Opportunity Information: Apply for RFA MH 13 110

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Biobehavioral Research Awards for Innovative New Scientists (BRAINS) (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
  • This funding opportunity was created on Oct 21, 2013 and posted on Jun 18, 2012.
  • Applicants must submit their applications by Nov 1, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $5,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $400,000.00 in funding.
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Public and State controlled institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The Biobehavioral Research Awards for Innovative New Scientists (BRAINS) (R01) is a National Institutes of Health (NIH), National Institute of Mental Health (NIMH) grant opportunity designed to help exceptional early-career scientists launch independent, high-impact research programs in areas central to NIMH's mission. The core purpose is twofold: to fund innovative research and to accelerate the research career development of investigators who are still in the formative stages of establishing their long-term trajectories. The program is aimed at people who are committed to building a sustained research career and whose work could meaningfully reshape how mental disorders are understood, diagnosed, treated, or prevented, whether through clinical, translational, basic, or mental health services research.

A defining feature of the BRAINS program is that it is priority-driven and changes focus over time. For fiscal years 2013 and 2014, the program emphasis is tied directly to the NIMH Strategic Plan and to the Research Domain Criteria (RDoC) framework. In practical terms, this means proposed projects are expected to align with the institute's identified research priorities and gaps, and they may be particularly responsive if they adopt or inform RDoC-oriented approaches that aim to understand mental disorders through dimensions of behavior and neurobiological measures rather than only traditional diagnostic categories. The intent is to seed research directions that could be transformative for the field, not simply incremental extensions of existing work.

Administratively, this opportunity is a discretionary grant using the R01 funding mechanism, categorized under health research (CFDA 93.242, Mental Health Research Grants). The funding opportunity number is RFA-MH-13-110, and the posting date listed is June 18, 2012, with key dates indicating an original closing date of October 23, 2013, a current closing date of November 1, 2013, and an archive date of December 1, 2013. The estimated total program funding is noted as $5,000,000, with an award ceiling of $400,000. The announcement specifies no cost sharing or matching requirement, which generally reduces the need for institutional cost commitments as a condition of applying.

Eligibility includes a broad range of domestic organizations typically able to manage NIH research grants. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations both with and without 501(c)(3) status (as long as they are not institutions of higher education in the nonprofit categories listed). The eligibility language also explicitly includes several types of institutions often emphasized in federal capacity-building efforts, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian-serving Institutions. At the same time, the opportunity clearly excludes non-U.S. entities: foreign institutions are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components as defined by NIH policy are not permitted.

For applicants seeking the official details, the full announcement is available through the NIH grants guide page associated with RFA-MH-13-110. The provided contact route for access or technical problems is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV, particularly for difficulties accessing the announcement or linking to the funding notice.

Frequently Asked Questions (FAQs)

What is the BRAINS (R01) grant opportunity?

The Biobehavioral Research Awards for Innovative New Scientists (BRAINS) (R01) is a National Institutes of Health (NIH) funding opportunity from the National Institute of Mental Health (NIMH). It uses the R01 research project grant mechanism to support innovative, high-impact mental health research by exceptional early-career scientists.

What is the main purpose of the BRAINS program?

The program has two core goals: (1) to fund innovative research in areas central to NIMH's mission, and (2) to accelerate the research career development of investigators who are still in the formative stages of establishing long-term, independent research trajectories.

Who is the BRAINS program designed to support?

It is designed for exceptional early-career scientists who are committed to building a sustained research career and launching independent, high-impact research programs.

What types of research are relevant for BRAINS?

The opportunity is intended to support work that could meaningfully reshape how mental disorders are understood, diagnosed, treated, or prevented. The description indicates relevance across clinical, translational, basic, and mental health services research.

How does NIMH describe the kind of impact it is looking for?

The intent is to seed research directions that could be transformative for the field, rather than incremental extensions of existing work. Projects are expected to align with NIMH-identified research priorities and gaps.

Is the BRAINS program "priority-driven"?

Yes. A defining feature described for BRAINS is that it is priority-driven and that its focus changes over time.

What were the emphasis areas for fiscal years 2013 and 2014?

For FY 2013 and FY 2014, the emphasis is tied directly to the NIMH Strategic Plan and to the Research Domain Criteria (RDoC) framework.

What is RDoC in the context of this funding opportunity?

In the context provided, RDoC-oriented approaches aim to understand mental disorders through dimensions of behavior and neurobiological measures rather than relying only on traditional diagnostic categories. Proposed projects may be particularly responsive if they adopt or inform these approaches.

What funding mechanism does BRAINS use?

BRAINS is offered as a discretionary grant using the NIH R01 funding mechanism.

What is the CFDA number and program category for this opportunity?

The opportunity is categorized under health research with CFDA 93.242 (Mental Health Research Grants).

What is the funding opportunity number for this announcement?

The funding opportunity number is RFA-MH-13-110.

When was this funding opportunity posted?

The posting date listed is June 18, 2012.

What are the key dates (closing and archive dates) for this opportunity?

The key dates provided include an original closing date of October 23, 2013, a current closing date of November 1, 2013, and an archive date of December 1, 2013.

How much total funding is estimated for the program?

The estimated total program funding is noted as $5,000,000.

What is the award ceiling for individual awards?

The award ceiling listed is $400,000.

Is cost sharing or matching required?

No. The announcement specifies that there is no cost sharing or matching requirement.

What types of U.S. organizations are eligible to apply?

Eligibility includes domestic organizations typically able to manage NIH research grants, including public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (both with and without 501(c)(3) status) in the categories described in the opportunity.

Are minority-serving and capacity-building institutions included in the eligibility language?

Yes. The eligibility language explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian-serving Institutions.

Are foreign institutions allowed to apply?

No. Foreign institutions are not eligible to apply under this opportunity.

Are non-U.S. components of U.S. organizations eligible?

No. The opportunity states that non-U.S. components of U.S. organizations are not eligible.

Are foreign components permitted under NIH policy for this announcement?

No. The announcement indicates that foreign components, as defined by NIH policy, are not permitted.

Where can applicants find the full official announcement?

The full announcement is available through the NIH grants guide page associated with RFA-MH-13-110.

Who should be contacted for access or technical problems with the announcement link?

For difficulties accessing the announcement or linking to the funding notice, the provided contact is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

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