Opportunity Information: Apply for PAR 16 095
Apply for PAR 16 095
- The HHS-NIH11 in the education, health, income security and social services sector is offering a public funding opportunity titled "Basic Biopsychosocial Mechanisms and Processes in the Management of Chronic Conditions (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173, 93.213, 93.279, 93.361, 93.399, 93.846, 93.865, 93.866, 93.989,.
- This funding opportunity was created on Feb 11, 2016 and posted on Feb 11, 2016.
- Applicants must submit their applications by Dec 06, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The grant opportunity titled "Basic Biopsychosocial Mechanisms and Processes in the Management of Chronic Conditions (R21)" (Funding Opportunity Number PAR-16-095) is a National Institutes of Health (NIH) discretionary grant focused on advancing fundamental, early-stage research on how people manage chronic health conditions across the life course. It is centered on basic biopsychosocial mechanisms, meaning it encourages research that connects biological factors, psychological processes, and social or environmental context to explain why individuals and groups think, feel, and behave the way they do when living with and managing one or multiple chronic illnesses. Rather than funding programs that only test a specific service delivery model, this opportunity is aimed at deepening foundational understanding of the underlying processes that shape chronic disease self-management and related health behaviors.
A key emphasis of the announcement is the idea that chronic condition management does not happen in isolation. The FOA highlights the importance of studying individuals within their larger social contexts, such as families, peer networks, neighborhoods, workplaces, schools, and health systems. The intent is to stimulate inquiry into the mechanisms that influence day-to-day and long-term management behaviors, including how social relationships, cultural expectations, stressors, resources, and access to support interact with cognition, emotion, motivation, habits, and physiological responses. The broader goal is to clarify the individual and group processes that drive choices and routines that either reinforce health and wellbeing or contribute to worsening outcomes, especially over long time horizons.
The long-term public health aim described in the opportunity is to build knowledge that can ultimately improve overall human health, reduce illness and disability, and lengthen life. By identifying and characterizing the processes that support successful management of chronic conditions, the research supported by this FOA is meant to lay groundwork for future intervention development and refinement. In other words, the opportunity is geared toward building the scientific base that can later inform better strategies, tools, or interventions to help people maintain functioning and quality of life, prevent complications, and sustain healthy behaviors despite the ongoing demands of chronic disease.
This opportunity uses the NIH R21 funding mechanism, which is typically intended for exploratory or developmental research projects that may be high-risk or innovative and are designed to generate initial findings or proof-of-concept evidence. The listed award ceiling is $200,000, signaling a relatively limited budget consistent with the R21 mechanism and its purpose of supporting early, mechanism-focused work rather than large-scale clinical trials. The funding activity category is listed under Education, Health, Income Security and Social Services, reflecting the cross-cutting relevance of chronic condition management to health outcomes and broader social determinants.
Eligibility is broad and includes many types of organizations that could contribute to this line of research. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations both with and without 501(c)(3) status; for-profit organizations other than small businesses; and small businesses, along with additional eligible entities as described in NIH policy language. This wide eligibility reflects NIH interest in encouraging multidisciplinary teams and a wide range of institutional settings capable of conducting basic biopsychosocial research.
Administratively, the opportunity was posted and created on February 11, 2016, with an original and current closing date of December 6, 2016. The sponsoring agency is within the U.S. Department of Health and Human Services, National Institutes of Health (HHS-NIH11). Multiple CFDA numbers are associated with this announcement (93.173, 93.213, 93.279, 93.361, 93.399, 93.846, 93.865, 93.866, 93.989), which typically indicates participation or relevance across multiple NIH institutes, centers, or research areas connected to chronic disease, behavioral and social science, and related health research domains.
In practical terms, this FOA can be understood as an invitation to researchers to propose studies that explain "how and why" chronic condition management works the way it does, especially when people face real-world social and environmental pressures over long periods of time. The emphasis on mechanisms and processes suggests that competitive applications would likely focus on clearly defined constructs, pathways, and contextual influences, with the aim of producing insights that can be used later to design more effective, scalable approaches to supporting health and wellbeing for people living with chronic conditions.
FAQs: Basic Biopsychosocial Mechanisms and Processes in the Management of Chronic Conditions (R21) - PAR-16-095
What is the title of this grant opportunity?
The opportunity is titled "Basic Biopsychosocial Mechanisms and Processes in the Management of Chronic Conditions (R21)."
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is PAR-16-095.
Which agency sponsors this funding opportunity?
The sponsoring agency is the U.S. Department of Health and Human Services, National Institutes of Health (NIH), listed as HHS-NIH11.
What type of grant mechanism does this opportunity use?
This opportunity uses the NIH R21 mechanism, which is typically intended for exploratory or developmental research, including high-risk or innovative early-stage studies designed to generate initial findings or proof-of-concept evidence.
What is the overall purpose of this FOA?
The FOA aims to advance fundamental, early-stage research on how people manage chronic health conditions across the life course, with a focus on understanding the underlying mechanisms and processes that shape chronic disease self-management and related health behaviors.
What does "basic biopsychosocial mechanisms" mean in the context of this grant?
In this FOA, "basic biopsychosocial mechanisms" refers to research that connects biological factors, psychological processes, and social or environmental context to explain why individuals and groups think, feel, and behave the way they do when living with and managing one or multiple chronic conditions.
Is this FOA intended to fund specific service delivery programs?
No. The description emphasizes that the opportunity is not primarily aimed at funding projects that only test a specific service delivery model. Instead, it is geared toward deepening foundational understanding of the processes that shape management behaviors and outcomes.
What kinds of research questions does this opportunity encourage?
It encourages "how and why" studies that clarify mechanisms and processes involved in chronic condition management, including how day-to-day and long-term management behaviors emerge and change over time, especially under real-world social and environmental pressures.
Why does the FOA emphasize social context?
The FOA highlights that chronic condition management does not happen in isolation and encourages studying individuals within broader social contexts such as families, peer networks, neighborhoods, workplaces, schools, and health systems.
What kinds of contextual influences are specifically highlighted?
The FOA highlights influences such as social relationships, cultural expectations, stressors, resources, and access to support, and how these may interact with cognition, emotion, motivation, habits, and physiological responses.
Does the opportunity focus on short-term behaviors, long-term behaviors, or both?
Both. The FOA calls for research into mechanisms that influence day-to-day management behaviors as well as long-term management behaviors and outcomes, especially over long time horizons.
What is the long-term public health aim described by the FOA?
The long-term aim is to build knowledge that can ultimately improve overall human health, reduce illness and disability, and lengthen life by clarifying processes that support successful chronic condition management.
How is this FOA expected to contribute to future interventions?
The FOA is intended to lay groundwork for future intervention development and refinement by identifying and characterizing processes that support successful management, which can later inform better strategies, tools, or interventions.
What is the award ceiling listed for this opportunity?
The listed award ceiling is $200,000.
What does the award ceiling imply about project scope?
Based on the information provided, the $200,000 ceiling signals a relatively limited budget consistent with an R21 exploratory/developmental mechanism and its purpose of supporting early, mechanism-focused work rather than large-scale clinical trials.
What is the funding activity category for this FOA?
The funding activity category is listed under Education, Health, Income Security and Social Services.
Who is eligible to apply for this grant?
Eligibility is broad. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses, along with additional eligible entities as described in NIH policy language.
Are tribal governments and tribal organizations eligible?
Yes. Federally recognized Native American tribal governments and other tribal organizations are listed as eligible applicants.
Are small businesses eligible?
Yes. Small businesses are listed among eligible applicants.
Are for-profit organizations eligible?
Yes. For-profit organizations other than small businesses are listed as eligible, and small businesses are also listed separately as eligible.
Are nonprofit organizations required to have 501(c)(3) status?
No. The eligibility list includes nonprofit organizations with and without 501(c)(3) status.
Are educational entities eligible to apply?
Yes. Eligible applicants include independent school districts and both public/state-controlled and private institutions of higher education.
Which types of government entities are eligible?
Eligible government applicants include state governments, county governments, local governments, special district governments, and tribal governments (as listed in the eligibility section).
When was this opportunity posted and created?
The opportunity was posted and created on February 11, 2016.
What is the closing date for this FOA?
The original and current closing date listed is December 6, 2016.
Does the FOA emphasize studying management of a single chronic condition or multiple chronic conditions?
It explicitly references managing one or multiple chronic illnesses and encourages understanding of management processes in either case.
What does it mean that multiple CFDA numbers are associated with this FOA?
Based on the information provided, the presence of multiple CFDA numbers typically indicates participation or relevance across multiple NIH institutes, centers, or research areas connected to chronic disease, behavioral and social science, and related health research domains.
Which CFDA numbers are associated with this opportunity?
The CFDA numbers listed are 93.173, 93.213, 93.279, 93.361, 93.399, 93.846, 93.865, 93.866, and 93.989.
What kinds of outcomes or impacts does the FOA ultimately aim to support?
The FOA describes an ultimate aim of improving health and wellbeing, maintaining functioning and quality of life, preventing complications, sustaining healthy behaviors, and reducing illness and disability over time by building foundational knowledge about management processes.
What kinds of constructs or pathways might be important in a competitive application (based on the FOA description)?
Based on the FOA description, competitive applications would likely focus on clearly defined constructs, pathways, and contextual influences, aiming to explain underlying mechanisms linking biological, psychological, and social/environmental factors to chronic condition management behaviors and outcomes.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 16 095) also looked into and applied for these:
| Funding Opportunity |
|---|
| Obesity Policy Evaluation Research (R01) Apply for PA 16 165 Funding Number: PA 16 165 Agency: HHS-NIH11 Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplements for Research on Sleep Disturbances and Impact on Chronic Pain (Admin Supp) Apply for PA 16 164 Funding Number: PA 16 164 Agency: HHS-NIH11 Category: Education, Health, Income Security and Social Services Funding Amount: $100,000 |
| Mentored Research Scientist Development Award (Parent K01) Apply for PA 16 190 Funding Number: PA 16 190 Agency: HHS-NIH11 Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Revision Applications for U.S-South Africa Program for Collaborative Biomedical Research (U01) Apply for RFA AI 16 040 Funding Number: RFA AI 16 040 Agency: HHS-NIH11 Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Revision Applications for U.S-South Africa Program for Collaborative Biomedical Research (R01) Apply for RFA AI 16 039 Funding Number: RFA AI 16 039 Agency: HHS-NIH11 Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
| Building Interdisciplinary Research Careers in Women's Health (K12) Apply for RFA OD 16 013 Funding Number: RFA OD 16 013 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $500,000 |
| BRAIN Initiative: Foundations of Non-Invasive Functional Human Brain Imaging and Recording - Bridging Scales and Modalities (R01) Apply for RFA MH 17 235 Funding Number: RFA MH 17 235 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $700,000 |
| BRAIN Initiative: New Concepts and Early-Stage Research for Large-Scale Recording and Modulation in the Nervous System (R21) Apply for RFA EY 17 001 Funding Number: RFA EY 17 001 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
| BRAIN Initiative: Exploratory Targeted BRAIN Circuits Projects - eTargetedBCP (R21) Apply for RFA NS 17 015 Funding Number: RFA NS 17 015 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
| Administrative Supplements for Research on Sexual and Gender Minority (SGM) Populations (Admin Supp) Apply for PA 17 098 Funding Number: PA 17 098 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $100,000 |
| BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs - eTeamBCP (U01) Apply for RFA NS 18 008 Funding Number: RFA NS 18 008 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (U01) Apply for RFA NS 18 010 Funding Number: RFA NS 18 010 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs - eTeamBCP (U01 Clinical Trial Not Allowed) Apply for RFA NS 18 029 Funding Number: RFA NS 18 029 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Team-Research BRAIN Circuit Programs - TeamBCP (U19 Clinical Trial Required) Apply for RFA NS 19 002 Funding Number: RFA NS 19 002 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Team-Research BRAIN Circuit Programs - TeamBCP (U19 Clinical Trial Not Allowed) Apply for RFA NS 19 003 Funding Number: RFA NS 19 003 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| HEAL Initiative: Back Pain Consortium (BACPAC) Research Program: Phase 2 Clinical Trials (UG3/UH3 Clinical Trial Required) Apply for RFA AR 19 029 Funding Number: RFA AR 19 029 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
| HEAL Initiative: Coordinating Center to Support NIDA Preventing Opioid Use Disorder in Older Adolescents and Young Adults (ages 1630) Initiative (U24 Clinical Trial Not Allowed) Apply for RFA DA 19 034 Funding Number: RFA DA 19 034 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $1,500,000 |
| Medical Rehabilitation Research Resource (P2C Clinical Trial Optional) Apply for RFA HD 20 004 Funding Number: RFA HD 20 004 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition for Adolescent Brain Cognitive Development (ABCD) Study - Data Analysis, Informatics and Resource Center (U24 Clinical Trial Not Allowed) Apply for RFA DA 20 003 Funding Number: RFA DA 20 003 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition for Adolescent Brain Cognitive Development (ABCD) Study - Coordinating Center (U24 Clinical Trial Not Allowed) Apply for RFA DA 20 004 Funding Number: RFA DA 20 004 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
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