Opportunity Information: Apply for RFA AI 09 024
Apply for RFA AI 09 024
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Basic HIV Vaccine Discovery Research (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research.
- This funding opportunity was created on May 19, 2009 and posted on May 19, 2009.
- Applicants must submit their applications by Nov 9, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $10,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $350,000.00 in funding.
- Eligible applicants include: Independent school districts County governments Special district governments Public and State controlled institutions of higher education City or township governments Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Private institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Basic HIV Vaccine Discovery Research (R01) opportunity (Funding Opportunity Number RFA-AI-09-024) is a National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) funding announcement designed to push forward the early, foundational science needed to create an effective preventive (prophylactic) HIV-1 vaccine. The focus is explicitly on hypothesis-driven basic research that can uncover new ideas, mechanisms, targets, or strategies that ultimately inform how an optimal HIV-1 vaccine should be designed. Rather than funding late-stage product development alone, this FOA is centered on discovery science in HIV/AIDS, as well as broader virology and immunology work that directly supports the vaccine goal. A key theme is encouraging new concepts and approaches, including adapting methods that have worked well for vaccines against other infectious diseases and translating those lessons into the HIV vaccine context.
Projects supported under this announcement use the NIH Research Project Grant (R01) mechanism, which typically funds well-developed, investigator-initiated research programs with clear aims, strong scientific rationale, and rigorous experimental plans. The FOA is positioned alongside other NIAID HIV vaccine-related funding paths that use different mechanisms, specifically the Phased Innovation Awards in AIDS Vaccine Research (R21/R33) and HIVRAD (P01). In other words, this R01 opportunity serves applicants whose work is ready for a full research project structure, while related programs offer alternatives for phased, exploratory-to-development pipelines (R21/R33) or larger multi-project program structures (P01).
For funding, NIAID anticipated committing about $10 million in total costs in fiscal year 2010, with an expected range of roughly 15 to 25 awards. Actual awards were contingent on both the availability of appropriated funds and the quality and competitiveness of applications received, consistent with standard NIH practice. The announcement listed an award ceiling of $350,000 (as provided in the source information), which signals an expectation around the scale of individual budgets, although NIH awards are ultimately governed by the submitted budget, scope, and applicable NIH policies and any institute-specific constraints.
The opportunity falls under the Health funding activity category and is associated with CFDA numbers 93.855 (Allergy, Immunology and Transplantation Research) and 93.856 (Microbiology and Infectious Diseases Research). There is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of the award. This makes the program accessible to a wide range of research organizations, including those that may not have substantial discretionary resources to meet matching requirements.
Eligibility is broad and includes many types of domestic U.S. institutions and organizations, such as public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses), and multiple levels of government (state, county, city or township, special district governments, and certain housing authorities). Importantly, eligibility also extends to a range of specialized and mission-relevant entities, including federally recognized and other tribal governments and organizations, Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based and community-based organizations, U.S. territories or possessions, and even non-U.S. (foreign) organizations and regional organizations, reflecting NIH's interest in drawing from a global pool of scientific expertise where appropriate.
Key dates in the public listing show the FOA was posted and created on May 19, 2009, with an original and current closing date of November 9, 2009, and an archive date of December 10, 2009. The sponsoring agency is the National Institutes of Health, with NIAID as the institute issuing the announcement. Applicants needing technical help accessing or linking to the full announcement were directed to NIH Office of Extramural Research (OER) web support contacts. The full announcement was made available through the NIH Grants Guide at the provided link: http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-09-024.html
Frequently Asked Questions (FAQs)
What is the name of this funding opportunity?
The opportunity is titled Basic HIV Vaccine Discovery Research (R01).
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is RFA-AI-09-024.
Who is sponsoring and issuing this announcement?
The sponsoring agency is the National Institutes of Health (NIH). The institute issuing the announcement is the National Institute of Allergy and Infectious Diseases (NIAID).
What is the main purpose of this FOA?
This FOA is designed to push forward the early, foundational science needed to create an effective preventive (prophylactic) HIV-1 vaccine. The emphasis is on basic discovery research that can reveal new concepts, mechanisms, targets, or strategies that ultimately inform how an optimal HIV-1 vaccine should be designed.
What type of research is the FOA focused on?
The FOA explicitly focuses on hypothesis-driven basic research in HIV/AIDS and on broader virology and immunology work that directly supports the goal of developing an HIV-1 vaccine. It prioritizes discovery science rather than late-stage product development alone.
Does the FOA encourage new approaches or cross-disease lessons?
Yes. A key theme is encouraging new concepts and approaches, including adapting methods that have been successful for vaccines against other infectious diseases and translating those lessons into the HIV vaccine context.
What grant mechanism is used for awards under this announcement?
Projects are supported using the NIH Research Project Grant (R01) mechanism.
What does it mean that this is an R01 opportunity?
In the information provided, the R01 mechanism is described as typically supporting well-developed, investigator-initiated research programs with clear aims, a strong scientific rationale, and rigorous experimental plans. This FOA is positioned for applicants whose work is ready for a full research project structure.
How does this FOA relate to other NIAID HIV vaccine funding paths mentioned?
This FOA is presented alongside other NIAID HIV vaccine-related mechanisms, including the Phased Innovation Awards in AIDS Vaccine Research (R21/R33) and HIVRAD (P01). In the provided description, this R01 serves work ready for a full research project format, while the related programs offer alternatives such as a phased exploratory-to-development pipeline (R21/R33) or larger multi-project program structures (P01).
How much funding did NIAID anticipate committing, and when?
NIAID anticipated committing about $10 million in total costs in fiscal year 2010.
How many awards were expected?
The expected range was approximately 15 to 25 awards.
Is funding guaranteed?
No. The information provided states that actual awards were contingent on availability of appropriated funds and on the quality and competitiveness of applications received, consistent with standard NIH practice.
What is the award ceiling listed for this opportunity?
The announcement listed an award ceiling of $350,000 (as provided in the source information), signaling an expectation around the scale of individual budgets, subject to the submitted budget, scope, and applicable NIH policies and any institute-specific constraints.
What is the funding activity category?
The opportunity falls under the Health funding activity category.
Which CFDA numbers are associated with this opportunity?
This FOA is associated with CFDA numbers 93.855 (Allergy, Immunology and Transplantation Research) and 93.856 (Microbiology and Infectious Diseases Research).
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of the award.
Who is eligible to apply?
Eligibility is described as broad and includes many types of domestic U.S. institutions and organizations, such as:
- Public and private institutions of higher education
- Nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities)
- For-profit organizations (including small businesses)
- State, county, city or township governments
- Special district governments and certain housing authorities
Are tribal governments and tribal organizations eligible?
Yes. The eligibility information explicitly includes federally recognized and other tribal governments and organizations.
Are minority-serving institutions mentioned as eligible?
Yes. The eligibility list includes Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Are faith-based and community-based organizations eligible?
Yes. The eligibility description includes faith-based and community-based organizations.
Are U.S. territories or possessions eligible?
Yes. The eligibility description includes U.S. territories or possessions.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. The eligibility description explicitly extends to non-U.S. (foreign) organizations and regional organizations, reflecting an interest in drawing from a global pool of scientific expertise where appropriate.
When was this FOA posted?
The public listing shows the FOA was posted and created on May 19, 2009.
What was the closing date for applications?
The listing shows an original and current closing date of November 9, 2009.
When was the FOA archived?
The archive date shown is December 10, 2009.
Where can applicants find the full announcement?
The full announcement was made available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-09-024.html
Where were applicants directed for technical help accessing or linking to the announcement?
Applicants needing technical help were directed to the NIH Office of Extramural Research (OER) web support contacts.
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