Opportunity Information: Apply for PAR 08 055
Apply for PAR 08 055
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Cancer Prevention Research Small Grant Program (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research.
- This funding opportunity was created on Jan 6, 2009 and posted on Jan 6, 2009.
- Applicants must submit their applications by Dec 9, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses.
- Other Eligible Applicants include the following Eligible Agencies of the Federal Government Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations U.S. Territory or Possession.
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Opportunity Summary:
The Cancer Prevention Research Small Grant Program (R03), offered by the National Cancer Institute (NCI) under NIH (Funding Opportunity Number PAR-08-055), supports small, time-limited projects meant to strengthen both basic and applied research in cancer prevention. The central aim is to help investigators generate early evidence, test feasibility, or run pilot studies that can later grow into larger, more comprehensive grant applications, such as an R01. In practice, this program is positioned as a stepping stone: it funds tightly focused work that can validate a promising idea, produce preliminary data, or refine methods before scaling up to a full research project.
The scope of projects NCI is looking for is clearly centered on prevention rather than treatment. Responsive topics include the development or early testing of cancer chemoprevention agents, the discovery and validation of biomarkers that could enable earlier cancer detection, cancer-related nutrition science, and clinical prevention studies that focus on particular target organs. The announcement also allows a wide range of scientific approaches, including basic laboratory studies, translational work that bridges lab findings to clinical relevance, and human-subjects-oriented research, as long as the purpose remains prevention-focused. The emphasis is on research that can plausibly contribute to preventing cancer or catching it earlier, not on managing disease after diagnosis.
Just as important as what is included is what is explicitly excluded. Applications will be considered non-responsive if they primarily focus on treatment, metastasis, or cancer etiology, or if they are treatment-related quality-of-life population-based studies. In other words, even if a study is important, it will not fit this particular FOA if its core objective is understanding causes of cancer in populations, tracking spread of disease, improving treatment strategies, or evaluating quality of life in the context of cancer therapy. The program is narrowly aimed at prevention and early detection, and proposals need to be framed accordingly.
The FOA encourages participation from both new and established investigators, and it highlights several relevant disciplines and topic areas, such as chemoprevention, nutritional science, genetics, infectious agents, and early detection research, including biomarker development and validation. The small-grant format is especially suited for investigators who need funding to try a high-potential, innovative concept without committing to a large, long-term project right away, as well as for established researchers who want to explore a new prevention-oriented direction or generate key preliminary results.
From an administrative standpoint, this is a discretionary grant opportunity (Funding Instrument Type: Grant) in the health and education activity area, associated with CFDA 93.393 (Cancer Cause and Prevention Research). There is no cost-sharing or matching requirement. The opportunity was posted and created on January 6, 2009, with an original and current closing date of December 9, 2010, and it was archived on January 9, 2011.
Eligibility is broad and includes public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including 501(c)(3) and non-501(c)(3) entities), for-profit organizations other than small businesses, and small businesses. Additional eligible applicants also include eligible federal agencies, non-U.S. entities (foreign organizations), regional organizations, and U.S. territories or possessions. The administering agency is NIH (NCI), and the full announcement was made available through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PAR-08-055.html. For access or technical issues with the posting, the NIH Office of Extramural Research (OER) webmaster contact listed is FBOWebmaster@OD.NIH.GOV.
Overall, the R03 Cancer Prevention Research Small Grant Program is best understood as targeted seed funding for prevention-focused science, aimed at generating the kind of early findings that make larger, definitive cancer prevention and early detection studies possible.
Frequently Asked Questions (FAQs)
What is the Cancer Prevention Research Small Grant Program (R03)?
The Cancer Prevention Research Small Grant Program (R03) is a National Cancer Institute (NCI) funding opportunity that supports small, time-limited research projects in cancer prevention. It is designed to fund tightly focused work that can produce early evidence, demonstrate feasibility, or generate pilot data that can support later, larger grant applications.
What is the purpose of this R03 program?
The central purpose is to help investigators generate preliminary findings or test methods so they can build toward more comprehensive cancer prevention research projects in the future. The program is positioned as a stepping stone to larger applications, such as an R01.
Who offers and administers this grant opportunity?
This opportunity is offered by the National Cancer Institute (NCI) under the National Institutes of Health (NIH). NIH/NCI is the administering agency.
What is the Funding Opportunity Number for this announcement?
The Funding Opportunity Number is PAR-08-055.
What type of funding instrument is this?
This is a discretionary grant opportunity. The funding instrument type is a Grant.
What kinds of projects are a good fit for this FOA?
The FOA is focused on prevention and early detection research. Responsive topics include early development or testing of cancer chemoprevention agents, discovery and validation of biomarkers for earlier detection, cancer-related nutrition science, and clinical prevention studies focused on particular target organs. The FOA also allows a range of approaches (basic, translational, and human-subjects-oriented) as long as the purpose remains prevention-focused.
Does this program fund both basic and applied research?
Yes. The program is intended to strengthen both basic and applied research in cancer prevention, including basic laboratory work, translational studies, and human-subjects-oriented research, provided the focus is prevention and/or early detection.
Is this grant intended for pilot or feasibility studies?
Yes. A core aim of the program is to support early evidence generation, feasibility testing, and pilot studies that can later be expanded into larger, more definitive grant applications.
How is this R03 positioned relative to larger grants like an R01?
This R03 is described as seed funding or a stepping stone. It supports focused projects that validate ideas, refine methods, and generate preliminary data that may make future applications (such as an R01) more competitive.
What scientific areas does the FOA highlight as relevant?
The FOA highlights prevention-relevant disciplines and topic areas including chemoprevention, nutritional science, genetics, infectious agents, and early detection research such as biomarker development and validation.
What is explicitly not responsive under this FOA?
Applications will be considered non-responsive if they primarily focus on treatment, metastasis, or cancer etiology, or if they are treatment-related quality-of-life population-based studies. Even if scientifically important, projects framed mainly around those aims do not fit this prevention- and early-detection-focused FOA.
Is cancer treatment research allowed if it relates to cancer outcomes?
Based on the FOA description provided, proposals that primarily focus on treatment are non-responsive. The announcement emphasizes prevention and early detection rather than managing disease after diagnosis.
Are studies on metastasis or spread of disease appropriate for this R03?
No. The FOA states that applications primarily focused on metastasis will be considered non-responsive.
Are cancer etiology studies eligible under this FOA?
No. The FOA states that applications primarily focused on cancer etiology will be considered non-responsive.
Are quality-of-life studies eligible?
Treatment-related quality-of-life population-based studies are explicitly listed as non-responsive for this FOA.
Who is encouraged to apply?
The FOA encourages participation from both new and established investigators. It is positioned to help investigators test high-potential concepts without committing to a large, long-term project, and to help established researchers explore new prevention-oriented directions.
What organizations are eligible to apply?
Eligibility includes public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including 501(c)(3) and non-501(c)(3) entities), for-profit organizations other than small businesses, and small businesses. Additional eligible applicants include eligible federal agencies, non-U.S. entities (foreign organizations), regional organizations, and U.S territories or possessions.
Are non-U.S. (foreign) organizations eligible?
Yes. The eligibility list includes non-U.S. entities (foreign organizations).
Are small businesses eligible?
Yes. Small businesses are listed as eligible applicants.
Are for-profit organizations eligible?
Yes. For-profit organizations other than small businesses are listed as eligible, and small businesses are also listed as eligible.
Is there a cost-sharing or matching requirement?
No. The opportunity states there is no cost-sharing or matching requirement.
What is the CFDA number and program area associated with this opportunity?
This opportunity is associated with CFDA 93.393, Cancer Cause and Prevention Research, and it is in the health and education activity area.
When was this opportunity posted, and what are the close and archive dates?
The opportunity was posted and created on January 6, 2009. The original and current closing date listed is December 9, 2010. The opportunity was archived on January 9, 2011.
Where can applicants find the full announcement?
The full announcement is available through the NIH grants guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-08-055.html
Who should be contacted for access or technical issues with the posting?
For access or technical issues with the posting, the NIH Office of Extramural Research (OER) webmaster contact listed is FBOWebmaster@OD.NIH.GOV.
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