Opportunity Information: Apply for PA 16 029
Apply for PA 16 029
- The HHS-NIH11 in the education, health sector is offering a public funding opportunity titled "Applying Metabolomics to Drive Biomarker Discovery in Symptom Science (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213, 93.361,.
- This funding opportunity was created on Nov 03, 2015 and posted on Nov 03, 2015.
- Applicants must submit their applications by Jan 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
Applying Metabolomics to Drive Biomarker Discovery in Symptom Science (R21) (Funding Opportunity Number PA-16-029) is a discretionary grant opportunity from the U.S. Department of Health and Human Services, National Institutes of Health (listed as HHS-NIH11). The focus is on using metabolomics, meaning large-scale measurement and analysis of small molecules and metabolic products in biological samples, as a tool for discovering biomarkers that can improve symptom science. In practical terms, the program is looking for research that can identify measurable biological signatures linked to symptoms, with the end goal of improving how symptoms are understood, assessed, and managed in health and clinical care contexts.
This opportunity uses the NIH R21 mechanism, which is typically designed to support exploratory or early-stage projects that may be higher risk but have the potential to open up new directions. Here, that exploratory emphasis aligns with metabolomics-driven biomarker discovery, where projects often involve testing novel analytical pipelines, identifying candidate metabolite patterns, or generating preliminary evidence that a metabolic signature tracks with a symptom or symptom cluster. The funding activity category is listed under Education and Health, and the associated CFDA numbers are 93.213 and 93.361, reflecting NIH program areas tied to this announcement.
The announcement is broadly open in terms of who can apply. Eligible applicants include multiple levels of government (state, county, city/township, and special district governments), independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, other Native American tribal organizations, public housing authorities/Indian housing authorities, nonprofits both with and without 501(c)(3) status (excluding higher education institutions in those specific nonprofit categories), for-profit organizations other than small businesses, small businesses, and additional applicant types as described in the full eligibility text. This wide eligibility is meant to encourage participation from universities, medical and research centers, community-based organizations, tribal entities, and industry groups that have the technical capacity to conduct metabolomics and biomarker research.
Key administrative details included in the source data are that the opportunity was created and posted on November 3, 2015, with an original and current closing date of January 7, 2019. The award ceiling is listed as $200,000, indicating a maximum funding limit under this announcement (as presented in the provided data). The number of expected awards is not specified in the source information. Overall, the core message of the announcement is straightforward: it aims to spur innovative, metabolomics-based biomarker discovery projects that can move symptom science toward more objective measurement and more effective symptom management.
Frequently Asked Questions (FAQs)
What is the full title of this grant opportunity?
The opportunity is titled "Applying Metabolomics to Drive Biomarker Discovery in Symptom Science (R21)."
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PA-16-029.
Which federal agency is offering this grant?
This is a discretionary grant opportunity from the U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH). The listing is shown as HHS-NIH11.
What is the main purpose or focus of the program?
The program focuses on applying metabolomics to discover biomarkers that can improve symptom science. In practical terms, it is seeking research that identifies measurable biological signatures linked to symptoms, with the goal of improving how symptoms are understood, assessed, and managed in health and clinical care contexts.
What does "metabolomics" mean in the context of this opportunity?
Metabolomics refers to large-scale measurement and analysis of small molecules and metabolic products in biological samples. Here, metabolomics is positioned as a tool for identifying biomarker signatures connected to symptoms.
What does "biomarker discovery in symptom science" mean here?
It refers to research aimed at finding measurable biological indicators (biomarkers), such as metabolite patterns, that are linked to symptoms or symptom clusters. The intention is to support more objective measurement and more effective symptom management.
What type of grant mechanism is used?
This opportunity uses the NIH R21 mechanism.
What is the typical intent of an NIH R21 mechanism?
R21 awards are typically designed to support exploratory or early-stage projects. These projects may be higher risk but are intended to open up new directions and generate early evidence or initial findings.
What kinds of projects seem to fit the exploratory R21 emphasis described?
Based on the description provided, examples include testing novel analytical pipelines, identifying candidate metabolite patterns, or generating preliminary evidence that a metabolic signature tracks with a symptom or a symptom cluster.
What is the funding activity category listed for this opportunity?
The funding activity category is listed under Education and Health.
What CFDA numbers are associated with this announcement?
The associated CFDA numbers are 93.213 and 93.361.
Who is eligible to apply?
The eligibility is broad. Eligible applicants include:
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Federally recognized Native American tribal governments
- Other Native American tribal organizations
- Public housing authorities / Indian housing authorities
- Nonprofits with 501(c)(3) status (excluding higher education institutions in those nonprofit categories as stated)
- Nonprofits without 501(c)(3) status (excluding higher education institutions in those nonprofit categories as stated)
- For-profit organizations other than small businesses
- Small businesses
- Additional applicant types as described in the full eligibility text
Does the opportunity appear limited only to universities or medical centers?
No. The provided information describes wide eligibility intended to encourage participation from universities, medical and research centers, community-based organizations, tribal entities, and industry groups that have the technical capacity to conduct metabolomics and biomarker research.
Is this considered a discretionary grant opportunity?
Yes. It is described as a discretionary grant opportunity.
When was this opportunity created and posted?
The source data states it was created and posted on November 3, 2015.
What is the closing date for applications?
The original and current closing date listed is January 7, 2019.
What is the maximum award amount (award ceiling) listed?
The award ceiling is listed as $200,000, indicating the maximum funding limit under this announcement as presented in the provided data.
How many awards are expected?
The number of expected awards is not specified in the provided information.
What is the intended impact of the research supported by this opportunity?
The intended impact is to spur innovative metabolomics-based biomarker discovery that can move symptom science toward more objective measurement and more effective symptom management in health and clinical care settings.
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