Opportunity Information: Apply for RFA AT 09 001

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "CAM Approaches in the Management of HIV Disease and Its Complications (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213 Research and Training in Complementary and Integrative Health.
  • This funding opportunity was created on Nov 14, 2008 and posted on Nov 14, 2008.
  • Applicants must submit their applications by Mar 27, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $400,000.00 in funding.
  • Eligible applicants include: County governments Independent school districts Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments City or township governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Special district governments Native American tribal organizations (other than Federally recognized tribal governments).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The funding opportunity titled "CAM Approaches in the Management of HIV Disease and Its Complications (R01)" (Funding Opportunity Number RFA-AT-09-001) is a National Institutes of Health (NIH) discretionary grant announcement focused on research in complementary and integrative health as it relates to HIV. The core aim is to support rigorous studies of complementary and alternative medicine (CAM) interventions that are already commonly used by people living with HIV and that are believed to help manage HIV disease itself and/or the complications that can arise from antiretroviral therapy (ART). In practical terms, the opportunity is looking for research that moves beyond anecdotal use and tests whether these complementary approaches are actually effective, and presumably safe, in addressing HIV-related symptoms, ART side effects, or other HIV-associated health complications.

This announcement uses the NIH R01 mechanism, meaning it is intended for substantial, hypothesis-driven research projects that can produce generalizable knowledge. R01s are typically used for well-developed projects with clear aims, strong preliminary rationale, and a design that can credibly answer the research questions being posed. The activity category is health, and the associated CFDA program is 93.213, Research and Training in Complementary and Integrative Health, indicating the opportunity sits within NIH's complementary and integrative health research portfolio.

For fiscal year 2009, NIH indicated an estimated total funding pool of approximately $2,000,000 for awards made under this announcement. The expectation stated in the notice was that up to four new R01 awards would be issued in FY 2009, which implies a relatively competitive program with a limited number of funded projects. The listed award ceiling is $400,000, which generally signals an upper bound on the amount that can be requested or awarded per project in some form (often per year, depending on the specific NIH budgeting instructions in the full FOA). The announcement explicitly states there is no cost sharing or matching requirement, so applicants are not expected to provide non-federal funds as a condition of eligibility.

Eligibility is broad and includes a wide range of organization types: state, county, city or township governments; special district governments; public and Indian housing authorities; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations both with and without 501(c)(3) status (with the latter category allowed when not an institution of higher education); for-profit organizations (other than small businesses); and small businesses. The eligibility section also expands to include a number of specific institution types and communities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations. Importantly, the opportunity also allows non-domestic (non-U.S.) entities (foreign organizations), regional organizations, eligible federal agencies, and U.S. territories or possessions, signaling NIH interest in a diverse applicant pool and potentially research contexts that extend beyond the continental United States.

Key dates place this as a time-limited competition that opened in late 2008 and closed in early 2009. The FOA was posted and created on November 14, 2008. The original and current closing date was March 27, 2009, and the opportunity was archived on April 27, 2009, indicating it is no longer active but remains relevant as a historical reference for the type of work NIH sought to fund under this topic area.

The overall theme of the announcement is pragmatic and patient-centered: it targets complementary interventions that people with HIV are already using or seeking out, and it asks investigators to evaluate these approaches in the context of real clinical needs, including managing HIV disease and dealing with ART-related complications. Because ART can be associated with side effects and longer-term complications, and because many patients use integrative approaches alongside conventional care, the FOA is essentially inviting well-designed research to clarify what helps, what does not, and what should be recommended or avoided based on evidence rather than assumption.

For applicants or readers seeking full details, NIH provided an official link to the complete announcement at http://grants.nih.gov/grants/guide/rfa-files/RFA-AT-09-001.html. For technical issues accessing the announcement or linking problems, the notice directs users to contact the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

Frequently Asked Questions (FAQs)

What is the title of this funding opportunity?

The opportunity is titled "CAM Approaches in the Management of HIV Disease and Its Complications (R01)."

What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number is RFA-AT-09-001.

Which agency is offering this grant opportunity?

This is a National Institutes of Health (NIH) discretionary grant announcement.

What is the main purpose of this FOA?

The FOA supports rigorous research on complementary and alternative medicine (CAM) interventions that are commonly used by people living with HIV and are believed to help manage HIV disease and/or complications associated with antiretroviral therapy (ART). The aim is to move beyond anecdotal use and test whether these complementary approaches are effective (and presumably safe) for HIV-related symptoms, ART side effects, or other HIV-associated health complications.

What types of research projects is NIH looking to fund?

The announcement is focused on well-designed, hypothesis-driven studies that can credibly evaluate CAM interventions already in common use among people with HIV, particularly where there is a practical clinical need related to HIV management or ART-related complications.

What does CAM mean in the context of this opportunity?

In this FOA, CAM refers to complementary and alternative medicine approaches, framed within NIH's complementary and integrative health research portfolio.

What grant mechanism is being used?

The FOA uses the NIH R01 mechanism.

What does the R01 mechanism imply about the expected project scope?

An R01 is intended for substantial, hypothesis-driven research projects that can produce generalizable knowledge. It is generally used for well-developed projects with clear aims, a strong rationale, and a study design capable of answering the proposed research questions.

What is the activity category for this funding opportunity?

The activity category is health.

What is the associated CFDA program number?

The CFDA program is 93.213, Research and Training in Complementary and Integrative Health.

How much total funding did NIH estimate for this program?

For fiscal year 2009, NIH estimated an approximate total funding pool of $2,000,000 for awards under this announcement.

How many awards did NIH expect to make?

NIH stated an expectation of up to four new R01 awards in FY 2009.

What is the award ceiling listed in the opportunity?

The listed award ceiling is $400,000.

Is cost sharing or matching required?

No. The announcement explicitly states there is no cost sharing or matching requirement.

Who is eligible to apply?

Eligibility is broad and includes many organization types, including: state, county, city, or township governments; special district governments; public and Indian housing authorities; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations with or without 501(c)(3) status (with the latter allowed when not an institution of higher education); for-profit organizations (other than small businesses); and small businesses.

Are specific institution types or communities highlighted as eligible?

Yes. The eligibility language includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations.

Are non-U.S. (foreign) organizations eligible to apply?

Yes. The opportunity allows non-domestic (non-U.S.) entities (foreign organizations), as well as regional organizations.

Are U.S. territories or possessions eligible?

Yes. U.S. territories or possessions are included in the eligible applicant pool.

Are federal agencies eligible to apply?

Yes. The eligibility description includes eligible federal agencies.

When was the FOA posted?

The FOA was posted and created on November 14, 2008.

What was the application closing date?

The original and current closing date listed was March 27, 2009.

Is this funding opportunity still active?

No. The opportunity was archived on April 27, 2009, indicating it is no longer active.

Why does the FOA emphasize interventions people with HIV are already using?

The FOA is described as pragmatic and patient-centered. It targets complementary interventions that people with HIV are already using or seeking out, and asks researchers to evaluate them against real clinical needs (including HIV management and ART-related complications) to clarify what helps, what does not, and what should be recommended or avoided based on evidence rather than assumption.

Where can I find the full official announcement?

The official link provided is: http://grants.nih.gov/grants/guide/rfa-files/RFA-AT-09-001.html

Who should I contact if I have technical issues accessing the FOA link?

The FOA directs users to contact the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV for technical issues or linking problems.

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