Opportunity Information: Apply for RFA DA 09 022

The "Biosignatures of Chronic Drug Exposure (R21)" grant opportunity aims to support innovative projects that seek to identify biological indicators, or biosignatures, which can reveal information about an individual's past drug abuse. These biosignatures will consist of a limited number of biomarkers that are not related to central nervous system activity but can indicate changes in the brain resulting from drug use, withdrawal, or relapse.

The focus is on feasibility studies using animal models to discover clinically accessible biomaterials, such as blood or stem cells, and to identify suitable types of molecules for assay development, including proteins and RNA. The goal is to address technical challenges associated with sensitivity and predictive validity of these biosignatures.

Funded by the National Institute on Drug Abuse (NIDA), the total funding available is 2,000,000, with an expectation to make about 5 to 7 awards under the R21 grant mechanism, reflecting the high-risk nature of the research.

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Biosignatures of Chronic Drug Exposure (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
  • This funding opportunity was created on Oct 1, 2008 and posted on Oct 1, 2008.
  • Applicants must submit their applications by Jan 27, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2025.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Special district governments County governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses State governments Private institutions of higher education City or township governments Native American tribal organizations (other than Federally recognized tribal governments).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
Apply for RFA DA 09 022

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