Opportunity Information: Apply for RFA HS 10 014

  • The Agency for Health Care Research and Quality in the health recovery act sector is offering a public funding opportunity titled "ARRA OS Recovery Act 2009 Limited Competition Accelerating Implementation of Comparative Effectiveness Findings on Clinical and Delivery System Interventions by Leveraging AHRQ Networks (R18)" and is now available to receive applicants.
  • This funding opportunity was created on Feb 5, 2010 and posted on Feb 5, 2010.
  • Applicants must submit their applications by Mar 24, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $13,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $16,660,000.00 in funding.
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education State governments City or township governments Private institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments).
  • Other Eligible Applicants include the following Eligible Agencies of the Federal Government Faith based or Community based Organizations Indian/Native American Tribal Governments (Other than Federally Recognized).
Apply for RFA HS 10 014

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Opportunity Summary:

This grant opportunity (RFA-HS-10-014) was issued by the Agency for Healthcare Research and Quality (AHRQ) using American Recovery and Reinvestment Act of 2009 (ARRA) funds to speed up the real-world adoption of strong comparative effectiveness research (CER) findings. The central idea is not to fund new CER studies, but to take findings that already show measurable benefit and push them into routine practice more quickly and at a wider scale. AHRQ framed the goal broadly: implementation projects could focus on improving prevention, diagnosis, management, or treatment of a clinical condition, and they could also target system-level outcomes such as better quality of care, improved access, reduced health disparities, and stronger population health outcomes.

A key feature of the announcement is how it defines CER findings. It explicitly includes not only head-to-head clinical evidence about what works best, but also evidence about the effectiveness of implementation approaches themselves, such as behavior change methods, delivery system redesign, and other strategies recommended by the Federal Coordinating Council and the Institute of Medicine (IOM). In other words, applicants were encouraged to treat implementation as an evidence-based activity: the intervention being deployed could be a clinical practice backed by CER, and the tactics used to spread and sustain that practice could also be grounded in research on what helps organizations and clinicians change.

The FOA emphasizes dissemination and translation because HHS and AHRQ viewed that step as essential for the broader CER enterprise to actually improve care. To maximize impact, applicants were expected to leverage AHRQ-supported networks or similarly broad, multi-stakeholder or multi-site collaborations. The intention was to fund comprehensive initiatives that combine one or more interventions and practical strategies for rollout across multiple settings, rather than small pilots in a single clinic. While the notice references a list of possible interventions and strategies in the full FOA, the overall expectation is clear: projects should be designed for reach, speed, and measurable uptake, using partnerships that help implementation move beyond a single organization and into routine care across a network.

Mechanically, the funding mechanism was the R18 Research Demonstration and Dissemination grant, which typically supports applied projects that test or demonstrate how to implement proven approaches in real health care environments. The opportunity was categorized as discretionary grant funding under a health-related ARRA activity, and it did not require cost sharing or matching. The total estimated funding available was listed at $13,000,000, and the posted award ceiling was $16,660,000 (meaning the top-end possible award for a project, depending on AHRQ’s final selections and budgets).

Eligibility was broad and included many types of public and private organizations that could realistically lead multi-site implementation work. Eligible applicants included state, county, and city or township governments; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments as well as other tribal organizations; and other entities called out in the FOA such as eligible federal agencies and faith-based or community-based organizations. This mix reflects the program’s emphasis on partnerships and delivery infrastructure, since effective dissemination often requires coordination across health systems, public agencies, community organizations, and academic groups.

Important dates show that this was a time-limited ARRA opportunity with a short turnaround, consistent with Recovery Act goals of rapid action. The FOA was posted on February 5, 2010, with an application deadline of March 24, 2010, and an archive date of April 24, 2010. The full announcement was made available through the NIH grants guide platform, and technical help for accessing the electronic announcement was routed through the NIH Office of Extramural Research (OER) webmaster contacts listed in the notice.

In plain terms, this program was designed to fund fast-moving, network-driven implementation initiatives that take proven comparative effectiveness results and translate them into day-to-day clinical and system practice at scale, with an explicit focus on improving outcomes, quality, equity, and access through evidence-based change strategies.

FAQs: AHRQ Grant Opportunity RFA-HS-10-014 (ARRA Comparative Effectiveness Research Dissemination and Implementation)

What is RFA-HS-10-014?

RFA-HS-10-014 is a grant opportunity issued by the Agency for Healthcare Research and Quality (AHRQ) using American Recovery and Reinvestment Act of 2009 (ARRA) funds. It was designed to speed up real-world adoption of strong comparative effectiveness research (CER) findings by supporting dissemination, translation, and implementation activities.

What is the main purpose of this funding opportunity?

The purpose is to take CER findings that already demonstrate measurable benefit and move them into routine practice faster and at a wider scale. The focus is on implementation in real health care environments rather than generating new CER evidence.

Does this program fund new comparative effectiveness research studies?

No. The central idea is not to fund new CER studies, but to implement and spread existing CER findings that already show measurable benefit.

What types of outcomes or goals could implementation projects target?

AHRQ framed the goal broadly. Projects could focus on prevention, diagnosis, management, or treatment of a clinical condition. They could also target system-level outcomes such as improved quality of care, improved access, reduced health disparities, and stronger population health outcomes.

How does the announcement define "comparative effectiveness research (CER) findings"?

The announcement explicitly includes both (1) head-to-head clinical evidence about what works best and (2) evidence about the effectiveness of implementation approaches themselves, such as behavior change methods, delivery system redesign, and other implementation strategies recommended by the Federal Coordinating Council and the Institute of Medicine (IOM).

Can the implementation approach itself be evidence-based under this FOA?

Yes. Applicants were encouraged to treat implementation as an evidence-based activity. The clinical practice being deployed could be supported by CER, and the tactics used to spread and sustain that practice could also be grounded in research about what helps organizations and clinicians change.

What kinds of implementation strategies were emphasized?

The FOA emphasizes dissemination and translation and points to implementation strategies such as behavior change methods, delivery system redesign, and other strategies aligned with recommendations from the Federal Coordinating Council and the IOM.

What scale of project was AHRQ looking for?

The expectation was for comprehensive initiatives designed for reach, speed, and measurable uptake across multiple settings, rather than small pilots limited to a single clinic. Projects were expected to include practical rollout strategies and measurable implementation progress.

Were partnerships or networks expected?

Yes. Applicants were expected to leverage AHRQ-supported networks or similarly broad, multi-stakeholder or multi-site collaborations. The intent was to use partnerships that can move implementation beyond a single organization and into routine care across a network.

What funding mechanism was used for this opportunity?

The funding mechanism was the R18 Research Demonstration and Dissemination grant, which typically supports applied projects that demonstrate how to implement proven approaches in real health care environments.

Is this a discretionary grant?

Yes. The opportunity was categorized as discretionary grant funding under a health-related ARRA activity.

Was cost sharing or matching required?

No. The announcement states that cost sharing or matching was not required.

How much total funding was estimated to be available?

The total estimated funding available was listed at $13,000,000.

What was the posted award ceiling?

The posted award ceiling was $16,660,000, reflecting a top-end possible award for a project depending on AHRQ selections and budgets.

Who was eligible to apply?

Eligibility was broad and included many types of public and private organizations capable of leading multi-site implementation work. Eligible applicants included state, county, and city or township governments; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments and other tribal organizations; and other entities identified in the FOA such as eligible federal agencies and faith-based or community-based organizations.

Why was eligibility so broad?

The mix of eligible entities reflects the program's emphasis on partnerships and delivery infrastructure, since effective dissemination often requires coordination across health systems, public agencies, community organizations, and academic groups.

When was the FOA posted and when were applications due?

The FOA was posted on February 5, 2010. The application deadline was March 24, 2010.

When was the opportunity archived?

The archive date was April 24, 2010.

Why were the dates structured with a short turnaround?

This was described as a time-limited ARRA opportunity with a short turnaround, consistent with Recovery Act goals focused on rapid action.

Where was the full announcement made available?

The full announcement was made available through the NIH grants guide platform.

Where could applicants get technical help accessing the electronic announcement?

Technical help for accessing the electronic announcement was routed through the NIH Office of Extramural Research (OER) webmaster contacts listed in the notice.

In plain terms, what kind of project was this program trying to fund?

It was designed to fund fast-moving, network-driven implementation initiatives that translate proven CER results into day-to-day clinical and system practice at scale, with an explicit focus on improving outcomes, quality, equity, and access through evidence-based change strategies.

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