Opportunity Information: Apply for PAR 11 156

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Basic Cancer Research in Cancer Health Disparities (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research 93.396 Cancer Biology Research 93.399 Cancer Control.
  • This funding opportunity was created on Nov 23, 2011 and posted on Mar 16, 2011.
  • Applicants must submit their applications by Nov 28, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $250,000.00 in funding.
  • Eligible applicants include: City or township governments Small businesses State governments Special district governments Native American tribal governments (Federally recognized) County governments Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign (non U.S.) components of U.S. Organizations are allowed.
Apply for PAR 11 156

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Opportunity Summary:

The grant opportunity "Basic Cancer Research in Cancer Health Disparities (U01)" (Funding Opportunity Number PAR-11-156) is a National Cancer Institute (NCI) cooperative agreement intended to push forward mechanistic, basic science research that explains why certain populations experience higher cancer incidence, worse outcomes, or different responses to prevention and treatment. It is jointly backed by NCI units that focus on disparities, biology, and prevention: the Center to Reduce Cancer Health Disparities (CRCHD), the Division of Cancer Biology (DCB), and the Division of Cancer Prevention (DCP). The central goal is to move beyond describing disparities and instead investigate underlying biological and genetic mechanisms that may contribute to those differences, including foundational research that can inform prevention strategies.

A key feature of this announcement is its emphasis on innovative, hypothesis-driven mechanistic studies. Projects are expected to probe biological and/or genetic bases of cancer health disparities, which could include differences in tumor biology, host biology, inherited susceptibility, molecular pathways, biomarkers, or other mechanistic factors that plausibly help explain population-level differences in cancer risk or outcomes. The FOA explicitly leaves room for basic research that supports prevention, meaning applicants can propose laboratory or translational foundation work that strengthens prevention strategies, rather than focusing only on treatment-related biology.

Because the funding mechanism is a U01 cooperative agreement, the relationship with NIH/NCI is more collaborative than in a standard research grant. In practice, that typically means the funded investigators lead the science while NCI staff have a more active role in programmatic coordination, scientific stewardship, and helping align the work with the broader goals of building capability and resources in the field of cancer health disparities biology. The FOA also makes it clear that it is not only about single projects; it is also about strengthening the national research ecosystem by developing a cohort of scientists with deep basic-research expertise specifically focused on cancer health disparities.

Another major theme is resource and tool development that enables rigorous basic research in disparities. The announcement highlights the need for tangible, shareable research assets and methods such as biospecimens, cell lines, and specialized techniques or approaches tailored to studying disparities-relevant questions. In other words, the program is designed to support work that does not just produce findings, but also helps build the underlying infrastructure and experimental platforms the field needs to make sustained progress, particularly where appropriate samples or models have historically been limited.

From an administrative standpoint, this is a discretionary funding opportunity from the National Institutes of Health (NIH), categorized under education/health and aligned with multiple CFDA numbers: 93.393 (Cancer Cause and Prevention Research), 93.396 (Cancer Biology Research), and 93.399 (Cancer Control). There is no cost-sharing or matching requirement. The award ceiling listed is $250,000, which signals the maximum annual direct cost level referenced in the source data for this posting.

Eligibility is broad and intentionally inclusive, reflecting the disparities mission. Eligible applicants include a wide range of government entities (state, county, city/township, special district), public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), small businesses and other for-profit organizations, independent school districts, and public housing/Indian housing authorities. The eligibility language also calls out many institution types that are often central to disparities research and community-connected science, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations. Notably, non-U.S. entities (foreign organizations) are allowed, and foreign components of U.S. organizations are also permitted, along with U.S. territories or possessions and certain regional organizations. That breadth supports the program goal of building a nationwide (and potentially international) network of investigators and resources focused on the biology of cancer disparities.

In terms of timing and status, the opportunity was posted March 16, 2011, with an original closing date of November 23, 2011 and a current closing date listed as November 28, 2011 in the provided record. The archive date is December 29, 2011, indicating this specific announcement is no longer active, but the summary remains useful as a template for understanding similar NCI disparities-focused basic research initiatives.

For further details, the full announcement was hosted via the NIH Grants Guide at the link provided in the source (http://grants.nih.gov/grants/guide/pa-files/PAR-11-156.html). The contact pathway listed for access or technical issues is the NIH Office of Extramural Research (OER) Webmaster (FBOWebmaster@OD.NIH.GOV), which suggests that questions about the electronic posting or connectivity to the announcement were routed through NIH OER support rather than a single scientific/program contact in the excerpt you provided.

Frequently Asked Questions (FAQs)

What is the "Basic Cancer Research in Cancer Health Disparities (U01)" opportunity?

It is a National Cancer Institute (NCI) funding opportunity focused on mechanistic, basic science research that explains biological and/or genetic reasons why certain populations experience higher cancer incidence, worse outcomes, or different responses to prevention and treatment. The funding opportunity number is PAR-11-156, and it uses the U01 cooperative agreement mechanism.

Which NIH/NCI groups support this opportunity?

The opportunity is jointly backed by NCI units involved in disparities, biology, and prevention: the Center to Reduce Cancer Health Disparities (CRCHD), the Division of Cancer Biology (DCB), and the Division of Cancer Prevention (DCP).

What is the main goal of this grant program?

The central goal is to move beyond simply describing cancer health disparities and instead investigate underlying biological and genetic mechanisms that may contribute to population-level differences in cancer risk, outcomes, and responses to prevention and treatment. The program also aims to help build capacity and resources in the field of cancer health disparities biology.

What kinds of research does the FOA emphasize?

The FOA emphasizes innovative, hypothesis-driven, mechanistic studies. Projects are expected to probe biological and/or genetic bases of cancer health disparities, rather than being purely descriptive.

What types of mechanisms or topics are considered responsive?

Examples mentioned include differences in tumor biology, host biology, inherited susceptibility, molecular pathways, biomarkers, or other mechanistic factors that plausibly help explain population-level differences in cancer risk or outcomes.

Does the opportunity allow prevention-focused basic research?

Yes. The FOA explicitly leaves room for basic research that supports prevention. Applicants may propose laboratory or translational foundation work that strengthens prevention strategies, not only treatment-related biology.

What does it mean that this is a U01 cooperative agreement?

A U01 is a cooperative agreement, which generally means a more collaborative relationship with NIH/NCI than a standard research grant. Funded investigators lead the science, while NCI staff may play an active role in programmatic coordination, scientific stewardship, and helping align the work with broader program goals.

Is this program only about funding individual projects?

No. The description highlights that it is also about strengthening the national research ecosystem by developing a cohort of scientists with deep basic-research expertise specifically focused on the biology of cancer health disparities.

Does this opportunity support building research resources and tools?

Yes. A major theme is the development of tangible, shareable research assets and methods that enable rigorous basic research in disparities.

What kinds of resources or tools does the FOA highlight?

Examples include biospecimens, cell lines, and specialized techniques or approaches tailored to disparities-relevant research questions, particularly where appropriate samples or models have historically been limited.

Which federal agency and institute administer the funding?

This is a discretionary funding opportunity from the National Institutes of Health (NIH), administered through the National Cancer Institute (NCI).

What CFDA numbers are associated with this opportunity?

The opportunity is aligned with multiple CFDA numbers: 93.393 (Cancer Cause and Prevention Research), 93.396 (Cancer Biology Research), and 93.399 (Cancer Control).

Is cost-sharing or matching required?

No. The posting states there is no cost-sharing or matching requirement.

What is the award ceiling listed for this opportunity?

The award ceiling listed is $250,000, which in the provided record is described as the maximum annual direct cost level referenced for this posting.

Who is eligible to apply?

Eligibility is broad. Eligible applicants include many types of government entities (state, county, city/township, special district), public and private institutions of higher education, nonprofit organizations (with and without 501(c)(3) status), small businesses and other for-profit organizations, independent school districts, and public housing/Indian housing authorities.

Are minority-serving institutions and community-based organizations included in eligibility?

Yes. The eligibility language calls out institution types often central to disparities research, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations.

Are foreign (non-U.S.) organizations allowed to apply?

Yes. The information provided notes that non-U.S. entities (foreign organizations) are allowed, and foreign components of U.S. organizations are also permitted.

Are U.S. territories or regional organizations included?

Yes. The eligibility description includes U.S. territories or possessions and certain regional organizations.

When was the opportunity posted, and what were the closing dates?

The opportunity was posted on March 16, 2011. The original closing date is listed as November 23, 2011, and the current closing date in the provided record is November 28, 2011.

Is PAR-11-156 still active?

No. The archive date is December 29, 2011, which indicates this specific announcement is no longer active, even though the summary can still be useful for understanding similar NCI initiatives.

Where can the full announcement be found?

The full announcement was hosted in the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-11-156.html

Who is listed as a contact for access or technical issues?

The contact pathway listed for access or technical issues is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

Does the provided excerpt list a specific scientific or program contact?

Not in the information provided. The excerpt only lists the NIH OER Webmaster contact, which suggests questions about the electronic posting or connectivity to the announcement were routed through NIH OER support in this record.

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Applicants also applied for:

Applicants who have applied for this opportunity (PAR 11 156) also looked into and applied for these:

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Funding Number: PA 11 163
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The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R03) Apply for PA 11 164

Funding Number: PA 11 164
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Funding Number: PAR 11 167
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Limited Competition for Competitive Revision Applications to Accelerate and Enhance Collaborative Translational Science (UL1) Apply for RFA RR 11 004

Funding Number: RFA RR 11 004
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Funding Number: RFA RR 11 002
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Funding Number: RFA DA 12 005
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Funding Number: RFA RR 11 003
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Funding Number: RFA DA 12 009
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National Cooperative Drug Discovery and Development Groups (NCDDG) for the Treatment of Mental Disorders, Drug or Alcohol Addiction (UM1) Apply for PAR 11 206

Funding Number: PAR 11 206
Agency: National Institutes of Health
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National Cooperative Drug Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders, Drug or Alcohol Addiction (U19) Apply for PAR 11 207

Funding Number: PAR 11 207
Agency: National Institutes of Health
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NLM Express Research Grants in Biomedical Informatics (R01) Apply for PAR 11 208

Funding Number: PAR 11 208
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Funding Number: RFA LM 11 002
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