broadly adopted by the field.
Are biospecimens part of the ADRC model described in this opportunity?
Yes. A major component described is the collection of biospecimens useful for clinical research. ADRCs commonly serve as structured points of access for well-characterized participant samples and associated clinical information.
How are biospecimens and associated data expected to be used?
The resources can support biomarker discovery, validation studies, and investigations linking biology to clinical outcomes. The coordinated center framework is described as a way to reduce barriers such as limited access to high-quality specimens, inconsistent phenotyping, or insufficient infrastructure for complex clinical studies.
What grant mechanism is used for this funding opportunity?
This opportunity uses the NIH P50 center grant mechanism.
Is this a discretionary grant?
Yes. The announcement describes it as a discretionary grant opportunity.
What are the key dates for this opportunity?
The opportunity was posted on March 1, 2013. The original and final application due date was June 11, 2013. The archive date was July 12, 2013.
How much total funding is estimated for this opportunity?
The estimated total funding amount listed is $10,000,000.
What is the CFDA number associated with this program?
The CFDA number is 93.866, labeled as Aging Research.
Is cost sharing or matching required?
No. The information provided indicates there is no cost sharing or matching requirement, meaning applicants are not required to provide matching funds as a condition of award.
Who is eligible to apply?
Eligibility is broad across U.S.-based organizations and government entities. This includes public and state-controlled and private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status); for-profit organizations (including small businesses); and various levels of government (state, county, city/township, special district).
Are specific institution types explicitly included in the eligibility language?
Yes. The eligibility language explicitly includes HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions, faith-based and community-based organizations, and regional organizations.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible to apply.
Are non-U.S. components of U.S. organizations eligible?
No. Non-U.S. components of U.S. organizations are not eligible according to the information provided.
Are any foreign-related activities allowed under this opportunity?
Yes, foreign components (as defined under NIH policy) are allowed. This typically means a U.S. applicant may include certain foreign elements when justified and permitted under NIH rules.
Where can applicants find the full funding announcement and requirements?
The announcement points to the NIH funding opportunity page at: http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-13-019.html
Who is listed for help with access or technical linking issues?
The opportunity references NIH Office of Extramural Research (OER) webmaster contacts for access or technical linking issues.
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