Opportunity Information: Apply for CDC RFA GH17 1736

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Behavioral and Biological Surveillance of HIV among Key Populations to Improve HIV-related Services and Utilization in Zambia under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Aug 18, 2016.
  • Applicants must submit their applications by Oct 18, 2016 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $2,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for CDC RFA GH17 1736

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Opportunity Summary:

The grant opportunity titled "Behavioral and Biological Surveillance of HIV among Key Populations to Improve HIV-related Services and Utilization in Zambia under PEPFAR" focuses on closing a major gap in Zambia's HIV data by building a surveillance approach that specifically captures what is happening among key populations. Zambia's national HIV burden is largely described using general population surveys, with an estimated HIV prevalence of 13.3 percent among people ages 15 to 49. The problem highlighted in the announcement is that these general population data do not adequately describe HIV risk, transmission patterns, or service needs among groups that are often more vulnerable and harder to measure through standard household surveys. As a result, the FOA supports the development of a complementary surveillance system designed to generate reliable behavioral and biological data for these populations, so programs can respond based on evidence rather than assumptions.

A central purpose of the funding is to enable careful, credible measurement of both HIV infection and the behaviors and conditions that drive transmission within key populations. The opportunity emphasizes that surveillance in this area is sensitive in Zambia because some of the behaviors that increase HIV risk may be illegal under Zambian law. That legal and social context creates barriers to collecting accurate information, accessing participants safely, and protecting confidentiality. Because of that, the FOA explicitly calls for special attention to "sensitive sampling" methods and to the measurement of stigmatized or criminalized risk behaviors. In practical terms, this points to the need for surveillance methods that can reach hidden or marginalized communities, reduce fear of disclosure, and produce data that are scientifically defensible while prioritizing participant safety.

The expected value of the surveillance system is twofold. First, it is meant to provide a clearer profile of HIV transmission dynamics in Zambia by identifying HIV prevalence and associated risk patterns in key populations that are not well represented in population-based surveys. Second, it aims to translate those findings into better HIV services and improved utilization of prevention, care, and treatment. The announcement makes a point that key populations are not isolated from the rest of society; their sexual networks can overlap with the general population. Because of that interconnectedness, improving the understanding of HIV among key populations is framed not only as a targeted equity and public health priority, but also as a strategy that can help mitigate HIV transmission more broadly across Zambia.

From an implementation and policy standpoint, the FOA is positioned as a way to strengthen the evidence base for both programs and decision-makers. The data generated are intended to guide HIV programmers in targeting interventions more effectively, which can include tailoring prevention packages, improving linkage to care, and refining treatment and retention strategies for populations that may face discrimination, legal risk, or limited access to health services. The opportunity also highlights that the current lack of information represents a "void" in Zambia's HIV epidemiology knowledge base, implying that funded work should produce actionable outputs that improve national understanding and inform future resource allocation.

Administratively, this funding opportunity is offered by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), under PEPFAR, and is structured as a cooperative agreement. A cooperative agreement typically means CDC expects substantial involvement beyond simply issuing funds, such as providing technical guidance, collaboration on surveillance design, oversight of methodological rigor, and alignment with broader public health priorities. The opportunity is categorized as discretionary funding in the health activity area, with CFDA number 93.067. Eligibility is described as unrestricted, meaning a wide range of entity types may apply as long as they meet any additional requirements included in the full announcement text.

In terms of scale and competitiveness, the FOA lists an award ceiling of $2,000,000 and anticipates making one award, suggesting a single primary implementer or consortium would be selected to lead the work. The funding opportunity number is CDC RFA GH17-1736. The posting indicates it was created on August 18, 2016, with an original application closing date of October 18, 2016, and notes that electronic submissions were due by 11:59 p.m. Eastern Time on the deadline date. Overall, the opportunity is aimed at generating high-quality surveillance data for key populations in Zambia in a way that is ethically sound and operationally feasible, so HIV services and policies can be better targeted and more effective across the country.

Frequently Asked Questions (FAQs)

What is the title of this grant opportunity?

The opportunity is titled "Behavioral and Biological Surveillance of HIV among Key Populations to Improve HIV-related Services and Utilization in Zambia under PEPFAR."

What is the main goal of the funding opportunity?

The main goal is to close a major gap in Zambia's HIV data by building a complementary surveillance approach that specifically captures behavioral and biological HIV information among key populations. The intent is to produce reliable evidence that can be used to improve HIV-related services and increase utilization of prevention, care, and treatment.

Why is this surveillance needed if Zambia already has national HIV data?

Zambia's national HIV burden is largely described using general population surveys, including an estimated HIV prevalence of 13.3 percent among people ages 15 to 49. The funding opportunity explains that these general population data do not adequately describe HIV risk, transmission patterns, or service needs among key populations that are often more vulnerable and harder to measure through standard household surveys. The FOA is designed to address that limitation.

What kinds of data does the FOA want to generate?

The FOA emphasizes careful, credible measurement of both:

  • Biological data, including HIV infection (HIV prevalence) among key populations
  • Behavioral data and conditions that drive transmission, including stigmatized or criminalized risk behaviors

Who are the "key populations" referenced in the opportunity?

The opportunity states that key populations are groups that are often more vulnerable and harder to measure through standard household surveys, and that some relevant risk behaviors may be stigmatized or illegal under Zambian law. The specific key population groups are not enumerated in the provided summary.

How does the legal and social context in Zambia affect this work?

The FOA notes that surveillance is sensitive in Zambia because some behaviors that increase HIV risk may be illegal under Zambian law. This context can create barriers to collecting accurate information, accessing participants safely, and protecting confidentiality. Because of this, the FOA calls for special attention to methods and practices that reduce fear of disclosure while maintaining scientific rigor and prioritizing participant safety.

What does the FOA mean by "sensitive sampling"?

Based on the description, "sensitive sampling" refers to approaches suitable for reaching hidden or marginalized communities and for measuring stigmatized or criminalized risk behaviors in ways that are ethically sound, protect confidentiality, and still produce scientifically defensible results.

What outcomes is the surveillance system expected to support?

The expected value is described as twofold:

  1. Provide a clearer profile of HIV transmission dynamics in Zambia by identifying HIV prevalence and associated risk patterns in key populations not well represented in population-based surveys.
  2. Translate findings into better HIV services and improved utilization of prevention, care, and treatment.

How is this work expected to influence HIV services and programs?

The data are intended to strengthen the evidence base for program and policy decisions and to guide HIV programmers in targeting interventions more effectively. The FOA notes this can include tailoring prevention packages, improving linkage to care, and refining treatment and retention strategies for populations that may face discrimination, legal risk, or limited access to health services.

Does the FOA explain why key populations matter for the broader HIV epidemic?

Yes. The opportunity emphasizes that key populations are not isolated from the rest of society; their sexual networks can overlap with the general population. Improving understanding of HIV among key populations is framed as both an equity and public health priority and a strategy that can help mitigate HIV transmission more broadly across Zambia.

Who is the funding agency and what larger initiative is this under?

This funding opportunity is offered by the U.S. Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), under PEPFAR.

What type of award is this?

The opportunity is structured as a cooperative agreement. The description indicates this typically involves substantial CDC involvement beyond issuing funds, such as technical guidance, collaboration on surveillance design, oversight of methodological rigor, and alignment with broader public health priorities.

What is the activity area and funding category?

The opportunity is categorized as discretionary funding in the health activity area.

What is the CFDA number for this opportunity?

The CFDA number listed is 93.067.

Who is eligible to apply?

Eligibility is described as unrestricted, meaning a wide range of entity types may apply, as long as they meet any additional requirements included in the full announcement text.

How many awards does the FOA expect to make?

The FOA anticipates making one award, suggesting a single primary implementer or consortium would be selected to lead the work.

What is the maximum award amount?

The award ceiling listed is $2,000,000.

What is the funding opportunity number?

The funding opportunity number is CDC RFA GH17-1736.

When was the opportunity posted and what were the application deadlines?

The posting indicates it was created on August 18, 2016. The original application closing date was October 18, 2016, and electronic submissions were due by 11:59 p.m. Eastern Time on the deadline date.

What is the primary problem this FOA is trying to solve?

The FOA describes a "void" in Zambia's HIV epidemiology knowledge base caused by relying primarily on general population surveys that do not adequately capture HIV risk, transmission patterns, and service needs among key populations. The opportunity supports creating a complementary surveillance system to fill that gap with reliable behavioral and biological data.

What does "complementary surveillance system" mean in this context?

In this context, it means a surveillance approach designed to add to (not replace) general population survey data by generating targeted, reliable data among key populations that are not well captured by standard household surveys.

What ethical or operational considerations are highlighted?

The FOA highlights the need to prioritize participant safety and confidentiality, particularly because collecting information on stigmatized or potentially illegal behaviors can increase risks for participants. The opportunity points to the importance of methods that reduce fear of disclosure while still producing credible, high-quality data.

Is the surveillance work expected to be purely academic, or action-oriented?

The FOA frames the work as action-oriented. It emphasizes generating actionable outputs that improve national understanding and inform future resource allocation, and using evidence to improve HIV services and utilization rather than relying on assumptions.

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