Opportunity Information: Apply for RFA AI 10 013
Apply for RFA AI 10 013
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Asthma and Allergic Diseases Cooperative Research Centers (U19)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855 Allergy, Immunology and Transplantation Research.
- This funding opportunity was created on Jun 16, 2010 and posted on Jun 16, 2010.
- Applicants must submit their applications by Oct 7, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $12,400,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: County governments City or township governments Independent school districts State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses For profit organizations other than small businesses Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Special district governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program is a National Institutes of Health funding opportunity sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) in partnership with the Office of Research on Women's Health (ORWH). It supports coordinated, multi-project research centers focused on asthma and allergic diseases, with an emphasis on both basic and clinical research. The central goal is to deepen understanding of immune function and disease mechanisms and then move that knowledge more quickly into better ways to diagnose, treat, and prevent asthma and allergic conditions. In practical terms, the program is aimed at connecting fundamental immunology and pathobiology to real-world clinical advances, helping research teams translate discoveries into interventions that can improve patient outcomes.
This opportunity uses the U19 cooperative agreement mechanism, which is designed for multi-project, center-like awards where the NIH expects to have substantial scientific involvement during the life of the grant. Compared with a standard research project grant, a U19 typically reflects a more structured collaboration across several integrated projects and shared resources, often including coordinated management, common scientific goals, and a plan for how different subprojects will interact. The AADCRC structure is meant to promote synergy across disciplines, so that laboratory findings about immune pathways, inflammation, triggers, and biomarkers can be evaluated alongside clinical studies on diagnosis, therapy, and prevention strategies. The overall scope includes research on the immunological basis of asthma and allergic diseases, their pathobiology, and efforts to improve or develop approaches for diagnosis and clinical management.
Funding levels for this announcement were substantial for a center program. NIAID and ORWH planned to commit about $12.4 million per year under this FOA, with an anticipated total of roughly eight awards expected in fiscal year 2011. The announcement also included an Infrastructure and Opportunity Fund of up to $500,000 each year of the award, reflecting a built-in capacity for supporting shared resources, enabling new directions, or addressing emerging opportunities that arise during the project period. This kind of dedicated infrastructure funding is consistent with a cooperative center model where shared cores, enabling technologies, and cross-project coordination can be as important as the individual research aims.
The FOA is identified as RFA-AI-10-013 and falls under the Health activity category, with CFDA number 93.855 (Allergy, Immunology and Transplantation Research). It was posted on June 16, 2010, with an original and current closing date of October 7, 2010, and an archive date of November 7, 2010. The opportunity did not require cost sharing or matching, which reduces the financial barrier for eligible applicants and is typical for many NIH research funding mechanisms.
Eligibility was broad and intentionally inclusive, covering a wide range of potential research organizations and institutional arrangements. Eligible applicants included public and private institutions of higher education, nonprofits with and without 501(c)(3) status, state, county, city, township, and special district governments, independent school districts, small businesses, and for-profit organizations (including those other than small businesses). The eligibility list also extended to Native American tribal governments (federally recognized), tribal organizations (other than federally recognized governments), public housing authorities/Indian housing authorities, and U.S. territories or possessions. Additional eligibility information highlighted inclusion of Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, and eligible federal agencies. The FOA also explicitly welcomed applications from single institutions as well as consortia of institutions, reinforcing the expectation that many competitive proposals would be collaborative and multi-disciplinary.
Overall, this funding opportunity was built to sustain a national network of cooperative research centers capable of tackling complex questions in asthma and allergic disease research from multiple angles at once. By combining basic immunology, translational studies, and clinical research within coordinated U19 center grants, NIAID and ORWH sought to speed the pace at which mechanistic discoveries lead to measurable improvements in prevention, diagnosis, and treatment, while also supporting the infrastructure needed to keep these large, collaborative programs productive and adaptable over time.
Frequently Asked Questions (FAQs): Asthma and Allergic Diseases Cooperative Research Centers (AADCRC)
What is the Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program?
The AADCRC program is an NIH funding opportunity that supports coordinated, multi-project research centers focused on asthma and allergic diseases. The centers are designed to bring together basic and clinical research to deepen understanding of immune function and disease mechanisms and move discoveries more quickly into improved diagnosis, treatment, and prevention.
Which NIH institutes or offices sponsor this opportunity?
This funding opportunity is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) in partnership with the NIH Office of Research on Women's Health (ORWH).
What is the main goal of the AADCRC program?
The central goal is to connect fundamental immunology and pathobiology with real-world clinical advances, accelerating translation of mechanistic discoveries into better ways to diagnose, treat, and prevent asthma and allergic diseases and ultimately improve patient outcomes.
What funding mechanism is used for this opportunity?
The opportunity uses the U19 cooperative agreement mechanism. This is a multi-project, center-like award structure where NIH expects to have substantial scientific involvement throughout the life of the grant.
How is a U19 cooperative agreement different from a standard research project grant?
Compared with a standard research project grant, a U19 is typically more structured and designed for integrated, multi-project centers. It commonly involves several coordinated projects, shared resources, center management, common scientific goals, and an explicit plan for how subprojects interact to create synergy.
What kinds of research does the AADCRC program support?
The program supports coordinated research on the immunological basis of asthma and allergic diseases, their pathobiology, and efforts to improve or develop approaches for diagnosis and clinical management. It emphasizes both basic and clinical research and is intended to strengthen translation from discovery to intervention.
Does the program emphasize collaboration across disciplines?
Yes. The AADCRC structure is meant to promote synergy across disciplines so laboratory findings about immune pathways, inflammation, triggers, and biomarkers can be evaluated alongside clinical studies focused on diagnosis, therapy, and prevention strategies.
What is the Infrastructure and Opportunity Fund mentioned in the announcement?
The FOA included an Infrastructure and Opportunity Fund of up to $500,000 each year of the award. This built-in funding capacity is intended to support shared resources, enable new directions, and address emerging opportunities during the project period, consistent with a cooperative center model.
How much funding was planned for this FOA overall?
NIAID and ORWH planned to commit about $12.4 million per year under this funding opportunity announcement.
How many awards were anticipated?
The announcement anticipated roughly eight awards expected in fiscal year 2011.
What is the FOA identifier?
The FOA is identified as RFA-AI-10-013.
What is the activity category and CFDA number for this opportunity?
The opportunity falls under the Health activity category and lists CFDA number 93.855 (Allergy, Immunology and Transplantation Research).
When was the FOA posted and when did it close?
The FOA was posted on June 16, 2010. The original and current closing date was October 7, 2010. The archive date was November 7, 2010.
Is cost sharing or matching required?
No. The opportunity did not require cost sharing or matching.
What types of organizations were eligible to apply?
Eligibility was broad and included public and private institutions of higher education; nonprofits with and without 501(c)(3) status; state, county, city, township, and special district governments; independent school districts; small businesses; and for-profit organizations (including those other than small businesses).
Were tribal governments and tribal organizations eligible?
Yes. Eligible applicants included Native American tribal governments (federally recognized) and tribal organizations (other than federally recognized governments).
Were U.S. territories or possessions eligible to apply?
Yes. The eligibility list included U.S. territories or possessions.
Were public housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities were included in the eligibility list.
Did the FOA highlight any specific institution types as included?
Yes. Additional eligibility information highlighted inclusion of Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, and eligible federal agencies.
Could a single institution apply, or was a consortium required?
The FOA explicitly welcomed applications from both single institutions and consortia of institutions, reflecting the expectation that many proposals would be collaborative and multi-disciplinary.
What is the intended impact of funding these cooperative research centers?
The opportunity was designed to sustain a national network of cooperative research centers capable of addressing complex asthma and allergic disease research questions from multiple angles. By combining basic immunology, translational studies, and clinical research within coordinated U19 centers, the program aimed to speed progress toward measurable improvements in prevention, diagnosis, and treatment, while also supporting infrastructure to keep large collaborations productive and adaptable.
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