Opportunity Information: Apply for RFA EB 13 001
Apply for RFA EB 13 001
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Blood Pressure Measurement Technologies for Low Resource Settings in the U.S. and India (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health.
- This funding opportunity was created on Jul 11, 2013 and posted on Jul 11, 2013.
- Applicants must submit their applications by Jan 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $600,000.00 in funding.
- Eligible applicants include: Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) State governments Native American tribal organizations (other than Federally recognized tribal governments) County governments City or township governments Private institutions of higher education Public and State controlled institutions of higher education Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH funding opportunity RFA-EB-13-001, titled "Blood Pressure Measurement Technologies for Low Resource Settings in the U.S. and India (U01)," is a cooperative agreement designed to spur practical technology innovation for hypertension care in settings where cost, infrastructure, and clinical staffing are limited. The central aim is to improve how high blood pressure is detected and managed in both the United States and India, with a clear emphasis on underserved populations in each country. The opportunity highlights a shared public health problem across both nations and encourages engineering and applied research solutions that can translate into real-world tools, not just laboratory concepts.
At the core of the program is the push for next-generation blood pressure measurement approaches that reduce dependence on conventional, resource-heavy methods. Traditional cuff-based devices can be a barrier in low-resource environments due to expense, maintenance needs, calibration issues, and the requirement for trained users. This funding call specifically points to the promise of new measurement technologies that could enable devices that are cuffless or otherwise less reliant on bulky or costly equipment, and that could be used accurately by people without formal medical training. The envisioned use cases include self-measurement in the home, as well as use in regional clinics or community care settings where professional staffing and equipment availability may be limited.
The mechanism is a U01 cooperative agreement, which typically means the NIH expects to have substantial scientific or programmatic involvement during the project period compared with a standard grant. In practical terms, awardees should anticipate closer coordination with the agency around milestones, progress, and project direction, reflecting the translational and implementation-oriented nature of the topic. The activity category is health-related discovery and applied research for technological innovations to improve human health, aligned with CFDA 93.286.
Funding for the initiative was estimated at a total of $2,000,000, with an award ceiling of $600,000 per award, and there is no cost-sharing or matching requirement. The opportunity was posted on July 11, 2013, with an original and current closing date of January 7, 2014, and an archive date of February 7, 2014, indicating it is no longer open but remains relevant as a model of the types of technology development priorities NIH has supported in this area.
Eligibility is broad across U.S.-based organizations and includes many government and non-government entities. Eligible applicants include state, county, and city or township governments; special district governments; public housing authorities and Indian housing authorities; independent school districts; federally recognized Native American tribal governments and other tribal organizations; public and private institutions of higher education; nonprofits both with and without 501(c)(3) status (with the latter eligible when not an institution of higher education); for-profit organizations other than small businesses; and small businesses. The notice also explicitly includes a range of mission-focused institutions and community-linked organizations, such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian Serving Institutions, and AANAPISI institutions, as well as faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible agencies of the federal government.
At the same time, the program draws clear boundaries around foreign eligibility. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. However, the announcement allows foreign components as defined in the NIH Grants Policy Statement, which generally refers to discrete elements of the project that may be carried out internationally under an otherwise eligible U.S. applicant organization. This structure fits the U.S.-India focus: it supports work that can be implemented, tested, or adapted in India through allowable foreign components while keeping the primary applicant organization within the eligible U.S. categories.
Overall, the opportunity is aimed at enabling affordable, scalable blood pressure measurement solutions that can function reliably outside high-resource clinical environments. By prioritizing devices and approaches that are easier to use, less expensive, and less dependent on specialized equipment or training, the program is positioned to improve early detection and ongoing management of hypertension. The underlying public health rationale is that better measurement access leads to earlier diagnosis, better tracking over time, and more consistent treatment decisions, which can materially reduce the burden of cardiovascular disease in both countries, especially in communities where conventional healthcare access is constrained.
FAQs: NIH RFA-EB-13-001 (U01) Blood Pressure Measurement Technologies for Low Resource Settings in the U.S. and India
What is RFA-EB-13-001?
RFA-EB-13-001 is an NIH funding opportunity titled "Blood Pressure Measurement Technologies for Low Resource Settings in the U.S. and India (U01)." It is designed to drive practical technology innovation that improves how high blood pressure (hypertension) is detected and managed in settings with limited cost, infrastructure, and clinical staffing.
What is the main goal of this funding opportunity?
The central goal is to improve blood pressure measurement and hypertension care in both the United States and India, with a strong emphasis on underserved populations. The opportunity focuses on engineering and applied research that can translate into real-world tools rather than remaining at a purely laboratory or conceptual stage.
Why does the opportunity focus on low-resource settings?
The opportunity targets environments where conventional approaches can be difficult to sustain due to expense, maintenance, calibration requirements, limited equipment availability, and a lack of trained clinical staff. The intent is to support solutions that work reliably where healthcare resources are constrained.
What kinds of technologies does NIH want to support under this program?
The opportunity emphasizes next-generation blood pressure measurement approaches that reduce dependence on traditional, resource-heavy methods. It specifically highlights the promise of new technologies that could enable cuffless devices or other approaches that are less reliant on bulky or costly equipment, while still supporting accurate measurement.
Does the opportunity specifically mention cuffless blood pressure measurement?
Yes. The announcement points to the promise of measurement technologies that could support cuffless devices (or devices that are otherwise less dependent on conventional cuff-based methods), especially for environments where cuff-based devices can be difficult to deploy and maintain.
What problems with traditional cuff-based devices does this opportunity identify?
The opportunity notes that traditional cuff-based devices can be a barrier in low-resource environments because they may be expensive, require maintenance and calibration, and often need trained users. These factors can limit widespread, reliable use outside well-resourced clinical settings.
Who are the intended users of the technologies supported by this program?
The program envisions technologies that can be used accurately by people without formal medical training. Intended users include individuals performing self-measurement at home as well as staff in regional clinics or community care settings where professional staffing and equipment may be limited.
What are the envisioned settings for using the supported technologies?
The opportunity mentions use cases such as self-measurement in the home and use in regional clinics or community care settings. The common thread is that these settings may have limited staffing, limited infrastructure, and limited access to conventional clinical equipment.
What funding mechanism is used for this opportunity?
This opportunity uses a U01 cooperative agreement mechanism.
What does a U01 cooperative agreement imply for awardees?
A U01 cooperative agreement typically means NIH expects substantial scientific or programmatic involvement during the project period compared with a standard grant. In practice, awardees should expect closer coordination with NIH around milestones, progress, and aspects of project direction, consistent with the translational and implementation-oriented nature of the work.
How much total funding was estimated for the initiative?
The initiative estimated total funding of $2,000,000.
What is the maximum award amount per award?
The award ceiling is $600,000 per award.
Is cost sharing or matching required?
No. The opportunity states there is no cost-sharing or matching requirement.
When was the opportunity posted?
The opportunity was posted on July 11, 2013.
What were the closing and archive dates?
The original and current closing date was January 7, 2014. The archive date was February 7, 2014.
Is this funding opportunity still open?
No. Based on the listed closing and archive dates, the opportunity is no longer open.
What activity category does this opportunity fall under?
The activity category is health-related discovery and applied research for technological innovations to improve human health.
What CFDA program is associated with this opportunity?
The opportunity is aligned with CFDA 93.286.
Who is eligible to apply?
Eligibility is broad across U.S.-based organizations and includes many government and non-government entities. Eligible applicants include state, county, and city or township governments; special district governments; public housing authorities and Indian housing authorities; independent school districts; federally recognized Native American tribal governments and other tribal organizations; public and private institutions of higher education; nonprofits with and without 501(c)(3) status (with the latter eligible when not an institution of higher education); for-profit organizations other than small businesses; and small businesses.
Are community-based and faith-based organizations eligible?
Yes. The opportunity explicitly includes faith-based or community-based organizations among eligible applicants.
Are minority-serving institutions specifically included in the eligibility language?
Yes. The eligibility list explicitly includes several mission-focused and community-linked institution types, including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian Serving Institutions, and AANAPISI institutions.
Are U.S. territories or possessions included as eligible applicants?
Yes. The opportunity explicitly includes U.S. territories or possessions.
Are federal agencies eligible to apply?
Yes. The opportunity includes eligible agencies of the federal government.
Are non-U.S. (foreign) institutions eligible to apply as the main applicant?
No. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply as the primary applicant organization.
Can a U.S. organization include work performed outside the United States?
The opportunity states that non-domestic components of U.S. organizations are not eligible. However, it allows foreign components as defined in the NIH Grants Policy Statement, meaning discrete elements of the project may be carried out internationally under an otherwise eligible U.S. applicant organization.
How does the U.S.-India focus fit with restrictions on foreign eligibility?
The structure supports a U.S.-based eligible applicant while allowing allowable foreign components (as defined by NIH policy). This fits a program focused on the U.S. and India by supporting work that can be implemented, tested, or adapted in India through allowable components, while keeping the applicant organization within eligible U.S. categories.
What is the overall public health rationale for focusing on measurement technology?
The opportunity is built on the idea that improving access to accurate blood pressure measurement enables earlier diagnosis, better tracking over time, and more consistent treatment decisions. This can reduce the burden of cardiovascular disease in both countries, particularly in communities where conventional healthcare access is constrained.
What kinds of outcomes is this opportunity trying to enable?
It aims to enable affordable, scalable blood pressure measurement solutions that function reliably outside high-resource clinical environments, improving detection and ongoing management of hypertension for underserved populations in the U.S. and India.
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