Opportunity Information: Apply for PAR 16 116
Apply for PAR 16 116
- The HHS-NIH11 in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "Bioengineering Research Partnerships (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.273, 93.279, 93.286, 93.393, 93.394, 93.395, 93.399, 93.853, 93.865, 93.867,.
- This funding opportunity was created on Mar 02, 2016 and posted on Mar 02, 2016.
- Applicants must submit their applications by Jan 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
Bioengineering Research Partnerships (U01) is a National Institutes of Health (NIH) funding opportunity that supports team-based bioengineering projects aimed at turning promising tools and technologies into practical, well-characterized solutions for important biomedical problems. The emphasis is on accelerating both development and adoption, meaning the work should go beyond early concepts and toward technologies that are demonstrably robust, quantitatively understood, and positioned to fill a clear unmet need. NIH is looking for projects that can directly advance how life science processes are studied or improve the practice of medicine, with measurable gains in capability, reliability, and usefulness rather than incremental engineering tweaks.
A central feature of this program is the expectation of multidisciplinary collaboration. Competitive projects typically bring together engineers, quantitative scientists, and domain experts in biology, biomedical research, and/or clinical practice, with biomedical researchers or clinicians engaged throughout the project rather than consulted occasionally. The goal is to ensure the technology is designed around real-world scientific or medical constraints, validated in relevant settings, and guided by the needs of end users. The program encourages an integrative, quantitative bioengineering approach, which generally implies strong modeling, measurement, characterization, standards for performance, and rigorous benchmarking to demonstrate that the resulting tool or technology is reliable and broadly usable.
The award mechanism is a U01 cooperative agreement, which differs from a standard research grant in that NIH typically has substantial programmatic involvement during the life of the award. In practice, this often means closer coordination with NIH scientific staff, milestone-driven management, and periodic assessment of progress to keep the project aligned with the program’s translational objectives. The intended outcome is not simply publication, but a technology that is mature enough to be adopted by other laboratories, integrated into workflows, or advanced toward clinical and translational use, with a realistic path to impact within a medium-term timeframe. The program explicitly targets projects that can deliver meaningful solutions in roughly 5 to 10 years, signaling a focus on technologies that can plausibly reach broad utility on that horizon.
Eligibility is broad and includes many types of organizations: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses, along with other entities as allowed in the full eligibility text. This wide eligibility scope supports the partnership model by allowing academic, nonprofit, government, and industry participants to propose or join integrated development teams.
Administratively, the opportunity is issued by HHS/NIH (listed as HHS-NIH11) under Funding Opportunity Number PAR-16-116. It is categorized as a discretionary funding opportunity and uses the cooperative agreement funding instrument. The associated CFDA numbers span multiple NIH program areas (including 93.113, 93.273, 93.279, 93.286, 93.393, 93.394, 93.395, 93.399, 93.853, 93.865, and 93.867), reflecting the cross-cutting nature of bioengineering. The announcement was posted and created on March 2, 2016, with a listed closing date of January 7, 2019. Award ceiling and expected number of awards are not specified in the provided source data, so applicants would typically rely on the full FOA text and NIH institute-specific guidance for budget expectations and program scale.
Overall, this FOA funds collaborative bioengineering efforts that produce well-validated, high-impact tools or technologies, grounded in quantitative rigor and shaped continuously by biomedical and clinical stakeholders, with a clear line of sight to real adoption and measurable benefit in the 5-to-10-year window.
Frequently Asked Questions (FAQs): Bioengineering Research Partnerships (U01) - PAR-16-116
What is the Bioengineering Research Partnerships (U01) opportunity?
Bioengineering Research Partnerships (U01) is a National Institutes of Health (NIH) funding opportunity that supports team-based bioengineering projects focused on turning promising tools and technologies into practical, well-characterized solutions for important biomedical problems.
What is the main goal of this funding opportunity?
The program aims to accelerate both the development and adoption of bioengineering tools and technologies. The expectation is that projects move beyond early concepts and deliver technologies that are robust, quantitatively understood, and positioned to address a clear unmet biomedical need.
What kinds of projects are NIH looking for under this FOA?
NIH is looking for projects that can directly advance how life science processes are studied or improve the practice of medicine, with measurable gains in capability, reliability, and usefulness. The emphasis is on meaningful advances rather than incremental engineering tweaks.
Does this program support early-stage concept development?
Based on the description provided, the emphasis is not on early concepts alone. Projects are expected to progress toward technologies that are demonstrably robust, well characterized, and ready for real-world use and adoption.
What does "accelerating adoption" mean in the context of this program?
It means the work should be geared toward producing a tool or technology that other laboratories can adopt, integrate into workflows, or advance toward clinical and translational use, rather than stopping at prototype demonstration or publication.
What is the expected time-to-impact for funded projects?
The program explicitly targets projects that can deliver meaningful solutions in roughly a 5 to 10 year timeframe, indicating a focus on technologies that can plausibly reach broad utility within that horizon.
What is the award mechanism for this opportunity?
The award mechanism is a U01 cooperative agreement.
How is a U01 cooperative agreement different from a standard NIH research grant?
A U01 cooperative agreement typically involves substantial NIH programmatic involvement during the life of the award. In practice, this can include closer coordination with NIH scientific staff, milestone-driven management, and periodic assessment of progress to keep the project aligned with translational objectives.
What kind of team structure is expected for competitive applications?
A central feature of this program is multidisciplinary collaboration. Competitive projects typically bring together engineers, quantitative scientists, and domain experts in biology, biomedical research, and/or clinical practice.
How should biomedical researchers or clinicians be involved in the project?
Biomedical researchers or clinicians are expected to be engaged throughout the project rather than consulted occasionally, so the technology is designed around real-world scientific or medical constraints and guided by end-user needs.
What does NIH mean by an "integrative, quantitative bioengineering approach"?
The program encourages approaches that emphasize modeling, measurement, characterization, performance standards, and rigorous benchmarking, demonstrating that the resulting technology is reliable and broadly usable.
What types of outcomes does NIH expect from projects funded under this program?
The intended outcome is not simply publication. NIH expects a technology mature enough to be adopted by other laboratories, integrated into workflows, or advanced toward clinical and translational use, with a realistic path to impact.
What kinds of organizations are eligible to apply?
Eligibility is broad and includes: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses, along with other entities as allowed in the full eligibility text.
Can small businesses apply under this funding opportunity?
Yes. Small businesses are included in the eligibility list provided.
Can for-profit organizations apply under this funding opportunity?
Yes. For-profit organizations other than small businesses are included in the eligibility list provided.
Can academic institutions apply under this funding opportunity?
Yes. Public and state-controlled institutions of higher education and private institutions of higher education are both included in the eligibility list provided.
Can government entities apply under this funding opportunity?
Yes. The eligibility list includes multiple government entity types, including state, county, and city or township governments, as well as special district governments and independent school districts.
Can tribal governments or tribal organizations apply?
Yes. Federally recognized Native American tribal governments and other tribal organizations are included in the eligibility list provided.
Can nonprofits apply even if they do not have 501(c)(3) status?
Yes. The eligibility list includes nonprofits with or without 501(c)(3) status (other than institutions of higher education).
Who is the issuing agency for this opportunity?
The opportunity is issued by HHS/NIH (listed as HHS-NIH11).
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is PAR-16-116.
What type of funding opportunity is this?
It is categorized as a discretionary funding opportunity and uses the cooperative agreement funding instrument.
What CFDA numbers are associated with this opportunity?
The associated CFDA numbers listed are 93.113, 93.273, 93.279, 93.286, 93.393, 93.394, 93.395, 93.399, 93.853, 93.865, and 93.867.
Why are multiple CFDA numbers listed for a single opportunity?
The multiple CFDA numbers reflect the cross-cutting nature of bioengineering across multiple NIH program areas, as described in the opportunity information.
When was this announcement posted and created?
The announcement was posted and created on March 2, 2016.
What is the listed closing date for this opportunity?
The listed closing date is January 7, 2019.
Is the award ceiling specified in the provided information?
No. The award ceiling is not specified in the provided source data.
Is the expected number of awards specified in the provided information?
No. The expected number of awards is not specified in the provided source data.
Where would applicants typically look for budget expectations or program scale details?
Based on the information provided, applicants would typically rely on the full FOA text and NIH institute-specific guidance for budget expectations and the likely scale of the program.
What makes an application a strong fit for this FOA based on the description?
A strong fit is a collaborative, multidisciplinary project that applies quantitative rigor (modeling, measurement, characterization, standards, and benchmarking), is shaped continuously by biomedical and/or clinical stakeholders, targets a clear unmet need, and produces a technology positioned for real adoption and measurable benefit within about 5 to 10 years.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 16 116) also looked into and applied for these:
| Funding Opportunity |
|---|
| NIH Small Research Grant Program (Parent R03) Apply for PA 16 162 Funding Number: PA 16 162 Agency: HHS-NIH11 Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $50,000 |
| Dissemination and Implementation Research in Health (R21) Apply for PAR 16 236 Funding Number: PAR 16 236 Agency: HHS-NIH11 Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| Dissemination and Implementation Research in Health (R01) Apply for PAR 16 238 Funding Number: PAR 16 238 Agency: HHS-NIH11 Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Bioengineering Research Grants (BRG) (R01) Apply for PAR 16 242 Funding Number: PAR 16 242 Agency: HHS-NIH11 Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R03) Apply for PAR 16 237 Funding Number: PAR 16 237 Agency: HHS-NIH11 Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $50,000 |
| Small Research Grants for Establishing Basic Science-Clinical Collaborations to Understand Structural Birth Defects (R03) Apply for PAR 16 323 Funding Number: PAR 16 323 Agency: HHS-NIH11 Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $75,000 |
| Innovation Corps (I-Corps) at NIH Program for NIH and CDC Phase I Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Grantees (Admin Supp ) Apply for PA 16 414 Funding Number: PA 16 414 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $50,000 |
| NIH Blue Print: Development and Validation of Technologies for Rapid Isolation and Characterization of Extracellular Vesicles of Central Nervous System Origin (R21/R33 Clinical Trial Not Allowed) Apply for RFA MH 18 600 Funding Number: RFA MH 18 600 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| NIH Blueprint Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00) Apply for RFA NS 18 007 Funding Number: RFA NS 18 007 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Household Air Pollution (HAP) Health Outcomes Trial (UM1) Apply for RFA HL 16 012 Funding Number: RFA HL 16 012 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $5,075,000 |
| NIH Blueprint Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00) Apply for RFA NS 17 009 Funding Number: RFA NS 17 009 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ethical, Legal, and Social Implications (ELSI) of Genomics Small Research Grant Program (R03) Apply for PA 17 445 Funding Number: PA 17 445 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $50,000 |
| Ethical, Legal, and Social Implications (ELSI) of Genomics Research Project Grant Program (R01) Apply for PA 17 444 Funding Number: PA 17 444 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ethical, Legal, and Social Implications (ELSI) of Genomics Exploratory/Developmental Research Grant Program (R21) Apply for PA 17 446 Funding Number: PA 17 446 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| NIH Blueprint for Neuroscience Research: Dynamic Neuroimmune Interactions in the Transition from Normal CNS Function to Disorders (R01) Apply for RFA AA 18 007 Funding Number: RFA AA 18 007 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $400,000 |
| Research on Transgender Health (R01) Apply for PA 17 478 Funding Number: PA 17 478 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research on Transgender Health (R21) Apply for PA 17 477 Funding Number: PA 17 477 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| Innovative Approaches or Technologies to Investigate Regional, Structural and Functional Heterogeneity of CNS Small Blood and Lymphatic Vessels (R01) Apply for RFA NS 18 003 Funding Number: RFA NS 18 003 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $400,000 |
| Human Studies of Target Identification, Biomarkers and Disease Mechanisms Specific to CNS Small Blood and Lymphatic Vessels (R01) Apply for RFA NS 18 004 Funding Number: RFA NS 18 004 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $499,000 |
| Dissemination and Implementation Research in Health (R01 Clinical Trial Optional) Apply for PAR 18 007 Funding Number: PAR 18 007 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
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