Opportunity Information: Apply for PA 06 487
Apply for PA 06 487
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Behavioral and Integrative Treatment Development Program (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213 Research and Training in Complementary and Integrative Health 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Jun 3, 2009 and posted on Jul 14, 2006.
- Applicants must submit their applications by Sep 7, 2009 Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Private institutions of higher education Small businesses Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments State governments Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) For profit organizations other than small businesses Independent school districts County governments Others (see text field entitled Additional Information on Eligibility for clarification).
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
The Behavioral and Integrative Treatment Development Program (R21) is a National Institutes of Health (NIH) funding opportunity designed to spark early stage, exploratory research that can lead to real improvements in how drug and alcohol abuse and dependence are treated. The focus is on behavioral and integrative treatment research, meaning projects can center on behavioral interventions (such as counseling approaches, adherence strategies, contingency management, or other behavior change frameworks) as well as integrative approaches that may connect multiple treatment components or incorporate complementary and integrative health concepts when they are relevant to substance use treatment. The intent is practical impact: the work supported under this announcement is expected to move the field toward better, more effective, and more usable treatment options rather than remaining purely theoretical.
This program uses the NIH Exploratory/Developmental (R21) grant mechanism, which is commonly used for earlier, proof of concept, pilot, or developmental studies where investigators are testing new ideas, novel intervention strategies, innovative combinations of existing approaches, or gathering the kind of preliminary evidence needed to justify a larger clinical or effectiveness study later. The announcement notes that it runs in parallel with two companion opportunities that share the same scientific scope but use different grant mechanisms: PA 06 486 for the R01 (typically larger, more mature projects with a more extensive evidence base and longer timelines) and PA 06 488 for the R03 (often smaller scale, short pilot projects). In other words, the science area is aligned across the three announcements, while the size and maturity of the proposed work determines which mechanism is the best fit.
From a funding standpoint, awards are not guaranteed and depend on two main factors: whether funds are available and whether NIH receives enough high quality, competitive applications. The program also emphasizes that award size and project length can vary because the scope of proposed studies will differ from one application to another. Even so, the listing provides an award ceiling of 200,000, which signals the upper limit of direct costs expected under this R21 opportunity. The total number of awards and the overall dollars committed will ultimately depend on the mix of applications received, including their budgets, durations, and scientific merit.
In terms of who can apply, eligibility is broad and includes many types of organizations. Eligible applicants include public and private institutions of higher education, nonprofit organizations (both 501(c)(3) and non 501(c)(3)), small businesses and other for profit organizations (with small businesses explicitly listed but other for profits also included), and a wide range of government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. Tribal governments (federally recognized) and other Native American tribal organizations are also eligible. Beyond that, the opportunity explicitly allows foreign institutions to apply, permits eligible federal agencies to submit applications, and notes that faith based and community based organizations may apply as well. There is no cost sharing or matching requirement, which means applicants are not required to contribute non federal funds as a condition of receiving the award.
Administratively, this is a discretionary grant opportunity in the education and health funding activity area, and it is associated with CFDA numbers 93.213 (Research and Training in Complementary and Integrative Health) and 93.279 (Drug Abuse and Addiction Research Programs). The opportunity was posted on July 14, 2006, and it used multiple receipt dates rather than a single deadline, meaning NIH accepted applications at several standard submission cycles as specified in the full announcement. The record lists a current closing date of September 7, 2009, with the archive date of October 7, 2009, indicating that this particular announcement is now historical rather than active. For full details, NIH pointed applicants to the official program announcement page, and provided contact support through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.
Overall, the main point of PA 06 487 is to fund promising, developmental stage research on behavioral and integrative treatment strategies for substance use disorders, using the R21 mechanism to encourage innovative ideas that can be tested and refined, and that can later scale into more definitive trials or broader implementation efforts.
Behavioral and Integrative Treatment Development Program (R21) (PA 06 487) - FAQs
1. What is the Behavioral and Integrative Treatment Development Program (R21)?
This is an NIH funding opportunity that supports early-stage, exploratory research intended to improve treatment for drug and alcohol abuse and dependence. The program emphasizes practical impact, aiming to move treatment approaches toward being more effective and usable in real-world settings (not purely theoretical work).
2. What does "behavioral and integrative treatment" mean in this opportunity?
It refers to research focused on behavioral interventions and/or integrative approaches relevant to substance use treatment. Examples mentioned include counseling approaches, adherence strategies, contingency management, other behavior change frameworks, and integrative approaches that connect multiple treatment components or incorporate complementary and integrative health concepts when relevant.
3. What is the grant mechanism used for this program?
This opportunity uses the NIH Exploratory/Developmental (R21) mechanism, which is commonly used for early, proof-of-concept, pilot, or developmental studies where investigators are testing new ideas or gathering preliminary evidence to support larger future studies.
4. What kinds of projects are a good fit for an R21 under this announcement?
Projects that test novel intervention strategies, innovative combinations of existing approaches, or developmental concepts that need preliminary evidence before moving to a larger clinical or effectiveness study are a good fit. The supported work is expected to push toward improved treatment options for substance use disorders.
5. Is this program intended for theoretical research or practical treatment development?
The intent is practical impact. The work supported is expected to move the field toward better, more effective, and more usable treatment options rather than remaining purely theoretical.
6. Are there related NIH opportunities with the same scientific scope?
Yes. This announcement is described as running in parallel with two companion opportunities that share the same scientific scope but use different grant mechanisms: PA 06 486 (R01) and PA 06 488 (R03). The science area aligns across all three, while the appropriate mechanism depends on project size and maturity.
7. How do the companion mechanisms differ (R21 vs. R01 vs. R03) based on the description provided?
Based on the information provided: R01s are typically larger, more mature projects with a more extensive evidence base and longer timelines; R03s are often smaller-scale, short pilot projects; and R21s support exploratory/developmental work such as proof-of-concept or early testing of innovative ideas.
8. What is the maximum award amount for this R21 opportunity?
The listing provides an award ceiling of 200,000 in direct costs, indicating the upper limit of direct costs expected under this R21 opportunity.
9. Are awards guaranteed if an application is submitted?
No. Awards are not guaranteed and depend on whether funds are available and whether NIH receives enough high-quality, competitive applications.
10. Will the award size and project length be the same for every grant?
No. The program emphasizes that award size and project length can vary because proposed study scopes differ from one application to another.
11. Who is eligible to apply for this opportunity?
Eligibility is broad. Eligible applicants include public and private institutions of higher education, nonprofit organizations (501(c)(3) and non-501(c)(3)), small businesses, other for-profit organizations, and many government entities (state, county, city or township, special district governments, independent school districts, and public housing authorities/Indian housing authorities). Tribal governments (federally recognized) and other Native American tribal organizations are also eligible. Faith-based and community-based organizations may apply as well.
12. Are foreign institutions allowed to apply?
Yes. The opportunity explicitly allows foreign institutions to apply.
13. Can federal agencies apply?
Yes. The opportunity permits eligible federal agencies to submit applications.
14. Is cost sharing or matching required?
No. There is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of receiving the award.
15. What funding activity area is associated with this grant?
The opportunity is described as a discretionary grant opportunity in the education and health funding activity area.
16. What CFDA numbers are associated with this opportunity?
This opportunity is associated with CFDA 93.213 (Research and Training in Complementary and Integrative Health) and CFDA 93.279 (Drug Abuse and Addiction Research Programs).
17. When was this opportunity posted, and is it still active?
The opportunity was posted on July 14, 2006. The record lists a closing date of September 7, 2009, and an archive date of October 7, 2009, indicating this specific announcement is historical rather than active.
18. Did the opportunity have a single deadline or multiple receipt dates?
It used multiple receipt dates rather than a single deadline, meaning NIH accepted applications across several standard submission cycles as specified in the full announcement.
19. What determines how many awards NIH will make under this program?
The total number of awards and overall dollars committed depend on the mix of applications received, including their budgets, durations, and scientific merit, as well as availability of funds and the competitiveness of submissions.
20. Where were applicants directed for official details and support?
Applicants were directed to the official NIH program announcement page for full details. For access or linking issues, the information provided referenced contact support through the NIH Office of Extramural Research (OER) webmaster.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 06 487) also looked into and applied for these:
| Funding Opportunity |
|---|
| Behavioral and Integrative Treatment Development Program (R03) Apply for PA 06 488 Funding Number: PA 06 488 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Health Services Research on Practice Improvement Utilizing Community Treatment Programs within the National Drug Abuse Clinical Trials Network (CTN) (R21) Apply for PA 06 496 Funding Number: PA 06 496 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Health Services Research on Practice Improvement Utilizing Community Treatment Programs within the National Drug Abuse Clinical Trials Network (CTN) (R03) Apply for PA 06 497 Funding Number: PA 06 497 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Exfoliated Cells and Circulating DNA in Cancer Detection and Diagnosis(R21) Apply for PA 06 499 Funding Number: PA 06 499 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Pathophysiology of Bisphosphonates associated Osteonecrosis of the Jaw (R03) Apply for PA 06 502 Funding Number: PA 06 502 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Pathophysiology of Bisphosphonates associated Osteonecrosis of the Jaw (R21) Apply for PA 06 501 Funding Number: PA 06 501 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| National Cancer Institute (NCI) Cancer Education and Career Development Program (R25) Apply for PAR 06 511 Funding Number: PAR 06 511 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R21) Apply for PA 06 461 Funding Number: PA 06 461 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R33) Apply for PA 06 462 Funding Number: PA 06 462 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (Phased Innovation Award R21/R33) Apply for PA 06 463 Funding Number: PA 06 463 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R03) Apply for PAR 06 520 Funding Number: PAR 06 520 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Dissemination and Implementation Research in Health (R21) Apply for PAR 06 521 Funding Number: PAR 06 521 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Translational Research for the Prevention and Control of Diabetes and Obesity (R18) Apply for PAR 06 532 Funding Number: PAR 06 532 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Behavioral Science Track Award for Rapid Transition (B/START) (R03) Apply for PAR 06 541 Funding Number: PAR 06 541 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Development, Application, and Evaluation of Prediction Models for Cancer Risk and Prognosis (R21) Apply for PA 07 022 Funding Number: PA 07 022 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Focal Cognitive Deficits in CNS Disorders (R03) Apply for PA 07 034 Funding Number: PA 07 034 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Focal Cognitive Deficits in CNS Disorders (R21) Apply for PA 07 035 Funding Number: PA 07 035 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Discovery for Nervous System Disorders (R21) Apply for PAR 07 049 Funding Number: PAR 07 049 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Molecular genetics of drug addiction and related co morbidities (R01) Apply for PA 07 073 Funding Number: PA 07 073 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Development, Application, and Evaluation of Prediction Models for Cancer Risk and Prognosis (R01) Apply for PA 07 021 Funding Number: PA 07 021 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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