Opportunity Information: Apply for RFA CA 11 502

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Cancer Research Network a Research Resource within Health Care Delivery System (Limited Competition U24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.399 Cancer Control.
  • This funding opportunity was created on Sep 29, 2011 and posted on Sep 29, 2011.
  • Applicants must submit their applications by Dec 15, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $4,000,000.00 to eligible and selected applicants.
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following Only institutions that are current members of CRN consortium supported by the NCI U 19 cooperative agreement award are eligible to apply. Note that it is expected that all current Member institutions will participate in the CRN consortium. It is up to the discretion of eligible institutions to decide which of them will serve as applicant institution (i.e., it may be the current awardee institution or another eligible Member institution). Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Apply for RFA CA 11 502

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Opportunity Summary:

The Cancer Research Network a Research Resource within Health Care Delivery System (Limited Competition U24) opportunity (Funding Opportunity Number RFA-CA-11-502) is a National Institutes of Health initiative, led through the National Cancer Institute, designed to support the Cancer Research Network (CRN) as a shared national research resource embedded within real-world health care delivery systems. CRN is a consortium made up of research organizations housed within several non-profit Health Maintenance Organizations (HMOs). What this announcement is really doing is shifting CRN from being primarily a platform for internal, multi-site collaborative studies among its member institutions to a broader, more outward-facing resource intended to serve cancer researchers more generally. In other words, the funding is meant to strengthen and operate CRN as an infrastructure and capability that can enable a wide range of cancer research questions, not just those generated within the consortium itself.

A central theme of the FOA is that CRN offers a distinctive advantage because it sits on top of large, stable, and diverse patient populations that receive routine care through the participating HMOs, and because those delivery systems generate rich clinical data as part of everyday practice. The network’s value is not only the presence of extensive, integrated clinical datasets across multiple institutions, but also the accumulated expertise of CRN investigators and staff in how to responsibly analyze, interpret, and use large clinical data sets for cancer research. That combination positions CRN to support studies that depend on scale, longitudinal follow-up, and diversity, including questions that can be difficult to address in smaller academic cohorts or short-term clinical studies.

The award mechanism is a cooperative agreement (U24), which generally signals a resource or infrastructure-style award where the NIH expects substantial involvement and coordination with the funded group. The opportunity is categorized under health and education-related research activities and is tied to multiple cancer-related CFDA program areas, including cancer cause and prevention (93.393), detection and diagnosis (93.394), treatment (93.395), and cancer control (93.399). There is no cost-sharing or matching requirement, which means applicants are not required to commit non-federal funds as a condition of the award.

Eligibility is intentionally narrow because this is described as a limited competition. Only institutions that are current members of the CRN consortium supported by the NCI U19 cooperative agreement are allowed to apply. The FOA also makes it clear that, while one member institution will submit the application as the lead applicant, it is expected that all current CRN member institutions will participate in the consortium activities supported by this award. Which specific institution serves as the applicant is left to the discretion of the eligible members, meaning it could be the current awardee institution or another qualifying CRN member. Foreign institutions are explicitly ineligible, and foreign components of U.S. organizations are not permitted under this announcement.

From an administrative standpoint, the FOA was posted on September 29, 2011, with an original and current closing date of December 15, 2011, and an archive date of January 15, 2012. The estimated total funding listed is $4,000,000. The full announcement was made available through the NIH grants guide, and the contact listed for access or linking issues is the NIH Office of Extramural Research webmaster (FBOWebmaster@OD.NIH.GOV). Overall, the opportunity is best understood as continued federal support to operate and expand CRN as a high-value, health-system-based cancer research resource, emphasizing both data access across multiple integrated care organizations and the practical expertise needed to turn those data into credible, impactful cancer research.

Frequently Asked Questions (FAQs)

What is the funding opportunity called?

The opportunity is titled "The Cancer Research Network a Research Resource within Health Care Delivery System (Limited Competition U24)." The Funding Opportunity Number (FON) is RFA-CA-11-502.

Which federal agency is offering this opportunity?

This is a National Institutes of Health (NIH) initiative led through the National Cancer Institute (NCI).

What is the Cancer Research Network (CRN) in this announcement?

CRN is described as a shared national research resource embedded within real-world health care delivery systems. It is a consortium of research organizations housed within several non-profit Health Maintenance Organizations (HMOs).

What is the main purpose of this FOA?

The FOA is intended to support and strengthen CRN as an infrastructure and capability that can enable a wide range of cancer research questions. It reflects a shift from CRN being primarily a platform for internal, multi-site studies among member institutions to a broader, outward-facing resource meant to serve cancer researchers more generally.

What makes CRN distinctive as a research resource?

The FOA emphasizes that CRN sits on top of large, stable, and diverse patient populations receiving routine care through participating HMOs. Those delivery systems generate rich clinical data through everyday practice. In addition to the data itself, CRN brings accumulated expertise from its investigators and staff in responsibly analyzing, interpreting, and using large clinical datasets for cancer research.

What kinds of research does CRN enable according to the FOA?

CRN is positioned to support studies that depend on scale, longitudinal follow-up, and diversity. The FOA highlights that CRN can support research questions that may be difficult to address in smaller academic cohorts or short-term clinical studies.

What is the award mechanism for this opportunity?

The award mechanism is a cooperative agreement (U24). This generally indicates a resource or infrastructure-style award where NIH expects substantial involvement and coordination with the funded group.

Is this opportunity considered a limited competition?

Yes. The FOA explicitly describes the opportunity as a limited competition with intentionally narrow eligibility.

Who is eligible to apply?

Only institutions that are current members of the CRN consortium supported by the NCI U19 cooperative agreement are eligible to apply.

Does the FOA expect participation from all CRN member institutions?

Yes. While one member institution will submit the application as the lead applicant, the FOA indicates it is expected that all current CRN member institutions will participate in the consortium activities supported by this award.

Which institution should submit the application as the lead applicant?

The FOA leaves the choice to the discretion of the eligible members. The lead applicant could be the current awardee institution or another qualifying CRN member institution.

Are foreign institutions eligible to apply?

No. Foreign institutions are explicitly ineligible under this announcement.

Are foreign components of U.S. organizations allowed?

No. The FOA states that foreign components of U.S. organizations are not permitted.

Is cost-sharing or matching required?

No. The FOA states there is no cost-sharing or matching requirement, meaning applicants are not required to commit non-federal funds as a condition of the award.

What is the estimated total funding amount?

The FOA lists an estimated total funding amount of $4,000,000.

What types of program areas does this opportunity relate to?

The opportunity is categorized under health and education-related research activities and is tied to multiple cancer-related CFDA program areas: cancer cause and prevention (93.393), detection and diagnosis (93.394), treatment (93.395), and cancer control (93.399).

When was the FOA posted and when did it close?

The FOA was posted on September 29, 2011. The original and current closing date is December 15, 2011.

When was the FOA archived?

The archive date listed is January 15, 2012.

Where was the announcement made available?

The FOA was made available through the NIH grants guide.

Who is the listed contact for access or linking issues?

The contact listed for access or linking issues is the NIH Office of Extramural Research webmaster at FBOWebmaster@OD.NIH.GOV.

How should this opportunity be understood at a high level?

The FOA is best understood as continued federal support to operate and expand CRN as a high-value, health-system-based cancer research resource, emphasizing data access across multiple integrated care organizations and the practical expertise needed to turn those data into credible, impactful cancer research.

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