Cancer Nanotechnology Platform Partnerships (U01) | Apply Online

Opportunity Summary:

The Cancer Nanotechnology Platform Partnerships (CNPPs) (U01) funding opportunity (RFA-CA-09-013) is a National Cancer Institute (NCI), NIH cooperative agreement program meant to push forward cancer-focused nanotechnology platforms that can unlock new capabilities in basic and preclinical cancer research. The core idea is to support well-defined, “circumscribed” projects that use innovative nanotechnology approaches to tackle major barriers or fundamental questions tied to cancer biology, detection and diagnosis, prevention, or treatment. Rather than funding isolated projects, the FOA is built around multidisciplinary, team-based research where investigators can combine expertise across fields like engineering, materials science, chemistry, physics, biology, and oncology to produce transformative advances that would be difficult to achieve in a single-discipline setting.

CNPPs sit inside a larger NCI program called the NCI Alliance for Nanotechnology in Cancer (the Alliance). In that broader ecosystem, the Centers of Cancer Nanotechnology Excellence (CCNEs) function as a central infrastructure component, and the Alliance also includes two training programs. The CNPP mechanism is intended to benefit from this networked structure, with applicants encouraged to leverage the collaborative environment of the Alliance to accelerate platform development, share knowledge, and improve the odds that promising technologies can move from concept to robust preclinical proof-of-concept. A key message of the announcement is that these are “platform” projects, meaning they are expected to build or mature enabling nanotechnology capabilities that can be applied to cancer research problems, not just produce one-off experiments.

This FOA uses the U01 cooperative agreement mechanism, which typically signals substantial scientific and/or programmatic involvement by NIH staff compared with a standard grant. In practical terms, awardees should expect more active coordination with the funding institute and a stronger emphasis on collaboration, milestones, and alignment with program goals. The opportunity is categorized as discretionary funding and falls under health and education-related activity areas, with relevance across multiple CFDA listings spanning cancer cause and prevention, detection and diagnosis, treatment, biology, and control.

Eligibility is broad and includes public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profits), and state, county, city/township governments. The FOA also notes additional eligible applicants such as federal government agencies, non-U.S. (foreign) entities, regional organizations, and U.S. territories or possessions, indicating an intent to cast a wide net for strong platform concepts and capable teams. The announcement also emphasizes that participation is open to all qualified applicants, whether or not they were involved in earlier versions of the Alliance program.

Administratively, the FOA was posted in late May 2009, with an original and current closing date of October 14, 2009, and an archive date of November 14, 2009. The listed award ceiling is $400,000, and there is no cost sharing or matching requirement, which lowers barriers to participation for institutions that may not have discretionary funds to meet a match. The sponsoring agency is NIH (specifically NCI), and applicants were directed to the NIH grants guidance page for the full text of the RFA, with support contacts provided through the NIH Office of Extramural Research webmaster for access or linking issues.

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Previous opportunity: Centers of Cancer Nanotechnology Excellence (CCNEs)(U54)

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