Opportunity Information: Apply for PAR 07 352

  • The National Institutes of Health in the education environment health income security and social services sector is offering a public funding opportunity titled "Bioengineering Research Partnerships (BRP)R01" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research.
  • This funding opportunity was created on Mar 30, 2010 and posted on Apr 6, 2007.
  • Applicants must submit their applications by Sep 7, 2010 Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $2,000,000.00 in funding.
  • Eligible applicants include: Small businesses Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities Special district governments State governments County governments.
  • Foreign institutions are not eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
Apply for PAR 07 352

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Opportunity Summary:

The Bioengineering Research Partnerships (BRP) R01 opportunity (PAR-07-352) is an NIH discretionary grant program designed to fund multi-disciplinary research teams that bring bioengineering and other quantitative sciences together with biomedical and/or clinical expertise to tackle major biological or medical problems. The core idea is a true partnership: a coordinated team using an integrative, systems-level approach to generate new knowledge or develop methods and technologies that can prevent, detect, diagnose, or treat disease, or improve understanding of health and behavior. NIH emphasizes that these projects should not be a loose collection of separate aims, but a coordinated effort with a clear leadership and management plan that explains how the team will function, make decisions, and integrate the different scientific components.

This program supports a wide range of research styles as long as they fit the partnership model and are aimed at impactful outcomes. Applicants may propose design-directed work (building and optimizing tools or systems), developmental efforts (refining early-stage approaches), discovery-driven research (finding new principles or phenomena), or hypothesis-driven studies (testing clearly defined scientific hypotheses). The research can be basic, applied, or translational, reflecting NIH interest in both foundational advances and solutions that move toward clinical or public-health impact. The announcement also allows flexibility in where the work is done: projects may be based at universities, national laboratories, medical schools, small or large businesses, and other public or private organizations, including combinations of these entities, as long as the partnership is cohesive and well-justified.

A key expectation is that each BRP will be oriented around a well-defined goal or deliverable that is realistically achievable within a 5 to 10 year horizon. The application must lay out objective milestones in the initial submission, signaling that NIH wants these projects managed with clear progress markers and accountability rather than open-ended exploration. The research plan can be up to 40 pages, and applications are reviewed using expanded review criteria suited to large, integrated, team-based bioengineering programs, meaning reviewers will weigh not only scientific merit but also the strength of integration, the partnership structure, and the feasibility of achieving the stated deliverables and milestones.

In terms of funding parameters, the opportunity lists an award ceiling of up to $2,000,000 (as presented in the source summary), and it does not require cost sharing or matching. The program spans many NIH scientific areas, reflected in the broad set of CFDA numbers associated with it, including environmental health, oral health, human genome research, communication disorders, technology innovation for human health, multiple cancer research categories, heart/lung/blood, musculoskeletal and skin diseases, neuroscience and neurological disorders, child health and development, aging, and vision research. This breadth signals that the BRP mechanism is meant to be disease-area agnostic and instead focused on the bioengineering partnership approach as the central driver of innovation.

Eligibility is broad across U.S.-based organizations and includes public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, other than institutions of higher education), small businesses and other for-profit organizations (with distinctions noted in the eligibility listing), as well as state, county, local, and special district governments, tribal governments (including federally recognized), and certain housing authorities. Faith-based and community-based organizations may apply if otherwise eligible, and eligible federal agencies may also apply. Foreign institutions are explicitly not eligible to apply, which is an important constraint for teams considering international lead applicants (though the full NIH policy details would be in the complete announcement).

The funding opportunity was posted April 6, 2007, with multiple receipt dates specified in the full announcement. The source summary lists a current closing date of September 7, 2010, with an archive date of October 7, 2010, indicating this particular announcement is historical rather than currently open. The full announcement is referenced at http://grants.nih.gov/grants/guide/pa-files/PAR-07-352.html, and NIH provides contact help through the NIH Office of Extramural Research (OER) webmaster email for access or linking issues.

Bioengineering Research Partnerships (BRP) R01 (PAR-07-352) - FAQs

What is the Bioengineering Research Partnerships (BRP) R01 program (PAR-07-352)?

The BRP R01 (PAR-07-352) is an NIH discretionary grant opportunity intended to support multi-disciplinary research teams that combine bioengineering and other quantitative sciences with biomedical and/or clinical expertise to address major biological or medical problems.

What is the central concept NIH is looking for in a BRP application?

The core idea is a true partnership: a coordinated, integrated team effort using an integrative, systems-level approach. NIH emphasizes that the project should not be a loose collection of separate aims, but a cohesive program where the different scientific components are intentionally integrated.

What types of outcomes is BRP meant to support?

Projects are expected to generate new knowledge or develop methods and technologies that can prevent, detect, diagnose, or treat disease, or improve understanding of health and behavior.

Does NIH require a leadership or management plan for the team?

Yes. NIH emphasizes the need for a clear leadership and management plan that explains how the team will function, make decisions, and integrate the different scientific components.

Is BRP limited to one specific research style (for example, hypothesis-driven research only)?

No. The program supports a range of research styles as long as they fit the partnership model and aim for impactful outcomes. Examples described include design-directed work, developmental efforts, discovery-driven research, and hypothesis-driven studies.

Can the proposed work be basic, applied, or translational?

Yes. The announcement allows basic, applied, or translational research, reflecting NIH interest in both foundational advances and approaches that move toward clinical or public-health impact.

Where can BRP projects be based?

The opportunity allows flexibility in where the work is conducted. Examples mentioned include universities, national laboratories, medical schools, small or large businesses, and other public or private organizations, including combinations of these entities, as long as the partnership is cohesive and well-justified.

What is a key expectation regarding goals or deliverables?

Each BRP is expected to be oriented around a well-defined goal or deliverable that is realistically achievable within a 5 to 10 year horizon.

Are milestones required in the application?

Yes. The application must include objective milestones in the initial submission, indicating NIH expects clear progress markers and accountability.

How long can the research plan be?

The research plan can be up to 40 pages.

How are applications reviewed under this BRP opportunity?

Applications are reviewed using expanded review criteria intended for large, integrated, team-based bioengineering programs. Reviewers weigh not only scientific merit, but also the strength of integration, the partnership structure, and the feasibility of achieving the stated deliverables and milestones.

What is the maximum funding amount mentioned for this opportunity?

The source summary lists an award ceiling of up to $2,000,000.

Is cost sharing or matching required?

No. The opportunity states that it does not require cost sharing or matching.

Is the BRP program tied to specific disease areas?

The program is described as broad and disease-area agnostic, with the bioengineering partnership approach being the central driver. The wide set of CFDA numbers associated with the opportunity signals coverage across many NIH scientific areas.

What NIH scientific areas are associated with this opportunity?

The opportunity is associated with a broad range of areas, including (as described) environmental health, oral health, human genome research, communication disorders, technology innovation for human health, multiple cancer research categories, heart/lung/blood, musculoskeletal and skin diseases, neuroscience and neurological disorders, child health and development, aging, and vision research.

Who is eligible to apply?

Eligibility is broad across U.S.-based organizations, including public and private institutions of higher education; nonprofit organizations (including those with and without 501(c)(3) status, other than institutions of higher education); small businesses and other for-profit organizations; state, county, local, and special district governments; tribal governments (including federally recognized); certain housing authorities; and eligible federal agencies.

Can faith-based or community-based organizations apply?

Yes. Faith-based and community-based organizations may apply if they are otherwise eligible.

Are foreign institutions eligible to apply as the applicant organization?

No. Foreign institutions are explicitly not eligible to apply under this opportunity.

Is this funding opportunity currently open?

Based on the information provided, this particular announcement is historical rather than currently open. It was posted April 6, 2007, with a listed closing date of September 7, 2010, and an archive date of October 7, 2010.

Where can applicants find the full funding announcement?

The full announcement is referenced at: http://grants.nih.gov/grants/guide/pa-files/PAR-07-352.html

Who can be contacted for help with access or linking issues related to the announcement?

NIH provides contact help through the NIH Office of Extramural Research (OER) webmaster email for access or linking issues.

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