Opportunity Information: Apply for 11 534

  • The National Science Foundation in the science and technology and other research and development sector is offering a public funding opportunity titled "Assembling, Visualizing, and Analyzing the Tree of Life" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 47.074 Biological Sciences.
  • This funding opportunity was created on Apr 5, 2011 and posted on Mar 11, 2011.
  • Applicants must submit their applications by Nov 4, 2011 Full Proposal Deadline November 04, 2011 Deadline for submission of Invited Proposals. Only invited submissions will be considered for funding.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $12,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $2,000,000.00 in funding.
  • The number of recipients for this funding is limited to 6 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:

The National Science Foundation (NSF) funding opportunity "Assembling, Visualizing, and Analyzing the Tree of Life" (AVAToL; NSF Publication 11-534) is a discretionary grant program in the Biological Sciences (CFDA 47.074) aimed at pushing phylogenetics beyond separate, well-studied branches and toward a more unified, integrated tree spanning all life. Building on decades of progress since Darwin's "descent with modification" and on NSF's earlier Assembling the Tree of Life (AToL) program, AVAToL focuses on the next major bottleneck: synthesizing many partial phylogenies into a cohesive framework while also creating substantially better ways to visualize, query, and analyze an evolving, data-rich "dynamic" tree of life. The program frames this as a major scientific and technical challenge that will require conceptual leaps, potentially new kinds of characters and data, large-scale data gathering, and more powerful analytic and visualization methods than what is typically used in standard phylogenetic workflows.

A defining feature of AVAToL is that it is organized around an NSF "Ideas Lab" process rather than the traditional single-team proposal pathway. Applicants first submit a preliminary proposal in order to be considered for participation in an intensive five-day residential workshop (scheduled for August 22-26, 2011 in this solicitation). During that workshop, participants develop project concepts in real time, receive iterative feedback, and form new multidisciplinary teams on the spot. Only proposals that are invited as a result of the Ideas Lab process are eligible to be submitted as full proposals, and only invited full proposals are considered for funding. In other words, participation in the Ideas Lab is the gateway to eligibility for funding in this particular opportunity, and the program is explicitly designed to create new collaborations and high-risk, high-reward project directions that might not emerge through conventional proposal development.

Scientifically, the solicitation emphasizes two tightly linked outcomes: (1) transformative approaches to building a more integrated and robust tree of life that can reconcile and synthesize disparate phylogenetic efforts, and (2) novel tools and methods for visualization and analysis that make the resulting tree usable as a living research infrastructure. The opportunity highlights needs such as better algorithms and models, improved computational and statistical methods for inference and synthesis, scalable data pipelines, and interactive visualization systems that let researchers explore the tree, interrogate evidence, and update relationships as new data arrive. The intent is not just to add more branches to the tree, but to enable deeper integration, improved confidence and robustness, and genuinely new ways to work with tree-of-life knowledge as it grows.

Because the problems are framed as inherently cross-cutting, AVAToL strongly encourages applications from a wide range of disciplines. Alongside systematists and phylogeneticists, the NSF explicitly calls out potential contributions from mathematicians and computer scientists (for algorithms and formal models), bioinformaticians and genomicists (for pipelines and new molecular characters), morphologists and paleontologists (for phenotypic and fossil evidence that can anchor evolutionary hypotheses), statisticians (for inference frameworks and uncertainty quantification), educators (to help train the next generation of researchers in these integrated methods), and even artists or others interested in advancing visualization and interactive interfaces. The common thread is an emphasis on integrative, collaborative work that depends on sustained communication among people who do not typically share the same research toolbox.

In terms of funding details, NSF anticipated making about six awards, with an estimated total program budget of $12,000,000. Individual awards were expected to fall between $300,000 (floor) and $2,000,000 (ceiling). The funding instrument is a grant, and the solicitation includes a cost sharing or matching requirement. Eligibility is listed as unrestricted (open to any type of entity), subject to any clarifications in the full text of the announcement. Key dates in this solicitation included an original posting date of March 11, 2011; a preliminary proposal deadline of May 10, 2011 (required for Ideas Lab consideration); and a full proposal deadline of November 4, 2011 for invited proposals only.

Practical contact information in the notice points applicants to NSF's Grants.gov support channel for access issues (grantsgovsupport@nsf.gov), and the official source document is identified as NSF Publication 11-534. Overall, AVAToL is best read as an NSF attempt to catalyze a step change in how the scientific community constructs and uses the tree of life: not only improving the underlying phylogenetic synthesis across organisms, but also building the computational, statistical, and visualization infrastructure needed to explore that synthesis at scale and keep it responsive to continual scientific discovery.

Frequently Asked Questions (FAQs): NSF AVAToL (NSF Publication 11-534)

What is the AVAToL funding opportunity?

AVAToL stands for "Assembling, Visualizing, and Analyzing the Tree of Life." It is a discretionary grant opportunity from the National Science Foundation (NSF) in the Biological Sciences (CFDA 47.074) focused on advancing phylogenetics toward a more unified, integrated tree spanning all life, alongside substantially improved ways to visualize, query, and analyze that tree as a dynamic, data-rich research resource.

What is the main goal of AVAToL?

The central goal is to move beyond separate, well-studied branches of the tree of life by synthesizing many partial phylogenies into a cohesive framework. AVAToL also seeks new visualization and analysis methods that make the resulting tree usable as an evolving ("dynamic") research infrastructure that can be explored and updated as new data arrive.

How is AVAToL different from traditional NSF proposal programs?

AVAToL is organized around an NSF "Ideas Lab" process rather than the traditional single-team proposal pathway. Applicants submit a preliminary proposal to be considered for participation in an intensive five-day residential workshop. Project concepts and teams are developed during that workshop, and only proposals invited as a result of the Ideas Lab process are eligible to be submitted as full proposals.

Is participation in the Ideas Lab required to apply for funding?

Yes. Participation in the Ideas Lab is the gateway to eligibility for funding in this opportunity. Only proposals that are invited as a result of the Ideas Lab process may be submitted as full proposals, and only invited full proposals are considered for funding.

What is the first step in the application process?

The first step is submitting a preliminary proposal by the solicitation's preliminary proposal deadline. The preliminary proposal is required for consideration for participation in the Ideas Lab workshop.

What happens during the Ideas Lab workshop?

The Ideas Lab is described as an intensive five-day residential workshop where participants develop project concepts in real time, receive iterative feedback, and form new multidisciplinary teams on the spot. The program is explicitly designed to catalyze new collaborations and high-risk, high-reward project directions that may not emerge through conventional proposal development.

What are the two major scientific outcomes emphasized by the solicitation?

The solicitation emphasizes two tightly linked outcomes: (1) transformative approaches to building a more integrated and robust tree of life that can reconcile and synthesize disparate phylogenetic efforts, and (2) novel tools and methods for visualization and analysis that make the resulting tree usable as a living research infrastructure.

What types of research or development needs does AVAToL highlight?

AVAToL highlights needs including better algorithms and models, improved computational and statistical methods for inference and synthesis, scalable data pipelines, and interactive visualization systems that let researchers explore the tree, interrogate evidence, and update relationships as new data arrive.

Is AVAToL focused only on adding more species or branches to the tree of life?

No. The intent is not just to add more branches, but to enable deeper integration across disparate phylogenetic work, improve confidence and robustness, and create genuinely new ways to work with tree-of-life knowledge as it grows.

What does the solicitation mean by a "dynamic" tree of life?

The solicitation frames the tree of life as an evolving, data-rich resource that should be queryable and analyzable, with relationships that can be updated as new evidence and new data arrive, supported by improved computational, statistical, and visualization infrastructure.

What disciplines are encouraged to participate?

Because the problems are inherently cross-cutting, the solicitation strongly encourages a wide range of disciplines. It explicitly includes systematists and phylogeneticists as well as mathematicians and computer scientists, bioinformaticians and genomicists, morphologists and paleontologists, statisticians, educators, and even artists or others focused on visualization and interactive interfaces.

Why does AVAToL emphasize multidisciplinary collaboration?

The solicitation describes AVAToL's challenges as requiring conceptual leaps, potentially new kinds of characters and data, large-scale data gathering, and more powerful analytic and visualization methods than typical phylogenetic workflows. It emphasizes integrative, collaborative work that depends on sustained communication among people who do not typically share the same research toolbox.

How many awards did NSF anticipate making under this solicitation?

NSF anticipated making about six awards.

What was the estimated total program budget for AVAToL?

The estimated total program budget was $12,000,000.

What is the expected award size range for individual grants?

Individual awards were expected to range from $300,000 (floor) to $2,000,000 (ceiling).

What is the funding instrument for AVAToL?

The funding instrument is a grant.

Is there a cost sharing or matching requirement?

Yes. The solicitation includes a cost sharing or matching requirement.

Who is eligible to apply?

Eligibility is listed as unrestricted (open to any type of entity), subject to any clarifications in the full text of the announcement.

What are the key dates listed in the solicitation?

Key dates included an original posting date of March 11, 2011; a preliminary proposal deadline of May 10, 2011 (required for Ideas Lab consideration); and a full proposal deadline of November 4, 2011 for invited proposals only.

When and where was the Ideas Lab workshop scheduled (in this solicitation)?

The five-day residential workshop was scheduled for August 22-26, 2011 in this solicitation.

Can an applicant submit a full proposal without being invited from the Ideas Lab?

No. Only proposals that are invited as a result of the Ideas Lab process are eligible to be submitted as full proposals, and only invited full proposals are considered for funding.

What is the official source document identifier for this opportunity?

The official source document is NSF Publication 11-534.

Who should applicants contact for Grants.gov access issues?

Applicants are directed to NSF's Grants.gov support channel for access issues at grantsgovsupport@nsf.gov.

How does AVAToL relate to earlier NSF efforts like AToL?

AVAToL builds on decades of progress in phylogenetics and on NSF's earlier Assembling the Tree of Life (AToL) program, but it focuses on a major next bottleneck: synthesizing many partial phylogenies into a unified framework and enabling substantially better visualization and analysis of an evolving, integrated tree of life.

What kinds of methodological improvements does the solicitation suggest may be needed?

The solicitation suggests the challenge may require conceptual leaps, potentially new kinds of characters and data, large-scale data gathering, and more powerful analytical and visualization approaches than those typically used in standard phylogenetic workflows.

What does the solicitation say about the overall intent of AVAToL?

Overall, AVAToL is positioned as an NSF effort to catalyze a step change in how the scientific community constructs and uses the tree of life: improving phylogenetic synthesis across organisms while also building the computational, statistical, and visualization infrastructure needed to explore that synthesis at scale and keep it responsive to continual discovery.

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