Opportunity Information: Apply for PAR 09 161
Apply for PAR 09 161
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Basic Cancer Research in Cancer Health Disparities (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research 93.396 Cancer Biology Research 93.399 Cancer Control.
- This funding opportunity was created on Mar 16, 2011 and posted on Apr 16, 2009.
- Applicants must submit their applications by Mar 16, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Small businesses Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Independent school districts Public and State controlled institutions of higher education County governments Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Basic Cancer Research in Cancer Health Disparities (U01) opportunity (Funding Opportunity Number PAR-09-161) is a National Institutes of Health program administered through the National Cancer Institute, specifically led by the Center to Reduce Cancer Health Disparities (CRCHD) in partnership with the Division of Cancer Biology (DCB). The central goal is to expand and strengthen basic research that explains why cancer burden differs across populations, with an emphasis on uncovering underlying causes and mechanisms that contribute to cancer health disparities. Rather than focusing on clinical service delivery or purely behavioral explanations, this announcement is aimed at biologically grounded questions, including genetic and other mechanistic factors that may influence differences in cancer incidence, progression, treatment response, and outcomes among different groups.
The scope of projects supported under this FOA is broad but clearly anchored in basic and mechanistic investigation. It explicitly supports pilot and feasibility studies, which are smaller, early-stage projects meant to generate foundational data and demonstrate whether a novel approach is workable. It also encourages the development and testing of new methodologies, which can include new laboratory techniques, analytic approaches, model systems, or measurement tools that make disparity-focused biology research more precise and reproducible. In addition, the FOA highlights secondary data analyses as eligible activities, signaling that investigators can use existing datasets or previously collected materials to answer new mechanistic questions related to disparities. Finally, it calls for innovative mechanistic studies, meaning proposals that move beyond describing differences to explaining them through biological pathways, genetic susceptibility, molecular processes, or related foundational mechanisms.
A major programmatic intent is capacity-building for the field. The FOA is designed to help grow a nationwide cohort of scientists with strong basic research expertise specifically oriented toward cancer health disparities. It emphasizes building resources and tools that can enable this research area to mature, including the creation or strengthening of biospecimen resources, cell lines, and methods. In practical terms, applicants are being encouraged not only to pursue their specific scientific questions but also to generate broadly useful assets that other disparity researchers can leverage, which can accelerate progress across multiple cancers, populations, and research teams.
The funding mechanism is an NIH Cooperative Agreement (U01). Compared to a standard research project grant, a U01 typically involves substantial programmatic involvement from the funding institute, meaning NCI staff may have an active partnership role in shaping milestones, facilitating collaborations, coordinating with related efforts, and ensuring that the work aligns with the FOA goals. This FOA is described as running in parallel with a companion announcement of identical scientific scope that uses the R21 Exploratory/Developmental mechanism (PAR-09-160). In effect, investigators could choose between a cooperative agreement pathway (U01) and an exploratory/developmental pathway (R21) depending on the scale, structure, and needs of the proposed project, with the U01 generally implying a more coordinated relationship with NCI program staff.
Awards under PAR-09-161 are contingent on the availability of funds and on the receipt of a sufficient number of meritorious applications. The announcement does not promise a fixed number of awards in the text provided; instead, it makes clear that funding decisions will depend on both budget conditions and peer review outcomes. The opportunity is categorized as discretionary, uses a cooperative agreement instrument, and is associated with multiple CFDA program areas: 93.393 (Cancer Cause and Prevention Research), 93.396 (Cancer Biology Research), and 93.399 (Cancer Control). There is no cost-sharing or matching requirement indicated, which generally means applicants are not required to contribute non-federal funds as a condition of the award.
Eligibility is expansive and includes many types of organizations. Eligible applicants include public and private institutions of higher education; public entities such as state governments, county governments, city or township governments, special district governments, and independent school districts; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (including small businesses and other for-profit entities); Native American tribal governments (federally recognized) and tribal organizations (other than federally recognized tribal governments); and additional categories noted in the eligibility information. The FOA also explicitly mentions eligibility for Alaska Native and Native Hawaiian Serving Institutions, Hispanic Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), regional organizations, eligible federal agencies, and U.S. territories or possessions. Taken together, the eligibility language reflects an intent to include institutions that are deeply connected to underserved or disparity-affected communities as well as a wide range of research-capable organizations.
Key administrative details from the source record include a posted date of April 16, 2009, with dates in the record indicating an original closing date of November 23, 2011, and an archive date of April 16, 2011 (the record also lists a current closing date of March 16, 2011, reflecting the historical nature of the listing). For applicants seeking the full announcement, the additional information link points to the NIH Grants Guide page for PAR-09-161. Contact guidance in the listing is oriented toward technical or access issues, directing users to the NIH Office of Extramural Research (OER) webmaster email for help accessing or linking to the full electronic announcement.
Overall, this FOA is best understood as an NCI-led effort to push cancer health disparities research further upstream into basic biology, while simultaneously building the people, tools, and shared research resources needed for long-term progress. It supports early-stage and methodologically innovative work, encourages the use of existing data and materials where appropriate, and uses the cooperative agreement structure to promote alignment and coordination with NCI priorities in reducing cancer health disparities.
Frequently Asked Questions (FAQs): Basic Cancer Research in Cancer Health Disparities (U01) - PAR-09-161
What is the PAR-09-161 funding opportunity?
PAR-09-161 is an NIH funding opportunity titled "Basic Cancer Research in Cancer Health Disparities (U01)." It is administered through the National Cancer Institute (NCI) and led by the Center to Reduce Cancer Health Disparities (CRCHD) in partnership with the Division of Cancer Biology (DCB).
What is the central goal of this opportunity?
The central goal is to expand and strengthen basic research that explains why cancer burden differs across populations. The emphasis is on identifying underlying causes and mechanisms that contribute to cancer health disparities.
What kinds of research questions does the FOA emphasize?
The FOA emphasizes biologically grounded, mechanistic questions. Examples include genetic and other mechanistic factors that may influence differences in cancer incidence, progression, treatment response, and outcomes among different groups.
Is this opportunity focused on clinical service delivery or behavioral interventions?
No. The focus is on upstream basic biology and mechanisms behind cancer health disparities, rather than clinical service delivery or purely behavioral explanations.
What types of projects are supported under this FOA?
The FOA supports a broad set of basic and mechanistic investigation activities, including pilot and feasibility studies, development and testing of new methodologies, secondary data analyses, and innovative mechanistic studies that explain disparities through biological pathways or molecular processes.
Are pilot and feasibility studies allowed?
Yes. The FOA explicitly supports pilot and feasibility studies, described as smaller early-stage projects intended to generate foundational data and demonstrate whether a novel approach is workable.
Does the FOA encourage developing new methods or tools?
Yes. The FOA encourages development and testing of new methodologies, including laboratory techniques, analytic approaches, model systems, or measurement tools that can make disparity-focused biology research more precise and reproducible.
Are secondary analyses of existing data eligible?
Yes. The FOA highlights secondary data analyses as eligible activities, indicating that investigators may use existing datasets or previously collected materials to answer new mechanistic questions related to cancer health disparities.
What does the FOA mean by "innovative mechanistic studies"?
It refers to studies that go beyond describing differences between populations and instead explain them through underlying biology, such as biological pathways, genetic susceptibility, molecular processes, or other foundational mechanisms.
Does this program have a capacity-building focus?
Yes. A major intent is capacity-building: helping grow a nationwide cohort of scientists with strong basic research expertise focused on cancer health disparities.
Does the FOA encourage building shared resources?
Yes. The FOA emphasizes building resources and tools that can enable the field to mature, including creating or strengthening biospecimen resources, cell lines, and methods that other researchers can leverage.
What funding mechanism is used for PAR-09-161?
The funding mechanism is an NIH Cooperative Agreement (U01).
What does it mean that this is a Cooperative Agreement (U01)?
Compared to a standard research project grant, a U01 typically includes substantial programmatic involvement from the funding institute. In this FOA, NCI staff may take an active partnership role in shaping milestones, facilitating collaborations, coordinating with related efforts, and helping ensure alignment with the FOA goals.
Is there a related or companion funding opportunity?
Yes. This FOA runs in parallel with a companion announcement of identical scientific scope that uses the R21 Exploratory/Developmental mechanism (PAR-09-160).
How is PAR-09-161 (U01) different from the companion R21 opportunity?
Based on the provided description, investigators could choose between a cooperative agreement pathway (U01) and an exploratory/developmental pathway (R21) depending on project scale, structure, and needs. The U01 generally implies a more coordinated relationship with NCI program staff.
How many awards will be made?
The provided text does not specify a fixed number of awards. It states that awards are contingent on the availability of funds and on receiving a sufficient number of meritorious applications.
What factors determine whether an award is made?
Funding decisions depend on budget availability and the peer review outcome (i.e., whether applications are deemed meritorious), as described in the listing.
Is cost-sharing or matching required?
No cost-sharing or matching requirement is indicated in the provided information, meaning applicants generally are not required to contribute non-federal funds as a condition of the award.
Which CFDA program areas are associated with this opportunity?
The listing associates this opportunity with multiple CFDA program areas: 93.393 (Cancer Cause and Prevention Research), 93.396 (Cancer Biology Research), and 93.399 (Cancer Control).
What types of organizations are eligible to apply?
Eligibility is broad and includes public and private institutions of higher education; state, county, city or township governments; special district governments; independent school districts; nonprofit organizations (with or without 501(c)(3) status); for-profit organizations (including small businesses); federally recognized Native American tribal governments; tribal organizations (other than federally recognized tribal governments); and additional categories noted in the eligibility information.
Are minority-serving and community-connected institutions explicitly included in eligibility?
Yes. The FOA explicitly mentions eligibility for Alaska Native and Native Hawaiian Serving Institutions, Hispanic Serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs), among other categories.
Are U.S. territories or possessions eligible?
Yes. The eligibility language includes U.S. territories or possessions.
Are federal agencies eligible to apply?
Yes. The eligibility information includes eligible federal agencies.
When was this opportunity posted?
The source record lists a posted date of April 16, 2009.
What are the closing date details shown in the record?
The record indicates an original closing date of November 23, 2011, and also lists a current closing date of March 16, 2011. The listing is described as historical, and the record also shows an archive date of April 16, 2011.
Where can applicants find the full official announcement?
The additional information link points to the NIH Grants Guide page for PAR-09-161.
Who should be contacted for technical or access issues related to the announcement?
The contact guidance provided is for technical or access issues and directs users to the NIH Office of Extramural Research (OER) webmaster email for help accessing or linking to the full electronic announcement.
What is the overall purpose of this FOA in the field of cancer disparities?
Overall, it is an NCI-led effort to push cancer health disparities research further upstream into basic biology while building the people, tools, and shared research resources needed for long-term progress. It supports early-stage and methodologically innovative work and encourages appropriate use of existing data and materials, using a cooperative agreement structure to promote coordination with NCI priorities in reducing cancer health disparities.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 09 161) also looked into and applied for these:
| Funding Opportunity |
|---|
| Developmental Projects in Complementary Approaches to Cancer Care and Treatment (R21) Apply for PA 09 167 Funding Number: PA 09 167 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Developmental Projects in Complementary Approaches to Cancer Care and Treatment (R03) Apply for PA 09 168 Funding Number: PA 09 168 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Minority Based Community Clinical Oncology Program (U10) Apply for RFA CA 09 023 Funding Number: RFA CA 09 023 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Renewal of Centers of Biomedical Research Excellence (COBRE)P20 Apply for PAR 09 180 Funding Number: PAR 09 180 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Centers of Biomedical Research Excellence (COBRE) Phase III Transitional Centers P30 Apply for RFA RR 09 005 Funding Number: RFA RR 09 005 Agency: National Institutes of Health Category: Education Health Funding Amount: $750,000 |
| Community Clinical Oncology Program (U10) Apply for RFA CA 09 022 Funding Number: RFA CA 09 022 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Technologies and Software to Support Integrative Cancer Biology Research (SBIR) R43/R44 Apply for PA 09 188 Funding Number: PA 09 188 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Technology Development for the Detection and Evaluation of Chemical and Biological Carcinogens (SBIR) R43/R44 Apply for PA 09 187 Funding Number: PA 09 187 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Technology for the Detection and Characterization of Low Abundance Proteins, Peptides, or micro RNAs (SBIR) R43/R44 Apply for PA 09 189 Funding Number: PA 09 189 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Integrating Translational Neuroscience and Adolescent Drug Abuse Treatment (R21) Apply for RFA DA 10 003 Funding Number: RFA DA 10 003 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| International Research Collaborations on HIV/AIDS and Drug Use (R01) Apply for RFA DA 10 008 Funding Number: RFA DA 10 008 Agency: National Institutes of Health Category: Education Health Funding Amount: $350,000 |
| Centers of Cancer Nanotechnology Excellence (CCNEs)(U54) Apply for RFA CA 09 012 Funding Number: RFA CA 09 012 Agency: National Institutes of Health Category: Education Health Funding Amount: $3,200,000 |
| Cancer Nanotechnology Platform Partnerships (U01) Apply for RFA CA 09 013 Funding Number: RFA CA 09 013 Agency: National Institutes of Health Category: Education Health Funding Amount: $400,000 |
| Biomarkers for Early Detection of Hematopoietic Malignancies (R01) Apply for PA 09 197 Funding Number: PA 09 197 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Biomarkers for Early Detection of Hematopoietic Malignancies (R21) Apply for PA 09 198 Funding Number: PA 09 198 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Identifying Non coding RNA Targets for Cancer Early Detection and Prevention (R21) Apply for PA 09 200 Funding Number: PA 09 200 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Identifying Non coding RNA Targets for Cancer Early Detection and Prevention (R01) Apply for PA 09 199 Funding Number: PA 09 199 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| The National Drug Abuse Treatment Clinical Trials Network (U10) Apply for RFA DA 10 009 Funding Number: RFA DA 10 009 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Bioenergetics, Fatigability, and Activity Limitations in Aging (R21) Apply for PA 09 191 Funding Number: PA 09 191 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Bioenergetics, Fatigability, and Activity Limitations in Aging (R01) Apply for PA 09 190 Funding Number: PA 09 190 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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